Brilliant!!! What ive been looking for. Your guest is a gem❤❤
@MissionCure5 күн бұрын
We're so glad it was helpful!
@1teritucker17 күн бұрын
Can taking too many enzyme capsules cause constipation
@johnapple78418 күн бұрын
Thank you for highlighting this area! There are few doctors that really understand the impact of EPI. Dr. Freedman also has an in depth article on Exocrine Pancreatic Insufficiency written with Dr. Struyvenberg that anyone with EPI should read. Another really helpful resource was the book Primal Pancreas.
@andrewsharongolding813920 күн бұрын
I was diagnosed with EPI after a low fecal elastase test (72) last year, and I have been on PERT since then. I had been suffering from chronic IBS, diarrhea, weight loss, bloating, abdominal pain, and the PERT (Zenpep) seems to be helping with these symptoms, although I still have trouble maintaining weight and have occasional abdominal pain in the right side of my abdomen, below the rib cage and above the navel. I recently had my elastase retested, and my numbers are now above 400. My question is: was I misdiagnosed due to the poor stool quality of the first test, or can I still have EPI even with elastase numbers in the normal range? I've had multiple CTs, an abdominal ultrasound, PET scans and an MRI. No abnormalities were found. I plan to stay on PERT, but I'd sure like to know the hows and whys of my condition. My PHP was unaware of EPI until my case.
@AbdAlgani199923 күн бұрын
thank you man
@user-ix8is2sx2b26 күн бұрын
Well Explained Mam, I am suffering from CCP along with Type 3c Diabeteis for 20 years. Excellent Presentation about Pancreatitis
@MissionCure26 күн бұрын
We're glad you found this webinar informative!
@taimoorjutt5738Ай бұрын
Salam! I am from Lahore, Pakistan. I have been a patient of chronic pancreatitis for the past 16 years due to pancreatic divisum. Multiple endoscopic procedures like EUS, Gastroscopy, ERCP with sphincterotomy and stenting has been done. My gallbladder is surgically removed through laproscopy in 2017 but still there is no pain relief. Now almost 5 months ago the celiac block was done in PKLI hospital, Lahore. In this duration of 5 months i am feeling better because of pain relief but now my pain started again from last 10 days. I am totally exhausted and frustrated from life due to the constant severe abdominal pain. I am using strong opioids painkillers such as toradol, tramadol, nelbuphine and even morphine but there is no pain relief even for a micro second. I am always screaming and crying due to the pain severity. Sometimes, i thought about suicide because i have no more potential to bear this severe abdominal pain of chronic pancreatitis. Doctors advised me to go for a Whipple Surgery with Total Pancreatectomy but they said there is a lot of death risk and we cannot guarantee you the pain relief even after Whipple Surgery with Total Pancreatectomy due to this i am confused about the Whipple Surgery with Total Pancreatectomy. If you have a complete cure and better/definite treatment for this dreadful disease then please help me. My WhatsApp Num +92332-4779047 Email address : [email protected]
@marionmeister4268Ай бұрын
I have a 5y old son with severe EPI. He weighs 13kgs and is sevely disabled. What dosage applies in his case? Or does weight not matter?
@MissionCure22 күн бұрын
We're sorry to hear about your son's severe EPI. The appropriate dosage of pancreatic enzymes often depends on both age and weight. It’s crucial to work with a pancreatic specialist who can tailor the treatment to your son's specific needs. Here are some resources that might help: PERT Dosing Guidelines: For detailed information on dosing guidelines based on age and weight, please visit our webpage: mission-cure.org/pancreatic-enzyme-replacement-therapy/ Managing EPI: Learn more about managing Exocrine Pancreatic Insufficiency (EPI) here: mission-cure.org/complications-of-chronic-pancreatitis/exocrine-pancreatic-insufficiency/ We highly recommend working closely with a pancreatic specialist to ensure your son gets the right dosage and to monitor his progress. They can provide the best advice and adjustments needed for his condition.
@fransgolden1068Ай бұрын
Wish my specialist was so informative
@MissionCure22 күн бұрын
We are glad you found our resource informative!
@dollyrocker40Ай бұрын
Im type 3c lost most of my pancreas to goldstones for the pancreas tissue left 17 years ago now
@oscardelrio637Ай бұрын
What about the cholesterol medicine cousin pancreas!! Now what
@darrellborder8555Ай бұрын
Thanks for your lecture. I’m amazed how few doctors understand this disease, but most are happy to push drugs that they have limited experience with and not sure of the efficacy. Seems like the cure is available, but there’s no money to be made from it. You have low views so you’re on to something!
@christinemartin4316Ай бұрын
I would suggest getting arms xrayed. That is how I found out and it’s an early sign.
@MissionCure22 күн бұрын
We're glad to hear that it was caught early!
@justcharlie6164Ай бұрын
Thanks so much for uploading/making this! I got out of hospital today, diagnosed with acute pancreatitis a couple months back and now its chronic with some necrosis. This has helped me feel reassured and your website is amazing, so much great information! I learned way more in this video than over 2 weeks in hospital, really appreciate it. I'm going to try to come back to this video once a year to comment :)
@MissionCureАй бұрын
We're so glad the video and our website have been helpful and reassuring!
@lanahabash3627Ай бұрын
Hello there,I’m diagnosed with severe EPI , gastronologist never looked in to the cause I have pain on my left med back, and abdominal pain and gastrointestinal issues,would I qualify for clinical trials
@MissionCureАй бұрын
For a thorough evaluation of your severe EPI and related symptoms, we recommend consulting with a pancreas specialist or a gastroenterologist who specializes in pancreatic conditions. They can help determine the underlying cause of your pain and gastrointestinal issues. To participate in clinical trials, a detailed diagnosis is typically necessary to assess whether you meet the eligibility criteria. You might find our diagnosis toolkit(mission-cure.org/pancreatitis-diagnosis-toolkit/) and diagnosis webinar (kzread.info/dash/bejne/Y6dk2q2PdLueobw.html) helpful as you seek further evaluation.
@chetnajaiswal75Ай бұрын
@@MissionCure i have chronic pancreatitis and epi and my weight is constantly decreasing.in april 2024 iwas 39 kg..in 2022 i was 53. my doctor gave ct scan and bllod test that appears normal but have stone and mpd in head. He said i will not intervene it right now.. he said i think u have bacterial overgrowth which is quite common in chronic pancreatitis patients. So he gave me antibiotic (rifagut) and normaxin..and creon 25k three times a day..my epi level is 4..i gained weight in this two month but only 1 kg..can you please help me how can i gain weight and is this a severe problem?
@imtryinghere1Ай бұрын
Best video on epi on KZread. Concise and detailed
@MissionCureАй бұрын
Thank you! We're glad you found this EPI video helpful.💙
@omraz78642 ай бұрын
Can e.p.i cause dry skin like eczema i have floating oily stools and do local gp test for epi pluss ive realised enzymes over the counter are not strong enough which ones would u recommend?
@MissionCureАй бұрын
Hi there! Exocrine Pancreatic Insufficiency (EPI) can cause vitamin and mineral deficiencies, which may affect your skin and hair, sometimes resulting in conditions like dry skin or eczema. Floating, oily stools are a common symptom of EPI. For testing, it’s best to consult with a specialist rather than relying solely on a general practitioner (GP). They can perform specific tests for EPI, such as a fecal elastase test. Over-the-counter enzymes are often not strong enough. We recommend looking into FDA-approved PERT brands, which you can find on our website: EPI Webpage: mission-cure.org/complications-of-chronic-pancreatitis/exocrine-pancreatic-insufficiency/ PERT Webpage: mission-cure.org/managing-pancreatitis/pancreatic-enzyme-replacement-therapy/ For more detailed information, check out our EPI playlist and our vitamin and mineral deficiency videos: EPI Playlist: kzread.info/head/PLJXha4Nvx8NJRu03C4kOj3CyoqjvB_Q6u&feature=shared Nutrition & Vitamin and Mineral Deficiency Videos: kzread.info/head/PLJXha4Nvx8NIxUzyrWc8ec0plt44vpMo4&feature=shared
@46doony2 ай бұрын
The prescribed pancreas enzymes im taking are creating pancreatitis.
@MissionCure22 күн бұрын
We're sorry to hear that the prescribed pancreatic enzymes are causing you discomfort. It's important to address this with your healthcare provider to ensure you get the right treatment without adverse effects. Here are some points to consider: FDA-Approved PERT: Pancreatic Enzyme Replacement Therapy (PERT) is FDA-approved and should be prescribed by a healthcare provider, rather than over-the-counter supplements, to ensure proper dosage and effectiveness. Side Effects: PERT can have side effects, and it’s essential to monitor how your body reacts. Discuss any adverse reactions with your doctor to adjust the treatment as needed. EPI Playlist: We have a playlist with videos that provide insights into managing Exocrine Pancreatic Insufficiency (EPI) and using PERT effectively. You can find it here: kzread.info/head/PLJXha4Nvx8NJRu03C4kOj3CyoqjvB_Q6u&feature=shared Consult a Specialist: Working with a pancreatic specialist can help you find the right fit for your condition and manage any complications. They can provide personalized advice and adjustments to your treatment plan.
@user-we5tp8jd2p2 ай бұрын
I never have a formed stool. How to test?
@dancethenightaway70Ай бұрын
Stool test must be a formed stool or it will always come back low.
@MissionCureАй бұрын
To test for Exocrine Pancreatic Insufficiency (EPI), it’s best to consult with a doctor. They might recommend a fecal elastase test and possibly a 72-hour fecal fat test. Additionally, blood tests for vitamin deficiencies and imaging studies like CT or MRI scans of the pancreas might be needed. A specialist can help determine if your loose stools are due to EPI or another underlying cause. Sometimes, they may treat it with Pancreatic Enzyme Replacement Therapy (PERT) to observe the response and then order a test on a formed stool. Hope this helps!
@HarpreetKaur-ti2xp2 ай бұрын
Hi doctor do loss of. Normal pancreatic lobulations means auto immune pancreatitis??
@MissionCureАй бұрын
Loss of normal pancreatic lobulations isn't specific to autoimmune pancreatitis (AIP). This change can also be seen in other conditions affecting the pancreas, including various types of pancreatitis. A definitive diagnosis should be made by your healthcare provider and a pancreas specialist, who will consider your clinical symptoms, lab results, and imaging studies. If you're in the US, we recommend consulting with one of the experts listed in our autoimmune pancreatitis blog. They can provide more personalized advice and help address your health needs and queries. AIP Blog: mission-cure.org/autoimmune-pancreatitis-symptoms-diagnosis-and-treatment/
@gerryrichardson92523 ай бұрын
Is there any help for EPI in the pipeline?
@MissionCureАй бұрын
There are ongoing developments in the Pancreatic Enzyme Replacement Therapy (PERT) space, with several companies working on creating more efficient and effective products to help manage EPI better.
@NaveendvGUEE3 ай бұрын
Very informative doctor. I am diagnosed with chronic pancreatitis since when I was 13 and now I am 26 and from last few month I am recovered from stetorreah but my farts are so smelly and this exists even I don’t take a meal…. Can you help me here please?
@MissionCureАй бұрын
Hi there! We're sorry to hear about the difficulties you're experiencing. Many patients with chronic pancreatitis face similar challenges. Our holiday tips video provides advice on managing such conditions when you're out in public, which you might find helpful. Additionally, we recommend working with a gastroenterologist to rule out any digestion-related conditions that could be causing the issue. Maintaining a well-balanced diet with a good amount of fiber can also be beneficial. For more detailed tips, please check out our nutrition webinar. Wishing you the best! Holiday Tips Video: instagram.com/reel/C1Hh4iqNaR7/?igsh=MzRlODBiNWFlZA== Nutrition Webinar: kzread.info/dash/bejne/m4tnsc6MYbS2l5M.html
@Healthy-Golden-Oldie3 ай бұрын
Pancreatitis and Covid... there may be indications that the spike protein can cause IGG4 which in turn might have a relation with AIP. Is this true and being researched?
@MissionCure3 ай бұрын
There is some research exploring the impact of COVID-19 on various bodily functions, including the pancreas. While there are indications that the virus could affect pancreatic functions, conclusive evidence linking the spike protein specifically to IgG4 production, which is associated with AIP, is still being researched. For a deeper understanding of AIP and its association with IgG4, you may find our video on AIP symptoms, diagnosis, and treatment helpful: mission-cure.org/autoimmune-pancreatitis-symptoms-diagnosis-and-treatment/ Additionally, here are a couple of studies that discuss pancreatic injuries related to COVID-19: www.ncbi.nlm.nih.gov/pmc/articles/PMC9021704/ www.ncbi.nlm.nih.gov/pmc/articles/PMC7118654/ www.mdpi.com/1422-0067/23/2/864 These resources might provide further information that you can discuss with your healthcare provider.
@chetnajaiswal75Ай бұрын
@@MissionCure is it common to have bacterial overgrowth as a chronic pancreatitis patient.. my epi is 4 and recently i lost 10kg after ct scan of pancreas it seems normal but according to my loosing fat and body mass doctor said may be you have bacterial overgrowth qs symptoms indicate towards it..i am not diabetic..i am taking rifagut400..can it will be difficult to gain weight agai ? Plz explain
@chetnajaiswal75Ай бұрын
And yes i am taking creon 25k 3 times a day only. Pls make a video on it
@Healthy-Golden-OldieАй бұрын
@@chetnajaiswal75 I benefitted a lot from fasting. It seems counterintuitive when you are losing weight, but it really helped to restore my gut microbiome. After that I started to gain weight and symptoms like bloating disappeared. Now I fast every time I feel it is necessary. I guess that, because of malfunctioning pancreas, bad bacteria (and bacteria in the wrong place in your gut) get a chance to develop. Despite supplementing pancreatic enzymes. Fasting may restore balance. Consult your doctor to see if this might be an option for you.
@kimielambert96133 ай бұрын
I suffered for 22 years. So grateful for enzymes❤ This video sheds a lot of light on how this happened.
@starrleo123 ай бұрын
He just gave me my diagnosis within the first minute of the video!
@sheilamulcahy27813 ай бұрын
Is osteoporotic bone loss compounded when chronic pancreatitis (EPI), primary hyperparathyroidism, renal insufficiency, and total gastrectomy (secondary to NET) are experienced simultaneously? Do you think these comorbidities are connected despite a healthy lifestyle with good nutrition?
@MissionCure3 ай бұрын
A healthy lifestyle and good nutrition are definitely factors that will positively influence overall health and well-being, but diseases, including Chronic Pancreatitis, have multiple causes. A progressive disease like CP represents an increased risk of EPI, bone disease, and other possible co-morbidities. For more detailed information about the complications associated with chronic pancreatitis, please visit our resource page: mission-cure.org/complications-of-chronic-pancreatitis/ We highly recommend consulting with a pancreas specialist and assembling a multidisciplinary care team to tailor the treatment to your specific needs.
@chetnajaiswal753 ай бұрын
I have chronic pancreatitis and epi and i was 50 kg in 2022 but since 2023 i lost 10kg weight now i am 40kg.. my epi is 3.5( fecal elastase done on sep 2023)..i am currently on creon 40k three times a day..please help me..why it is happening what should i do.? How i can gain weight? My doctor is not taking my health issues seriously
@MissionCure3 ай бұрын
We're sorry to hear about your struggles with chronic pancreatitis and EPI. For more information, please visit our pages on Exocrine Pancreatic Insufficiency (EPI) [mission-cure.org/complications-of-chronic-pancreatitis/exocrine-pancreatic-insufficiency/ ] and Pancreatic Enzyme Replacement Therapy (PERT) [mission-cure.org/managing-pancreatitis/pancreatic-enzyme-replacement-therapy/ ]. These resources can help you discuss your care more effectively with your doctor. We also recommend exploring the FDA dosage guidelines on the PERT page and watching our videos on EPI management [kzread.info/dash/bejne/a3el0JWug9upgtY.htmlfeature=shared ] to see if your current treatment protocol aligns with recommended practices.
@ninadperiodon3 ай бұрын
does bicarbonate tablet taken with enzymes will help?
@MissionCure3 ай бұрын
It's important to consult with your healthcare provider or gastroenterologist to find the option that works best for you.
@ayeshaogloblina21274 ай бұрын
What if I have tried so many pancreatic porcine enzymes and I have side effects from them and the only options are now OTC pancreatic vegan enzymes ? Also is this normal ( I have severe EPI lab 86 and chronic pancreatitis ) that before diagnosis I did not have runny stools but just constipation won’t enzymes constipate me even more ?
@MissionCure3 ай бұрын
We encourage you to visit our PERT webpage (mission-cure.org/managing-pancreatitis/pancreatic-enzyme-replacement-therapy/ ) to learn more about enzyme therapy options. Currently, there are no FDA-approved vegan enzymes available for treating EPI. It's important to always consult with your healthcare provider or gastroenterologist to explore the most suitable and effective treatment options for your specific condition.
@johnsims56114 ай бұрын
Thank you God bless
@KM-vc7iy4 ай бұрын
So no clinical trials 2 years on?
@MissionCure4 ай бұрын
Neither of these projects is in clinical trials, unfortunately, but there is the trial of paricalcitol for chronic pancreatitis, a few other studies, and 2 more recurrent acute and chronic pancreatitis therapy trials starting soon. Check our website, mission-cure.org/clinical-trials-and-strategy/our-cure-strategy/pancreatitis-clinical-trials/.
@babygonda12264 ай бұрын
My stomach is in pain after takingEmzymes
@MissionCureАй бұрын
We're sorry to hear that you’re experiencing stomach pain after taking enzymes. Some patients do report side effects with PERT (Pancreatic Enzyme Replacement Therapy). It’s important to work with your doctor to pinpoint the cause of the pain and see if it's related to your PERT therapy. They might suggest trying different digestive enzymes. You can also find more information on PERT dosage and possible side effects on our PERT webpage: mission-cure.org/managing-pancreatitis/pancreatic-enzyme-replacement-therapy/ Hope you feel better soon!
@ShahiD-tb3ni4 ай бұрын
i'm 28 nd taking Kreon 10000 2 capsules per meal
@dcole63284 ай бұрын
why has this become so common recently? could this be related to Covid or to Covid vaccines?
@MissionCure3 ай бұрын
There is some research exploring the impact of COVID-19 on various bodily functions, including the pancreas. While there are indications that the virus could affect pancreatic functions, conclusive evidence is still being researched.
@ThanhTran-333334 ай бұрын
I had developed severe Exocrine Pancreatic Insufficiency post Covid. I have pain in the L and R upper quadrant. Pls advise which tests I need to diagnose chronic pancreatitis? Thanks 🙏
@MissionCure4 ай бұрын
We are sorry to hear of your symptoms and the diagnosis of EPI. Please visit our webpage where causes and symptoms of CP have been detailed, linked here: mission-cure.org/chronic-pancreatitis/ You can also have a look at our diagnosis webinar and toolkit to help you navigate your conversation with your doctor linked below: Toolkit: mission-cure.org/pancreatitis-diagnosis-toolkit/ Diagnosis webinar: mission-cure.org/pancreatitis-diagnosis/
@SuperMjennings4 ай бұрын
I’ve been STARVING for this information ever since diagnosis (while hospitalized for malnutrition 😬)!
@CandycaneBeyond4 ай бұрын
22:32 has it occured to anyone that possibly because people are following low fat diets that its creating this problem? I thought we were supposed to eat fatty fish and butter on a regular basis? Olive oil and lamb? Isn't that what the Mediterranean diet is? If our gallbladder isn't being used often enough, it seems like it gets clogged, lazy and malfunctions.
@MissionCure4 ай бұрын
Thanks for your input. Pancreatitis has various causes, including gallstones. As our expert highlights, there's no one-size-fits-all diet recommendation for all pancreatitis patients. Clinical research evidence suggests a positive relationship between fat content and exacerbation of symptoms in some patients. We always recommend patients work with their doctors and dietitians to find protocols that suit their specific needs, which are multifactorial. You can explore our nutrition webpage for more information on the topic:mission-cure.org/managing-pancreatitis/nutrition-for-chronic-pancreatitis/
@user-we1te4sd2o5 ай бұрын
I just started Creon Dr 2400 units
@jmtrs795 ай бұрын
My daughter was inpatient and they determined acute pancreatitis. My prideful MIL kept from us the fact that her mother died from pancreatic cancer. It’s truly sad when family cares more about pride than their own grandchild.
@SuperMjennings5 ай бұрын
I learned more in this one video than I learned during a recent admission in hospital x 1 week.
@MissionCure4 ай бұрын
Thank you. I'm glad you found it useful. I hope you've subscribed to our channel. Megan
@mpoharper5 ай бұрын
I got it from immunotherapy! I don’t see much on this topic. The pain was awful. It involves pancreas only and comes back when I wean off prednisone. No elevated igg4.
@MissionCure4 ай бұрын
Hello @mpoharper, we are sorry to hear this. We raised your query with our expert and have some feedback and additional info. Could you write to us at [email protected] and mention your comment so we can respond with more details? Thank you!
@mpoharper4 ай бұрын
@@MissionCuresure
@HarpreetKaur-ti2xp2 ай бұрын
Hi. , can the loss of normal pancreatic lobulations indicates auto immune pancreatitis?
@mpoharper2 ай бұрын
@@HarpreetKaur-ti2xp I don’t know. My gastrointestinal doctor was useless in this regard.
@HarpreetKaur-ti2xp2 ай бұрын
That’s unfortunate, they let people suffer like this
@mpoharper5 ай бұрын
I developed pancreatitis from checkpoint inhibitors. Adding digestive enzymes really has helped reduce prednisone. I will hopefully get off prednisone all together!
@mpoharper3 ай бұрын
I have been off prednisone for a month and pancreas appears to be doing well! Enzymes made a big difference!
@robertb20595 ай бұрын
Was your daughter a carrier of CFTR or did she have CFTR? I am a carrier of CFTR, but don't have CFTR. I have Pancreatitis and am on creon. Within the last two years I lost two brothers to pancreatic cancer! Brothers age were 55 and 57. Way too young to die! Doctors never did figure out the cause of the disease!
@MissionCure22 күн бұрын
We are so sorry to hear about the loss of your brothers. Here are some resources that might be helpful: Learn more about the role genetics play in pancreatitis: mission-cure.org/genetics-and-pancreatitis/ Our Genetics in Pancreatitis Toolkit provides valuable information: mission-cure.org/pancreatitis-genetic-testing/ Seeking support from a pancreatitis specialist can also be crucial in managing your disease effectively.
@billstreat82355 ай бұрын
I am in unbearable pain. Been in 4x. They put me on oxys 10 instead of 7.5 I would just love my pain to let up. It's horrible
@MissionCure3 ай бұрын
We're really sorry to hear this. Take care 💙
@alexmartinuzzi67552 күн бұрын
Hey I hear you, here in Michigan I've been to hospital a few times now been back and forth to the doctor for years. Not once given pain killers. 😢 yet I've also never been a opioid or even a drug user! I have no history of drug abuse yet my doctor never talks about using even a low dose painkiller like a hydro or something. I'm just surprised it depends where you go in the country for sure! Good luck with your struggle keep going don't give up
@dawn69545 ай бұрын
Recently diagnosed with this but omg the medicine is $900/month with insurance! I cant afford it! :(
@dancethenightaway705 ай бұрын
Creon has a assistance program which include vitamin and mineral supplements.
@dawn69545 ай бұрын
@@dancethenightaway70 omg THANK YOU!!!
@MissionCure3 ай бұрын
You can find information on PERT savings programs here: mission-cure.org/pancreatitis-resources-and-support/ Hope this helps!
@ashleye12145 ай бұрын
Do you think there is a correlation between CF carriers and acute to chronic pancreatitis?
@MissionCure5 ай бұрын
Hi Ashley! Yes, the CF (CFTR) gene can play a role in causing chronic pancreatitis. For more information on CFTR and genetics and pancreatitis, visit: mission-cure.org/chronic-pancreatitis/genetics-and-pancreatitis/
@silentgirltears7825 ай бұрын
Is morning bloating of stomach normal for this disease? I always wake up with a swollen sore abdomen in the morning and so much inflammation in the upper part of the stomach.
@MissionCure5 ай бұрын
Bloating can be a symptom of pancreatitis and EPI. However, something else may be going on. We recommend speaking with your doctor about any symptoms to better understand the underlying cause.
@silentgirltears7825 ай бұрын
What about absorbing medications like paracetamol, fexofenadine, antidepressants, gabapentin etc. Do these absorbs like normal or do these not work as effectively without the enzymes?
@MissionCure5 ай бұрын
Chronic pancreatitis and EPI can affect how well other medications are absorbed by your body. We recommend talking to your doctor about the specific medications you take and whether they should be taken with enzymes during meal time.
@silentgirltears7825 ай бұрын
Dr is there an enzyme available in the uk for Muslims or Jews who do not want to use the porcine version of enzymes?
@ShahiD-tb3ni5 ай бұрын
unfortunately there is no other options available
@shawnleebryan5 ай бұрын
I'm Muslim, and my doctor says other options are ineffective. There's a fatwa allowing porcine products for medications, and Allah knows best.
@MissionCure5 ай бұрын
Unfortunately, there are no vegan pancreatic enzymes at this time.
Пікірлер
Ive been taking Bile capsules and Papaya Emzymes
What do the bile capsules do, or help with?
Brilliant!!! What ive been looking for. Your guest is a gem❤❤
We're so glad it was helpful!
Can taking too many enzyme capsules cause constipation
Thank you for highlighting this area! There are few doctors that really understand the impact of EPI. Dr. Freedman also has an in depth article on Exocrine Pancreatic Insufficiency written with Dr. Struyvenberg that anyone with EPI should read. Another really helpful resource was the book Primal Pancreas.
I was diagnosed with EPI after a low fecal elastase test (72) last year, and I have been on PERT since then. I had been suffering from chronic IBS, diarrhea, weight loss, bloating, abdominal pain, and the PERT (Zenpep) seems to be helping with these symptoms, although I still have trouble maintaining weight and have occasional abdominal pain in the right side of my abdomen, below the rib cage and above the navel. I recently had my elastase retested, and my numbers are now above 400. My question is: was I misdiagnosed due to the poor stool quality of the first test, or can I still have EPI even with elastase numbers in the normal range? I've had multiple CTs, an abdominal ultrasound, PET scans and an MRI. No abnormalities were found. I plan to stay on PERT, but I'd sure like to know the hows and whys of my condition. My PHP was unaware of EPI until my case.
thank you man
Well Explained Mam, I am suffering from CCP along with Type 3c Diabeteis for 20 years. Excellent Presentation about Pancreatitis
We're glad you found this webinar informative!
Salam! I am from Lahore, Pakistan. I have been a patient of chronic pancreatitis for the past 16 years due to pancreatic divisum. Multiple endoscopic procedures like EUS, Gastroscopy, ERCP with sphincterotomy and stenting has been done. My gallbladder is surgically removed through laproscopy in 2017 but still there is no pain relief. Now almost 5 months ago the celiac block was done in PKLI hospital, Lahore. In this duration of 5 months i am feeling better because of pain relief but now my pain started again from last 10 days. I am totally exhausted and frustrated from life due to the constant severe abdominal pain. I am using strong opioids painkillers such as toradol, tramadol, nelbuphine and even morphine but there is no pain relief even for a micro second. I am always screaming and crying due to the pain severity. Sometimes, i thought about suicide because i have no more potential to bear this severe abdominal pain of chronic pancreatitis. Doctors advised me to go for a Whipple Surgery with Total Pancreatectomy but they said there is a lot of death risk and we cannot guarantee you the pain relief even after Whipple Surgery with Total Pancreatectomy due to this i am confused about the Whipple Surgery with Total Pancreatectomy. If you have a complete cure and better/definite treatment for this dreadful disease then please help me. My WhatsApp Num +92332-4779047 Email address : [email protected]
I have a 5y old son with severe EPI. He weighs 13kgs and is sevely disabled. What dosage applies in his case? Or does weight not matter?
We're sorry to hear about your son's severe EPI. The appropriate dosage of pancreatic enzymes often depends on both age and weight. It’s crucial to work with a pancreatic specialist who can tailor the treatment to your son's specific needs. Here are some resources that might help: PERT Dosing Guidelines: For detailed information on dosing guidelines based on age and weight, please visit our webpage: mission-cure.org/pancreatic-enzyme-replacement-therapy/ Managing EPI: Learn more about managing Exocrine Pancreatic Insufficiency (EPI) here: mission-cure.org/complications-of-chronic-pancreatitis/exocrine-pancreatic-insufficiency/ We highly recommend working closely with a pancreatic specialist to ensure your son gets the right dosage and to monitor his progress. They can provide the best advice and adjustments needed for his condition.
Wish my specialist was so informative
We are glad you found our resource informative!
Im type 3c lost most of my pancreas to goldstones for the pancreas tissue left 17 years ago now
What about the cholesterol medicine cousin pancreas!! Now what
Thanks for your lecture. I’m amazed how few doctors understand this disease, but most are happy to push drugs that they have limited experience with and not sure of the efficacy. Seems like the cure is available, but there’s no money to be made from it. You have low views so you’re on to something!
I would suggest getting arms xrayed. That is how I found out and it’s an early sign.
We're glad to hear that it was caught early!
Thanks so much for uploading/making this! I got out of hospital today, diagnosed with acute pancreatitis a couple months back and now its chronic with some necrosis. This has helped me feel reassured and your website is amazing, so much great information! I learned way more in this video than over 2 weeks in hospital, really appreciate it. I'm going to try to come back to this video once a year to comment :)
We're so glad the video and our website have been helpful and reassuring!
Hello there,I’m diagnosed with severe EPI , gastronologist never looked in to the cause I have pain on my left med back, and abdominal pain and gastrointestinal issues,would I qualify for clinical trials
For a thorough evaluation of your severe EPI and related symptoms, we recommend consulting with a pancreas specialist or a gastroenterologist who specializes in pancreatic conditions. They can help determine the underlying cause of your pain and gastrointestinal issues. To participate in clinical trials, a detailed diagnosis is typically necessary to assess whether you meet the eligibility criteria. You might find our diagnosis toolkit(mission-cure.org/pancreatitis-diagnosis-toolkit/) and diagnosis webinar (kzread.info/dash/bejne/Y6dk2q2PdLueobw.html) helpful as you seek further evaluation.
@@MissionCure i have chronic pancreatitis and epi and my weight is constantly decreasing.in april 2024 iwas 39 kg..in 2022 i was 53. my doctor gave ct scan and bllod test that appears normal but have stone and mpd in head. He said i will not intervene it right now.. he said i think u have bacterial overgrowth which is quite common in chronic pancreatitis patients. So he gave me antibiotic (rifagut) and normaxin..and creon 25k three times a day..my epi level is 4..i gained weight in this two month but only 1 kg..can you please help me how can i gain weight and is this a severe problem?
Best video on epi on KZread. Concise and detailed
Thank you! We're glad you found this EPI video helpful.💙
Can e.p.i cause dry skin like eczema i have floating oily stools and do local gp test for epi pluss ive realised enzymes over the counter are not strong enough which ones would u recommend?
Hi there! Exocrine Pancreatic Insufficiency (EPI) can cause vitamin and mineral deficiencies, which may affect your skin and hair, sometimes resulting in conditions like dry skin or eczema. Floating, oily stools are a common symptom of EPI. For testing, it’s best to consult with a specialist rather than relying solely on a general practitioner (GP). They can perform specific tests for EPI, such as a fecal elastase test. Over-the-counter enzymes are often not strong enough. We recommend looking into FDA-approved PERT brands, which you can find on our website: EPI Webpage: mission-cure.org/complications-of-chronic-pancreatitis/exocrine-pancreatic-insufficiency/ PERT Webpage: mission-cure.org/managing-pancreatitis/pancreatic-enzyme-replacement-therapy/ For more detailed information, check out our EPI playlist and our vitamin and mineral deficiency videos: EPI Playlist: kzread.info/head/PLJXha4Nvx8NJRu03C4kOj3CyoqjvB_Q6u&feature=shared Nutrition & Vitamin and Mineral Deficiency Videos: kzread.info/head/PLJXha4Nvx8NIxUzyrWc8ec0plt44vpMo4&feature=shared
The prescribed pancreas enzymes im taking are creating pancreatitis.
We're sorry to hear that the prescribed pancreatic enzymes are causing you discomfort. It's important to address this with your healthcare provider to ensure you get the right treatment without adverse effects. Here are some points to consider: FDA-Approved PERT: Pancreatic Enzyme Replacement Therapy (PERT) is FDA-approved and should be prescribed by a healthcare provider, rather than over-the-counter supplements, to ensure proper dosage and effectiveness. Side Effects: PERT can have side effects, and it’s essential to monitor how your body reacts. Discuss any adverse reactions with your doctor to adjust the treatment as needed. EPI Playlist: We have a playlist with videos that provide insights into managing Exocrine Pancreatic Insufficiency (EPI) and using PERT effectively. You can find it here: kzread.info/head/PLJXha4Nvx8NJRu03C4kOj3CyoqjvB_Q6u&feature=shared Consult a Specialist: Working with a pancreatic specialist can help you find the right fit for your condition and manage any complications. They can provide personalized advice and adjustments to your treatment plan.
I never have a formed stool. How to test?
Stool test must be a formed stool or it will always come back low.
To test for Exocrine Pancreatic Insufficiency (EPI), it’s best to consult with a doctor. They might recommend a fecal elastase test and possibly a 72-hour fecal fat test. Additionally, blood tests for vitamin deficiencies and imaging studies like CT or MRI scans of the pancreas might be needed. A specialist can help determine if your loose stools are due to EPI or another underlying cause. Sometimes, they may treat it with Pancreatic Enzyme Replacement Therapy (PERT) to observe the response and then order a test on a formed stool. Hope this helps!
Hi doctor do loss of. Normal pancreatic lobulations means auto immune pancreatitis??
Loss of normal pancreatic lobulations isn't specific to autoimmune pancreatitis (AIP). This change can also be seen in other conditions affecting the pancreas, including various types of pancreatitis. A definitive diagnosis should be made by your healthcare provider and a pancreas specialist, who will consider your clinical symptoms, lab results, and imaging studies. If you're in the US, we recommend consulting with one of the experts listed in our autoimmune pancreatitis blog. They can provide more personalized advice and help address your health needs and queries. AIP Blog: mission-cure.org/autoimmune-pancreatitis-symptoms-diagnosis-and-treatment/
Is there any help for EPI in the pipeline?
There are ongoing developments in the Pancreatic Enzyme Replacement Therapy (PERT) space, with several companies working on creating more efficient and effective products to help manage EPI better.
Very informative doctor. I am diagnosed with chronic pancreatitis since when I was 13 and now I am 26 and from last few month I am recovered from stetorreah but my farts are so smelly and this exists even I don’t take a meal…. Can you help me here please?
Hi there! We're sorry to hear about the difficulties you're experiencing. Many patients with chronic pancreatitis face similar challenges. Our holiday tips video provides advice on managing such conditions when you're out in public, which you might find helpful. Additionally, we recommend working with a gastroenterologist to rule out any digestion-related conditions that could be causing the issue. Maintaining a well-balanced diet with a good amount of fiber can also be beneficial. For more detailed tips, please check out our nutrition webinar. Wishing you the best! Holiday Tips Video: instagram.com/reel/C1Hh4iqNaR7/?igsh=MzRlODBiNWFlZA== Nutrition Webinar: kzread.info/dash/bejne/m4tnsc6MYbS2l5M.html
Pancreatitis and Covid... there may be indications that the spike protein can cause IGG4 which in turn might have a relation with AIP. Is this true and being researched?
There is some research exploring the impact of COVID-19 on various bodily functions, including the pancreas. While there are indications that the virus could affect pancreatic functions, conclusive evidence linking the spike protein specifically to IgG4 production, which is associated with AIP, is still being researched. For a deeper understanding of AIP and its association with IgG4, you may find our video on AIP symptoms, diagnosis, and treatment helpful: mission-cure.org/autoimmune-pancreatitis-symptoms-diagnosis-and-treatment/ Additionally, here are a couple of studies that discuss pancreatic injuries related to COVID-19: www.ncbi.nlm.nih.gov/pmc/articles/PMC9021704/ www.ncbi.nlm.nih.gov/pmc/articles/PMC7118654/ www.mdpi.com/1422-0067/23/2/864 These resources might provide further information that you can discuss with your healthcare provider.
@@MissionCure is it common to have bacterial overgrowth as a chronic pancreatitis patient.. my epi is 4 and recently i lost 10kg after ct scan of pancreas it seems normal but according to my loosing fat and body mass doctor said may be you have bacterial overgrowth qs symptoms indicate towards it..i am not diabetic..i am taking rifagut400..can it will be difficult to gain weight agai ? Plz explain
And yes i am taking creon 25k 3 times a day only. Pls make a video on it
@@chetnajaiswal75 I benefitted a lot from fasting. It seems counterintuitive when you are losing weight, but it really helped to restore my gut microbiome. After that I started to gain weight and symptoms like bloating disappeared. Now I fast every time I feel it is necessary. I guess that, because of malfunctioning pancreas, bad bacteria (and bacteria in the wrong place in your gut) get a chance to develop. Despite supplementing pancreatic enzymes. Fasting may restore balance. Consult your doctor to see if this might be an option for you.
I suffered for 22 years. So grateful for enzymes❤ This video sheds a lot of light on how this happened.
He just gave me my diagnosis within the first minute of the video!
Is osteoporotic bone loss compounded when chronic pancreatitis (EPI), primary hyperparathyroidism, renal insufficiency, and total gastrectomy (secondary to NET) are experienced simultaneously? Do you think these comorbidities are connected despite a healthy lifestyle with good nutrition?
A healthy lifestyle and good nutrition are definitely factors that will positively influence overall health and well-being, but diseases, including Chronic Pancreatitis, have multiple causes. A progressive disease like CP represents an increased risk of EPI, bone disease, and other possible co-morbidities. For more detailed information about the complications associated with chronic pancreatitis, please visit our resource page: mission-cure.org/complications-of-chronic-pancreatitis/ We highly recommend consulting with a pancreas specialist and assembling a multidisciplinary care team to tailor the treatment to your specific needs.
I have chronic pancreatitis and epi and i was 50 kg in 2022 but since 2023 i lost 10kg weight now i am 40kg.. my epi is 3.5( fecal elastase done on sep 2023)..i am currently on creon 40k three times a day..please help me..why it is happening what should i do.? How i can gain weight? My doctor is not taking my health issues seriously
We're sorry to hear about your struggles with chronic pancreatitis and EPI. For more information, please visit our pages on Exocrine Pancreatic Insufficiency (EPI) [mission-cure.org/complications-of-chronic-pancreatitis/exocrine-pancreatic-insufficiency/ ] and Pancreatic Enzyme Replacement Therapy (PERT) [mission-cure.org/managing-pancreatitis/pancreatic-enzyme-replacement-therapy/ ]. These resources can help you discuss your care more effectively with your doctor. We also recommend exploring the FDA dosage guidelines on the PERT page and watching our videos on EPI management [kzread.info/dash/bejne/a3el0JWug9upgtY.htmlfeature=shared ] to see if your current treatment protocol aligns with recommended practices.
does bicarbonate tablet taken with enzymes will help?
It's important to consult with your healthcare provider or gastroenterologist to find the option that works best for you.
What if I have tried so many pancreatic porcine enzymes and I have side effects from them and the only options are now OTC pancreatic vegan enzymes ? Also is this normal ( I have severe EPI lab 86 and chronic pancreatitis ) that before diagnosis I did not have runny stools but just constipation won’t enzymes constipate me even more ?
We encourage you to visit our PERT webpage (mission-cure.org/managing-pancreatitis/pancreatic-enzyme-replacement-therapy/ ) to learn more about enzyme therapy options. Currently, there are no FDA-approved vegan enzymes available for treating EPI. It's important to always consult with your healthcare provider or gastroenterologist to explore the most suitable and effective treatment options for your specific condition.
Thank you God bless
So no clinical trials 2 years on?
Neither of these projects is in clinical trials, unfortunately, but there is the trial of paricalcitol for chronic pancreatitis, a few other studies, and 2 more recurrent acute and chronic pancreatitis therapy trials starting soon. Check our website, mission-cure.org/clinical-trials-and-strategy/our-cure-strategy/pancreatitis-clinical-trials/.
My stomach is in pain after takingEmzymes
We're sorry to hear that you’re experiencing stomach pain after taking enzymes. Some patients do report side effects with PERT (Pancreatic Enzyme Replacement Therapy). It’s important to work with your doctor to pinpoint the cause of the pain and see if it's related to your PERT therapy. They might suggest trying different digestive enzymes. You can also find more information on PERT dosage and possible side effects on our PERT webpage: mission-cure.org/managing-pancreatitis/pancreatic-enzyme-replacement-therapy/ Hope you feel better soon!
i'm 28 nd taking Kreon 10000 2 capsules per meal
why has this become so common recently? could this be related to Covid or to Covid vaccines?
There is some research exploring the impact of COVID-19 on various bodily functions, including the pancreas. While there are indications that the virus could affect pancreatic functions, conclusive evidence is still being researched.
I had developed severe Exocrine Pancreatic Insufficiency post Covid. I have pain in the L and R upper quadrant. Pls advise which tests I need to diagnose chronic pancreatitis? Thanks 🙏
We are sorry to hear of your symptoms and the diagnosis of EPI. Please visit our webpage where causes and symptoms of CP have been detailed, linked here: mission-cure.org/chronic-pancreatitis/ You can also have a look at our diagnosis webinar and toolkit to help you navigate your conversation with your doctor linked below: Toolkit: mission-cure.org/pancreatitis-diagnosis-toolkit/ Diagnosis webinar: mission-cure.org/pancreatitis-diagnosis/
I’ve been STARVING for this information ever since diagnosis (while hospitalized for malnutrition 😬)!
22:32 has it occured to anyone that possibly because people are following low fat diets that its creating this problem? I thought we were supposed to eat fatty fish and butter on a regular basis? Olive oil and lamb? Isn't that what the Mediterranean diet is? If our gallbladder isn't being used often enough, it seems like it gets clogged, lazy and malfunctions.
Thanks for your input. Pancreatitis has various causes, including gallstones. As our expert highlights, there's no one-size-fits-all diet recommendation for all pancreatitis patients. Clinical research evidence suggests a positive relationship between fat content and exacerbation of symptoms in some patients. We always recommend patients work with their doctors and dietitians to find protocols that suit their specific needs, which are multifactorial. You can explore our nutrition webpage for more information on the topic:mission-cure.org/managing-pancreatitis/nutrition-for-chronic-pancreatitis/
I just started Creon Dr 2400 units
My daughter was inpatient and they determined acute pancreatitis. My prideful MIL kept from us the fact that her mother died from pancreatic cancer. It’s truly sad when family cares more about pride than their own grandchild.
I learned more in this one video than I learned during a recent admission in hospital x 1 week.
Thank you. I'm glad you found it useful. I hope you've subscribed to our channel. Megan
I got it from immunotherapy! I don’t see much on this topic. The pain was awful. It involves pancreas only and comes back when I wean off prednisone. No elevated igg4.
Hello @mpoharper, we are sorry to hear this. We raised your query with our expert and have some feedback and additional info. Could you write to us at [email protected] and mention your comment so we can respond with more details? Thank you!
@@MissionCuresure
Hi. , can the loss of normal pancreatic lobulations indicates auto immune pancreatitis?
@@HarpreetKaur-ti2xp I don’t know. My gastrointestinal doctor was useless in this regard.
That’s unfortunate, they let people suffer like this
I developed pancreatitis from checkpoint inhibitors. Adding digestive enzymes really has helped reduce prednisone. I will hopefully get off prednisone all together!
I have been off prednisone for a month and pancreas appears to be doing well! Enzymes made a big difference!
Was your daughter a carrier of CFTR or did she have CFTR? I am a carrier of CFTR, but don't have CFTR. I have Pancreatitis and am on creon. Within the last two years I lost two brothers to pancreatic cancer! Brothers age were 55 and 57. Way too young to die! Doctors never did figure out the cause of the disease!
We are so sorry to hear about the loss of your brothers. Here are some resources that might be helpful: Learn more about the role genetics play in pancreatitis: mission-cure.org/genetics-and-pancreatitis/ Our Genetics in Pancreatitis Toolkit provides valuable information: mission-cure.org/pancreatitis-genetic-testing/ Seeking support from a pancreatitis specialist can also be crucial in managing your disease effectively.
I am in unbearable pain. Been in 4x. They put me on oxys 10 instead of 7.5 I would just love my pain to let up. It's horrible
We're really sorry to hear this. Take care 💙
Hey I hear you, here in Michigan I've been to hospital a few times now been back and forth to the doctor for years. Not once given pain killers. 😢 yet I've also never been a opioid or even a drug user! I have no history of drug abuse yet my doctor never talks about using even a low dose painkiller like a hydro or something. I'm just surprised it depends where you go in the country for sure! Good luck with your struggle keep going don't give up
Recently diagnosed with this but omg the medicine is $900/month with insurance! I cant afford it! :(
Creon has a assistance program which include vitamin and mineral supplements.
@@dancethenightaway70 omg THANK YOU!!!
You can find information on PERT savings programs here: mission-cure.org/pancreatitis-resources-and-support/ Hope this helps!
Do you think there is a correlation between CF carriers and acute to chronic pancreatitis?
Hi Ashley! Yes, the CF (CFTR) gene can play a role in causing chronic pancreatitis. For more information on CFTR and genetics and pancreatitis, visit: mission-cure.org/chronic-pancreatitis/genetics-and-pancreatitis/
Is morning bloating of stomach normal for this disease? I always wake up with a swollen sore abdomen in the morning and so much inflammation in the upper part of the stomach.
Bloating can be a symptom of pancreatitis and EPI. However, something else may be going on. We recommend speaking with your doctor about any symptoms to better understand the underlying cause.
What about absorbing medications like paracetamol, fexofenadine, antidepressants, gabapentin etc. Do these absorbs like normal or do these not work as effectively without the enzymes?
Chronic pancreatitis and EPI can affect how well other medications are absorbed by your body. We recommend talking to your doctor about the specific medications you take and whether they should be taken with enzymes during meal time.
Dr is there an enzyme available in the uk for Muslims or Jews who do not want to use the porcine version of enzymes?
unfortunately there is no other options available
I'm Muslim, and my doctor says other options are ineffective. There's a fatwa allowing porcine products for medications, and Allah knows best.
Unfortunately, there are no vegan pancreatic enzymes at this time.