*My recommendation for Taurine* * : amzn.to/3JZx08n AMENDMENT: I believe I mention that taurine is an amino acid (true) that can be used in functional proteins - this last part is incorrect; taurine is an amino acid, but it not involved incorporated in proteins through protein synthesis. Also, on a quick search (I haven’t looked into this deeply), taurine seems to reduce or attenuate increases in cholesterol lipoproteins according to a meta-analysis (DOI: 10.1016/j.ejphar.2020.173533). So, as I suspected, it isn’t much of a worry (I’ll need to confirm this) - some people in the comments of my last video on this topic suggested that taurine levels may be elevated in people who consume more meat (saturated fat), which could have an indirect effect on lipoprotein levels. This is a good possibility. *This has been independently lab tested for purity and contaminants; additionally, this is an affiliate link, but I have no relationship with the brand.

@SamsonFernendez

Жыл бұрын

At your convenience of course :) Would you mind talking about nutrient synergies and how to do it in a whole foods manner instead of through supplementation? Not that I'm against supplementation, but just that eating common foods seems easier than picking out high quality supplements and keeping track of dosage and price changes between brands and variations.. Also it's a bit easier when eating animals because most nutrients are passed down from the animal's diet into ours, so would be great if you could help with non-animal based combinations for good/ideal nutrient synergies :) Thanks loads in advance :)

@Danny-mg1hu

Жыл бұрын

ah yeah! this is what i was looking for!!!

@artemisliontas4748

Жыл бұрын

Quick question for you if you don't mind In your opinion can Taurine help with reducing inflammation that is caused by psoriatic arthritis and hyperthyroidism?

@danwylie-sears1134

Жыл бұрын

Thank you for including the correction that taurine is not one of the amino acids used in protein synthesis. I scrolled down to comments as soon as I heard the error. "Sapiens" as our specific epithet is a Latin adjective in nominative singular form, not an English noun in plural form. There is no such thing as "a Homo sapien".

@susymay7831

Жыл бұрын

Are you taking taurine yourself?

Thank you for not adding stupid background "music". Please let your channel clean. It is the important message I want to hear. ❤ your education.

My great, great, great, great grandkids will ask me if I’m on taurine 😊

@Physionic

Жыл бұрын

Hahaha! And you'll jump out of bed with your newly acquired bionic legs and say, "Kids, let's go dunk a basketball."

@jmc8076

Жыл бұрын

Great attitude. Hope it happens. ✌️

@wheelofcheese100

Жыл бұрын

@@jmc8076 🙂

@tobiaskevorkazito4072

Жыл бұрын

🙏🌸😂

@rogerbritus9378

Жыл бұрын

By then that will be old news.

Excellent vlog. I've been taking Taurine for six months and at 64 I'm feeling the benefits. But the best thing I found it useful for is my 8 year old Dog whose epilepsy has returned after 2 years on a medication called Epiphen. The seizures started back in August and as I keep a seizure journal I could see how these seizures have come back gradually until December from the 1st up until the 14th she suffered 16 seizures. After hearing it helps with brain dysfunction and is ok for dogs I gave my dog a dose and since the 15th December she hasn't had 1 single seizure. I have documented this and done a KZread vlog confirming how it has helped her and I'm doing weekly updates. Unlike the Epiphen the Taurine may even extend her life and it's beneficial for her overall health which is more than I can say for the Epiphen. Anyone wishing to hear the progress on my findings can see it for themselves on my KZread channel (Just Kidding) yes that's the name of it.

Thank you for NOT shortening your videos. I understand we are all pressed for time in this world with work, family's, and social media. Knowledge should not be sacrificed to accommodate a schedule. I feel we should make the time to properly absorb and digest the material. You teach a lot of topics and the depth you cover is important. More importantly is your clear explanation of the material. Please don't change a thing and continue doing what you do!!🙏

@jonny9finger

5 ай бұрын

Absolutely I've learnt so much from this man with great data supports the theory. Last 5 months my energy level went thru the roof with his advice.

I’ve been taking taurine the last month I’m 60 and I feel as fit now as I did when I was younger It’s amazing 🥊

@tiz6549

8 күн бұрын

How much are you taking?

First time on your channel. You explained everything methodically and clearly for the average person to understand. Great job!

@Physionic

10 ай бұрын

That's kind of you to say - thank you.

My, my, my, how time flies. I remember Pearson and Shaw talking about taurine back in the 80s, saying that someday this would be the new vitamin C. I have been using taurine that long, and what was an inexpensive nutrient will turn into the new darling, become scarce, and go up in price. The dark side to these studies. The GlyNac study did the same thing.

@jackbuaer3828

Жыл бұрын

If Durk Pearson looked like he was in 20s ,30s, 40s or 50s, I might say that he is on to something that turns back the clock. Based upon visual appearance (and that counts for a lot in my book), his regimen, if effective at all, would be modest at best. People are quick to discount visual appearance as a marker of aging, but it typically and readily easily allows us to distinguish between young and old (if no cosmetic procedures). There is no doubt about this. A 50 year old looks way different than a 20 year old. If one could truly slow aging, they're likely going to slow the visual markers as well blood and other biomarkers.

@midnightsnack1306

Жыл бұрын

@@jackbuaer3828I’m sure a lot of aging folks would certainly want to look like they are in their twenties forever but for people me I just want to be strong and healthy enough that I can still play tag with my grandchildren when the day comes.

@birage9885

Жыл бұрын

@@jackbuaer3828 Ha, ha, I can't argue that about their appearance. However, I think P&S did other things that sabotaged their ability to age slowly. Of course, at the time, science was limited on nutrient intervention, etc. Finally, if you use that as a determining factor to validate the study on taurine, it looks like taurine isn't as good as they are saying, lol.

@jackbuaer3828

Жыл бұрын

@@birage9885 I want to clarify that I was in no way meaning to denigrate their appearance. I was only trying to say that they look their age. There is nothing wrong with that. Most people look their age or worse. I was also trying to make the point that it is likel difficult to biohack aging through extreme efforts. So far I am not aware of a miraculous regimen or supplement that reduces the visual impact of aging. We see some Asian people that look much younger than their age, but many of them are not following a single regimen. If at some point we get a miracle pill or miracle regimen, I expect it will cause "across the board" improvements visual appearances among those over 50 presuming that have started the pill or regimen in their late 20s, 30s or 40s. Some people that look much younger than their age in their mid 50s or early 60s claim to do nothing out of the ordinary.

@damien2198

Жыл бұрын

@@jackbuaer3828 " I was only trying to say that they look their age" They were looking awful for their age

Awesome you are doing this, finally good scientific videos. I have a physics background and really appreciate the time and effort you put in this. We need more people like you!!

@Physionic

11 ай бұрын

Thanks, Michael!

Thanks to Physionic I'll be an amateur molecular medicine scientist soon. Mom will be so proud of me 😃

@theantiqueactionfigure

Жыл бұрын

Have you started your KZread channel yet? ❤ 😂

@BakamonNO

Жыл бұрын

@@theantiqueactionfigure lol. No I'm not as charming as Physionic. Maybe in another life😅

@Amandaetutor

11 ай бұрын

A new skill

@Amandaetutor

11 ай бұрын

That’s how I started 30 years ago - I now include all this in my regular teaching - they love it And it keeps me interested

Only few min in and gave thumbs up just on quality of research and effort to organize data and facts for viewers. Brilliant. Thx Nic.

@Physionic

Жыл бұрын

Thanks, jmc!

I knew an old guy, thin as a rake and he was always chugging Monster energy drinks. I have to admit to being worried for the guy. Little did I know that he was immortal.

@garyssimo

Жыл бұрын

33 grams sjger per 8 ounces will ruin his health.

@transkryption

Жыл бұрын

@@garyssimo sjger is that the new street drug from Prague? or is that cake?

@user-fy7ri8gu8l

Жыл бұрын

@@garyssimo Not really. Compared to what? What is his TDI for sugar? How active is he? 33g is basically jack shit for moderately active people that work out and do cardio during the week. It's a lot for S.A.D. metabolic disorder having American couch potatoes that are the problem. A person with a healthy metabolism really needs 60-90g per hour of zone two work out alone, a can of this will do nothing to them, American couch potato will need to shoot themselves with insulin just looking at it.

@kathybrown8533

Жыл бұрын

recommended dosing for a 65 year old active female

@kathybrown8533

Жыл бұрын

can this supplement help someone w/ cancer?

Day 2 on 2000mg Taurine. 59 year old male overweight with high blood pressure. I do lift weights three days a week and walk a little most days. I also take Creatine which has been very helpful in the gym. Hoping to see good results with Taurine. Thank you for the very informative video.

When I was in college, molecular biology was a NEW major! That was a lifetime ago, and though I eventually wound up in computer science as a career, I still love to hear "trash" talk from biology people. I'm also interested in it because I'm getting old and looking for the Fountain of Youth. I've been taking Taurine for about 3 months now, but haven't yet noticed any significant changes. I'm thinking about increasing my dosage. Thanks for this and good luck with your studies.

@glenntimberlake2413

Ай бұрын

How much do you take? With food? Or before food?

By far the best channel I've found for indepth explanation of studies. Thank you so much for taking the time.

@Physionic

10 ай бұрын

Thanks, Jenna!

This was a great breakdown of this study and you covered it well, and you put it into layman terms that we can all understand. You provide good evidence and as a 64 year old with a deteriorating spinal condition I found it encouraging and have now included Taurine into my diet. I have in the past 5 years made many changes in how I look after myself and the first thing I did was to stop smoking, then I worked on my weight and completely changed my diet and have been a pestcaterian for 2 years, I have gone from 18.4 stone down to 13 stone and I have a daily exercise routine. I include kefir in my diet as I understand the importance of gut health. I have managed to come off all my medications which there were many including Statins and blood pressure medication, and this vlog has convinced me that this is really an essential supplement that all over 50s should consider. Thank you for this breakdown on Taurine I found it encouraging. Great channel you're a good man. Thank you, Thank you.

I'm watching this particular video for the third time to glean the maximum amount of information contained herein. I am a classically trained epidemiologist and tend to dismiss...or outright laugh at...most medical channels here on RubeTube. You have a winner and a subscriber.

@Physionic

11 ай бұрын

Thank you!

I’m so glad you didn’t shorten the video. Every second was time well spent. When I saw the length of it I thought I should just watch the intro and then listen to the rest during my daily walk. Once I started watching, I couldn’t stop. The visual information you provided was essential in helping me understand everything you said. Thank you for the time you spent creating this video.

Excellent work! Appreciate the time stamps for future reference.

Thank you for not shortening these videos ❤️

I have taken 7 grams of taurine for over 7 years to renew my lungs from smoking. I can now run without any issues, wheezing is gone, no more trouble feeling like I'm not getting enough air. I still smoke when I'm having cocktails. No apparent side effects.i suppose I should add that it has been 7 grams (7000mg) a day

@tullyapx500

Жыл бұрын

I quit smoking after 42 yrs of smoking. I didnt take anything, but I run regularly and only had wheezing and out of breath issues when I started running. I have no obvious ill effects from smoking. All we can offer is our own anecdotal evidence, and both ours have the same outcome with or without taurine.

@supernice_auto

Жыл бұрын

you should just quit smoking- it's disgusting

@rogerbritus9378

Жыл бұрын

​@@tullyapx500You don't say how long ago you quit. Give it some time and a different result could appear. Make sure you test your lungs frequently for abnormal growths!

@pjaworek6793

Жыл бұрын

Interesting comments guys. Nick should do a video on respiratory issues. So much going on from alcohol effects on lungs, evali, covid, supplements like NAC, nmn, vitamins/minerals, omega3, ginseng, and now taurine.

@Utoko

Жыл бұрын

Good for you! but anecdotes can be misleading and throw you of the fast of truth seeking fast. You could share where you based your assumption that it would renew your lungs on.

Dr. Verhoeven, thank you for your work here. I've been supplementing taurine for about 10 years now, buying it in bulk packages of 1 kg and mixing it in drinking water in gallon jugs, with large quantities of MSM. My daily dosage is about 2.5 g of taurine. I started doing this only for this one reason: I had read that in places like Japan, where people are famous for their longevity, one of the isolated factors for this was that their diet was high in taurine. I didn't really learn much of the details until I saw your work. But there is one thing that troubles me. I also powerlift regularly, so building and retaining muscle mass is a priority for me. And apparently, taurine supplementation short-circuits the end of the mTOR pathway. I know there are several paths to activate mTOR, but apparently taurine suppresses the very end stage, of this special protein that is responsible for stimulating muscle protein synthesis, so it appears that regardless which way you approach mTOR, taurine suppresses muscle protein synthesis. There are several known compounds that do this, that are all associated with longevity and anti-aging: rapamycin (whence comes the name "mechanistic target of rapamycin" or "mTOR"), resveratrol, epi-gallo catechin gallate, etc. All are known for improving longevity, but suppressing mTOR. Apparently taurine supplementation has the same exact effect: it improves your longevity generally, by delaying cell senescence and the subsequent buildup of "zombie" cells, but it also suppresses the buildup of muscle mass. If this is right, it's very disappointing: if I want to retain muscle mass, I have to live with the normal aging pathways. If I want to delay aging, I have to live with my powerlifting not yielding one of the most desirable rewards of that work. Do you know of any way to get around this?

@rubensonorio8805

11 ай бұрын

Thanks for sharing 😅

@jac6541

11 ай бұрын

I’m very interested in the answers to this.

@justdave1

11 ай бұрын

If someone has a workaround, I'd like to see it myself. Until then the best path may be one of lowered expectations. It seems like living longer has more benefit. I suspect you have a lot of muscle allready, more than enough to take you comfortably into older age. I'm 72 and weak as a kitten, which I am fighting (with myself) to change. I've lost 80 pounds and time to work on some muscles. I need some but not really that much. I think Taurine will help me in general and not interfer with normal body building or shaping. If your one of the powerbuilding elite then your needs are specialized, I'd ask a professional somebody for advice.

@Lulu-kt6gr

11 ай бұрын

Is it a significant amount of suppression? Meaning, would it keep a person from gaining bulk or would it keep the muscle from growing at all? As a woman I’m only interested in maintaining firm muscles that are also strong

@miriaml.150

11 ай бұрын

In regard to the dose you are supplementing with for taurine you may need to pull back. There's something called a hormetic effect. That means that something is more effective taken in a smaller amount and can actually harmful taken in a larger amount. I would investigate that as a pertains to taurine. (Dietitian since 1982)

The algorithm is lagging i love this type of content and have never heard of you until now. I started dabbling with taurine 20 years ago when i was an idiot that took clen to get summer lean and heard Taurine prevents clen muscle cramps. The cramps were for real. Taurine seemed to help. I forgot about Taurine until a few years ago when i heard it helped with bile so i took it when i noticed digestive issues. Cut to a year later i read that taurine helps with anxiety by converting glutamate to GABA and potentially by reducing blood pressure which is part of the anxiety cycle ; feeling physiologically excited (heart rate hot face) thinking others notice this which is furthering nervousness. Anyways i had always been someone who lived with anxiety like literally sweating if someone i didnt know well was close to me talking to me for long enough to elicit this response. But i noticed as i read about this plausible taurine mechanism that i had not gotten that anxiousness since regularly taking taurine. So theres that. It also helped my sleep onset which used to take hours sometimes likely from anxiety over thinking when trying to sleep and taurine seems to just calm the mind it's amazing for so many things.

Great content as always!!

That's absolutely great channel! Thank you so much for your work

I'm just so into these lectures of yours, Verhoeven. As a neurologist, all this is so fascinating to me. Immeasurably more fun than allopathic medicine.

So glad I found your channel this is extremely interesting. Thank you!

A gastrointestinal transit test is a diagnostic procedure used to assess the movement of food and waste through the digestive system. It is often employed to diagnose conditions such as constipation or gastrointestinal motility disorders. The test involves tracking the passage of a substance (such as a radioactive marker or a capsule containing markers) through the digestive tract. The transit time is then measured to evaluate the function of the digestive system. To detect an improvement in a gastrointestinal transit test, you would typically look for a decrease in transit time. A faster Transit Time: If the transit time of the substance through the digestive tract decreases, it suggests that the motility of the gastrointestinal system has improved. This can be an indication of improved muscle contractions and coordination in the digestive organs. Good guess Nicolas!

Incredible work you put in - thank you!!

Historical I’ve been skeptical of taurine supplementation, but this new research has my interest. Excellent review of this research 👏🏾

@EdT.-xt6yv

7 ай бұрын

Don't forget exercise & eating greens ,,,

Don't shorten your videos. Wonderful lecture.

Mightily impressed Dr. Sahb. Im your newest subscriber

really awesome video man, i really appreciate your work.

Please never stop making videos!! I just found you today & took my 1st Taurine!! (60)....Love how you take your time and break it down !!the longer the video the better!!!♥️

Thanks for a great video. I really like the detailed, longer format.

@Physionic

11 ай бұрын

Thanks, Andrew.

You have the most unusual talent to explain things very clearly, I am so glad I found you , I hope you expand your repertoire! 😍😍😍😍😍

Wow, Excellent presentation. I thank you for taking the time to put this together. Incredible information.

Love this hardcore science. Excellent job explaining, and so patient with us! Thank you!

You rock, Nick. Thank you. Your breakdown is perfect. As a newbee, I am looking forward to the rest of your content. No more researching for me. cheers champ.🏆

@Physionic

11 ай бұрын

Thank you, Peter.

Great video!! And it is great that you stay away from advertisments

awesome video, love the details you go into, keep your videos long!

@Physionic

8 ай бұрын

Thanks, Cory

Thank you I love this wonderful video! We appreciate the Information!

I appreciate the detailed videos. I appreciate your hard work. Making it understandable for the regular guy. Thanks.

@MyLove-uj8zi

11 ай бұрын

Or gal..lol.

@Physionic

11 ай бұрын

My pleasure - a labor of love.

I love love love you as my KZread professor!!!

Yes, it's VERY important to follow LDL/HDL results using Taurine in further videos.

@petermalmgren1207

Жыл бұрын

Ok

Started taking taurine and creatine because of you in depth reporting. Looking at glynac. I see you are somewhat ambivalent about glynac. Back ground, 74 yr old, went from sissy squats to 280/300 pound 3 set/20 rep squats. Thanks for all your help in understanding supplements.

You are my favorite KZreadr! ✨️

Nick so happy to hear you say “to be FRANK with you” instead of ‘to be honest’…!

Excellent info, thanks! Btw, bone mass matters way before 80 yo. Women start losing bone density in their 50's or even earlier.

@theantiqueactionfigure

Жыл бұрын

They don't test men for bone density until it's too late. Don't ask me how I know!

@johna5484

11 ай бұрын

@@theantiqueactionfigureI’m a man and started getting tested in my 40’s. You have to ask. You are your own health advocate. Nobody else really cares about your health .

@Hack3r91

11 ай бұрын

Bone density peaks in your 20s, starts declining in your 30s and plummets from your 40s onwards

@bencyber8595

9 ай бұрын

yes, true

@TheMommom8

9 ай бұрын

Excellent presentation! A question..I normally always have a low white blood count , do you think taurine supplementation would be a problem? Thank you for all the time and work you invest in these podcasts!

Thank you for this video. You a a brilliant man. Very interesting video

I listen to your information while doing a work out at my gym! Not a problem!!😊

Fascinating research! If I understand this correctly, Taurine has so many benefits except for muscle development where it can be a negative side affect if trying to build muscle. If that is correct, then no elders should take this. I'm 71, petite, female and have been supplementing a 1000 MG. I feel like I have lost muscle not gained, even though I lift heavy weights. A clarification would be appreciated. Thank you, Nick, I love your videos and learn so much from you. PS: and you sure are easy on the eyes. 😊

@lovemissle

10 ай бұрын

Oh noooo😢. I just ordered a bottle from Amazon. 1000mg is that what I should take?

@lighthealerastrid1465

8 ай бұрын

@@lovemissle Oops so did I… the powder. Also 71 like Kathy and enjoying muscle hypertrophy.

@kiranbala90

6 ай бұрын

Powder is cheaper to buy than capsules.

@paulharrisonadventuregearm5457

3 ай бұрын

Taurine is fine for muscle development.

@paulharrisonadventuregearm5457

3 ай бұрын

​@@lighthealerastrid1465dhea is your answer among a range of vitamins. In females a tiny amount of dhea is highly anabolic in older females

Thank you so much for all the knowledge

Excellent presentation!

I am 51 and take Taurin 2 grams daily for 6 months. My sleep got better, my mood is like more balanced and i have more energy keeping low heard pace. I don‘ t know the reason, but my doktor seing my blood work, regading my LDL cholesterol asked me if i take any medicine. After my negative answer he said, that he has never seen so low cholesterol lebels on individual with my age without taking any pills. Regards

@Mikolas649

Ай бұрын

Low TC And low LDL, contraindicated for longevity, despite what centralized doctors tell you

@hfctab3799

24 күн бұрын

Not so, can be the sign of efficient hormone activity. As high cholesterol is one of the signs of low thyroid function

Wonderful review.A good format .

@Physionic

Жыл бұрын

Thank you, David.

Thank you for this informative video, very interesting.

L Taurine is the compliment of glutamine. If you are sensitive to MSG taking L Taurine can balance out MSG when you feel you have ingested too much of it. MSG is slathered into so many processed foods, even under different names. Truth in labeling is an org that is educational on how much MSG people are actually eating under different labeling.

From a fan of orthomolecular medicine I love this delivery info.

Cool work, your love subject is obvious and somewhat contagious

Optimal dosing information should offered in the public segment.

@smarzig

3 ай бұрын

Left out purposely

Absolute reliable information. Top grade tour. thanks!

Great video. Extremely interesting.

Love your channel and your information dissemination

Good info brother... Thankyou for the effort!!!!

Great content as always👍

No need to shorten!!! Perfect concept!! Not average

Just found your channel. Fantastic breakdown, Nick. 👍👍👍 Subscribed!

@Physionic

4 ай бұрын

Thanks, Laura :)

This is brilliant. Thank you

@Physionic

Жыл бұрын

Thank you!

Great topic, my interest is so piqued 🙏🌸

I'd love to see a video on Thiamine- there are a lot of claims of it's health benefits in high doses and the different forms of it. Specifically TTFD and benfotamine.

@amylee9

11 ай бұрын

It helped my young son improve his stutter significantly. The effects would wear out but I would just supplement again while also trying other methods. He’s now a teen and no longer stutters.

@Bazza5000

11 ай бұрын

I hear a lot of people talking about that stuff, but don't know much about it. I am desperate to heal my gut health.

@brainwithani5693

9 ай бұрын

@@Bazza5000 check out Elliot Overton

@brainwithani5693

9 ай бұрын

@@amylee9 wow that's great!

@jenniferboehm514

2 ай бұрын

Benfotamine helped tremendously for my essential tremor for about a month. For some unknown reason, it stopped working. Frustrating. Finding that sweet spot of dosing has been difficult.

Taurine is used greatly by the brain> GABA, the heart and the thyroid. I have been rx taurine for dysfunctional thyroid and elevated LDLs, anxiety…ETC for years. Scientific publications have documented all the above-- years ago. When it makes it to MSM/textbooks etc, it is 5-10 yrs old info if not older.

@lostinthoughts5645

9 ай бұрын

So did you manage to significantly reduce anxiety and is your thyroid ok now? May I ask what is your dosage? Thx!

@Bellasafari

9 ай бұрын

@@lostinthoughts5645 I am a doctor that prescribes it for these issues. Yes it works along with much other support. Dose is dependent…

I am age 81, never smoked or used alcohol and exercise regularly but I am feeling weaker so I will seek source and dose of Taurine immediately.😅

@jerryboucher8557

11 ай бұрын

Try Super B Complex and Magnesium

@RobReadControlledProjects

10 ай бұрын

You might look into Creatine and Berberine too...

Excellent! Many thanks for sharing

It is pleasure to listen to your lectures.

Please do not shorten the vids. I want ALL the data. Thx Nic.

I found this on Immunophenotyping, hope this helps. Immunophenotyping detects the presence or absence of white blood cell (WBC) antigens. These antigens are protein structures found on the surface or interior of WBCs. Typical groupings of antigens are present on normal WBCs. Atypical but characteristic groupings are seen with specific leukaemias and lymphomas. This allows immunophenotyping to be useful in helping to diagnose and classify these blood cell cancers dependent on the particular pattern of antigens present or absent.

Amazing info by a well spoken man

16:35. Over time we shrink. Hay, I was a tad taller than 6 feet in high school now that I’m 45 in a tad taller than 5’ 11”. I have back issues now. So, that degenerative joint disease is real. All you younger people take care of yourself. Your older version of yourself will thank you for it

Thank you for not making your videos shorter 🎉

I am so interested in your video-release and consider them to be delivered at an assimilable/laymen's pace. This topic is of great interest to me because, prior to your productions, I have only met with derogatory feedback about this supplement. Looking forward to gaining more knowledge through your releases.

Good timestamps!❤❤❤❤❤

Thank you. Very clear explanation.

This is the most thorough treatment I've seen here. I am considering supplementation, but wary of the sedative effects. Some report lethargy with taurine supplementation. I had a horrible experience with choline. Even taking a small amount of choline made moderately challenging tasks herculean.

@criticalbil1

11 ай бұрын

Choline didn't seem to do anything for me either, including soy lecithin and DMAE. Taurine is intriguing me though.

Loved it and thank you👍👍🙏

Awesome presentation! You answered many of the questions I had as I've been taking Taurine for awhile now. Can you do a presentation on vitamins D3and K2 with respect to the circulatory system?

He does the most entertaining research reports.

This individual has the discipline and the intelligence to be a scientist.

Great video! Can you go next level breakdown on oxalates? And then the link - bad link - between it and curcumin, which was a bummer to hear from a great oxalates doc video on YT. That's me asking. Who the hell am I to ask? I don't know, I'm just asking, you don't have to get pissy about it. A nod to your humor, which is awesome!

Always learn something from you. I’m taking it now been about five days.

Nope no shortenings, much much too important what we can learn and whst you've to say..thanx and greetings from Switzerland - Isa 🤩

Thank you for making this content physionic

@Physionic

Жыл бұрын

Thanks for watching, Gary. :)

Great timing! Just finished watching the first taurine video

A critical take regarding supplementation in humans from Peter Attia: "A critical variable largely ignored by the study authors is precisely why taurine levels decrease with age. Given that endogenous taurine synthesis is so low in humans, circulating taurine is determined by a balance of absorption from diet and excretion (primarily in urine). This leaves us with three (non-mutually exclusive) possible reasons for the apparent decline with age: 1) a reduction in dietary intake; 2) a reduction in rates of intestinal absorption of taurine from food; or 3) an increase in the rate of taurine excretion. No nutritional data have ever indicated that people consume less meat and seafood at age 60 than they do as kids, so we can exclude possibility #1. Possibility #2 would suggest that we need to consume more taurine as adults than we do as children in order to absorb the same amount, which in turn might mean that supplementation would boost circulating levels and help mitigate their age-related decline. Possibility #3, on the other hand, would mean that supplementation would have very little effect on circulating taurine. So which is it? We don’t currently know and have no direct data to address this question, but the pieces of evidence we have make the best case for possibility #3. Taurine reabsorption in the kidneys - a process that returns taurine to circulation and prevents its excretion - requires co-transport with sodium ions moving down their chemical gradient (i.e., from high extracellular concentration to low intracellular concentration), an energetically favorable process which helps to drive taurine transport forward. But with age, renal ability to maintain electrolyte gradients gradually deteriorates, contributing to the well-documented age-related decline in kidney function. Thus, it seems likely that the capacity to reabsorb taurine from urine also falls over time, resulting in increased excretion. This possibility is further supported by the observation that, regardless of age, taurine levels are typically low in the presence of chronic kidney disease. Why is supplementation unlikely to help most individuals? In general, amino acids can filter into urine, but most are reabsorbed by the kidneys at rates of ~98-99%, meaning that very little is actually excreted. Taurine is different in that it is only reabsorbed at a high level when circulating levels are low. When dietary intake and circulating levels are high, taurine reabsorption rates can be as low as 20%, resulting in a high level of excretion. On the other side of the equation, rates of taurine absorption from the gut decrease with increasing circulating taurine levels due to reduced transporter expression. Some have reported that dietary availability thus has relatively little impact on circulating taurine. Combined, these observations suggest that supplementation would be useless in increasing circulating taurine levels in those already within typical physiological ranges. (Data in humans with unusually low taurine levels, as is often seen with obesity, kidney disease, or strict vegan diets, suggest that supplementation does indeed raise serum levels in these individuals.) Any excess either wouldn’t be absorbed or would be excreted. And if taurine levels decline with age due to an increase in excretion, the threshold that defines “excess” taurine is effectively reduced. For instance, a taurine concentration of 50 µmol/L in a 20-year-old could be raised with supplements, but the same level in a 60-year-old might represent an upper limit. In this way, we can liken the body’s taurine levels to water collecting in a bucket. As long as the bucket isn’t full, the water level will continue to rise as more is added. But once it reaches the top, any additional water will simply spill over the edge and the amount of water in the bucket can increase no further. Now imagine that over time, the bucket rim slowly erodes, resulting in a shorter and shorter bucket that can hold less and less water. No matter how much water you add, the bucket will never contain as much as it did before. So why did supplementation “work” in mice? Again, it may relate to a difference in their taurine biology relative to humans. In addition to the three possible explanations described above for the decrease in taurine with age, mice may have another contributing factor that would be largely irrelevant in humans: a decline in endogenous synthesis. Like reduced absorption, this explanation would also suggest that supplementation could have a meaningful impact in elevating circulating levels. To use the bucket analogy again, a loss of taurine due to reduced absorption or synthesis would be comparable to slowing the rate of water flow into the bucket to a point at which the rate of evaporation outpaces the rate of water collection, and the water level gradually drops despite the fact that the bucket remains the same size. In this case, supplementation with another water source would be helpful in refilling the bucket."

@larsnystrom6698

Жыл бұрын

@kurtniznik8116 I think we need to know more about this. But my guess is that we get most taurine from the bodys own production of it. And much less, perhaps half, from animal food. Taurine is produced from cysteine, which we don't get enough of, and needed for many other things. (Glutathion, Creatine) It's my guess that absorbtion isn't a problem. It's likely the bodys production which is reduced with age.

@nomandad2000

Ай бұрын

Interesting. I’d like to see a retort to this. But so far, silence.

Thanks for another great video! Note that despite all the positives for hypotaurine the study doesn't discuss hypotaurine induced colorectal cancer which is well researched elsewhere.

Excellent video.

I don't currently supplement with taurine, although I am considering it. I found the section on WBC quite interesting because my recent lab results showed a low WBC which was initially concerning to me. However, I did some research and discovered that a slightly reduced WBC count is an indication that your immune system is likely optimized, i.e. your white blood cells aren't being called upon as much to fight infection and therefore are naturally lower. Lower WBC is indeed an indication of reduced inflammation. I should mention that I am very healthy... I do IF, exercise daily and take high quality immune boosting supplements, so a low WBC makes sense for me.

I haven't watched the video yet, just read the title, but what I can tell you is, that I used to drink a lot of red bull (which contains Taurine) for most of my teens and 20s... im 27 now, and not drinking it as much anymore.. but as a 27 year old, I still get mistaken for a 16 year old sometimes, literally the other day I couldn't buy cigarettes for my mother because they were not sure if I was 18 or not. Maybe I should add that I'm vegan and also very careful about being in the sun and using spf.. so that probably adds to it too

@CampingforCool41

11 ай бұрын

Yeahhhh I’m pretty sure it wasn’t the Red Bull that kept you looking young lol. A combination of good genetics and good skin care/sun protection will do the job.

@chuckleezodiac24

10 ай бұрын

if you avoid the sun and eating animals, make sure you're getting enough Vitamin D.

Another video speculating on the optimum human dose would be great!

Excellent analysis 👍