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Walnuts + creatine = super brain. Seriously, try it. Mediterranean diet helps too.

Am i the only one who likes even before the video starts? 🤣

@Physionic

2 жыл бұрын

I do it, too. 😉 Thanks, Richard.

Great Info and analysis.

Really interesting video!! More brain videos please, go off on that tangent about astrocytes, neurones and all those other brain cells.

@Physionic

2 жыл бұрын

Haha, I feel a minority of people might like that, but thank you for granting me the nerdity.

Thank you for the video. Your graphics are helpful and to the point, not too much not too little. Astrocytes are my favourite glia, they deserve to be a topic of one of your videos. Started supplementing with creatine today 💪🏻🧠

Another fantastic review of the literature, thanks very much

A video about your workout routine and best practices to optimize longevity, muscle growth-maintenance and health in general would be awesome.

@Physionic

2 жыл бұрын

Great, thanks for the feedback, will do.

@MarcColbeckCCP

2 жыл бұрын

I'll second that! :-)

@harku123

2 жыл бұрын

He did make a podcast once where he went into his workout program. I don't remember how detailed it was but it's a few months ago now, maybe it has changed since

@1122redbird

Жыл бұрын

@@MarcColbeckCCP Me too. Would like to see that one.

@nl3712

Жыл бұрын

Second that request

you provide the best content out of everyone, keep doing what you do

@Physionic

11 ай бұрын

Thanks, Tony - really kind of you. I have much to improve.

Great video.

"I don't want to get into the weeds with this" Hey! That's where we all are. We live and thrive "in the weeds".

I think there's one more interesting thing about Creatine. ATP, or rather ADP is such a large molecule that it isn't so mobile. While Creatine is much more mobile. So, Creatine can much more easily move to the Mitocondria, to be reloaded with energy, i.e., a phosphate group. This system is therefore more effective than just having more ATP would be. Is this too much detail? I think it's very illuminating!

Good content, deserves more subs

@Physionic

2 жыл бұрын

Thanks, MJagad P - kind of you.

Fascinating.

Dziękujemy.

@DILFDylF

Жыл бұрын

You can't say that.

Curious if anyone has tried GAA Guanidinoacetate Acid. I saw someone on read it say that it had some potential for neurotoxicity. Anyway, I'm very thankful for this video because I'm only taking three grams of creatine and I realized that just won't cut it for brain benefits.

Thank you for this and your wisdom! Hey I tried to look for the supplement but was unable to find anything. Any recommendations?

Creatine is also useful for people who suffer from muscuar and/or tendon pain/injury as a result of using statins. Not much research on the topic in the U.S but some in Europe. I can personally attest it's worked for me.

@LTPottenger

2 жыл бұрын

do some fasting and eat lots of protein and collagen

@larsnystrom6698

Жыл бұрын

@ohplezz One reason statins are bad for muscles and other things, is that it reduces CoQ10. That hits the energy system! So, if I were to use statins, I would supplement with Ubiquinol, which is said to be the best form of it. There might be other things too, but I will never use statins, so I haven't really looked into it.

@larsnystrom6698

Жыл бұрын

@ohplezz By the way, I got tendinitis in the tendon of biceps longum. At the time, I didn't realize that I needed Collagen! I started using Collagen because the skin on my lower legs got thin and sensitive. That's now gone. It might be enough with just protein when younger. But when older we need both protein and collagen, or at least more glycine.

Id like to know what helped you write a book. Who did you emulate? Where did you get your ability to put it together.

Are there any guanidinoacetate supplements out there? Or would one simply take precursor aminos?

Thanks for sharing, Nic. I've ordered a 300gr box of creatine for my wife and I. Would you say it's also safe to supplement creatine for 8-year old boys? The school system here is absurdly demanding and my kids regularly don't get enough sleep. Can creatine support their brain health?

27:58 Glycine & arginine react to produce GAA. Is this the same glycine as in GlyNAC? Would it be posible for GlyNAC to increase GAA? Do we need to take arginine as well? So many questions :)

Interestingly a few years back I misread and started taking 5gms creatine 3 times a day instead of 1 time a day, and I did that for probably more than an year or so and I remember that during that period I used to feel twice more pumped up in the Gym, was able to perform much better in the Gym without much exhaustion, recover faster and was mentally more active! and I don't remember feeling any side effects. But then I corrected myself as per the recommended dosage (5gms once a day) realising that I was taking way too much compared to recommendation and now I saw this video! 😊 Now I am honestly confused what's the right course for me.

@gabrielbernard5440

Жыл бұрын

If you felt better with the dosage three times a day, why not keep doing it? It seems your body did like it. Like with everything, check if there could be any side effects, and if not, what should stop you from experimenting with it?

@memeticist

Жыл бұрын

The bodybuilding community has always used a one week loading phase of 25 gms per day and a maintenance of 5 gms. That loading phase is repeated every few months or so.

@vipulgupta

Жыл бұрын

@@gabrielbernard5440 Yes I agree. I plan to do it again. But after trying with the increased dosage I would get my serum creatinine levels checked in a week, then after 1, 2 & 3 months. If the serum creatinine levels are normal even after 3 months, then that would mean my body is accepting it.

Does insuline pump play a role? It does musculo-centric-wise 🙂 *Actually it could be counterproductive when the muscles suck it all in

"A new molecule......!" 😂

Try green tea matcha blackberry carnosin d3 and k and a

My serum creatinin level is 1,31 mg/dl which is relatively high and I am not sure if I maybe should stop supplementing. Also, I have a low GFR and my friend (medical student) is concerned about my kidney function but I believe it comes from the supplementation because the GFR is calculated from the creatinin level.

@Physionic

2 жыл бұрын

I'm sure the creatine is contributing. I don't know if you've seen my creatinine video on "if you should be worried", but there are other renal tests you can conduct, as well. If you're worried, as I'm sure you know considering your education, you could just stop for 2 weeks, check your kidney function, and assess. Or, simply try a non-creatinine related kidney function test instead of looking at creatinine.

Quick question on your comment that the body's own creatine production stops while supplementing. Can you see a slight energy profit here as the cost or creating required levels of creatine is removed while it is supplied exogenously?

@Physionic

Жыл бұрын

That's a good question - I'd guess the effect is negligible when considering whole body metabolism.

A hypothesis: supplementing creatine reduces the level in the brain! It would/could happen because the bodys production of guanidinoacetate in the kidneys is reduced because of supplementation, so the brains uptake of this molecule is reduced. The brain therefore produces less creatine. This is just my spekulation and may be wrong. One way of that would be: If the brain produces it's own guanidinoacetate from glycine and arginine, my hypothesis would fall because these two would be more available to the brain if the body didn't have to produce creatin. So, then suplementation would increase the level in the brain. Which is it?

@Protolamna

6 ай бұрын

Brain produces its own Guanidinoacetate

Hi physionic do you know if I can still get a great physique if I start at age 30? I heard that we lose muscle past 30 and I am worried, or is it a very gradual decline?

@Physionic

2 жыл бұрын

Absolutely. You do not lose muscle at 30. Decrements in muscle begin in your 50s and is gradual (this data is also in individuals who do not lift).

@bennybenny7382

2 жыл бұрын

@@Physionic Thank you

Is there any reason why creatine would or could cause pain in the testes? I stop taking it several decades ago because of that. Now that I'm much older, I am wondering if there might be any benefit now with that side-effect?

@limitisillusion7

Жыл бұрын

I don't know about that, but I do know that you have to increase water intake with creatine. It's possible you weren't drinking enough water.

I've used creatine, and it works very well for me: my belly disapeares under my ribcage, my shoulders go to the sides and I'm ready every moment to make a sprint. But.. it gives me muscle cramps. Very painful at the moment, and to a lesser degree when using that muscle over the periode of a week. I'm sure the dosage I used is far less than the 4 times 5 gram per day. I read all the comments to see, but nobody mentions muscle cramps. Am I the only one who has that? Is it because I've put the creatine in my coffee?

@spammers8646

Жыл бұрын

I read somewhere that you need to drink more water when you are taking creatine. So your muscle cramp might be due to dehydration

@grainiac7824

7 ай бұрын

I was advised to take it to RELIEVE muscle cramps in addition to brain health

@Tate525

7 ай бұрын

Take it with salt and have adequate water. Along keep potassium and magnesium intake in check.

Any thoughts on the quality of the creatine? The market is flooded with Chinese made creatine and I'm nervous about its quality....

Any tips for Findling GAA? All i find is shady fitness stuffs that i do not trust. Take care.

Don't forget to add that it's not good to combine with a high carb diet. It only works well with a low very pow carb diet.

Creatine vs TMG (Betaine) Supplementation ?

Interesting study but 20g/d is too much creatine. I've been taking creatine on and off over the past several decades as a weight training supplement. It's no doubt very effective thereto, as it _significantly_ increases strength permitting heavier weights to be lifted. Problem is that for me after prolonged usage it causes noticeable bloating. I never experienced any mental benefits probably because the dosage was too low. I don't see creatine as a good nootropic supplement for these reasons. Better options out there. Will do research regarding GAMT as a viable more effective alternative.

Can you talk about alcar ? Dosing , some people take 5g , safety ? some recommend 500mg ? Taken everyday?

How do they check the creatine levels in the brain vs the body?

@Physionic

2 жыл бұрын

Animal studies. Biopsies of brain matter.

Do you think if you supplement creatine for long periods of time, that your body would slow it’s production after you stop?

@Physionic

2 жыл бұрын

After you stop? No.

@topherstudios5297

2 жыл бұрын

@@Physionic thank you, if I would have waited a few more minutes I would have seen you addressed it lol. My bad, thank you.

@Physionic

2 жыл бұрын

No worries, happy to help.

Brain power like listening and comprehending your programs? 🤔

To conclude.... high dose creatinine before watching your channel!

@Physionic

2 жыл бұрын

Well, maybe not creatinine, but creatine, haha.

@littlevoice_11

2 жыл бұрын

@@Physionic clearly I hadn't supplemented before commenting

@Physionic

2 жыл бұрын

@@littlevoice_11 haha!

Can you smoke weed while taking creatine.

@Maxumized

8 ай бұрын

I guess you’re high…too late

@romerome6968

8 ай бұрын

@Maxumized I guess il just smoke more

This is really helping me however I'm starting to suffer from diarrhea. Any suggestions?

@Physionic

2 жыл бұрын

Try a different formulation of Creatine. I’m assuming you’re using monohydrate.

@tombrougham6415

2 жыл бұрын

@@Physionic I have and it seems to have worked. Yes it is monohydrate. Would you recommend a different type? Your work is brilliant by the way.

I read somewhere that a high dose of creatine is tough on the kidneys. Is there any truth to that?

@Physionic

16 күн бұрын

Have video

Hey this was a very interesting Video. I am gonna give it a try with about 11 g Creatine for braun effects . I did Not find sources for GAA in Germany so i will try It It with Creatine. I am suffering in a brain damage due to a lack of O2 i Want to see If it has some positive effects on my mind/brain and please do Not worry . This Video is not my only source for this decision . If you are interested i can Tell you about the results after 2 months p.e greetings

@kyler565

Жыл бұрын

How did it go? Did creatine help?

@vairotsana108

Жыл бұрын

@@kyler565 hi i could not Finish it for two reasons. First i received a therapy to improve brain fuctions espcally memorizing Things . The reason for that Is that my brain is Generally damaged because of a lack of oxygyne since my birth. So the therapy effect would be a massiv bias to the Creatine effect. Second reason I live in Germany . I could not find a company that would supply the supplyment here. For that reason i try to consume very high Dosis of creatine to aim the transport mechanism to the brain as it was explain in the Video. This Method was impractical. I needed to swallow a Lot of capsules and of cause I had to Drink a very high amount of water in a Short time . And still i Had slightly Problems to digest These amount of capsules Greetings from Leipzig Germany Tobias

@rogerbritus9378

Жыл бұрын

@@vairotsana108 Good luck, Tobias! Rooting for you here.

nice video, but to say that creatine protects your brain from trauma is kind of a lip/extrapolation, the fact that the brain have less creatine in cases of constant head trauma, does not mean that suplementing it. will fix things...more research in humans is needed for this assumption. right?

Please dont do sound effects, the content of what you say is what I want to hear, not quirky sounds or visuals

This video could have value if it was 3 minute long. There is like 1 min of content but 2 extra minutes of fluff would be ok.