Creatine: An overlooked Nootropic (Brain Supplement)? [Study 166 - 170 Analysis]
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0:00 - Introduction
1:14 - Topics Covered
2:38 - Mechanism of Action
13:49 - Creatine on Memory
13:57 - Study 166
21:22 - Age Effect
24:26 - Men & Women
27:06 - Mid-Point Conclusion
*******CRITIQUES, RULES, AND NOTES*******
Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:
The information provided in this study analysis is limited to the subject and outcomes detailed in the study analyzed [For example: “Consuming sugar (subject) raises insulin (outcome).”] and is not meant to be an all-encompassing education on every health outcome of the subject (unless otherwise stated). I welcome all respectful critique of the study as I may have missed a key detail that you may catch; if that is the case, I will make an ‘Amendment’ to the video and credit you (thank you for making science knowledge better!). Also be aware that I receive hundreds of KZread comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, KZread auto-deletes links, so I do not see most comments with links attached.
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#creatine #nootropic #brainhealth
Пікірлер: 193
*My creatine recommendation*: amzn.to/481gkrw *This is an affiliate link; however, I have no relationship with the brand and the supplement has been independently tested for purity.
@VeganLinked
10 ай бұрын
But the science doesn't support supplementing it for optimum cognitive health, right? Sure it "may" be helpful for people over 65 I think is what you were saying. But even still, which people (lifestyle behaviors) over 65? What happens with long-term supplementation? What about those who don't need it but take it, what happens to them? Any potential for negative synergistic effects with say other supplements? Why not just eat whole plant Foods? Those who have been in the field for like a half a century or longer and use to take the reductionist approach seem to be taking more of a wholistic approach these days (hose as in the many doctors and scientists that I follow and interview on my channel). Don't get me wrong, I care more about the science than people's opinions. I'm just trying to make sense of it all because it's very fascinating. And with so little evidence supporting supplementation I don't understand why you would recommend one. You do a great job explaining these mechanisms, theories and research! Thanks so much for all you do :-)
@Physionic
10 ай бұрын
I don't understand the first question? I'm stating here that it is a benefit for people over 65. As for lifestyle behaviors, I'd venture that the creatine effects are independent of other factors (except maybe diet). No one *needs* it, but it is a benefit if they take it. If they already generate enough creatine (which is a minority of people), they will only be wasting money, but it won't negatively affect their health. Vegans and vegetarians actually have the lowest endogenous creatine levels, so they'd be the *most* likely to want to supplement with it. Sure thing - thanks.
@pqmtlm
10 ай бұрын
Why you dont recommend creapure creatine? Since its the best provém quality creatine on the market? Tks 😊
@VeganLinked
10 ай бұрын
@@Physionic you stated it does not appear to be necessary and it "may" be necessary for people over 65. And which people exactly over-65?
@VeganLinked
10 ай бұрын
@@Physionic and for the sake of brevity Insanity when I use the word need I'm simply saying for optimum Healthspan it may be advantageous, since that's the assumed goal "need" seems sufficient. I understand people don't need things uggghhh
You are working towards Your PhD we know how valuable your time is thank you Nicolas.
Nerd away, Sir!!! At age 60, you've converted me into a fitness and nutrition NERD!!! Clearly, you’ve improved the quality of my life, and for that, I am genuinely grateful.
@Physionic
10 ай бұрын
I'm thrilled to hear it, John!
I do believe that you have discovered a new application for creatine being that it’s a nootropic for older people. Given its low cost, its positive effects on other aspects of physiology and general safe usage I would say that’s an important medical discovery. So basically creatine joins NAC and taurine as really useful supplements for older people. Really I’m grateful. I’m 61 so you might see why I’m so enthusiastic. Keep going!
@wilsont1010
10 ай бұрын
May have an effect on the kidneys. Do you think it's safe?
@MrBlaxjax
10 ай бұрын
@@wilsont1010 I have been taking creatine for a few months now. Not for its nootropic effects but for its general positives. Anyway I’m now reasonably healthy but I was diagnosed with chronic kidney disease a few years ago. My most recent urine tests show that both my albumin and my creatinine levels have fallen despite taking about 5 grams of creatine a day. The way I see it is that I have a strategy of trying to maintain good metabolic health. This involves cutting back on sugar and also starch, cutting down to two meals a day and doing some exercise. By doing this my blood pressure has fallen and certain other metrics such as h1ac, ALT, ldl and triglycerides have all moved in the right direction. So fairly recently about 3 months I have begun supplementing with glynac, creatine, taurine and collagen peptides and mainly because these supplements seem to be genuinely beneficial for slightly older folk and at the least they don’t seem to do any harm. I feel great by the way. In more direct answer to your question I’m of course concerned that creatine might be bad for kidney health because creatinine in serum and in urine is indicative of kidney disease. Regardless I haven’t yet had an upswing on those numbers so I reckon that at least for me because my weight and blood pressure have dropped my kidneys have started to work a bit better. I’ll only know for sure after my next blood test next summer. Mainly I’m hoping that my GFR remains stable or even improves. I’ll try to report back if I remember to.
@vinaykeesara8273
10 ай бұрын
How did you develop chronic kidney disease? Hypertension? Diabetes Mellitus?
@MrBlaxjax
10 ай бұрын
@@vinaykeesara8273 I don’t really know how I developed it. But I did suffer from high blood pressure so I assume it’s something to do with that. The reason for the diagnosis was that my GFR hit 50. That was a few years ago and since then my GFR has oscillated between 50 and 60. About a year and a bit ago my hba1c went to 42 which slotted me into pre-diabetic status. I was confused about being diagnosed pre diabetic as I don’t consume much sugar or sugary pop/fruit juice etc. Anyway long story short was that starchy food including some types of fruit was probably the villain. So I cut back on all that stuff. After a year I was no longer prediabetic and my blood pressure is down a lot. As for the kidney disease I still have that as it is chronic. But the main thing is that the old GFR remains stable. With a GFR between 50 and 60 it’s symptomless but any deterioration is clearly unwanted so I’m trying to keep a weather eye on bp, hba1c, alt and all that other metabolic stuff.
after I had covid I really felt that creatine helped my brain fog
@DDRHeretiC
10 ай бұрын
Caffeine, Bronkaid, Rx bars, RDL's helped me during covid. Creatine has been in the equation for years now. Used to be dirt cheap, most companies would just toss in a baggie of creatine monohydrate. Not anymore, heh.
@ldjt6184
10 ай бұрын
Do you take it on an empty stomach or with food?
@DDRHeretiC
10 ай бұрын
Normally with my morning meal. Chug water, eat meal with carbs. I sweat like I am on tren, so I drink a decent amount of water, esp with 7g or so of creatine daily.@@ldjt6184
@ChiefofPropaganda
10 ай бұрын
I've taken it daily when I lift since I was 17, I'm 25 now. I take it 30 minutes before gym on an empty stomach. I water fast for 24-48 hours weekly. I'm not sure if it being on an empty stomach could play a role or if fasting also helped but that may be possible. When I had covid I got it once and it was very brief. I've just heard a lot of family and friends say they had brain fog after covid for weeks but for me It only seemed like a couple days so it's possible it helped me@@ldjt6184
@wilsont1010
10 ай бұрын
Have you checked your kidneys before taking?
Great job teasing your Physionic Insiders membership. Since I discovered your videos a couple of months ago I’ve been watching them like crazy. I am completely sucked in, and loving the information. I almost always watch the whole videos, and occasionally watch them more than once. It is so rare to find real information from real studies, and trustworthy interpretation. I don’t have the skills to interpret the studies by reading them myself, and most you tubers are not trustworthy, so your presentations are great for me. Of course I want as much information as possible, and so after watching, I want more. I even bought your book on creatine. But sadly, I don’t think I can afford Insiders membership. You do so much work, and clearly you should be paid for it. So I think your Insiders membership is a great idea, it is just too expensive for me. So sad.
@Physionic
10 ай бұрын
Thank you - I'm humbled you'd go through the catalog with such determination. I appreciate it. Even if the Insiders isn't for you, you are welcome to join the free community - I post weekly articles, and they're entirely free. Would love to engage more!
@kenschulz4186
8 ай бұрын
@@Physionicthis is another amazing video! Thank you for shedding light. Just ordered my first batch of Monohydrate based on your recommendation and Rex from Attia. Quick question I had regarding MOA - where does the phosphate on phosphocreatine come from? Is that not also derived from ATP (delivered by creating kinase)? Or is there another source? Otherwise seems like a perpetual motion machine situation 😅 Thank you again for your great work!!!
Thank you for all your work and effort!!! It's well and truly appreciated!!! 🙏🙏🙏🙏🙏
@Physionic
10 ай бұрын
Thank you!
I used to like cat videos and what not, now im here learning nutrition.Its when the little details also get disected, meaning of acronyms help a lot. Al in all, instead of listening to some podcast where 2 people talk about their experience.. im actually getting an understanding of the mechanisms and a real look into scientific studies. This is a great place to be. Thank you for your time sir!
it's been helping tremulously with my cfs symptoms
Bro Can you make video about Mitigating Side Effects of NAC and safe dose for long term usage. Thanks for all your hardwork. Your videos have really changed my life for better.
@captainamericaamerica8090
10 ай бұрын
CAREFUL WITH CREATINE. IT PUT UNCLE IN' A,WHEELCHAIR.😩😩
@lindaabernathy4876
10 ай бұрын
@@captainamericaamerica8090 That deserves some clarification.
@milanpaudel9624
10 ай бұрын
may be his uncle was bedridden before ? idk @@terminator3728
@semiprolific774
10 ай бұрын
What are the side effects of NAC?
@471444a
10 ай бұрын
@@captainamericaamerica8090 Please don't fear monger. I'm very sorry for this happening to them, whatever caused it.
OMG I just purchased some of this today and now you are going me some more info. Thanks.
@davidespada01
10 ай бұрын
you can donate it
You do great work man, very little sensationalism and impressively non-biased, and very thorough..
I like you doing a preview of what the video contains. Love that.
Appropriate Creatine supplementation intuitively, for us older folks, seems plausible, as more and more research posits that more protein is needed for optimal health in our last decades. It definitely has piqued my interest for more investigation for the quality of life as one ages. What once was more easily retained in my younger years cognitively now takes more time to digest and ingest cognitively. I think many in the community would benefit from a thorough and ongoing breakdown as more research comes to fruition. Thanks, Nic....
Not a Doc yet but you have a great brain 🧠 👍🙋🏼♂️🇨🇦
@Physionic
10 ай бұрын
Thanks, Robert!
Thank You ! ⬆⬆
Skipping to conclusions?? Nah nah, this is a classroom, we cant skip the substance of the study 😊
Interesting - ATP is now an old friend. Thanks Nic.
81 years female I take it and the Taurine. Hope it all helps with osteoporosis.
@VeganLinked
10 ай бұрын
It's my understanding that exercise creates compound fractures in the bone that draw calcium in. And this is something you need to be doing throughout your life to protect later in life. And things like vitamin d (sunshine) and vitamin k (plants and bacteria) and even beta-carotene help protect against
@andresanchez728
10 ай бұрын
@@VeganLinked There is no K2 in plants (the type of vitamin k that deposits calcium into bones).
@betzib8021
10 ай бұрын
@@andresanchez728no but your body easily converts k1 to k2....eat greens
@jesincov
10 ай бұрын
@@andresanchez728 fermented soy beans have more mk7 than any other food.
@andresanchez728
10 ай бұрын
@@jesincov I am aware, but I don't know a single vegan that even knows what that is. People in the west do not eat fermented soy beans.
I would like to hear your analysis on anticholinergics and dementia, maybe include trazadone, not an anticholinergic, but is often used for insomnia. I recall reading trazodone may have neuroprotectant qualities.
@JacquesTreehorn
10 ай бұрын
I think anticholinergics make dementia worse. I have heard they also take years of of your life. I would like to hear more also. Thanks for asking.
@brianmcnary3960
3 ай бұрын
Ya that pill is a negative .
I really like the discussions of mechanisms of action with diagrams to really try to understand what is happening on the cellular level. Once you understand what is happening on the cellular level, then you can really understand what is happening to your body on a macro level.
@Physionic
10 ай бұрын
It's a huge reason I do these detailed analyses. I want to learn just as much as everyone else, and learning the intricacies of the mechanisms is wildly fascinating, and this is the only place we can really explore them in depth. Glad you enjoy them, too.
It would be great to see some sources for these studies, so one knows what to even critique
@Physionic
10 ай бұрын
They're listed, like always.
@maximegede1317
10 ай бұрын
@@Physionic alright, I had a second look and I found them!
I almost forgot to thumb this up.
HELLO , could you please discuss AGMATINE [agmatine sulphate] sometime. it is controversial, but we have known him for 100 years, he has a number of studies. now also new patents .. it has quite a broad-spectral effect. I would be interested in seeing this compound. Thank you, good luck and a relaxing and successful rest of the week:)"
Woah. Cool!
Hiii Nicholas could you maybe make a video about different types of scietific studies like meta analysis and others? What they are and how they are created? Or maybe give us some materials where we could learn about them? I dont relly know where i could learn this stuff, and i think i will need it in the future(studying molecular biology) Kind regards
I often wonder if creatine could have even more significant benefits for particular cohorts; Muscle atrophy Lung conditions - where physical exhaustion is more pronounced Dementia Injury recovery MS Parkinsons Post viral fatigue Depression Working in high activity roles or high stress environments, altitude etc Plus Vegan vs omnivores Western diet vs more wholefood/unprocessed diet Keto vs low fat High protein vs low protein
Mr. Future Doctor, I have a question on the amount to take per day and what it should be split up. According to our Lord and Savior, ChatGPT, most studies that include creatine use it at a 5 gram dosage. Is there a more defined dosage for those who also exercise? And should it be split up, aka morning and early evening? And any reason to believe that it may interfere with sleep? I probably can't take it at night. And in addition, should it be taken alone or with a protein shake or food to enhance uptake?
@user-iv9lr7uu3c
7 ай бұрын
I just take 1-2 grams a day. No need to do 4 grams like bodybuilders do.
How much water do we need to drink more when taking creative? I already drink around 2litres and I heard drinking more can be unhealthy if not enough electrolytes, but then you need more water with creatine
it works for me. 2 years on creatine, and now amino acid supplements, I'm going back to grad school...
Should individuals be cautious and contemplate potential disadvantages when using nootropics? Have you ever had any involvement with Normotim, such as experimentation or personal consumption?
I'm sipping on some deliciously gritty creatine as we speak. I believe I get marginally better at chess when I remember to keep up my creatine intake... probably placebo but still...
@Physionic
10 ай бұрын
Let's indulge our bias. ;)
@andy_ppp
10 ай бұрын
@@Physionic the placebo effect is real 🤘
@Mickju
10 ай бұрын
Creatine dissolves in warm/hot water.
@VeganLinked
10 ай бұрын
It seems like you're supplement would help you remember to take your supplement if your supplement was really working 😊
@winwinmilieudefensie7757
10 ай бұрын
@@VeganLinked😂
I am dealing with effects and symptoms from brain lesions, ultimately it may not be progressive but instead from a one-time event. Then the focus is on healing or compensating to recover pre-injury balance, cognition and stamina. Are there any studies that use brain injury, MS or other neurological damage to measure creatine’s potential to help these areas?
Not sure if anyone here can help. Just saw a Nutritionfacts vid on why vegetarians should take creatine to reduce homocystine levels. I asked the same question there, but I'll probably get a faster response here: I'm learning through trial and error that I have MTHFR mutation and should actually stay away from folates, or keep them as low as possible. If I understand correctly, if I up my intake of creatine (from the current 0 gms/day) then I should be able to tolerate folates slightly better?
Alright. I’ve listened to and enjoyed your content for a few months now. Please just tell me, what supplements and doses does a 62 year old man need? Looking forward to your next video.
0:00: 📚 Nicholas Veroven presents a detailed study analysis on the effects of creatine supplementation on memory and neurophysiological effects. 4:14: 🧠 Neurons rely on other cells called astrocytes to generate ATP from fats. 8:33: ⚡ The process of signal propagation and communication between neurons involves the exchange of sodium and potassium ions, which causes depolarization, repolarization, and hyperpolarization. 13:09: ⚡ Creatine increases energy availability in the brain, leading to improved neurophysiology function. 17:20: 📊 The researchers made a statistical error by including multiple measurements from the same sample, which artificially inflated the results of the analysis. 21:04: 🧠 There is no evidence of a significant effect of creatine supplementation on the brain. 25:27: 📊 The data analysis shows no effect in the combination of men and women, a possible trend towards an effect in women, and no effect in men specifically. Recap by Tammy AI
@Physionic
10 ай бұрын
Not bad, but missing a lot in this one. It did better on the shorter video recaps.
Do you have a video on working out fasted and if it produces more muscle growth? I’ve heard that working out fasted causes the body to produce HGH.
26:22 just to correct you on your stats, a large p value doesn't mean there is no effect, it just means that given the sample size, the effect may have been random. So it could mean the sample was too small. In the p value for women of .14, there's still a good 86% chance that the effect is real. Other than that I'm sold on creatine. Unlike vit b1, it doesn't lead to leaching of phosphorus, since the end metabolite creatinine is not phosphorylated.
@Physionic
10 ай бұрын
Technically speaking, you're right, Rene. Sometimes it's a bit difficult making sure to say the right words in the correct order all the time, but yes, the correct way to say it would be "there is a low statistical probability there is an effect", although, as you pointed out, one could argue 0.14 is pretty good.
The container I have says 1 tsp a day. What is the recommended daily dose for memory for 65 year olds?
So if we use the actual studies there is no effect?
@lynnwilliams5432
10 ай бұрын
Only there seems to be in the elderly so depending on your age in some studies….
My younger friends have christened my combo as "old man's crack" anecdotally I'm 20 years younger with my old iq Thankx Nic
@andresanchez728
10 ай бұрын
What's the combo?
I'm taking Creatine after leukemia, for both brain fog and body recovery.
@ivocanevo
8 ай бұрын
Nice to get a more expert analysis of the available data, thank you.
my neighbor has parkinsons, any ideas of what he can take ? Minerals ? Parkinson's to me seems to be the brain not receiving a full connection ( short circuit)
@Physionic
10 ай бұрын
Parkinsons is due to a lack of dopamine. I haven't looked into any therapies beyond the conventional, however. I hope to cover it one day.
@Taunt61
10 ай бұрын
Parkinson's happens when a part of the brain called substantia nigra degenerates. This part is responsible for movement and produces dopamine. There is no way to let it regenerate, once damaged it is damaged. Most widely used medication would be L-Dopa, which is the precursor to dopamine. Basically you try to raise the dopamine levels again. There is no supplementation that really solves the issue, since it is not about 'full connection' or short circuits, its literally brain damage, sometimes due to repeated trauma. We don't know why it exactly happens otherwise, but the neurodegeneration is correlated with protein misfolding in the neurons.
@adanbrown
10 ай бұрын
@@Physionic Please do! My father also has it, and I sure don't want this for my kids!
@VeganLinked
10 ай бұрын
@@adanbrownyikes maybe smoke cigarettes...
@leighwalton8190
25 күн бұрын
You could see Elliot Overton's interview with Parkinson's sufferer after taking high dose thiamine. :) @@Physionic
so...if i'm over 65 (70) male...what Kin/brand of Creatine do I take...how much...and when?
@dbozzi52
9 ай бұрын
Creapure seems to be the most investigated. I bought one of the bull brands on Amazon. It was very bitter. The creapure has almost no bitterness. Be careful what you buy . So much is imported from China and is not tested either here or there. Creapure is a patented form of it I believe. One brand that uses Creapure goes by the name of German Creatine.
Don't worry guys I've got a mulberry tree to keep me busy now
With regards to memory... I wonder if creatine would help with menopause induced brain fog?
@Physionic
10 ай бұрын
Maybe - depending on the mechanism.
Did I space out, or did you paywall the negative effects?
@Physionic
9 ай бұрын
I never paywall negative effects.
It is fairly pronounced that large amounts of creatine, over 10 grams a day, may not digest and irritate the stomach wall.
Hey daddy ❤
Is it advisable to take Creatine while on statins?
@wilsont1010
10 ай бұрын
Why are you on statin. The proper health marker is TRG/HDL. Statin will not reduce the risk of heart attack. It's probably time to change your doctor, dont throw your money away.
Important to purchase creatine manufactured in the USA. That said it is a very expensive supplement!
@VeganLinked
10 ай бұрын
And that's far seems like it's completely unnecessary like 99.999% of all other supplements on the market.
@pqmtlm
10 ай бұрын
Buy creapure creatine
@alanrobinson9021
3 ай бұрын
Your purchasing it from wrong cendor
caused bad bladder irritation
I would be interested in the neurological effect of creatine supplementation in vegans. They often develop peripheral neuropathy due to b12 deficiency, but could creatine deficiency also be playing a role here? Could it help those in the early stages of it?
@VeganLinked
10 ай бұрын
It doesn't seem likely since B12 seems to resolve the potential. People tend to get most of their B12 from fortified milk but for some reason the plant milks haven't been adding enough. But most people know to supplement this, including non-vegans as they lose intrinsic factor, including the farmers that give their livestock B12.
@andresanchez728
10 ай бұрын
@@VeganLinkedI have vegan relatives with neuropathy. The acute b12 deficiency is obviously the main driver, but that doesn't mean there is no effect from other deficiencies. And for vegans that neglected b12 and are now stuck with some degree of neuropathic pain, b12 is obviously not enough to improve the situation. Sure, it is likely that some of the damage simply cannot be reversed, but maybe some of it can? I know there is some talk among vegans of carnitinine for this, but perhaps creatine is another neuroprotective nutrient. If it helps mostly people over 65, that indicates it helps people deficient in it, and vegans consume zero creatine and only rely on their own body's production of it. I've also seen studies showing benefits of creatine for chemo induced neuropathy.
@bernardhurley6685
10 ай бұрын
How often do vegans develop peripheral neuropathy due to b12 deficiency? I have been a vegan for about 60 years, but my impression is that in the west it is rare to find anyone who has been a vegan for more than 10. From what I have read it is quite easy to get enough vitamin b12 from fermented soy products such as namyu. I personally only started taking b12 supplements when I could not get hold of them in the lockdown but have never had problems with peripheral neuropathy, or, at least, I don’t have the symptoms listed on the NHS web site. Of course, it could be something weird about me; as they say, the plural of anecdote is not data.
@VeganLinked
10 ай бұрын
@@bernardhurley6685 I have lots of long term vegans on my channel, even lifelong 72 years. And I have 75 interviews still to release many of which are lifelong and long term and I'm still interviewing many more. :) Plus other channels are like Gillian Berry and Plant Chompers both have lots and more to come. :)
@andresanchez728
10 ай бұрын
@@bernardhurley6685 Most vegans don't stay vegan long enough to develop it, but it is pretty much certain if you don't supplement. People say "well you can get this vitamin as a vegan by eating that one specific food" but the point is, most people are not that deliberate.
well that is a sad news
Kidney doctors urologist do not like creatine 😢.
@brianmcnary3960
3 ай бұрын
So it must actually be good for em ….Job security
It isn't overlooked. We already know
@ChiefofPropaganda
10 ай бұрын
it is overlooked lol
@user-ib9ky2jo9h
10 ай бұрын
@@ChiefofPropagandano no I know about it so therefore it’s not overlooked😂
@Physionic
10 ай бұрын
This should be easy to test: Let me ask you, does creatine improve executive function, composite memory, and complex attention?
@livsstilen
10 ай бұрын
@@user-ib9ky2jo9h You have to consider were you ARE. On a planet where most people reject things like evolution. To understand biology, you need to accept evolution.
@livsstilen
10 ай бұрын
@@user-ib9ky2jo9h Was I a bit self absorbed here🤣🤣
Seems that all nootropics just doesn't work in young and health people.
National Academy of Science report on Health and longevity recommends eating more veggies and fruits to protect against cognitive decline as you age. To add to that Nuts, Seeds, Fruits, Vegetables, Legumes, Seaweed, Pumpkin seeds, Soy beans, Peanuts, Chickpeas, Lentils, Watermelon seeds, etc can encourage the natural synthesis of creatine endogenously ❤
@Gainzster
10 ай бұрын
I.e. just eat
@HealthTruthMovement
10 ай бұрын
Good luck with that if you've got SIBO
@VeganLinked
10 ай бұрын
@@HealthTruthMovement what makes you think I would get SIBO? I have been doing this since 2011. Prior to that I was already moving in this direction since the 80's. And I know people who have been many decades longer than me some of their entire life and almost twice my age and zero SIBO, in fact no issues. Well, the only issue is being around sick non-vegans that don't care and are dropping like flies all around me...
@VeganLinked
10 ай бұрын
@@HealthTruthMovement so when is the sibo supposed to kick in exactly? After everyone around me who isn't vegan dies of cardio metabolic diseases, Cancers, and neurodegenerative disease? Well I guess I could add a few other things that aren't relevant to the list like fentanyl, alcohol and suicide...
@VeganLinked
10 ай бұрын
@@Gainzster just eat legumes, greens, grains, fruits, veggies, mushrooms, nuts, seeds, herbs and spices and a variety of each ❤️
What about creggatine?
@Physionic
10 ай бұрын
Sounds like a mutated version of creatine. Like creatine went through a radiation field and emerged... CREGGATINE.
So I have to be an “insider” to get dosing info? No thanks.
While I don't have any real substantive reason to distrust you, I still find the whole paywall thing unsettling. I get it, you should be paid for your hard work, and time spent doing this, but with the large preponderance of internet doctors and scientists being sellouts I'm sure you can understand my skepticism. From a layman's point of view any info gleamed from your services are no more trustworthy than those from other internet gurus. I don't have any way to know if you're misinterpreting data or not. Are there any experts in the field that can vouch for you, or am I limited to KZread comments and reviews of your book to see how credible you are? Again I don't mean any disrespect by this. I like the content I've seen of yours thus far, but I'm certainly no expert.
@Physionic
10 ай бұрын
Fair critique, Billy. I use a paywall, because I actively reject all other forms of monetization. For example, I've been contacted at least 500 times for sponsorship opportunities - some with massive companies (HelloFresh, Lumen, MacroFactor, and others), and I've rejected all of them outright, because I don't want to feel any sense of pressure that my analyses lead to positive spins so I can promote a product. I also refuse to create my own supplements for the same reason, even if I have control over the product. So, I'm self limiting my income (and trust me, as a student, I make very little) so that I can feel proud of the income I do allow myself (the Insiders, and a soon-to-release course). These sources of income are independent of if I end up claiming something is beneficial or not - people are signing up to get the analysis and the work, regardless of the outcome, which offers me freedom to be as honest as possible. That said, I have zero people that can vouch for me, and in the end, even if I had Dr. Superman and Superwoman vouching for me, would that make any difference? They're just human. This is exactly why my study analyses show the data, and explain how to read the data, so you can be presented with the data and make up your own mind - you don't have to go with my interpretation. I think that sets me apart from the rest, because instead of telling you, I'm showing you. If you don't trust me, that's A-OK, I respect you and your decision. Hopefully, in time, you'll get a sense of who I am and feel a bit more at ease (especially in moments that I mess up and have to walk back conclusions, because it should show I'm willing to course correct). Anyway, I hope that answers your questions and trepidations. I understand you not liking that I'm asking for money for the full version of my work, but unless I get some level of income, I seriously can't keep Physionic going (and certainly no hopes of growing it to release more, better content).
@Billy4321able
10 ай бұрын
I genuinely appreciate your transparency in your approach to content monetization. In the contemporary landscape, even those with the most steadfast principles often find themselves entangled with major sponsors. Your chosen payment model, aimed at preserving your editorial independence, is indeed a rational strategy, and I empathize with your perspective. However, I respectfully challenge your viewpoint regarding endorsements. It is worth noting that the broader segment of your audience, which includes non-experts, attributes significant value to both your analytical insights and your skillful articulation of complex concepts. While we may not find common ground on every issue, it is crucial to recognize that, just as we seek your expertise in elucidating intricate subjects, we also yearn for a sense of validation from other authorities within the field. Human fallibility is a universal truth, but it does not render all viewpoints equal in weight. It is conceivable that you might harbor the misconception that your audience predominantly comprises medical students, scientists, or doctors. I can assure you that this is not the case. Despite your occasional indulgence in biased speculation, you have never positioned yourself as an unwavering paragon of objectivity. Nevertheless, your audience places their trust in you. It is noteworthy that individuals with significantly loftier credentials may command less trust due to their association with contentious perspectives. As time progresses, it is highly probable that an increasing number of individuals will cite you as a dependable source. However, until you reach that point, it might be wise to reconsider the value proposition you offer to your audience. The current pricing point of $50 appears to establish an exclusive enclave, perhaps unintentionally alienating those who do not consider themselves as "true fans." Consequently, it could be construed as a departure from your customary content offerings. It is incumbent upon me to suggest that, until I have personally experienced your paid content, it remains somewhat enigmatic whether it serves as a platform for the presentation of imaginative yet unsubstantiated ideas. An adjustment in pricing could potentially bridge the divide, attracting a broader audience while mitigating any apprehensions about the nature of the content offered at this tier. That being said, I respect your decision either way and will likely continue to enjoy your KZread content for the foreseeable future. @@Physionic
@Physionic
10 ай бұрын
Thanks, Billy. I appreciate your feedback.
@user-bn5pq7bh5g
10 ай бұрын
It is too bad when people in comment section ask physionic 'what brand should I purchase.' It can put physionic in a akward situation. Thank you for the thorough study!
It’s sad, I can’t decide weather I want a head of hair or a more high functioning brain…
@WeighedWilson
10 ай бұрын
What makes you think it's linked to hair loss?
@andrewrivera4029
10 ай бұрын
@@WeighedWilson it’s said that creatine raises DHT which can contribute to hair lose in those genetically susceptible to hair lose. As a 57 year old guy who still has almost all of my hair with a father who started balding in his 30’s I consider myself lucky that I still have hair and am reasonably fit I’m debating weather I need creatine. I supplement with fish oil, berberine, vitamin E among other vitamins and do a KETO diet mostly to reduce inflammation from sugar/carbs as it’s said dementia/Alzheimer’s is just type 3 diabetes.
@WeighedWilson
10 ай бұрын
I've heard it said in comment sections too. I've never seen anyone reference a study to validate the claim. There's approximately 500mg of creatine in a 112 gram (4oz) serving of beef.
@andrewrivera4029
10 ай бұрын
@@WeighedWilson then why supplement? Just eat beef.
@WeighedWilson
10 ай бұрын
@@andrewrivera4029 2.5 pounds of beef a day to get to 5mg is why. Maybe supplementing is only beneficial for vegetarians? Or maybe you benefit from more than we normally would consume.
I am not a fan of one compound will make huge difference Health wise. Simply because there is tons of factors that get into play that neglect the benefits of that compound. Usually the person promoting a compound has something to sell like a supplement or a book
@Physionic
10 ай бұрын
Fair enough. You don't have to take advantage of it if you prefer not.
@AceKinG2024
10 ай бұрын
@@Physionic I take it but I make sure the other factors are addressed first.
CAREFUL! CREATINE' HAS SIDE EFFECTS TOO. ALL MAJOR CHEMS. DO. MY UNCLE IS ON' DIALYSIS! BECAUSE of CREATINE😓😓
@Physionic
10 ай бұрын
If this is true, your uncle more than likely had poor kidney health and then took creatine (which is contraindicated) - there are many studies indicating creatine safety, including for people with healthy kidneys.
@captainamericaamerica8090
10 ай бұрын
@@Physionic My uncle was in perfect health, HIS ORGANS FUNCTIONED PERFECTLY!! BEFORE HIM TAKING THE RECOM. DOSE DAILY OF CREATINE. THERE'S ALSO WITHDRAW SYMPTOMS TOO, WITH CREATINE.
@Battery-kf4vu
10 ай бұрын
@@Physionic I put my mother on 3-4g creatine, her GFR went from 58 to 45 in one month. It came back up when she stopped. I noticed my GFR went down by about 3, from 100 to 97 something like that at 1-2g/day.
@Physionic
10 ай бұрын
Fair enough, Battery, but like I said, it's fine for anyone with healthy kidneys and contraindicated for anyone with struggling kidneys (a GFR of 58 is far below normal). Additionally, did you only add creatine or did you make any other changes between the first measure and the second?
@captainamericaamerica8090
10 ай бұрын
@@Physionic It was exams by several specialists. It was the creatine!
Don't worry guys I've got a mulberry tree to keep me busy now