Will 5-HTP Deplete My Dopamine Levels? (Short Version)

#supplements #dopamine #serotonin #brainhealth #liverhealth #functionalmedicine
'If I take too much 5 HTP will it deplete my Dopamine levels?'
Key Enzyme: aromatic amino acid decarboxylase
Long Version:
Should I Take L-Tyrosine and 5-HTP Together? (Serotonin and Dopamine Balance?)
• Should I Take L-Tyrosi...
The Benefits of 5-HTP
• What Are The Benefits ...
The Benefits of SAMe?
• What Are The Benefits ...
Are you questioning whether you need to take L-Tyrosine and 5-htp together? Some people are saying that if you take 5 HTP for depression, that you’ll make your symptoms worse if you don’t take 5-HTP and L-Tyrosine together.
Both 5-HTP and L-tyrosine work in the brain in ways that may enhance established treatments for certain brain-based conditions. L-tyrosine is a main ingredient of dopamine, epinephrine and norepinephrine, and 5-HTP triggers increased serotonin production. Serotonin is one of the main chemicals that produce feelings of happiness and well-being in the brain, and also helps regulate the appetite and control moods and sleep patterns. Dopamine, epinephrine and norepinephrine are chemicals called catecholamines that are responsible for the fight-or-flight response triggered by immediate danger or central nervous system stimulation. Low catecholamine levels have been linked to depression.
As encouraging as the partnership between these two chemicals may seem at this point, they come with some risk. L-tyrosine can trigger migraines and increase thyroid hormone production, and may increase the risk of blood-pressure-related complications in people taking MAOIs. At this time, people taking MAOIs or L-dopa refrain from taking L-tyrosine. Pregnant or breastfeeding women should not take 5-HTP, which can also cause seizures in those with Down syndrome. Typical 5-HTP side effects include drowsiness, heartburn, nausea, diarrhea and vomiting. The supplement should not be taken with MAOIs or other depression medication, or any medication that affects serotonin levels. It may also interact with St. John's Wort, SAMe, and L-tryptophan.
Mucuna Pruriens is an extract of the velvet bean plant that grows 3 - 18 meters in height. L-DOPA (levodopa) is usually synthetic and made in the lab.
The natural version of L-DOPA from Mucuna Pruriens is generally well-tolerated by most people. And the compounds in the plant are bio-identical to those chemicals naturally made in your body. Not so with synthetic L-DOPA.
Synthetic L-DOPA is metabolized into dopamine in your body by an enzyme called aromatic L-amino acid decarboxylase (AADC). And the majority of synthetic L-DOPA will be converted peripherally (not in the central nervous system and brain). This can cause problems.
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Dr. Jawad is a Board Certified Chiropractic Neurologist and Acupuncturist. In addition, a Diplomat for the American Chiropractic Neurology Board, Fellow of the American College of Functional Neurology as well as Fellow of the International Academy of Medical Acupuncture. He is a Certified Functional Medicine Practitioner.
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Пікірлер: 146

  • @Rob-bq6ek
    @Rob-bq6ek Жыл бұрын

    Best explanation on this subject I've seen. Too many other channels don't explain effectively the concerns with 5HTP.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Thank you for your support.

  • @morio9284
    @morio9284 Жыл бұрын

    Edit: my question was answered in the description of the long version and in the comments by Doctor. 5htp to tyrosine is 1:10 ratio, i. e. 100mg 5htp + 1.000 L-Tyrosine for a day. Before noon take L-Tyrosine, afternoon 5htp. L-Tyrosine only in empty stomach. 5htp or tyrosine therapy for only 3 to 5 weeks then 3 to 5 weeks break, then repeat. Maximum 600mg htp per day or lower. L-Tyrosine maximum 7.000g per day. Doctor, can you tell how to balance 5htp and L-Tyrosine? Is it "1:10" or "1:1"? For example i take 600mg 5HTP over the day, do i have to take 6.000mg L-Tyrosine then or is 500mg enough? And can i take L-Tyrosine also multiple times over the day or only before 16pm? Thank you very much for the information! 👍

  • @MrX-rr8cw
    @MrX-rr8cw2 жыл бұрын

    I like the new introduction. Nice way to change things around. Excellent video as always..

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    Glad you like it!

  • @MrGunner44ever
    @MrGunner44ever Жыл бұрын

    Great video, thank you! What is the ratio when taking L-Dopa and 5HTP together? Is it 2:1 (L-Dopa : 5htp)?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    www.reddit.com/r/anhedonia/comments/u2lny5/best_ratio_for_taking_ldopa_and_5htp_together_for/ L-Dopa is a prescription medication.

  • @BITTAPART2
    @BITTAPART26 ай бұрын

    Did anyone mention using a AAAD inhibitor like green tea extract, and what effect this might have on the serotonin/dopamine and the BBB?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    6 ай бұрын

    Great question. Do the research and post it back on this page. Looking forward to it....

  • @SK-dy2ll
    @SK-dy2ll2 жыл бұрын

    Hello there, I’ve been taking 600 mg in the morning and 600 mg at night for about 3-4 months I feel great, no side effects at all only positive outcomes it helps my mood swings tremendously and now I am going to add L tyrosine 500 mg It only started helping me when I increased my dose on lower does it wasn’t doing anything for me.

  • @T-19-

    @T-19-

    2 жыл бұрын

    Well that’s great to hear, I hope it works out for all of us who want to try it

  • @JFabree
    @JFabree Жыл бұрын

    I am a bit confused, are you recommending we take L-Tyrosine or Mucuna Pruriens plus 5-HTP if we want to improve sleep, mood, anxiety, etc?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    These are just recommendations on how to improve body functions.

  • @pigliatistopallozzo9820
    @pigliatistopallozzo98204 ай бұрын

    Hi,thanks for the video.can the same thing happen with melatonin?i noticed my tobacco intake increased around 30% exactlty when i started melat,maybe its a casuality maybe not im not 100 sure

  • @47SCIPIO
    @47SCIPIO Жыл бұрын

    So I guess my question would be, it doesn't seem through this presentation that 1, 100mg 5HTP once a day should have any adverse affects on dopamine levels. Would that be a correct statement? I was originally told by someone 5HTP was the way to go to keep dopamine levels up and balanced but it may seem that was false information?

  • @HeartFeltGesture

    @HeartFeltGesture

    10 ай бұрын

    Sounds false. 5-htp raises serotonin and in fact reduces dopamine. This is why dopamine must be supplemented simultaneously.

  • @P0Lak2012
    @P0Lak20125 ай бұрын

    Hey doc. Im taking 5htp since 3 and 1/2 years in high doses mostly 6g per day. Yes you heard right its prob 6gram sometimes more sometimes less mostly for anxiety and depression. Couldnt find any evidence on the internet that this is dangerous except that its possible in theory to develope heart fibriyosis. Any concerns? C

  • @davejustin4701
    @davejustin47012 ай бұрын

    Thanks for this great explanation (once again)! Just one remaining question; Does lowering or increasing Dopamine/Serotonin in this way only count for the brain or also for the entire body/ blood counts of Dopamine and Serotonin?

  • @kareemahmed7028
    @kareemahmed7028 Жыл бұрын

    Hello Doctor. I have essential tremor, not Parkinson's disease. When I hold a glass of water, my hands tremble and I feel embarrassed. When a problem occurs in front of me, my body trembles, my heartbeat increases, and I find it difficult to speak. A neurologist prescribed an anticonvulsant drug (Mysoline). It was an effective treatment and the tremor disappeared, but it had annoying side effects. Will tyrosine &5htp help my condition

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    This is more complicated to answer on a KZread page ----www.totalwellnessdupage.com --- schedule a consultation with me to discuss further.

  • @fitlifeconrad
    @fitlifeconrad Жыл бұрын

    OK I have a question for you. Can you take them at the exact same time five HTP with DL PA or tyrosine let's say you are low in both of them.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    take 5 htp before bed. Tyrosine in the morning.

  • @JD-wx3pk
    @JD-wx3pk2 жыл бұрын

    Thanks mate, great video

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    Glad you enjoyed it

  • @JD-wx3pk

    @JD-wx3pk

    2 жыл бұрын

    @@thejdocrealminute4648 helps heaps. Bought some 5htp today.. it's healthier than taking SSRIs in my opinion, especially if the primary reason for taking them is to boost serotonin.

  • @fitlifeconrad
    @fitlifeconrad Жыл бұрын

    Both of my Levels are low DOPA and SERETONIN - I find 5htp gives me energy vs relaxes me ever heard of this? and then for future take both at the same time to raise both>?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    I would first research the CAUSE of both being low.

  • @fitlifeconrad

    @fitlifeconrad

    Жыл бұрын

    LOW VIT b5, LOW VIT C, probally do not digest my proteins the way I need to .Resulting in low levels across the board, dopa/epi/norepi...need supporters like mucana/5htp/phenyl until body is converting the foods into them like its supposed to.@@thejdocrealminute4648

  • @vonboyage
    @vonboyage2 жыл бұрын

    Hi big fan from the UK. Your work is outstanding. Question. If someone was taking 50mg or 100mg 5-htp how much mucuna pruriens should be supplemented? Whats the ratio. Also where can you buy this mucuna pruriens supplementation. A safe source would be great.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    I recommend getting it on Amazon. You can take together. 100 mg/ 1000mg ...

  • @vonboyage

    @vonboyage

    2 жыл бұрын

    @@thejdocrealminute4648 excellent! if you have a leaky gut or chronic gastritis from H.pylori would they affect absorption of iron, b6, methylfolate and methylcobalamin, magnesium or zinc. If so any recommendations to somewhat make sure these nutrients are absorbed. Thank you so much for taking the time to read and reply.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    @@vonboyage Yes, --- fix the gut first.

  • @annace9273

    @annace9273

    Жыл бұрын

    ​​@@thejdocrealminute4648 dear dr if I Just start Mucuna for dopamine 400 mg in morning(wow good stimulation) 50-100mg 5htp for night is good ratio/balance for depression? I can't take antidepressant they cause NMS syndrome and akathisia. I am on benzo But i hope those supplements will support to go down with benzo safetely. BTW I have sfpn due to high doses of b6. So thats why I am on benzos. 😢

  • @missionimpossible143

    @missionimpossible143

    3 ай бұрын

    ​@@annace9273😢😢

  • @Stellamamma
    @Stellamamma Жыл бұрын

    Can I take 100mg 5HTP, 100mg magnesium glycinate at night, then l tyrosine 1000mg in the morning? Magnesium is a lifesaver for my period pains.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Most studies have been conducted on purified bile salts called TUDCA (taurodeoxycholic acid) and UDCA (ursodeoxycholic acid). These bile salts are naturally found in ox bile. Bile salts are stored in the gallbladder.

  • @diesel9650
    @diesel9650 Жыл бұрын

    Very good,thank you

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Thank you too!

  • @Tynnutza
    @Tynnutza Жыл бұрын

    Can be combined L-Theanine and 5HTP, I use 100mg each in the morning and evening? It will help for depression? For now for me I can't see very big changes after 3 weeks

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    I would recommend increasing your L-Theanine------adding GABA and Ashwaganda.

  • @ladibyrd
    @ladibyrd Жыл бұрын

    ahhhhh you're a legend thank you. I feel hypomanic today and i only had a bit of 5htp over the last 2 days before bed because i had insomnia. i finally got some sleep but feel way too good today. and getting frustrated by the speed of which things get done so that's a hypomanic symptom i'm aware of. i use macuna to help my facial ticks at night. do you think i should keep taking the 5htp?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Take 5 htp for a short time.

  • @ladibyrd

    @ladibyrd

    Жыл бұрын

    @@thejdocrealminute4648 ok, yeah i don't want to mess around with my thyroid, i already have nodules. i've bought some L-tryptophan to try tonight instead of the 5-htp, i'll probably get in touch with you for a consultation for some advice when i think i've sorted it out - for you to check

  • @joeblow1748
    @joeblow17483 ай бұрын

    Its calling being isolated because being in the wrong place at the wtong time.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    3 ай бұрын

    Correct.

  • @HananGrow
    @HananGrow2 ай бұрын

    I took 100 5-htp and it drained all my energy but was great for my anxiety. I hope I can find Mucuna Pruriens in where I live.

  • @kevinkuziw6801
    @kevinkuziw6801 Жыл бұрын

    @TheJDocRealMinute I've been taking 100MG x three times a day of 5HTP for what at the time I thought was anxiety, burnout and severe insomnia, and now PTSD around sleep. Im pretty sure its post partum depression though as I did not have sleep issues before and im just miserable without 5HTP. I tried to get off 5HTP over 3 weeks while simultaneously introducing more healthy carbs into my diet, I was feeling pretty good and sleeping better than ever, in fact I was down to 100mg x 2 times a day this summer. It turned into nightmare at night, it triggered severe anxiety & panic attacks and midnight tremors/sweating, I was also constipated all the time and waking up 4 times a night to poop but just couldn't go. Now that I was mostly caught up on sleep back on 5HTP, im struggling again with insomnia, though not as bad as previous. I take two whey protein shakes a day between meals and eat a pretty high protein diet to support my weight lifting workouts and yoga. I just started supplementing with 500MG tyrosine in the morning, my thyroid a few weeks ago was in the perfect/normal range. Am I taking enough tyrosine? I figured I should start small and see if my sleep improves?

  • @inspiradorupees3029
    @inspiradorupees302925 күн бұрын

    As Albert Einstein once said: Everything in moderation

  • @fredbloggs6080
    @fredbloggs60802 жыл бұрын

    How does something like Magnesium L-Threonate or Magnesium Acetyl-Taurate compare to 5-HTP in raising serotonin levels, and are these forms of magnesium safer?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    They work on different systems.

  • @fredbloggs6080

    @fredbloggs6080

    2 жыл бұрын

    @@thejdocrealminute4648 I was just wondering because studies in the last few years have shown that people who take SSRI medications have 33% increased mortality. And there was an experiment where mice whose serotonin production is knocked out lived significantly longer than normal mice. In numerous studies recently coffee consumption has been linked to reduced all cause early mortality and reduction in many diseases. Various factors have been put forth for this, including the effects of caffeine, and various polyphenyl antioxidants in coffee, including chlogenic acid, etc., but I wonder if the serotonin lowering the effects of coffee also play a part.

  • @self-purpose
    @self-purpose8 ай бұрын

    Question: should we take them at different times in the day if we take both, how do they compete? Thank you

  • @thejdocrealminute4648

    @thejdocrealminute4648

    8 ай бұрын

    You can take them at different times. How do they compete? Did you watch the video? Or watch this one....kzread.info/dash/bejne/eH6skrx9gb28pMY.htmlsi=L6L3UdCkmymbxEge

  • @bernardo0601ify
    @bernardo0601ify Жыл бұрын

    I'm thinking about taking 5htp...I based on dna results I have 5httlpr (ss) which is the short version and could be causing a dysregulated serotonin. It was recommended to take 5htp but I'm so skeptical of it not working

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Give it a try. Small dose at first.

  • @tietoinenyhteys
    @tietoinenyhteys Жыл бұрын

    I was thinking would it be kind of the same thing to just take less 5-htp that it is to take more 5-htp and l-tyrosine to balance the levels?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    It is the Enzyme that you have to be aware of.

  • @T-19-
    @T-19-2 жыл бұрын

    Hi doctor, is it okay to take 50-100mg of HTP with 400mg of Tyrosine?

  • @sincerelyrob4240
    @sincerelyrob4240Ай бұрын

    Does sertaline deplete such, as well?

  • @goygoy8441
    @goygoy844110 ай бұрын

    hello. can we take 5 htp with wellbutrin xl _? thank you

  • @chibby8903
    @chibby89032 жыл бұрын

    so is it okay to take both L-Tyrosine and 5-HTP? Is it recommended to take them at the same time, or separately (i.e. L-Tyrosine in the morning, 5-HTP in evening)? TIA

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    You can take them together in the morning. I recommend you split them up according to their mechanism.

  • @chibby8903

    @chibby8903

    2 жыл бұрын

    @@thejdocrealminute4648 thank you for your response!

  • @CsSee-dj3rg
    @CsSee-dj3rg11 ай бұрын

    Hi doc, I have adhd and taking Ritalin for it everyday, can I know if I start taking 5 htp would the Ritalin alone be enough to balance out my dopamine levels similarly like l-tyrosine?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    11 ай бұрын

    I am not sure I understand the question?

  • @CsSee-dj3rg

    @CsSee-dj3rg

    10 ай бұрын

    @@thejdocrealminute4648 would 5 htp + Ritalin balance my seratonin and dopamine levels, so I don’t have to take 5 htp + Ritalin + l tyrosine

  • @P0Lak2012

    @P0Lak2012

    5 ай бұрын

    ​@@thejdocrealminute4648he wants to know if methylphenidate is also good for balancing out dopamine levels - i am wondering this too.

  • @user-aprilfish

    @user-aprilfish

    5 ай бұрын

    I have the same question too. Ritalin will increase dopamine levels just like l-tyrosine

  • @ZeeGeeBee

    @ZeeGeeBee

    3 ай бұрын

    Just came across this channel while researching 5 htp. I’m on adderrall XR for ADD.. and I’m really wondering if I can start taking 5 htp and what’s the affect of these two on the dopamine serotonin balance. Were you guys able to find any answers on this topic? Any input is appreciated

  • @recklessvelociraptor2579
    @recklessvelociraptor25792 ай бұрын

    When developers accidentally put gym trainer skin on a doctor character

  • @jro6947
    @jro6947 Жыл бұрын

    So instead of taking TYROSINE AND 5-HTP can you take L DOPA AND 5-HTP ?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    kzread.info/dash/bejne/q4h-k62Rp86sfso.html

  • @smaymiller1142
    @smaymiller11422 жыл бұрын

    I take 500mg of l-tyrosine before I weight train, and before I drive as it helps with my bad focus because of ADHD. Should I start taking 500mg of 5htp Alongside this because I find myself extremely anxious and depressed a lot too? Or will the 5htp mess up my dopamine levels and make them even lower?? If it helps balance it out I’ll take both.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    It will help balance both.

  • @Kamasutraonmars
    @Kamasutraonmars9 ай бұрын

    This is too hard to understand, I wish you could have explained it in an easier to understand way, also after watching it, I still didn’t learn how much 5HTP to take with what to make sure i don’t deplete dopamine levels 🤷‍♀️

  • @thejdocrealminute4648

    @thejdocrealminute4648

    9 ай бұрын

    There is no research explaining the EXACT amount because EVERYONE is different. There is NO finite answer. If this is too confusing there are other videos out there that you can view. A doctor can measure the level of serotonin in your blood to check if it’s too high or too low. Broadly speaking it should be in the range of 101 to 283 nanograms/millilitre (ng/mL). In answer to the question: “Am I getting enough?” you may like to consider your diet and then decide. If you don’t eat meat, fish, eggs or cheese you may not be getting enough of the nutrients which produce 5-HTP and hence serotonin. Equally, some people’s metabolism is not as efficient as others, which then gives them a correspondingly lower amount of 5-HTP from its dietary precursor, tryptophan.

  • @Kamasutraonmars

    @Kamasutraonmars

    9 ай бұрын

    Oh I see. Thank you. So does that mean just eating meat or a protein shake will give me a balance of those amino acids that balance out dopamine and serotonin? I have adhd but also anxiety so I was thinking maybe sometimes my dopamine is low but other times my seratonin is low. But idk and I really don’t think my doctor would test it

  • @thejdocrealminute4648

    @thejdocrealminute4648

    9 ай бұрын

    No -- ONE shake is NOT going to do it. It has to be a lifestyle change. If you truly have the desire for the answer. Tell you Doctor to test you ....@@Kamasutraonmars

  • @joshua_finch
    @joshua_finch2 жыл бұрын

    What should the dose look like to keep balance? Is it like - if 500mg for tryptophan, then 500mg tyrosine? Also is L-phenylalanine too far back in the conversion chain to deplete serotonin?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    I would recommend --- 500 mg for both and see how you feel.

  • @gagecross25
    @gagecross25 Жыл бұрын

    Would I use this to lower excess dopamine, I have high dopamine I want to lower it.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Foods high in saturated fat (like palm oil and animal fat) can cause desensitization of dopamine receptors and are linked to lower reward response, leading to a lack of motivation and drive.

  • @stephanieeagle3584
    @stephanieeagle3584 Жыл бұрын

    Before 2006/2007 when I was 35/36 years old I was on Zoloft,Prozac and etc to from a doctor for low serotonin but I didn’t like there side effects. I also have had migraines since I was 2 years old. I was put on Lyrica for fibromyalgia in 2006/2007 I was 170 pounds and in that year gained 120 pounds and went to 290 pounds I weaned myself off of Lyrica and my oldest sister told me about 5-HTP helps migraines and with serotonin. So I started taking 5-HTP 50 mg for about a month and then upped it to 100 mg after that and was on it till 2009 when I became pregnant. I noticed 5-HTP when I was taking it I slept better and had a lot of energy. I had lost 90 pounds in 6 months while I was on 5-HTP. Since I had stopped using the 5-HTP and pregnancy weight and the death of my husband 16.5 days after our baby was born in 2010 I gained about 126 pounds since then. I now need to lose about 207 pounds at age 52. I also have vitamin D receptor gene mutation,pernicious anemia (b-12 deficiency),b-6 deficiency,MTHFR gene mutations and come to find out these deplete serotonin and etc. so this would explain why I had been put on antidepressants for low serotonin. But back then I didn’t know I had B vitamin methylation issues that I was born with. So with that being said I wanted to see if doing the 50 mg for a month then increasing it to 100 mg then 200 mg after that if that is good. I want to straighten out the low serotonin and dopamine and don’t want to throw either one off? I got myself 50 mg of 5-HTP to start out with and I also got a bottle of 200 mg Extended Release tablets (can I break the extended release tablets in half) so I only get 100 mg for awhile till my body gets use to it? 😊thank you

  • @greciatinoco8011
    @greciatinoco8011 Жыл бұрын

    if i have insomnia, severe anxiety and depression, and ocd, and i’m taking antidepressants, what should I take?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    You cannot take ANY of these supplements while on anti-depressants.

  • @Raiden-the-Goat32

    @Raiden-the-Goat32

    Жыл бұрын

    ​@@thejdocrealminute4648 Why ? I ask because i have taken these supplements while on an antidepressant and have had no negative effects from them. So is their some risk i did not encounter? I seen you're reply to the person who left the comment and am kinda worried.

  • @christine41861

    @christine41861

    7 ай бұрын

    @@thejdocrealminute4648 😲

  • @jochy67
    @jochy67 Жыл бұрын

    Hey does an SSRI also deplete dopamine and other neurotransmitters or not?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    SSRI antidepressants work by boosting circulating levels of serotonin, a mood-regulating neurotransmitter that also inhibits desire. The drugs also decrease dopamine, a neurotransmitter involved in a wide range of cognitive and behavioral processes, among them desire and arousal. SSRIs block the reabsorption (reuptake) of serotonin into neurons. This makes more serotonin available to improve transmission of messages between neurons. SSRIs are called selective because they mainly affect serotonin, not other neurotransmitters

  • @jochy67

    @jochy67

    Жыл бұрын

    @@thejdocrealminute4648 can i get help from you with 5htp usage together with the dopamine stuff?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    @@jochy67 www.totalwellnessdupage.com --- schedule a consultation for 20 minutes

  • @charleneelkington-nw2ux
    @charleneelkington-nw2ux Жыл бұрын

    Hey doc is saffron an alternative to 5-htp?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Saffron extract may improve symptoms of depression, but more study is needed. High doses can cause significant side effects.

  • @kittel-dev
    @kittel-dev2 жыл бұрын

    Wait a minute. If AAAD is used for L-Tryptophan to 5HTP conversion and L-Tyrosin to L Dopa conversion - should 5htp not help if u suffer from psychosis with a lot of dopamin in your brain?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    Schizophrenia. Early research suggests that taking 800 mg to 6 grams of 5-HTP daily with carbidopa for 90 days might improve schizophrenia symptoms in some young men. That is A LOT of 5 HTP. www.ncbi.nlm.nih.gov/pmc/articles/PMC3415362/

  • @bblack.orchidd
    @bblack.orchidd2 жыл бұрын

    Does anyone experience trouble sleeping when taking 5 htp? I had my first 100mg dose yesterday and kept waking up in the night. Interested to see if that continues to happen.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    This is rare. This can produce a sudden spike in serotonin levels and cause shivering and anxiety, which can keep you awake. I would suggest to lower the dosage until your body gets used to it. In addition, include 100 mg of B6 and 200 mg of Magnesium Glycinate.

  • @bblack.orchidd

    @bblack.orchidd

    2 жыл бұрын

    @@thejdocrealminute4648 thank you very much for the advice, I will add the vitamin b6 and magnesium to my intake. Luckily I had no problems sleeping at all the second night, so I guess it must have been my body getting used to it.

  • @dustinmcfall641

    @dustinmcfall641

    2 жыл бұрын

    It effects my sleep as well. If I take it earlier in the day I don’t have issues at night. Hope that helps!

  • @bblack.orchidd

    @bblack.orchidd

    2 жыл бұрын

    @@dustinmcfall641 ah yes I realised that my body was just getting used to it, I do sleep very well with now

  • @zincerish

    @zincerish

    Жыл бұрын

    ​@@thejdocrealminute4648 isn't 100mg b6 really high?

  • @BrokennessAndBeauty
    @BrokennessAndBeauty2 жыл бұрын

    5HTP works within one hour for me. I use it intermittently because of this reason. I’m scared. I only take 10mg-50mg MAX

  • @Seek147.

    @Seek147.

    Жыл бұрын

    Same here lol I took it it worked like in an hour

  • @slickrick5596

    @slickrick5596

    Жыл бұрын

    @@Seek147. did it decrease your libido?

  • @EchterBonito
    @EchterBonito Жыл бұрын

    I take 200mg since 2 years… should i stop?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Yes -- I would recommend.

  • @harislko71
    @harislko71 Жыл бұрын

    Do high level of 5ht reduce dopamine pre synaptic,plz reply.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Side effects of 5-HTP are generally mild and may include nausea, heartburn, gas, feelings of fullness, and rumbling sensations in some people. At high doses, serotonin syndrome, a dangerous condition caused by too much serotonin in the body, could develop. Administration of 5-HTP alone depletes catecholamines (dopamine, norepinephrine, and epinephrine). When dopamine depletion is great enough, 5-HTP will no longer function. www.ncbi.nlm.nih.gov/pmc/articles/PMC3415362/#:~:text=Administration%20of%205%2DHTP%20alone%20depletes%20catecholamines%20(dopamine,%2C%20norepinephrine%2C%20and%20epinephrine).&text=When%20dopamine%20depletion%20is%20great,HTP%20will%20no%20longer%20function.

  • @harislko71

    @harislko71

    Жыл бұрын

    Thankyou sir ,my wife having problem of anxiety etc was given escitalopram almost 3 years .latter she developed some bradykinisia,no swaing in arm etc ,and when the drug was tappered the problem more worsened she has got freezing of gait too. Now the escitalopram has been totally removed ,but she has still Parkinson type problem .will you please explain what is it ,and want should be done ,thanking you .

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    @@harislko71 That is something that I cannot explain with just this information. Sorry -- I would suggest keep doing your research on this situation and find an excellent Doctor to help heal her.

  • @harislko71

    @harislko71

    Жыл бұрын

    Ok thanks sir.

  • @Jon-hx7pe
    @Jon-hx7pe2 жыл бұрын

    does l-tryptophan also deplete dopamine?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    Not directly.....

  • @Jon-hx7pe

    @Jon-hx7pe

    2 жыл бұрын

    @@thejdocrealminute4648 so it's safer than 5htp?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    @@Jon-hx7pe I would recommend 5 HTP because there is a limit that your body will absorb the tryptophan.

  • @Jon-hx7pe

    @Jon-hx7pe

    2 жыл бұрын

    @@thejdocrealminute4648 tried htp a long time ago to no effect. i think different forms affect people differently to tryptophan may be worth a try

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    @@Jon-hx7pe include Vitamin B6 and Magnesium Glycinate....

  • @brahimdreamz9442
    @brahimdreamz9442 Жыл бұрын

    I have hypothyroidism and adhd can i take 5hdp

  • @FrozenAuroras

    @FrozenAuroras

    4 ай бұрын

    Have u asked ur doctor? It's been a year

  • @ZeeGeeBee

    @ZeeGeeBee

    3 ай бұрын

    I have both as well and take thyroid meds and adderrall XR.. I’m searching for this answer as well. Were you able to find any answers?

  • @ifranchisebusinessbylegitb4325
    @ifranchisebusinessbylegitb43252 жыл бұрын

    Is it free consultation?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    It is explained via www.totalwellnessdupage.com ---> Book Now.

  • @JulyManon
    @JulyManon2 жыл бұрын

    Hi doctor, I was prescribed bupropion XL 150mg and have taken it for 2 months without a problem, until I added in Mucuna Pruriens for a total of only 1-2 times, and started experiencing side effects. I began having tics, and twitches throughout my body, it's like an itch or urge to move involuntarily, like tourette's syndrome but milder. I wonder if these are neurotoxic combo? I hope I didn't blow some screws inside my brain and my dopamine system with this. I've stopped taking them for many months now, the tics and twitches are still here. Though what's odd is that I've taken bupropion separately for 2 months and never had this symptom, same to Mucuna Pruriens, I've taken Mucuna pruriens on and off many times in the past alone, and no issues, it's only when I combined those together then I had those effects.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    Do not take both of them.

  • @JulyManon

    @JulyManon

    2 жыл бұрын

    @@thejdocrealminute4648 Can I recover? I took them together 2 times total, and it feels like permanent damage.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    @@JulyManon Only time will be able to answer that question. See you Doctor if the symptoms persist.

  • @heidih3048

    @heidih3048

    Жыл бұрын

    @@JulyManon These symptoms can happen with antipsychotic medication. The medication has to be stopped right away, or the symptoms can be permanent. Hopefully you stopped right away. In any case, how are you doing now?

  • @user-rp2ui8ro4r

    @user-rp2ui8ro4r

    7 ай бұрын

    Did u recover??

  • @bblack.orchidd
    @bblack.orchidd2 жыл бұрын

    I do struggle with anxiety and depression and since taking 5htp it helped me tremendously. I am starting to take L-tyrosine aswell to keep the balance but I would like to know if I can take these everyday? Or if I should use them for a few days and give it a break? Not too sure and I haven't found any good answers on this.

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    Yes, you can take these everyday. However, due to the enzymes involved in breaking them down --- You want to ease off to give your body a break.

  • @heidih3048

    @heidih3048

    2 жыл бұрын

    @@thejdocrealminute4648 do you mean they stress the liver?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    @@heidih3048 Did you watch the videos?

  • @heidih3048

    @heidih3048

    2 жыл бұрын

    @@thejdocrealminute4648 Yes, I just wanted to clarify that the reference to the "enzymes involved" is a reference to liver function (I thought that would be helpful to make clear to those without medical knowledge-- I am a nurse, so I am familiar, but thought it might be helpful to the lay reader to make the liver involvement clear).

  • @thejdocrealminute4648

    @thejdocrealminute4648

    2 жыл бұрын

    @@heidih3048 Yes, liver health is very important. I am referring to the Aromatic L‐amino Acid Decarboxylase enzyme.

  • @helenatroy33
    @helenatroy336 ай бұрын

    But what is too much 5htp?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    6 ай бұрын

    When taken by mouth: It is possibly safe to take 5-HTP in doses of up to 400 mg daily for up to one year. The most common side effects include heartburn, stomach pain, nausea, vomiting, diarrhea, drowsiness, sexual problems, and muscle problems. Large doses of 5-HTP, such as 6-10 grams daily, are possibly unsafe.

  • @helenatroy33

    @helenatroy33

    6 ай бұрын

    @thejdocrealminute4648 thanks for the reply! I take only 100mg at night and boy is it effective!

  • @laibaatif1733
    @laibaatif1733 Жыл бұрын

    I started taking 5 htp and it makes me more anxious and my heat beats fast all the time 😢I m tired of this anxiety that something gonna happen right noww

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Too much 5-HTP in your body can cause a spike in serotonin levels, resulting in side effects such as: anxiety. shivering. serious heart problems.

  • @zincerish

    @zincerish

    Жыл бұрын

    ​@@thejdocrealminute4648 what is the recommend dose?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    @@zincerish kzread.info/dash/bejne/gougrMqphsfOqdI.html

  • @davidcoomber4050
    @davidcoomber405011 ай бұрын

    Looks like a Spaghetti western

  • @ranchal628
    @ranchal628 Жыл бұрын

    I think a lot, whenever I go to sleep at night, I get a lot of good and bad thoughts, I do not know when I sleep, I do not know when I have a headache at bedtime. Should I take 5htp?

  • @thejdocrealminute4648

    @thejdocrealminute4648

    Жыл бұрын

    Give it a try. Try it for 2 weeks and see how you feel.