Awesome, two of my favorite people on podcasts

@Thebusysuperhuman

2 ай бұрын

Thank you - Dr Seneff is epic in this one

Always learn something important when I listen to Drs. Pugh and Seneff.

🎯 Key Takeaways for quick navigation: 00:00 *🧬 Mitochondrial dysfunction is linked to numerous diseases due to excessive deuterium in cells, impacting immune function and allowing viruses to multiply.* 01:22 *🤝 Dr. Stephanie Seneff discusses various topics including methylation pathways, deuterium, gut microbiome's role, and the importance of natural nutrients.* 03:45 *💧 Deuterium, a heavy isotope of hydrogen, interferes with metabolic reactions and mitochondrial function, but deuterium-depleted water can offer health benefits.* 05:38 *🧠 Methylation pathways, crucial for biology, involve gut microbes producing methane, which contributes to low deuterium levels in essential nutrients like methionine.* 11:25 *🤔 Deuterium's unique properties affect its interaction with biological systems, and its depletion is crucial for maintaining mitochondrial health.* 17:31 *💡 Saliva, breast milk, and certain foods like butter can contain low deuterium levels, offering insights into dietary strategies for reducing deuterium exposure.* 20:55 *🍏 Deuterium, a heavy form of hydrogen, is present in various foods, with fruits being high due to their growth factor properties during mating season.* 22:32 *🥤 Gel water, found in the body's collagen network, traps deuterium, leading to lower deuterium levels in fluid water.* 24:10 *💧 Deuterium-depleted water, obtained through freezing cycles or purchased, can help maintain low deuterium levels in the body.* 26:28 *🩸 Endothelial cells monitor blood flow using electromagnetic signals from red blood cells, adjusting sulfate and nitrate levels to maintain proper viscosity.* 28:49 *🧠 Glyphosate disrupts cobalamin (vitamin B12) production, leading to potential brain-related issues like Alzheimer's-like symptoms.* 32:58 *🌱 Glyphosate, commonly found in processed foods and fast foods, is a pervasive toxin in the American diet, potentially contributing to systemic B12 deficiency and fertility issues.* 34:22 *👶 Glyphosate exposure, especially during pregnancy, is implicated in developmental disorders like autism, potentially starting the damage in utero.* 37:20 *🔄 Autism may be reversible, as evidenced by cases where individuals have fully recovered through dietary changes, supplements, and methylation pathway support.* 39:11 *🔬 Autism may involve sulfur mismanagement, with glyphosate disrupting sulfate pathways, impacting brain function and potentially inducing a state akin to hibernation.* 40:45 *🔄 Cholesterol, vitamin D, and sex hormones are typically sulfated during transport, making them water soluble and aiding in their transportation.* 42:54 *🏥 HDL levels may indicate leaky gut, as the liver's ability to produce HDL depends on sulfate availability.* 46:17 *🔄 High homocysteine levels can indicate a sulfate deficiency, as inflammation is needed to convert homocysteine into sulfate.* 52:25 *🌱 Glyphosate, used widely in agriculture, suppresses methionine synthesis in microbes and plants, leading to sulfate deficiencies.* 57:28 *⚠️ Glyphosate use in commercial marijuana farming can lead to contamination, posing risks to consumers and the environment.* 01:00:47 *🦴 Glyphosate contamination of collagen can lead to joint and bone issues by substituting glycine and disrupting the collagen's structure.* 01:01:43 *🧬 Proline, found abundantly in collagen, traps deuterium, playing a crucial role in maintaining its structure.* 01:04:18 *🔄 Enzyme TE removes methyls from DNA, converting them into other molecules, contributing to mitochondrial function by producing succinate.* 01:08:25 *⚡ Cancer cells shut down mitochondria to avoid DNA damage, relying on lactate production for energy.* 01:10:32 *💊 Synthetic supplements with methyl groups may contain high levels of deuterium, potentially harming mitochondrial function.* 01:17:45 *🐭 Methionine deficiency in rats led to healthier mitochondria due to microbial synthesis of methionine, highlighting the potential harm of synthetic methionine supplements.* 01:20:05 *🧪 Synthetic vs. natural supplements often go unnoticed in studies, impacting results.* 01:21:16 *🌿 Natural choline and melatonin are beneficial, but synthetic forms may lack essential methyls.* 01:22:39 *💤 Glyphosate disrupts tryptophan synthesis, affecting serotonin and melatonin production.* 01:23:08 *⚙️ Melatonin aids mitochondrial repair and controls hormonal balance, but synthetic forms might not be beneficial.* 01:24:34 *🔬 The body's intricate processes, including enzyme activities, become clearer when considering deuterium dynamics.* 01:27:21 *🐄 Glyphosate affects gut enzymes in cows, leading to methane emissions and formaldehyde toxicity.* 01:29:55 *💊 Many supplements are chemically synthesized, potentially lacking natural balance and causing unintended effects.* 01:31:30 *🧲 Glyphosate may contribute to the formation of trimethylamine oxide (TMAO), impacting gut health and overall wellbeing.* 01:34:15 *⛏️ Glyphosate acts as a chelator, binding to minerals and affecting their absorption and utilization in the body.* 01:38:54 *🌈 Red light and blue light influence deuterium behavior, with red light helping deuterium stay within structured water or gel water, which stiffens it, while blue light may exacerbate deuterium-related issues.* 01:39:36 *🧩 Collaborative discussions with knowledgeable peers often lead to "Eureka moments," enhancing understanding and sparking new avenues of inquiry.* 01:40:57 *📚 Dr. Seneff aims to write a book on deuterium if she can find a publisher interested in delving into the scientific complexities surrounding the topic.* 01:42:33 *🗣️ Dr. Seneff values sharing information freely to advance scientific understanding, prioritizing the dissemination of knowledge over personal recognition.* Made with HARPA AI

@OpenlyBritish

2 ай бұрын

THANK YOU!!!!!!!!!

@Thebusysuperhuman

2 ай бұрын

Thank you Lukas - I can add this to the description and I think I can also time stamp after upload

“All disease, at some period or other of its course, is more or less a reparative process, not necessarily accompanied with suffering: an effort of nature to remedy a process of poisoning or of decay, which has taken place weeks, months, sometimes years beforehand, unnoticed.” - Florence Nightingale

@eugeniebreida1583

Ай бұрын

erosive autoimmunity, and cancer - two examples that throw out Nightingale’s optimistic hypothesis.

@carolann2930

3 күн бұрын

@@eugeniebreida1583cancer & especually AI didn’t exist in meaningful numbers then.

We also much appreciate your sponsors as they support us in having the opportunity to hear brilliant minds.

@Thebusysuperhuman

2 ай бұрын

Thank you !!! That comment means a lot

I love this...amazing talk. Would be great to do a live with Seneff and Kruse and Max! Would love to know more about deuterium levels in fertilizers. Back in WW2 as Dr. Seneff mentions about the studies done with deuterium because it was used in nuclear weapon development. But what a lot of people don't know is that it was a natural byproduct of fertilizer production. So if we are using fertilizer (even in organically grown crops) are we introducing deuterium uptake into the plant material itself? Or even animal feed sourced from fertilizers would naturally create meat high in deuterium levels. An interesting agricultural study would be testing deuterium levels in all types of crops grown. I'm guessing we would find crops grown with organic compost or permaculture / biodynamic farming and the like would naturally produce low deuterium plants.

@Thebusysuperhuman

3 күн бұрын

That wont happen as too much of Dr Seneffs work has been borrowed so it would be a very awkward live

Like to see Stephanie and Dr Kruse together! Please!!

@Thebusysuperhuman

2 ай бұрын

Haha lots of reasons why that won’t likely happen - Id love to see TS Wiley & Dr K

Thank you both for your curiosity, brilliance and generosity.

@Thebusysuperhuman

Ай бұрын

thank you

Cholesterol sulfates are involved in various psychological functions such as skin barrier functions, cell membrane stability and antioxidant defense. However it is not yet well understood at this time . ❤. Eyes mind heart and soul wide open. NO FEAR!

Dr. Sara, Thank you so much for this discussion! It explains so much. It is so hard and so expensive to get away from sugar and contaminates here in the U.S.. Thank you for making your channel as understandable as possible for non scientists like me.

Great content. What a lovely human being Stephanie is. Thanks Sara.

@Thebusysuperhuman

Ай бұрын

I love Dr Seneff

On these topics, you and Seneff are two of my favorites. You both are able to go deep while remaining clear and coherent. In particular, this is one of my favorite discussions I've come across in this area. I'm on my second listen. S eneff's view on supplements has been an eye-opener for me. But I like your level-headed view as well. It's not a big deal that we've done harmful things in the past. Just do better going forward. The body is effective at healing, if we allow it.

@Thebusysuperhuman

11 күн бұрын

Yes I like talking to Dr Seneff as she is a polymath and she is really nice too

Long time waiting for this one. Thank you!

❤ Dr. Stephanie Seneff, she's absolutely amazing! Thank you!

@Thebusysuperhuman

2 ай бұрын

Our pleasure!

Awesome Sara!

Mind twisting great talk. Thank you both ❤

@Thebusysuperhuman

Ай бұрын

Our pleasure!

Amazing..in awe of your knowledge & learned a lot. Thank you

@Thebusysuperhuman

Ай бұрын

My pleasure!

Back for the re-match - outstanding 🏆

@Thebusysuperhuman

2 ай бұрын

Yes Dr Seneff went crazy delivering gems

fantastic!

So much good helpful information to ponder❤️thank you for sharing worthwhile knowledge to think about🐸

@Thebusysuperhuman

Ай бұрын

Glad it was helpful!

So many gems in this discussion ❤

@Thebusysuperhuman

Ай бұрын

Dr Seneff was very generous !

This was a wonderful discussion! I especially enjoyed the discussion on methylation and glyphosate. I have been healing paradoxical B12/cobalamin deficiency (where it is high in the serum but cannot be used), according to Gregory Russell Jones' research, which explains the need to replete iodine, molybdenum, selenium, and B2 in order to use B12. Interestingly, he works mostly with autistic children. I am having great success. That being said, I also eat an animal based diet and do not have much glyphosate exposure.

@Thebusysuperhuman

27 күн бұрын

Thank you for sharing your personal B12 journey as it’s a very nuanced topic

Great conversation… I’d love to hear you talk to Harry Serpanos who healed his heart and lung fibrosis with taurine . He advocates high taurine supplementation and I’d be interested to hear you flesh the pros and cons 😊

@Thebusysuperhuman

2 ай бұрын

Yes he is on my channel aleady if you look back to last year - I love Harry

@realitychick4502

2 ай бұрын

@@Thebusysuperhuman oh great! I’ll definitely search for that thank you ☺️

@Thebusysuperhuman , is litewater readily available in the u.k ? Its a us company so is shipping usurious :s . great podcast thanks to both

You are a butt kicker Sara! great work! I was wondering if you are able to host these conversations on a podcast platform such as the podcast app so they can be listened to outside of KZread

@Thebusysuperhuman

2 ай бұрын

Yes I’m setting it up in anchor and I also have substack now where I can put podcasts

@eugeniebreida1583

2 ай бұрын

I like them here on YT, as we can discuss w/others after viewing or further research ❤

@joshs.8003

2 ай бұрын

@@Thebusysuperhuman that’s great Sara. Thanks again for putting great content out into the world

@joshs.8003

2 ай бұрын

@@eugeniebreida1583 I think the comments on KZread are great as well and just hope that the content can be distributed on additional platforms as well such as the podcast I requested so we can listen to it on audio away from Wi-Fi which is not healthy if we spend too much time on it. With Podcasts, you can download them off-line and listen to them without being exposed to EMF

Sara, which blue blocking glasses brand do you have? Thanks 🙏

@Thebusysuperhuman

2 ай бұрын

Those are bon charge but I also really like prisma which is Dr Wunch brand

@TheReminderChannnel

2 ай бұрын

@@Thebusysuperhuman thank you, much appreciated 🙏

I wonder if there could be an association with deuterium and lymphedema and other fluid retention

Amazing information 🤩 anyone please sum up the practical applications 🙏

Such a great talk. What’s your thoughts on Master Amino Acid Pattern (MAP) they are fermented aminos that have decades of studies on them. Hoping it still counts as natural methionine so doesn’t cause the aging issue?!

@Thebusysuperhuman

Ай бұрын

I’m not sure as I’ve never used them. A colleague of mine likes aminos

I’m not a scientist but this is an amazing conversation and so informative and accessible, thank you 🙏

@Thebusysuperhuman

Ай бұрын

I’m glad you enjoyed it and the citizen scientists often know more than the real ones

Organic molecule supplements not good. What supplements are ok? I am taking Vital's glycine and MSM - yes or no?

🎯 Key Takeaways for quick navigation: 05:23 *🦠 Mitochondrial dysfunction is linked to various diseases due to excessive deuterium, impacting immune cells' ability to clear viruses.* 08:10 *🧬 Deuterium, a heavy hydrogen isotope, interferes with mitochondrial function, leading to various health issues.* 10:59 *🔄 Enzymes in the body discriminate against deuterium, favoring regular hydrogen, crucial for normal biological reactions.* 13:30 *🧪 Gut microbes produce hydrogen gas, depleted in deuterium, crucial for methylation pathways and overall health.* 16:33 *🦠 Viruses, like COVID-19, may trap deuterium, affecting mitochondrial health and immune responses.* 17:31 *💧 Saliva, breath, urine, and blood tests can indicate deuterium levels, with lower levels considered healthier.* 20:55 *🍏 Fruits high in deuterium serve as growth factors, particularly during mating season, while vegetables vary in deuterium content. Fats tend to have lower deuterium levels.* 23:40 *🏞️ Glacier water has lower deuterium levels, around 90 parts per million compared to 155 parts per million in seawater, making it a potential source of deuterium-depleted water.* 24:10 *💧 Deuterium-depleted water can be obtained through specialized products or by repeatedly freezing and discarding ice, albeit with significant patience and effort.* 26:15 *🌊 The body maintains a delicate balance of gel and fluid water, crucial for proper blood circulation, with signaling mechanisms involving nitrate and sulfate ions to modulate viscosity.* 29:46 *🧩 Glyphosate disrupts the methylation cycle and cobalamin (B12) production, contributing to various dysfunctions, including brain-related issues like Alzheimer's-like symptoms.* 32:58 *🥗 Glyphosate contamination is widespread, found even in fast food, posing a significant health risk, particularly for children, potentially leading to systemic B12 deficiency and fertility issues.* 37:20 *🧠 Autism has been linked to sulfate deficiency and disrupted sulfur metabolism, suggesting potential for recovery through dietary interventions and addressing underlying biochemical imbalances.* 40:05 *🔍 Glyphosate disrupts sulfo transferases, enzymes essential for sulfate attachment to carrier molecules.* 40:45 *🔄 Sulfate, a crucial universal donor, is attached to ring molecules like cholesterol and hormones, aiding in their transport and solubility.* 41:28 *💧 Cholesterol sulfate in HDL particles forms a protective layer, reducing oxidation and glycation damage, crucial for heart health.* 42:40 *🚨 Low HDL levels may indicate gut issues due to sulfate deficiency, essential for gut lining health.* 46:29 *💡 High homocysteine levels could signify sulfate deficiency, leading to cardiovascular risks due to impaired sulfate synthesis.* 49:28 *🤔 Inflammation occurs to convert homocysteine to sulfate, indicating a sulfate deficiency, crucial for cholesterol sulfate synthesis.* 54:04 *🌱 Organic foods contain less glyphosate, but contamination is still possible, emphasizing the importance of careful sourcing.* 57:28 *⚠️ Marijuana cultivation with glyphosate is a concern, potentially contaminating the product and nearby water sources.* 58:53 *🌾 Developing new herbicides may not solve the issue as glyphosate has unique and cumulative toxicities, impacting various diseases' rise.* 59:50 *🦴 Glyphosate can disrupt collagen structure, leading to joint and bone issues.* 01:01:58 *🧬 Proline, a key amino acid in collagen, is unique in its ability to trap deuterium, crucial for collagen's structure.* 01:03:23 *🧪 An enzyme in collagen may selectively avoid deuterium, maintaining the structural integrity of the protein.* 01:05:00 *🥩 Proline residues in collagen might enrich collagen with deuterium, potentially affecting structural and functional properties.* 01:06:25 *🧠 Alzheimer's disease could be linked to deficiencies in enzymes involved in proline metabolism and deuterium handling.* 01:07:17 *💊 Deuterium-depleted water shows promise as a complementary treatment for cancer, possibly by altering cancer cell metabolism.* 01:11:01 *🔬 DNA methylation may contribute methyl groups to mitochondrial processes, potentially influencing cancer cell metabolism and progression.* 01:14:26 *🔄 Methionine supplementation may have implications for longevity, as synthetic sources might contain high levels of deuterium, impacting cellular processes.* 01:18:53 *⚠️ Synthetic methionine supplementation may lead to mitochondrial dysfunction and oxidative damage due to deuterium contamination.* 01:19:08 *🧬 Excessive methionine intake can populate DNA with methyl groups containing high deuterium levels, damaging mitochondria.* 01:19:50 *🤔 Critical analysis of studies is necessary, especially when synthetic substances are involved, as they may not reflect natural processes accurately.* 01:21:30 *💊 Natural choline and melatonin are beneficial, but synthetic versions may contain high deuterium levels, affecting health negatively.* 01:22:53 *🛌 Melatonin synthesized from tryptophan may be compromised by glyphosate exposure, impacting sleep and overall health.* 01:23:23 *🧬 Methyl groups in melatonin can provide low-deuterium protons to mitochondria, aiding in repair and maintenance during sleep.* 01:24:06 *🔬 Complex cellular processes, such as cholesterol modification, can be understood through the lens of deuterium management within mitochondria.* 01:25:29 *🧬 Methyl groups in DNA and other molecules may have implications for overall health, as deuterium levels can affect cellular function.* 01:27:21 *🌿 Glyphosate can disrupt enzymes involved in methane production in gut bacteria, leading to methane toxicity and potential health issues.* 01:29:55 *💊 Synthetic supplements, including amino acids and B vitamins, may contain high deuterium levels, posing risks to health.* 01:31:15 *🔄 Some molecules, like trimethylamine oxide (TMAO), may accumulate due to synthetic choline intake, potentially indicating a deficiency in natural processes.* 01:36:07 *🥬 Glyphosate contamination in food and poor gut absorption can contribute to mineral deficiencies, impacting overall health.* 01:37:43 *🎙️ Dr. Seneff plans to re-upload an interview on cholesterol with Glen R. on his timeless insights.* 01:38:25 *🧩 Dr. Seneff acknowledges the complexity of the topics discussed and the challenge of understanding them fully.* 01:39:08 *🚥 Red and blue light influence deuterium behavior differently, with red light supporting proper behavior.* 01:40:16 *🌟 Dr. Seneff emphasizes the excitement of collaborative learning and how diverse perspectives contribute to a richer understanding of complex topics.* 01:41:52 *💡 Dr. Seneff expresses her commitment to sharing knowledge openly, contrasting with scientists who may keep ideas to themselves.* 01:42:33 *📚 Dr. Seneff advocates for accessible communication of scientific concepts and encourages self-education through reading papers and online resources.* Made with HARPA AI

@Thebusysuperhuman

Ай бұрын

Thank you

is this why my health went down hill once the pandemic forced me to no longer be able to afford grass fed beef? I've been stressed and gaining weight ever since I was forced to eat animals that probably contain glyphosate?

Is it common to get die reactions when starting durian depleted water? Every time I try and start drinking it I get bad symptoms. I have a lot of health issues prior to starting. I’m assuming that’s why?

@Thebusysuperhuman

3 күн бұрын

What concentration are you using ?

Does Glutathione detox deuterium?

@LTPottenger

Ай бұрын

no

Are dry fruits lower in deuterium as the water is largely gone? What a privilege to hear this conversation! Thank you.

@a.macdonald4877

2 ай бұрын

While dried fruits do lose water content during dehydration, their deuterium levels remain relatively unchanged. The process of dehydration does not significantly alter the deuterium content in dried fruits.

@brookstorm9789

2 ай бұрын

@@a.macdonald4877 That you for the clarification!

@Thebusysuperhuman

3 күн бұрын

No as there is far more deuterium is in the carbohydrates as they are a hydrated / deutarated carbons and people eat far more dried fruit than the fresh - as in most people eat one plum but 5-6 dates

So if I take 10 grams of proline daily, is that offsetting the deuterium I ingested? I’m having trouble getting through my head that I can afford deuterium depleted water.

@Thebusysuperhuman

Ай бұрын

I’d not spend your money on proline and there are lots of ways to deplete deuterium without the DDW

Dear Dr.s. What does a deuterium depleting diet look like? Thank you.

@Lukas-ye4wz

2 ай бұрын

www.ddcenters.com/wp-content/uploads/2019/03/dos-and-donts-of-deuterium-depletion.pdf

@debbiebeatty8449

2 ай бұрын

Keto/carnivore diets are lowest in deuterium, as Dr. Stephanie said, fats the lowest in D.

@brookstorm9789

2 ай бұрын

@@debbiebeatty8449 Thank you, Debbie.

@GenMEI-FM

2 ай бұрын

Keto or carnivore since those foods are lowest in deuterium. I recommend only locally grown produce in season which brings more cell coherency.

@brookstorm9789

2 ай бұрын

@@GenMEI-FM Thank you

The question about which method is best for testing D didn’t get answered.

@Thebusysuperhuman

2 ай бұрын

Do you mean deuterium? I’d use breath test

@debbiebeatty8449

2 ай бұрын

@@Thebusysuperhuman yes

@debbiebeatty8449

2 ай бұрын

The only test I’ve found is for saliva. Mine showed 139, I’ve eaten high fat carnivore for over a year. I then did about 6 weeks of Litewater, but haven’t retested.

Hello Deuterium depleting family! We meet again! 😄

@Thebusysuperhuman

Ай бұрын

The deuterium gang

How glyphosat impacts PCOS? 🤔 And what to do / How to lower homocysteine in your opinion without methyl folate ? I have 2 variants MTHFR.

@Thebusysuperhuman

2 ай бұрын

It’s related to sulphation as that’s needed to run the methylation & methionine cycle and sunlight is the best sulphator along with the gut microbiome

@Mo-yj3wf

2 ай бұрын

@@Thebusysuperhuman Thank you for your response. I need to add that I drink San Pellegrino having in mind sulphur and I did my labs in the end of June last year after lots of sunshine. Still my homocysteine level was 31… After years of zero supplements I have started adding them in November. Will check my labs soon again. Even though I know labs are not everything.

@OpenlyBritish

2 ай бұрын

@@Mo-yj3wf Try "Seeking Health" homocysteine supplement. And look up "Dirty Genes".

Thanks to Bart I found you!

@Thebusysuperhuman

Ай бұрын

Good old Bart !! Love him

@MikeWilliams17600

Ай бұрын

Same here!!

The only essential mineral the body doesn't conserve in the kidneys is Chromium.

@Thebusysuperhuman

28 күн бұрын

Yes !

If urine is one of the D depleting pathways, the would the urine D test not reflect this. Ie the test would be higher than the desired level in the body? Realising that D is different in different parts of the body. Where is the best average?

@Thebusysuperhuman

3 күн бұрын

Technically its best to get blood, urine, saliva and breath to fully understand - just thats too costly for the average joe

A summary with Practical Application would be very helpful here.

@Thebusysuperhuman

2 ай бұрын

Yes I offer things like this in my coaching group

Timestamps would be awesome.

I feel deuterium depleted trying to keep up with the discussion but facinating thank you.