Thanks so much for watching and supporting the channel. Here are the references for the studies discussed: Ketone Bodies World Health Organization . Guideline: Sodium Intake for Adults and Children. World Health Organization; Geneva, Switzerland: 2012. pp. 1-46. Wright JA, Cavanaugh KL. Dietary sodium in chronic kidney disease: a comprehensive approach. Semin Dial. 2010 Jul-Aug;23(4):415-21. Verma A, Popa C. The Interplay Between Dietary Sodium Intake and Proteinuria in CKD. Kidney Int Rep (2023) 8, 1133-1136 Ketone body overview Mudaliar S, Alloju S, Henry RR: Can a Shift in Fuel Energetics Explain the Beneficial Cardiorenal Outcomes in the EMPA-REG OUTCOME Study? A Unifying Hypothesis. Diabetes Care, 39: 1115-1122, 2016 10.2337/dc16-0542 Balasse EO, Fery F: Ketone body production and disposal: effects of fasting, diabetes, and exercise. Diabetes Metab Rev, 5: 247-270, 1989 10.1002/dmr.5610050304 Ketones and ATP Tomita I, Kume S, Sugahara S, Osawa N, Yamahara K, Yasuda-Yamahara M, Takeda N, Chin-Kanasaki M, Kaneko T, Mayoux E, Mark M, Yanagita M, Ogita H, Araki SI, Maegawa H: SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition. Cell Metab, 32: 404-419 e406, 2020 Ketones and PCKD Torres JA, Kruger SL, Broderick C, Amarlkhagva T, Agrawal S, Dodam JR, Mrug M, Lyons LA, Weimbs T: Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease. Cell Metab, 30: 1007-1023 Ketones and AKI Mikami D, Kobayashi M, Uwada J, Yazawa T, Kamiyama K, Nishimori K, Nishikawa Y, Morikawa Y, Yokoi S, Takahashi N, Kasuno K, Taniguchi T, Iwano M: beta-Hydroxybutyrate, a ketone body, reduces the cytotoxic effect of cisplatin via activation of HDAC5 in human renal cortical epithelial cells. Life Sci, 222: 125-132, 2019 Ketones and HTN Chakraborty S, Galla S, Cheng X, Yeo JY, Mell B, Singh V, Yeoh B, Saha P, Mathew AV, Vijay-Kumar M, Joe B: Salt-Responsive Metabolite, beta-Hydroxybutyrate, Attenuates Hypertension. Cell Rep, 25: 677-689 e674, 2018

@gengmabiscay3633

5 ай бұрын

Doc I'm a pilipino dialysis patient. I want to know if ok for me the intermittent fasting???

I finally found someone on KZread that I understand and want to study and follow.

Thank you very much Dr. Sean Hashmi for such interesting information. Really very necessary for all of us who have PKD and are interested in doing everything possible to take care of ourselves as much as possible and ensure that the progression of our PKD is as slow as possible. Thanks for your generosity!!! A big hug from Sweden. (Excuse my English. I do not speak English language, and I use google translate to translate)

❤️ Thank you, Dr. Hashmi.

@SELFPrinciple

6 ай бұрын

You are very welcome :)

Very informative... Thanks for presenting

@SELFPrinciple

6 ай бұрын

Thank you for the support!

Thanks

@SELFPrinciple

6 ай бұрын

No problem.

ADPKD kills my family for generations with a recent loss and currently 3 of us confirmed and in the grave queue. I'm in Stage 2. Please as Dr Hashmi, so other reading, any insights, ideas, help will be greatly appreciated. I'm doing whatever I can, organic-enthusiasts grown plant based diet, living on intermittent 18h fasting every other day, exercising for 30min after at least 1 out of 3 meals, eating the lower end of salt recommendations for ADPKD, no sugar, processed food and limited carbs. Keeping stress levels in tick, ... Anything, ANYTHING else you'll recommend? And a HUGE thank you for all these information and research, very helpful!

@SELFPrinciple

6 ай бұрын

You are doing an amazing job! Please talk with your nephrologist to also discuss the medication options and see if its right for you or not.

@jennifers2233

5 ай бұрын

Make sure your blood is akaline. This is extremely important. Renatrophin pmg - help support cell regrowth and repair kidney gland function. Ginger tea (non gmo, organic) Milk thistle Spirulina ( for detox) Lemon in your water Praying for you to heal and feel good. 😊❤🙏

41M, alcoholic liver disease, gfr 35, bp 135/85, proteinuria +3,, creatine 2.2-2.5. amlodipine 10mg. Just did biopsy which showed scarring. iGA negative. Low sodium diet and aa much plant based as possible. Any further thoughts/recommendations please

@SELFPrinciple

6 ай бұрын

There are so many things here. Its very important to talk with your nephrologist and focus on getting the protein in the urine down, lowering blood pressure and any risk factors you may have.

@jennifers2233

5 ай бұрын

yes, please read my comment above. prayers for you. 🙂

Hi, I’m on one meal a day for 6 months, is any effect will be on my kidneys function?

@SELFPrinciple

6 ай бұрын

Not that I am aware of. But we don't advise one meal a day.

Greetings from Spain 😅

@SELFPrinciple

6 ай бұрын

Wow, awesome! Thank you for checking out the channel!

Why such a hate of a ketogenic diet that you call a crazy diet? I will agree with you that exercise is important, as well as sleep. But a ketogenic diet, once mastered, is a heck of a lot easier than one hour of physical exercise each day when you have a busy life and a long commute. Keto is not back as you say and is not recent - did you just discover it? It is state of the art and used for instance in the treatment of a variety of mental health issues. Why scare people with ketoacidosis which is a rare event? Btw I have a T1D friend who, under a knowledgeable doctor's control, reduced her injected insulin by FIFTY percent on a ketogenic diet. I strongly suggest you get your knowledge on the ketogenic lifestyle up to date or divulge a conflict of interest. If there are other reasons why you are so reluctant about the keto lifestyle, then they are probably even worse.