Why Psychedelics Can Change The World - Prof David Nutt

Ғылым және технология

“The last 55 years of banning psychedelics is the worst censorship of research in the history of the world.” -Professor David Nutt
Professor David Nutt is THE go-to expert on psychedelics. His charity Drug Science is on a mission to break the stigma around hallucinogenic drugs, and inform the public on the real science behind their effects.
In this episode I ask David how drugs like magic mushrooms, MDMA, cannabis and Ketamine are able to treat brain disorders, like depression, so effectively - and why we’ve been led to fear these drugs.
Stay tuned to find out:
The truth about why psychedelics were banned in the first place
How safe these drugs are in both a medical and recreational setting
Whether human evolution was driven, in-part, by psilocybin mushrooms
About the most recent science and trials
Myths and misinformation surrounding their use
How soon we might see the legalisation of psychedelics
Highlights
0:00 Intro
1:41 50 years of censorship
7:12 Emerging research
10:24 Safety of psychedelics
12:47 The stoned ape theory
19:12 How psychedelics treat depression
22:48 When will they be legal?
25:38 Physiological changes in the brain during use
29:54 Psychedelics versus conventional methods
32:47 Recreational use
35:47 Microdosing
39:06 Enduring benefits of psychedelics
42:26 Misinformation
44:05 Treating addiction
47:13 Future legalisation
Connect with me:
TikTok: / drkaranrajan
Instagram: / dr.karanr
For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: geni.us/DrKaranBook
An OG Podcasts production.

Пікірлер: 208

  • @juansantos8347
    @juansantos8347Ай бұрын

    Psychedelics/psilocybin containing mushroom have proven a to be a reliable cure for depression, anxiety, ADHD, bipolar, OCD, insomnia, and other related disorders. Saved my life honestly.

  • @brittney2509

    @brittney2509

    Ай бұрын

    I can't wait tell they decriminalize magic mushrooms in Illinois. This has helped me more than any antidepressant ever has.

  • @LindseyHernandez-xe7gb

    @LindseyHernandez-xe7gb

    Ай бұрын

    Where do you fetch from?

  • @Mary-pb3ll

    @Mary-pb3ll

    Ай бұрын

    Dr.Pencemush10

  • @Mary-pb3ll

    @Mary-pb3ll

    Ай бұрын

    𝖎𝖓𝖘𝖙𝖆𝖌𝖗𝖆𝖒

  • @Vivian3464

    @Vivian3464

    Ай бұрын

    Taking shrooms was 100% one of the most important experiences in my life. Everything has changed since my trip - I perceive things differently.

  • @MrSteveishere
    @MrSteveishereАй бұрын

    I took a lot of LSD through the 1990's and unlike some people who claim that the odd dose of acid cured their depression taking LSD never cured my bouts of depression, if anything the comedowns from the trips made things worse for me, probably the returning back to the dreary reality of life at that time, depression is an illness that is so hard to treat, I never found anything that really worked for me, the therapy sessions were pretty much a joke and then we get those little pills that merely mask the symptoms but cause other problems for us, I hope that this research helps people get past the loneliness of depression..

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    You can't rely on a substance to cure your own mind's feelings. Only you really can. You have to be aware enough. You have to be accountable enough. If you are not willing to be self-aware of your own issues and aren't willing to take accountability for them, no amount of "medicine" will cure you. The only person who can cure yourself is yourself. It's your actions and thoughts that cause and cure depression.

  • @janeharry790
    @janeharry790Ай бұрын

    Psychedelics are just an exceptional mental health breakthrough. It's quite fascinating how effective they are against depression and anxiety. Saved my life.

  • @labandalatinband

    @labandalatinband

    Ай бұрын

    Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable s0urce here in Australia. Really need!

  • @Sami-cy4yj

    @Sami-cy4yj

    Ай бұрын

    Yes, Psychehubs. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.

  • @Minidjdj

    @Minidjdj

    Ай бұрын

    Is he on instagram?

  • @Sami-cy4yj

    @Sami-cy4yj

    Ай бұрын

    Yes he is. Psychehubs

  • @ugnoise

    @ugnoise

    Ай бұрын

    Microdosing helped me get out of the pit of my worst depressive episode, a three year long episode, enough to start working on my mental health.

  • @ryanpriye1402
    @ryanpriye1402Ай бұрын

    It’s always surprised me how the conservatives and the religious right are so okay with alcohol but not with psychedelics when they don’t do anywhere near the amount of harm that alcohol has been proven to do.

  • @naturally_rob

    @naturally_rob

    Ай бұрын

    I had access to the internet at a very young age and read quite a bit of stuff. I remember learning about prohibition in the states and then eventually the war on drugs. It has perplexed me since I was a kid; why substances that are on the whole way less harmful (though still harmful with improper use) and have less negative long-term effects illegal than those that are far more dangerous and yet legal.

  • @TheDude8008

    @TheDude8008

    Ай бұрын

    I dislike both, and while we're at it I hate tobacco, caffeine and carbonated drinks too

  • @wqiojekpldlknbwjklopiwojaslKZ

    @wqiojekpldlknbwjklopiwojaslKZ

    Ай бұрын

    nice broad generalization of traditional people by comparing them to people of the nixon and reagan era when people were swayed by gov psyops on the television

  • @ParrotPentester

    @ParrotPentester

    Ай бұрын

    Thankfully my religion is against alcohol and addictive unnecessary drugs too

  • @ab-js2gw

    @ab-js2gw

    Ай бұрын

    Don't expect logic from people who believe there is an imaginary guy in the sky who is very interested in what sexual activities they participate in and substances consume.

  • @arealhuman826
    @arealhuman826Ай бұрын

    I can attest to this. Psychedelics are not to be taken lightly, however, if done properly, it can lead to profound insight. I was 20 years old and I took a handful of mushrooms with friends in college. The entire experience can be very overwhelming at first, especially if youre going into it with the goal of "partying". Anyways, at the time, I was a borderline pathological liar. Saying anything and everything in a desperate need to be liked. Sometime during my psychedelic trip, I was made to fully realize that my lies are the reason why nobody liked me. If i just relax, enjoy myself and the life i live, that I would find happiness there. any therapist can tell you this. Psychedelics make you see and feel it in a way that resonates. I don't know. Psilocybin mushrooms did more for my mental health than any antidepressant or therapist ever could, and I only had to take them once.

  • @arealhuman826

    @arealhuman826

    Ай бұрын

    also, while mdma and cannabis can have hallicinogenic properties, i do not think they are powerful enough to have a proper "trip" where you meet your inner gods and demons and sort out who is who. also mdma has horrible side effects. i would personally recommend psilocybin mushrooms or ayahuasca. I have heard good things about LSD as well, however i know that a lot of street LSD is just research chemicals and thats very dangerous so I wouldnt recommend LSD personally.

  • @Eliqueme

    @Eliqueme

    Ай бұрын

    🙌🏽🙌🏽🙌🏽🙌🏽❤️❤️❤️❤️ Ahö , I can concur too 😊

  • @Bpaynee

    @Bpaynee

    Ай бұрын

    Whoa, fascinating story. Thanks for sharing!

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    I don't think psychedelics did this. You did this. You knew this deep down. The psychedelics likely brushed away all the debris from your mind to become aware of it, even though deep down you were aware of it and just didn't want to admit it. This won't help anyone if they don't already realize what's wrong. It's not a good thing to prescribe something based on personal experience with no extensive research into it. Like anything in this world, it will affect people differently from others. And they can still become addictive like any other drug or food. I wouldn't recommend it. Just watch in 10 years or more we'll likely have studies coming out about how they actually do harm when you're addicted to them. Advertising them as a depression cure is harmful as well because people will get addicted to them because they'll think their depression will go away. When there's so much more to them than just ingesting them.

  • @arealhuman826

    @arealhuman826

    Ай бұрын

    @@Jake38nine i can only speak for mushrooms, and im not prescribing anything. i made it clear i was just saying my experience and opinion, i thought. that being said, ayahuasca and mushrooms have been being since before history, i think the data is basically in by now.

  • @Tylervrooman
    @TylervroomanАй бұрын

    A good question is what haven't they lied about? Their credibility is gone. Especially on issues of war and peace. Thanks for the great videos and insights!

  • @toromothy
    @toromothyАй бұрын

    great to see this kind of content gaining more traction in the UK!!!!

  • @ClarkAfterDark1111
    @ClarkAfterDark1111Ай бұрын

    Not only is there huge potential for mental health but also physical. I had a bakers cyst in the knee for 3-4 months before it suddenly vanished in an Ayahuasca trip my first week in Peru.

  • @ClarkAfterDark1111

    @ClarkAfterDark1111

    Ай бұрын

    Ive also mitigated serious back issues, pain, pulled muscle, spasms with classic psychedelics with huge success

  • @ClarkAfterDark1111

    @ClarkAfterDark1111

    Ай бұрын

    theres also huge potential with headaches...cluster or migraine

  • @dozus35
    @dozus35Ай бұрын

    50 min feels like 5 min video , where u don't want it to end ❤

  • @DrKaran

    @DrKaran

    Ай бұрын

    That’s very pleasing to hear ! Thanks for watching and gotta some more interesting guests lined up this season!

  • @robertwilks-yk6hi

    @robertwilks-yk6hi

    Ай бұрын

    ​@DrKaran if you could get Dr Rick strassman that would be amazing, his book the spirit molecule is brilliant, all about the medical uses and tests for dmt.

  • @dozus35

    @dozus35

    Ай бұрын

    @@DrKaran exciting.

  • @DrMizanCoaching
    @DrMizanCoachingАй бұрын

    I was literally consulted today on a case of magic mushroom intoxication and this popped up on my feed! Just wanted to let you know Dr Karan that I've been following you for a while now and you significantly inspired me to start my own channel where I talk about the medicolegal aspects of medicine and the state of the US healthcare system. Would 100% be down to do a collab at some point if you are!

  • @_negentropy_
    @_negentropy_Ай бұрын

    Great interview! Very excited and hopeful that MDMA could potentially mitigate the psychopathology that arises from personality disorders. Thanks so much Dr. Karan!

  • @DrKaran

    @DrKaran

    Ай бұрын

    Welcome and thanks for watching!

  • @nikhiljagga771

    @nikhiljagga771

    Ай бұрын

    Fyi the FDA advisory panel rejects MDMA as a PTSD treatment. In a blow to advocates of psychedelics for mental health treatment, a panel of experts voted against recommending that the Food and Drug Administration approve MDMA to treat post-traumatic stress disorder. The panel raised concerns about the study conducted by Lykos Therapeutics, which is hoping to get the drug approved as the first-ever sanctioned psychedelic treatment, questioning the data and potential risks. The FDA does not have to follow the panel’s recommendation, but it usually does. A final decision is expected in August.

  • @LegaliseFinland
    @LegaliseFinlandАй бұрын

    Great to see this topic getting the attention it deserves.

  • @DrKaran

    @DrKaran

    Ай бұрын

    Trying to de stigmatise the topic!

  • @Nick-tc7oz
    @Nick-tc7ozАй бұрын

    I've listened to dozens of interviews with Prof. Nutt and, can I say Dr Karan, these are some of the most articulate and insightful questions I've seen posed to him. You show real insight, and give him a great platform to get deep into all of the major and most important issues regarding psychedelic research - well done 👏

  • @bettystouffer6012
    @bettystouffer6012Ай бұрын

    Outstanding post!

  • @ClarkAfterDark1111
    @ClarkAfterDark1111Ай бұрын

    Great to see you speaking on this

  • @rawadyonus381
    @rawadyonus38129 күн бұрын

    A great interview, indeed. I love your questions, Dr.

  • @john-wiggains
    @john-wiggains23 күн бұрын

    More of this please!!!

  • @silverghostcat1924
    @silverghostcat1924Ай бұрын

    Basically the "war on drugs" makes revenue for cities and counties. Marijuana and heroin were made illegal as a way to control the anti-war hippies (marijuana) and blacks (heroin). Nixon couldn't make the people illegal but, by associating these substances with them and making those illegal, the government had a means to control the groups it found problematic.

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    You don't need drugs to be anti-war. Lmao xD I don't take any drugs and I'm anti-war and anti-establishment and anti-governemnt and anti-monetization of things that can be harmful. I'm pro-skepticism of literally almost everything. I promote skepticism of everyone and everything. I'm not gonna believe something without years of experience. And I doubt these people had enough years to actually study these drugs and how it affects people considering the drugs were banned and even a scientist would get in trouble for studying it. Marijauna is coming out as being a cause of psychosis now. Relying on drugs is not going to help your brain. That's just the plain reality of that. It won't cure your depression or anxiety. Depression and anxiety are not exactly things you can cure period. They're natural hormones every animal feels. Anxiety especially is our natural fight or flight mechanism. You get rid of anxiety in humans and you essentially cease them from being able to survive in a way. And giving people disability money for it may only be enabling it instead of having them overcome it and fight through it.

  • @fourtyseven47572

    @fourtyseven47572

    Ай бұрын

    ​@@Jake38nine Cannabis doesnt cause pyschosis

  • @AlexandriaTheGreat
    @AlexandriaTheGreatАй бұрын

    Excellent interview. Great questions and discussion. Thank you.

  • @DrKaran

    @DrKaran

    Ай бұрын

    Glad you enjoyed!

  • @craigofcimmeria5215
    @craigofcimmeria5215Ай бұрын

    Brilliant podcast, long time fan of Professor Nutt's work. Can only say Psychadellics changed my life and helped me with severe long term depression. Hes right, it's not something you can do for fun or often, it's not always a silly fun time at all.

  • @patriciaZMarie2867
    @patriciaZMarie2867Ай бұрын

    Same as the treatment for opiate addiction! Is every difficult for regular doctors to prescribe it outside of specialized clinic asking with strict therapy making hard for those people to to aquire and maintain jobs because of the strictness of the treatment plan

  • @ab-js2gw
    @ab-js2gwАй бұрын

    Unfortunately lawmakers are absolutely useless at taking responsibility and will not admit "war on drugs" is completely disaster and waits of taxpayers money.

  • @ItsTripTips
    @ItsTripTipsАй бұрын

    Awesome!

  • @anonymoushawk962
    @anonymoushawk96217 күн бұрын

    47:49 DUDE FINALLY A GUY WITH SOME SENSE… regulated access would be ground breaking. A few trips a year at maximum access. I agree with this 100%.

  • @alastairbowie
    @alastairbowieАй бұрын

    Cool video... Thank you for uploading it! Hearing about having to do the microdosing study in hospitals only makes me think of the best way to derive therapeutic value from Psychedelics... In all seriousness I believe a phat party where you are on Psychedelics with loved ones that is joyous and celebratory all up is much more therapeutic and healing than having to deal with a stern bloke with a clipboard in a drab and sterile environment like a hospital who essentially has the Psychological frame that he is superior to you (as an expert) and you are a broken being with a damaged or malfunctioning biology.... #Hope and #progress...

  • @john-wiggains
    @john-wiggains23 күн бұрын

    It comes back because the memories likely haven’t been processed. Until they’re properly processed or turned down the intensity of the memory, they may reexperience the trauma hundreds of times over and over.

  • @anonymoushawk962
    @anonymoushawk96217 күн бұрын

    Psychedelics are so powerful when the user experiences “realizations”. That feeling can last with you for life. Powerful metaphors and metaphysical thoughts lead to this… this “woke” feeling is extremely potent. And I feel it can shock people out of negative thought patterns. We have to facilitate “realizations” in the user in order for it to have meaningful change. No only that but also support and the down to earth conversations that make the user more open to acceptance and looking at things as “glass half full” rather than empty.

  • @anned6913
    @anned6913Ай бұрын

    Brilliant. Thank you .

  • @DrKaran

    @DrKaran

    Ай бұрын

    Welcome!

  • @alyssaoconnor
    @alyssaoconnorАй бұрын

    An Autistic friend had tried all of the family groups of Antidepressants trying to treat depression and extreme anxiety for decades with no or worse results, MDNA however had a profound positive effect for him. Hopefully studies on this will be done soon and be available as a treatment method.

  • @missbettyboop2509
    @missbettyboop2509Ай бұрын

    Thank you❤❤❤❤🎉🎉🎉

  • @DrKaran

    @DrKaran

    Ай бұрын

    You are very welcome!

  • @theprodigalson4003
    @theprodigalson4003Ай бұрын

    Hearing this from you. I’m going into it within the next 2 months. I’ve struggled with chronic sleep for the last 7 years of my life. I’m going into the universe now. No more suffering. Not without me trying to do soemthing about it See you all later

  • @nikhiljagga771
    @nikhiljagga771Ай бұрын

    UPDATE (June 4): FDA advisory panel rejects MDMA as a PTSD treatment. In a blow to advocates of psychedelics for mental health treatment, a panel of experts voted against recommending that the Food and Drug Administration approve MDMA to treat post-traumatic stress disorder. The panel raised concerns about the study conducted by Lykos Therapeutics, which is hoping to get the drug approved as the first-ever sanctioned psychedelic treatment, questioning the data and potential risks. The FDA does not have to follow the panel’s recommendation, but it usually does. A final decision is expected in August.

  • @z3lda808
    @z3lda808Ай бұрын

    If love to listen to you speak with Prof Felice Jacka from Deakin Uni's Food & Mood Centre

  • @dantemedici8179
    @dantemedici8179Ай бұрын

    I’ve taken it all mate

  • @mellie4174
    @mellie4174Ай бұрын

    I just don't see how you can make an argument against the same access to psychedelics as alcohol when they are vastly less harmful than alcohol.

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    I'd argue they are equally harmful depending upon usage.

  • @MrDanmjack
    @MrDanmjackАй бұрын

    The drug science podcast is excellent. I suggest you all listen to it.

  • @Schnellanie
    @SchnellanieАй бұрын

    I have cancer and got my terminal diagnosis exactly one year ago. After an integrative doctor literally brought me back from the dead, a friend of mine took me on a journey. It was hands down one of the best things I've ever done in my life. It took the edge off, helped with anxiety, and I resolved more trauma with one session than therapy could've done in a year. Highly recommend!

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    If you had done the drugs without a year of therapy, I doubt it would've helped you at all. For you to solve problems you must be aware of them in the first place. Therapy surfaced those problems over a year for you and the drugs washed away all of the debris for you to see it clearly and be more aware of it. If you took them without therapy, I highly doubt your symptoms would vanish. So it is NOT safe to recommend without a fully disclosed study on multiple people who take the drug before and after therapy, which would take years because therapy takes years. But the main part of the study would be to see if the results are the same with and without therapy. But I highly doubt it. It also relies on the honesty of the patient. There's so many variables that nobody can control all of them, thus generally recommending a drug is not advised. We can study how something affects pain or illness because it affects body parts and organs that only have one job. Whereas the brain can literally psyche yourself out and gas light yourself. If you really tried, you could convince yourself that you're a rabbit. That's how powerful and unpredictable the brain is. The brain evolves much faster as well. What could help us adults now may not help our grandchildren or great grandchildren because the brain evolves and adapts so often to its surroundings, thus trauma, suffering, trials, and tribulations will always exist. There will never be a cure for ailments of the brain. It's just scientifically and logically impossible because the brain changes rapidly.

  • @fourtyseven47572

    @fourtyseven47572

    Ай бұрын

    ​@@Jake38nine you could also say that therapy without the pysches wouldve done nothing

  • @Schnellanie

    @Schnellanie

    26 күн бұрын

    ​@@Jake38nineI never did a year of therapy, I only had a few sessions years ago that's why I said it helped me more than a year of therapy could've. I also think set, setting, and Intent is extremely important and most people don't really wanna work on their stuff, I was ready and excited to change my life for the better...

  • @mellie4174
    @mellie4174Ай бұрын

    Antidepressants may be effective but they have so many horrible side effects! The nausea, the brain zaps, impotence, elimination of libido, increased depression, vomiting, diarrhea, weight gain and indirectly diabetes.They are not the answer. They're the best answer that we have right now. But they're really pretty terrible.

  • @limbeboy7

    @limbeboy7

    Ай бұрын

    I've never heard anyone kill themselves bcuz they were smoking weed.....

  • @Ikibrii

    @Ikibrii

    Ай бұрын

    ​@@limbeboy7I agree. However, my ex smoked sooo much weed, and ended up with a schizophrenia diagnosis. Its not totally risk free, if you smoke at lot before 25. Your brain will stop develope.

  • @RyanWilliams222

    @RyanWilliams222

    Ай бұрын

    Agreed. Traditional antidepressants seem pretty crappy by comparison to these next-generation solutions. Personally, I’ve had good luck with Mindbloom for depression. (Which is at-home oral ketamine sessions. Ketamine is not a classic psychedelic, but some people consider it a quasi-psychedelic.)

  • @InsertNameHere2024

    @InsertNameHere2024

    Ай бұрын

    Agreed. Something like half of people coming off zoloft say the withdrawal symptoms were severe. Thats no joke. It was the worst 48 hours of my life. And I was tapering very slowly. They're good, but not really designed for long term use. But of course, they're also profitable, so support to come off them is terrible.

  • @bellasmom2597
    @bellasmom2597Ай бұрын

    I take mushrooms for depression. Took MDMA to see if I could stop reliving trauma

  • @spontaneousbootay

    @spontaneousbootay

    Ай бұрын

    Depression is a result of unresolved trauma. The next time that you trip, keep a notebook nearby. Then think about how you express yourself in everyday life and write down the insights. think about how honest you are with yourself and your lifestyle. Pay attention to the stories that you tell yourself

  • @bellasmom2597

    @bellasmom2597

    Ай бұрын

    I am indigenous Canadian things done by nuns in residential school to my bio mother she then did to me. I would rather not remember all my trauma.

  • @spontaneousbootay

    @spontaneousbootay

    Ай бұрын

    @@bellasmom2597 they must be processed as an adult. You remember them as a child and the emotional wounds are left open. Such as recognizing that your mother was also reliving her hurt in an effort to feel safe. Ideally, you may want to do this with a therapist.

  • @hamidtrk58
    @hamidtrk58Ай бұрын

    Is your book available in Swedish?

  • @DrKaran

    @DrKaran

    Ай бұрын

    I’m not sure actually! Do you mean a Swedish translation?

  • @juliedavies1513
    @juliedavies1513Ай бұрын

    After years of the unsuccessful policing of football hooliganism in the1980s, it has been shown that ecstasy was far more effective at stopping the violence as the people engaged in it embraced rave culture instead of fighting.

  • @Olliejz
    @OlliejzАй бұрын

    Millions of anecdotal testimonials about how these cured extreme depression, anxiety and other mental illnesses alongside the many dozens of conclusive studies about this topic make it irrefutably an efficacious treatment, while being significantly safer than other legal psychoactive products like alcohol or cigarettes.

  • @MrMokey24

    @MrMokey24

    Ай бұрын

    Show me one conclusive study on efficacy of psychedelic treatment for depression. These studies are preliminary at best.

  • @Olliejz

    @Olliejz

    Ай бұрын

    @@MrMokey24 The evidence is overwhelming, regardless of the depth of the studies. I speak from personal experience too. I believe the studies will show further than preliminary proof when the government and regulatory bodies allow them to be studied fully. Interested to know what you think.

  • @MrMokey24

    @MrMokey24

    Ай бұрын

    @@Olliejz Hm, my thoughts. These compounds have been available for human consumption for a longer time than even written history. If they were easily used to cure mental illness, there would have been more widespread use. I agree, more research is needed and I fully support a legalization of all psych drugs (LSD, shrooms, dmt and others). But I don't want people to hurt themselves with drugs nobody yet fully understands.

  • @Olliejz

    @Olliejz

    Ай бұрын

    @@MrMokey24 I see your point definitely, however I think the current zeitgeist would benefit significantly more than in any other time in history. People have been using these things for generations safely. I also agree that it becoming legal wouldn't be all sunshine and rainbows, because some poor kids would end up taking too much too early and hurting themselves.

  • @capitalisa

    @capitalisa

    Ай бұрын

    @MrMokey24, with all due respect, if your concern is that people not be hurt by drugs, then you would support the banning of NSAIDS. They kill thousands every year, destroying livers and kidneys. Every drug advertised on television has a list of devastating side effects and death. The line you apparently draw concerning safety is arbitrary and not based on facts.

  • @tainicon4639
    @tainicon4639Ай бұрын

    (If you commented on this in the video I will correct it haha) I find your use of fly agerica mushrooms in the thumb nail interesting… technically hallucinogenic but I don’t think it’s truely psychedelic. The main compound in those mushrooms is muscimol a deliriant hallucinigen. It causes hallucinations by modulating gaba receptors. Unlike classical psychedelics which seem to increase glutamatergic drive through 5-HT2a receptor modulation (it’s metabotropic receptor modulation so the actual ionatropic changes are down stream).

  • @MephitisUK
    @MephitisUKАй бұрын

    Regularly microdose with psylocibin and it's done wonders for my anxiety and depression. I've also heard good things about DMT but have yet to try it.

  • @robertwilks-yk6hi

    @robertwilks-yk6hi

    Ай бұрын

    I went and tried dmt first before mushrooms. Dmt is amazing, it's definitely not for the faint hearted but definitely should be tried.

  • @stiffk666

    @stiffk666

    Ай бұрын

    I miss not having access to shrooms. They're so hard to find I wanted to grow my own but nowhere will post to the UK. I certainly used to feel so much better after them with zero side effects. It's just wrong they can make something so natural and happy illegal.

  • @MephitisUK

    @MephitisUK

    Ай бұрын

    @@stiffk666 There are spore sellers in the UK. Plenty of youtube videos to show you what to do and what not to do.

  • @stiffk666

    @stiffk666

    Ай бұрын

    @@MephitisUK I'd be too worried it's a scam, or maybe a trap or something. I have to pick the mowers mushrooms out my lawn before my daft puppy eats them and every time it's a wistful... If only... It's funny how he was saying about docility of people. I remember seeing the Chemical Brothers in Brixton and the whole place was obv on mdma and we had the best night ever, everyone dancing and happy and hugging each other. No trouble at all.

  • @jackbarnes5589
    @jackbarnes5589Ай бұрын

    Many might disagree with this, but what changed my life for the better was actually medical marijuana. Helps with mental problems like my anxiety, Autism, and ADHD. It has also worked wonders for my migraines. We were told so many lies about things like Cannabis and Psilocybin.

  • @Tegdirb64

    @Tegdirb64

    Ай бұрын

    I'm taking medical cannabis too and finding fabulous for depression, anxiety and chronic pain. It is perfectly possible to get access here in the UK and the cost can be mitigated through the Curaleaf Access Scheme

  • @zed4694

    @zed4694

    Ай бұрын

    Yesss same. Works well with my autism and bipolar/bpd Can’t be on shrooms cause I’d get myself killed 😭 my rule is to not try things that can lead to an overdose or make you do things you wouldn’t wanna do.

  • @josephdemaree8401
    @josephdemaree840128 күн бұрын

    Muslim here, everyone knows we think intoxicants are haram. But even we have rules that say when they are for the benefit of the sick to be used. What’s the difference between oxidation and morphine vs medical prescribed marijuana and magic mushrooms. 12:15

  • @anonymoushawk962
    @anonymoushawk96217 күн бұрын

    I don’t know if using this stuff for OCD is a good idea… low doses of psychedelics can feel like you’re “wired” in a slightly trippy way… you can get thought/experiential loops… I’ve found myself having a form of OCD on this stuff at high doses. Idk that’s just my experience.

  • @bsm8444
    @bsm8444Ай бұрын

    did u change the name of the video?

  • @DrKaran

    @DrKaran

    Ай бұрын

    Yes

  • @bsm8444

    @bsm8444

    Ай бұрын

    @@DrKaran Ok so i guess i wasn't tripping 🤣 Great video btw, gives a new perspective to Psychedelics. Being from a Sikh background I found the part about bhang very interesting. Maybe I should give it a go haha

  • @robertwilks-yk6hi
    @robertwilks-yk6hiАй бұрын

    Dmt changed my life. I see it as medicine, only take it now and then.

  • @skyeblu4391
    @skyeblu4391Ай бұрын

    Yes, me an my daughter have. I had sever depression in my 20s did mushrooms never depressed again. 2 of my daughters wanted to die did mushrooms never felt that again. It s true morw then you ill ever know. None of us ever had that dread again. EVER

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    I would not take your word for it because I doubt the mushrooms were the ONLY thing involved in helping. If you had therapy ahead of taking mushrooms, that likely helped. And your daughters wanting to die? I'd question how you were treating them first of all.

  • @fourtyseven47572

    @fourtyseven47572

    Ай бұрын

    ​​@@Jake38nine Obviously its not the only thing that helped but to say it played no part is dumb

  • @janineclemons746
    @janineclemons746Ай бұрын

    My understanding is that psilocybin and LSD increase neuroplasticity. The problem is that those who come from a traumatic childhood often end up in similar relationships as adults. Being immersed into a toxic environment after this intervention seems counter productive.

  • @warbler1984

    @warbler1984

    Ай бұрын

    Thats a very broad term...neuroplasticity can be positive or negative as he stated "the direction of relationship makes people more connected"

  • @keylasharp8281
    @keylasharp8281Ай бұрын

    I've always been to terrified to do mushrooms because I've always been told you can lose your mind and not come back

  • @spontaneousbootay

    @spontaneousbootay

    Ай бұрын

    That's just fear mongering. The only thing that you should know is that nothing good comes without pain. Sometimes you feel sick for a bit

  • @DrKaran

    @DrKaran

    Ай бұрын

    I’m not endorsing recreation use but in clinclal settings it is proven to be safe and has a lower side effect profile than many current medications

  • @spontaneousbootay

    @spontaneousbootay

    Ай бұрын

    For some young people, they claim to have developed dissociation disorders. A well known one is Andrew Callaghan of channel 5 yt channel

  • @MrMokey24

    @MrMokey24

    Ай бұрын

    I wouldn't take them, don't trust these doctors, the use of mushrooms in a clinical setting is only recommended after conventional treatment fails. That's for a reason, we don't know the full range of side effects just yet.

  • @Eliqueme

    @Eliqueme

    Ай бұрын

    This is true, But as you said "in clinical situations/ trials" ​@DrKaran I've heard and seen people be dumb and act like it is recreational in nature when it's something my people see as spiritual and cultural, And they come out with a sort of HPPD for days to months even due to over consumption for any number of reason. In a controlled manner and environment it is absolutely beneficial, We just need good regulation/common sense law

  • @Lisa-si1wp
    @Lisa-si1wpАй бұрын

  • @MesieurOjete
    @MesieurOjeteАй бұрын

    I've been treated with Sertraline and for me the side effects were worse than of weed for more or less the same effects.

  • @MesieurOjete

    @MesieurOjete

    15 күн бұрын

    @morseemily sorry dude, weed is all I need

  • @lotterwinner6474
    @lotterwinner6474Ай бұрын

    I'm having a hard time getting through this video. I'm getting so angry thinking of the politics of controlling peoples health. Land of the free my ass.

  • @francescoserio781
    @francescoserio781Ай бұрын

    This content is nut(t)!

  • @DrKaran

    @DrKaran

    Ай бұрын

    Lol

  • @Roctwn16
    @Roctwn16Ай бұрын

    All in for 🍄

  • @SiggyPony
    @SiggyPonyАй бұрын

    naw too short :( But great video

  • @DrKaran

    @DrKaran

    Ай бұрын

    Almost an hour haha! Good stamina if you watched it all

  • @Digitalhunny
    @DigitalhunnyАй бұрын

    I've said it for decades, _"Every_ single leader on this planet, whether they be in government, religion or mass industry, should be mandated to partake in no less than 5 guided mushroom trips before taking office!" You wanna see world peace happen? This is how we _start_ to achieve world peace & end pollution & world hunger. This is _only_ the very tip, of the very most top, of the beginning though. We sincerely _could_ shoukd be so much better together. Shrooms simply allow us to find connection to ourselves, most others & nature. It honestly is that easy, & for that alone it's scary. ❤

  • @antlerman7644

    @antlerman7644

    Ай бұрын

    Nutty

  • @kurtpleavin

    @kurtpleavin

    Ай бұрын

    ​​@@antlerman7644 spoken like a person/bot that has never had a mushy trip. I'd recommend having 3g in a nice space perhaps in nature or with a nice playlist on and just enjoy the interwoven nature of the world as a start but please consider your own tolerances beforehand. Edit - spelling.

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    Debateable. You have no idea how it will affect other people. And if their hallucinogens, then you cannot predict what another person may see. What you see as peace another person could see as savagery. Connecting to nature also means all the suffering and savagery that comes with it. There's no peace in nature. Only survival. Even pants don't survive. However, plants are not conscious enough to be aware of their surroundings, thus they do not have survival instincts. Everything in nature is made to serve another being. There's a natural cycle of life. Everything in nature is sustenance to another. Even the predators eventually become sustenance to scavengers, bugs, and the soil that plants grow from. If you want to truly connect to nature, go live in a forrest for the rest of your life with nothing but the skin on your hide. That's true connection to nature. You will NEVER be truly connected to nature for as long as you have the current technology you are using to make these statements or even the clothes you're currently wearing. No amount of drugs will ever connect you to nature. And I can guarantee that if you took these shrooms in nature, nature would not care about your peace or safety because while you're hallucinating that a puma is your regular house cat, the puma has already ripped out your throat. Nature will not care about you because nature is not peaceful.

  • @Jblah

    @Jblah

    Ай бұрын

    Thats the dumbest thing ever. Youre also proof of the problem which is ill education. We need indepedant qualified experts to lead us, not paid trolls. Thats the problem

  • @Jake38nine
    @Jake38nineАй бұрын

    They may be less dangerous, but do we really want people getting addicted to hallucinations for a better good feeling in their tummies rather than having them work through their problems in a healthier manner that allows them to be self-aware and accountable? Plus, I don't want anyone hallucinating while they're driving.

  • @onfire8179

    @onfire8179

    Ай бұрын

    Protip: Watch the video before you comment.

  • @fourtyseven47572

    @fourtyseven47572

    Ай бұрын

    A lot of pyschedelics have a very very low potential for addiction as the tolerance is extremely strong and sets in about 4 hours after first usage. If I wanted to take LSD everyday for 2 weeks and feel the same high each time, id need about 8000 tabs. If I wanted to get drunk everyday for 2 weeks id need like 2 or 3 bottles of hard liquor.

  • @ab-js2gw

    @ab-js2gw

    Ай бұрын

    No we want people to get addicted to alcohol and pretend that 14 units per week is absolutely no harm, on top of that let's normalise ultra processed food and being any weight is healthy.

  • @successblueprintinstitute
    @successblueprintinstituteАй бұрын

    Dr Karan is such a G

  • @DrKaran

    @DrKaran

    Ай бұрын

    :p

  • @kylenmaple4668
    @kylenmaple4668Ай бұрын

    Most of the greatest thinkers in history ingested psychedelics. Might be a sign

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    That's impossible to say. That's a bias you came up with based upon biased information you heard. I highly doubt you actually looked into every great thinker in the entire world's history. "greatest thinker" is also a neutral phrase. You are likely thinking of it as a positive phrase, meaning you think of certain thinkers as the greatest because they did or said good things. However, even the greatest of thinkers can be horrible people. It's also hard to depict who is a great thinker as those two words are opinions and biased. Hitler was a thinker and could even be considered a great thinker. There is no general rule or proof of "Great thinkers" because there is no such thing as a great thinker. Only our interpretations, which are opinions. Just like the hippies who said they connected with nature, yet wouldn't actually leave their cozy societal communities within the safety of human protection. If hippies truly cared about nature, they would've gone and lived within nature. None of the hippies actually went and lived in nature. Because if they did, we wouldn't have so much history about them obstructing other humans. Why couldn't hippies leave society and human regulation and create their own place in nature and defend themselves in nature? Why do we even know the names of famous/infamous hippies? It doesn't logically make sense. If Nature could actually speak for itself, Nature would even reject hippies because hippies were too cowardly to actually leave human society and fend for themselves. Literally nobody is stopping you from leaving human society and living in nature and fending for yourself. This is why I beleive hippies were the beginning of virtue signaling cults. They wanted to pander to things that they didn't even take seriously. Once again, if hippies took nature seriously, they would've made a statement by leaving human society, not leeching off of human society.

  • @kylenmaple4668

    @kylenmaple4668

    Ай бұрын

    @@Jake38nine you need to calm down. People on the internet are not your enemy, you gotta direct this energy into something more constructive. This entire rant you typed up is a manifestation of exactly what you described hating: virtue signaling BS coming from an angry lazy entitled ignorant child on the internet You can extrapolate whatever the hell you want from my comment. Psychedelics have been a part of nearly all recorded cultures through time. This is a well accepted fact. The stigma around drugs is a very modern thing, and there is quite likely something to gain from these substances. Humans can uniquely benefit from drastic shifts in perspective. This has been well understood by humans for thousands of years, hence the entire idea of “right of passage” or “hero’s journey” or whatever. Mind altering chemicals provide a shift in perspective, and have been utilized as such for thousands of years. They do serve a purpose, whether you like it or not.

  • @Jake38nine

    @Jake38nine

    Ай бұрын

    ​@@kylenmaple4668 Mmmmmm nah. You just ignored and denied my entire argument, so I'll do the same to you. Lol. Treat others how you want to be treated. You're too far gone on your drugs. Maybe get off them and start thinking for yourself instead of needing a substance for all your ideas. Also, the video was about shrooms curing depression and anxiety, not perceiving a different world. Guess what? I've been 100% sober my entire life minus 1 night. I have a creative mind and can see millions of different perspectives without a damn drug. You need get better at thinking. Needing a drug to make you better at thinking is kinda pathetic.

  • @felixking1072
    @felixking1072Ай бұрын

    Its legal here in Canada. I really dont see what the big deal is. Its unbelievably strong, even in really small doses. Its hard to function and do everyday things. I dont really see what the hype is about. I just high nothing therapeutic about it. Ill just stick to weed.

  • @ChuckNorris-lf6vo
    @ChuckNorris-lf6voАй бұрын

    Hi doc my theory is that the psychedelic O.C. the brain temporarily and all the tree of thought is calculated at once, which results in a "game reset" for the human. Also works well with proper pre-feeding the system for the O.C. event. Not a biologist.

  • @7kortos7

    @7kortos7

    Ай бұрын

    I like that you wrote this immediately without watching the video. lmao

  • @ChuckNorris-lf6vo

    @ChuckNorris-lf6vo

    Ай бұрын

    @@7kortos7 your comment is irrelevant.

  • @Jay-ho9io

    @Jay-ho9io

    Ай бұрын

    ​@@ChuckNorris-lf6vo completely relevant. Spamming a video you haven't even watched with your comments before the videos even completed actually attacks your argument, so we're better off not even hearing it.

  • @shivanipandey7544
    @shivanipandey7544Ай бұрын

    plz hindi sir.......ap bo bala system krdijiye jismin.ap english boly pr hindi translate dikhy ..plz ...plz plz plz plz plz plz plz plz plz

  • @maks69420
    @maks69420Ай бұрын

    Fhru

  • @oligennbashconnects
    @oligennbashconnectsАй бұрын

    The main worrying thing about psychedelics is the US army providing psychedelic treatment for the people who's lives they've ruined. The traumatised soldiers don't have a disorder...they're the only ones with a shred of humanity left

  • @sct27271
    @sct27271Ай бұрын

    Magic mushrooms practically gave me PTSD and I’m certain it kicked off my many years long struggle with clinical depression

  • @untipo.
    @untipo.Ай бұрын

    I won't never understand why scientific communicators from usa act like they are speaking to kids 😂

  • @DrKaran

    @DrKaran

    Ай бұрын

    Neither one of us are from the USA

  • @wmdkitty

    @wmdkitty

    Ай бұрын

    Well... here in America, we have a significant population that refuses to get educated past the fifth grade. The science communicators are, in effect, speaking to children.

  • @jonathanhunt5687
    @jonathanhunt568729 күн бұрын

    You lost me at the Salem witch trials and talking about ”misogyny” as if there weren’t occult practitioners that deserved such a fate now I’m not saying everyone was a witch but saying that is was all nonsense is very naive and you’ve lost a viewer for allowing such a secular and evil viewpoint be established

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