my dad died from pancreatic cancer, and i had idiopathic chronic pancreatitis; i didn't have the gene like the docs thought; i had the tpiat procedure at musc. dr. morgan said i had the worst pancreas she has ever seen. this is great because c.p. is an awful disease. i am one year post op and finally pain free. my islet cells are functioning pretty well. i take a low dose long lasting insulin in the morning and that's it.

@gtisch183

Жыл бұрын

Hi Seth, do you recommend getting diagnosed at MUSC?

Is there any help for EPI in the pipeline?

@MissionCure

Ай бұрын

There are ongoing developments in the Pancreatic Enzyme Replacement Therapy (PERT) space, with several companies working on creating more efficient and effective products to help manage EPI better.

So no clinical trials 2 years on?

@MissionCure

4 ай бұрын

Neither of these projects is in clinical trials, unfortunately, but there is the trial of paricalcitol for chronic pancreatitis, a few other studies, and 2 more recurrent acute and chronic pancreatitis therapy trials starting soon. Check our website, mission-cure.org/clinical-trials-and-strategy/our-cure-strategy/pancreatitis-clinical-trials/.

In how many years we can expect the treatment for genetic pancreatitis by mutation in spink-1 n ctrc both heterozygous to come up

@MissionCure

Жыл бұрын

Our goal is to have an effective treatment for CP in 10 years or less! Spink-1 and other genes are a part of our therapeutic pipeline, and are currently in preclinical research.

@santanunayak4043

10 ай бұрын

Bro I have also spink 1 and ctsb mutation and have recurrent acute pancreatitis

Where is this clinical trial being performed? I will volunteer.

@MissionCure

2 жыл бұрын

Thanks for your interest, Dawn. The trial has not started yet and we don't know exactly where it will be. We have a page on our website dedicated to publicizing clinical trials for pancreatitis and we will certainly post it there, as well as on our social media. Stay tuned!

@vijaysingh-zg6wp

2 жыл бұрын

This things wil take another 100 years , they just speak y it is taking so much time to cure diabetis , it's the drug mafia who don't it , as it wil close down most of the pharmaceutical companies ..

@MissionCure

4 ай бұрын

Neither of these projects is in clinical trials yet, unfortunately, but there is the trial of paricalcitol for chronic pancreatitis, a few other studies, and 2 more recurrent acute and chronic pancreatitis therapy trials starting soon. Check our website, mission-cure.org/clinical-trials-and-strategy/our-cure-strategy/pancreatitis-clinical-trials/.

How can we be part of trial?

@MissionCure

2 жыл бұрын

Thanks for your interest, Naomi. The trial has not started yet and we don't know exactly where it will be. We have a page on our website dedicated to publicizing clinical trials for pancreatitis and we will certainly post it there, as well as on our social media. Stay tuned!

Can these stem cells regenerate the damaged pancreas?

@MissionCure

2 жыл бұрын

Thank you for this great question, David. The theoretical answer is yes, stem cells could be used to regenerate the entire pancreas. Unfortunately, that is beyond the current state of stem cell science. RMS is focused on the challenge of just replacing the beta cells. In the distant future, it might be possible to generate an entire organ, but for now, we are limited to replacing one cell type at a time.

@davidsheridan1314

2 жыл бұрын

Thank you, what do you think of the regeneration center in Thailand?

Was your daughter a carrier of CFTR or did she have CFTR? I am a carrier of CFTR, but don't have CFTR. I have Pancreatitis and am on creon. Within the last two years I lost two brothers to pancreatic cancer! Brothers age were 55 and 57. Way too young to die! Doctors never did figure out the cause of the disease!

@MissionCure

22 күн бұрын

We are so sorry to hear about the loss of your brothers. Here are some resources that might be helpful: Learn more about the role genetics play in pancreatitis: mission-cure.org/genetics-and-pancreatitis/ Our Genetics in Pancreatitis Toolkit provides valuable information: mission-cure.org/pancreatitis-genetic-testing/ Seeking support from a pancreatitis specialist can also be crucial in managing your disease effectively.