Your channel is legit af, dude.👍 Very informative and professional content. I hope your channel continues to grow and becomes monetizable. Keep it up.

@isaacwadepharmd3969

2 жыл бұрын

Thank you much appreciated!

I just noticed that my audio and video are a bit out of synch. Apologies for that. Hope it doesn’t take away too much from the content.

@intuitiveclass6401

Жыл бұрын

Thought it was just the weed I smoked

0.025% per 1ml has been shown to be the best when it comes to hair loss prevention and reducing sides. Scalp dht reduction was -55% and serum dht reduction was -24%

@abbasq4263

11 ай бұрын

So how many sprays would you need of topical finasteride for 0.1 and how many times a day?

@endritgooglekonto230

9 ай бұрын

​@@abbasq42631x daily

@bumpak

9 ай бұрын

4.5 sprays@@abbasq4263

@luisl2950

5 ай бұрын

​@@abbasq4263 1-4 once a day

Thx Issac for making these videos you help out many men out there and your videos are high quality

You deserve much more subscribers my man. Keep going and soon you will have your first 10k ✌️

Saying that oral finasteride is safe is misleading because it really is just a gamble, either you're lucky enough to not get serious problems like erectile dysfunction, fatty liver, depression or etc. or you're unlucky and you get some if not all of them. In any case finasteride can be a blessing but it just so happens that the line after which it becomes a curse is pretty small. ANY systemic exposure to finasteride for a MAN who loves being a man and wants to remain being a man is unnecessary. Quote from Rob English review on the topic - "stick to 1-2 mL of 0.005% to 0.02% topical finasteride solutions. This equates to roughly 0.1-0.2mg of daily finasteride exposure to the scalp. Any more than that, and there’s risk of significant systemic leakage, which defeats the purpose of using topical finasteride altogether."

Great content as always. Thanks doc!

@isaacwadepharmd3969

2 жыл бұрын

Thank you!

Topical finasteride literally turned my hair around in 30 days. I literally sprouted a bunch of hair on my temples by day 4. Call me a liar,,,call me a crazy person…..I really don’t care. For me, the stuff worked IMMEDIATELY. Am I hyper responding? Maybe? But all I know is this stuff did the job for me. 2 months in and I am amazed. i use 0.3% topical finasteride 6% topical minoxidil….I spray one shot on each temple,,,one mid scalp, one spray on the crown……0 side effects.

@user-km9ed6zx1z

2 жыл бұрын

Wow , what about now?

@hiamp1000

Жыл бұрын

is this the forhims formulation? had you already tried 5% standard minoxidil prior to using this?

@NotUrDaddiesXLT

Жыл бұрын

By the math with this regimen you are getting 12mg per application. 24mg a day if you are doing it twice a day..

@NotUrDaddiesXLT

Жыл бұрын

By the math with this regimen you are getting 12mg per application. 24mg a day if you are doing it twice a day..

@nunya6023

6 ай бұрын

Your post is misleading. You used minoxidil and that is why you saw quick results.

I've been doing my own scientific study on myself, and I can tell you that 0.002% topical finasteride works perfectly, it just takes longer to get results, but that's obvious it would be the same with any drug. Don't bother with 1mg oral, it's a ridiculous amount.

@justinjacobson1414

2 жыл бұрын

How do you get that low of a percentage?

@adampalmer162

2 жыл бұрын

It won't work for prevention

@52yamahar1

2 жыл бұрын

@@adampalmer162 what dosage would you suggest that would?

@adampalmer162

2 жыл бұрын

@@52yamahar1 I personally use 0.25 pill for preventative measures and then the rest in a solution form. I have been told by a dermatologist this is a good idea to minimise/prevent side effects and get good results. For regrowth he said you need 1mg. The issue with only using a solution is that it does not go fully systematic so would only be effective in the areas you apply it but you could always give it a go.

@justinjacobson1414

2 жыл бұрын

@@adampalmer162 .25 should still increase thickness of existing hair. Also there’s some growth agonists you could try besides minoxidil. Micro needling alone tends to be as effective as minoxidil alone.

Topical Finasteride is great indeed hair growth is awesome. I’ve used it for the past 3 years. Using 1ml per day. No significant sexual side effects but after all this time I developed NASH (Liver Disease) and when tested AST and ALT were over the top. My diet was not that worse, it felt very strange that I had such high levels of AST and ALT. I one day stumbled on a recent research that inferred suppression of DHT has been linked to NAFLD and NASH. I thought that maybe Finasteride is causing so I’ve stopped using it from past couple of months and after I got myself tested again, there has been a significant reduction in my AST and ALT levels. You should check that research out. Author is Abdul Maged Traish. Your response would be highly appreciated.

@SACKBOY123432

2 жыл бұрын

The Mazzarela et al study was using 0.005mg fin. The point of topical is to prevent it from going systemic and affect your liver and nervous system etc. If I were you I would try it with a lower dosage then compare if you still get sides

@unassailable6138

2 жыл бұрын

Mix a quarter tablet of finasteride into a 100 ml bottle of minoxidil and spray 3 times a day thats 0.005% and it will NOT penetrate your blood serum. watch this video kzread.info/dash/bejne/gKmMldh-oZWzkdI.html If your poop is coming out brown and not yellow or whie , your life is still good, fina destroys choleangyocytes which make bile.

@ETin6666

Жыл бұрын

That's interesting. I've also been using topical finasteride (0.1%, 0.5ml per day) since 2018 and recently underwent a bunch of tests for a surgery. All seems perfectly fine. Maybe it's the small dosage or maybe age plays a part, I was 29 last year when I got the tests. What's your age if you don't mind me asking?

@infinitium3863

Жыл бұрын

@@SACKBOY123432 I have started again now with only 0.35 ml once a day and only at places of thinning since the quantity is low, its been a couple of weeks and I’ve been losing hair like crazy. Which i guess happens after starting minox and finax topical.

@natanaelpinturas

Жыл бұрын

What % percentage of finasteria did you handle?

In 2011, reports of finasteride-related depression and suicidality led to an FDA post-marketing reportopens in a new tab or window. Depression was added to the adverse reactions section of the drug's labelopens in a new tab or window, which already listed several sexual dysfunction-related adverse events, including erectile dysfunction and libido, ejaculation, and orgasm disorders. Now new research has linked finasteride with a significant reporting odds ratio (ROR) for suicidality, depression, and anxiety, particularly in those younger than 45 and those with alopecia, as opposed to older men with BPH. Quoc-Dien Trinh, MD, of Brigham and Women's Hospital in Boston, and colleagues found that among 3,282 treated patients, there were 2,926 reports of psychological adverse events -- defined as cases of depression and anxiety -- associated with use of finasteride. As the team noted in the study online in JAMA Dermatologyopens in a new tab or window, this equated to a more than four times higher risk of experiencing depression and anxiety while using finasteride (ROR 4.33, 95% CI 4.17-4.49).

How scalp dht will reduced with topical finastride if dht is itself transformed into prostate from testosterone by 5 alpha reducatase, finastride ia not dhr blocker its a 5 alpha reductase blocker which is present in prostate so finastride need to travel way to the prostate which is leas likely to happens in case of topical as quantity absorb would be significantly low

what was the concentration of the solution used in the study, i think you said 0.025 which has shown to reduce scalp by 50 percent and serum dht by 24 percent in other studies

Using it for years, i do the 22,5mg per 90ml Solution concentration so 0.025mg per 1ml, no sides, hairline got back and crown fully thick.

@moha2479

2 жыл бұрын

No any sides? Really? And the erectile doesn’t change at all?

@justinjacobson1414

2 жыл бұрын

@@moha2479 some people report higher libido

@shajjj455

2 жыл бұрын

@@justinjacobson1414 higher

@shajjj455

2 жыл бұрын

@@justinjacobson1414 ??

@JJ1802

Жыл бұрын

@@moha2479 no

Nice to see a new video!

Dr. The side effects for sure is different I’m on topical and no side effects My hair looks the same when I had the oral. The difference in between topical dutasteride and finasteride need to see. I will let you know soon I’m changing dutasteride to see if better results than finasteride

@guspit1503

Жыл бұрын

Hello! So, have you seen any significant difference with topical Dutasteride?

@PippyPappyPatterson

Жыл бұрын

Bump for update on topical dut

@stephengoodell5984

Жыл бұрын

Any updates on the topical dutasteride?

@johntailor2000

3 ай бұрын

hi, any update my friend ?

I started using 0.005% (0.05mg) topical finasteride last week. So far I seem to be tolerating it ok. Was on 0.025% before but experienced SE, so I stopped. Will update in some time.

@hamidaabdenour9092

Жыл бұрын

I can't grab it this idea of side effects maybe you are borderline hypogonadal so that stoping some DHT pushed u to get SE because I'm taking FEN orally and topically and I'm pretty good on all levels

@alexanderhari3000

5 ай бұрын

@@hamidaabdenour9092 i think it's that i have high t and high e relatively, so that small levels of dht converting to e makes me experience SEs. Ive been weaning myself on topical very slowly and have worked up to 0.1mg/mL daily with minimal side effects

@alexanderhari3000

5 ай бұрын

@praywithoutceasing4939 topical from minoxidilmax, but i use their PG free solvent to dilute it

What is your protocol for hair loss? Granted, it looks like you don't have an issue

@isaacwadepharmd3969

2 жыл бұрын

Thanks! I use oral finasteride 1 mg and minoxidil 5% 1 ml once a day

It's like I woke up one morning and realized I'm going bald. It was bad, I guess I just never look at the back of my head. I've been using topical finasteride with minoxidil in combination with biotin and dht reducing shampoo. I can't believe how good it has worked in only 2 months. I don't look like I'm going bald any more. I am coupling this now with .5mm depth gun microneedling and prp injections. Even though if the results I have now are the best as it will get I'd be happy. As of now I'm just trying to keep my gains.

@CNYPED

2 жыл бұрын

Congrats. Where do you get your topical? I’m in usa

@infinitium3863

2 жыл бұрын

@@CNYPED you can consult the compounder to get your formulation.

@Ogachagga

Жыл бұрын

Even if you go bald completely its not the end of the world

@realtalk37851

Жыл бұрын

@@infinitium3863 do they do that in America 😢

@DOCFIT_09

Жыл бұрын

​@@CNYPED here its available for 10-15$ depending on the concentration of finasteride nd minoxidil...do let me know if you want to stock some

Absolutely horrendous detrimental neurological side effects frpm topical finasteride and the nukbers dont lie and are rapidly increasing with injured men from topical finasteride.

I have been using XYON 2.5% topical finasteride with 3% minoxidil gel daily for the past 1.5 months. After the first 2 weeks I noticed some sides such as loss of sex interest and more importantly loss of morning erection (which I used to have daily before starting the topical gel). To exclude the psychological effect, I kept using the gel daily hoping things would change if it was only in my head. Unfortunately, It’s still the same sides. My concern is that this 2.5 % is super high dose (=25 mg finasteride on scalp). So even if very little absorbed, say 5% of the 25 mg, it means 1.25 mg goes systemic which is like an oral dose). Any insight or feedback ?!

Many thanks for video.. which is safer topical frenstride or topical dutestride?

@p51mustang24

Жыл бұрын

Dutasteride is stronger and more likely to produce side effects, although it also has better results. It just blocks DHT much more aggressively than fin.

My dermatologist prescribed 5% Minoxidil and 0.1% finastride 1 ml twice daily... Is that safe?

lookin buff man, great video. what do you use for your hair doc ?

@isaacwadepharmd3969

2 жыл бұрын

Thanks! I've been hitting the weights recently. I use oral finasteride 1 mg daily and minoxidil 5% once daily. ketoconazole 2% once in a blue moon as well

@ameerskater

2 жыл бұрын

@@isaacwadepharmd3969 oh wow! Your hair literally looks perfect I would have never guessed you were on minoxidil too

Hey doctor. For topical finasteride can I just apply 1mL on my frontal head and temples ? (Not crown or anything) and that would be good enough ?

If I had that head of hair I would sleep like a baby at night and no comments would bother me, lol

0:23 I would not call these reports rare. You see a ton of them every time you look up anything about finasteride

Great hope, thanks

Couldn’t it build up over time to decrease the same amount dht as oral?

Ugh I’m so depressed. I used topical dutasteride and oral fin and topical minoxidil and results are just as poor

@chandlersmithers5876

2 жыл бұрын

Exactly, I think people try to associate their depression from finasteride not working for them to being a side effect of it, when in actuality it is probably simply depression from the drug not working

Bro u making me feel bad for the last comment I left

@jackd2990

2 жыл бұрын

It was a just a joke homie don’t take it seriously

there’s no way only 1% of men get sides gotta be closer to 25% - 50%

@BudaMac

Жыл бұрын

Agreed…most finasteride videos are littered with people in the comments explaining side effects

@midnight816

10 ай бұрын

You can’t estimate this number based off comments on the internet. Ppl without sides won’t be as loud about it as the ppl with sides.

@tpipandpop4242

5 ай бұрын

Agreed. I know 3 people who took finasteride and all 3 have since quit due to side effects.

@SHOUTxHIxHEYxHELLO

5 ай бұрын

​@@tpipandpop4242 yep same, out of the few friends and myself that have tried it all of us quit, and all said it killed their libido, would rather having a functioning dick than hair honestly

I'm 18 years old suffering from body dismorphic disorder and i started noticeing weird stuff happening to my hair, i'm super anxious i'm going to lose it and idk what to do, please help me :(

@SACKBOY123432

2 жыл бұрын

You should first and foremost consult a dermatologist to find out whether or not you have androgenic alopecia(male pattern baldness) get your bloodwork done to find out whether or not you lack any vitamines such as B12, D3 or Omega3. If it's MPB they are probably going to tell you that you are a bit too young for Finasteride or a hair transplant, and you should instead use Minoxidil 50mg/ml once in the morning and once in the evening. You can also buy a dermaroller which makes minoxidil absorb better into the scalp, just be careful not to dermaroll right before applying minoxidil as you will absorb too much. Instead if you have a 1.0mm/1.5mm dermaroll do it once per week/fortnightly and 1 hour or so before minoxidil. Also if you have a cat don't let them near minoxidil, even residue on a pillow case can be deadly to them.

The solution Hims sells is .3% finasteride mixed with min. Is this concentration higher than necessary? Would I want I dilute it even more?

@chrisadams7984

2 жыл бұрын

Way too strong - you only need about 1/10 of that. Remember, other than saving/regrowing hair, the whole point of using topical finasteride is to reduce side effects (otherwise, you may as well just take the pill). According to the study cited, the optimal concentration to achieve both hair regrowth and reduced side effects is about 0.025%. There were stronger concentrations that were a 'little' more effective at reducing scalp DHT, but they resulted in much higher systemic absorption (which would presumably result in a much greater chance of side effects).

@ugglanvu

2 жыл бұрын

@@chrisadams7984 when you write 0.025%, you mean 0.25 of finasteride blended in a 1 ml solution?

@chrisadams7984

2 жыл бұрын

@@ugglanvu Yes, if you use a 1ml application size, then 0.025% would = 0.25 mg. of finasteride per 1 ml (a 0.25% solution would = 2.5 mg finasteride per 1 ml ---> way too strong; I mention this so you don't confuse the two). The goal is is save/regrow your hair while MINIMIZING the side effects (otherwise, you may as well take the pill orally). The last Caserini Study suggests that this happens with a DAILY topical dose of 0.025% or 0.25 mg of finasteride. Assuming you are mixing/dissolving your finasteride with minoxidil (60 ml bottle) and applying 1 ml of solution to your scalp ONCE per day, you would dissolve 15 mg of finasteride into your minoxidil solution (60 ml/1ml) x 0.25 mg=15). If for example it takes 2 ml of solution to cover your scalp, then you would mix 7.5 mg of finasteride per 60 ml of minoxidil (60 ml/2 ml) x 0.25 mg = 7.5) . Here is a good place to start: kzread.info/dash/bejne/paihxbGIgLqZkaw.html

@ugglanvu

2 жыл бұрын

@@chrisadams7984 thank you for the thorough explanation, boss!

@Frenchieeeee

2 жыл бұрын

@@chrisadams7984 How would one dilute the Hims .3% finasterid/min spray? Do you just add water or does that mess with the active ingredient? Obviously i would need a different bottle.

I got typical side effects from oral and topical finasteride. But I am willing to try again with the topical, but maybe just less of it and less days a week.

@super-super-

Жыл бұрын

How often were you using topical finasteride? And how much of it were you using?

@Fury851

Жыл бұрын

@@super-super- I just mixed a tiny bit, a few drops into my bottle of minoxidrile. Very small amount. But next time I'll just use that maybe twice a week

@sonusuresh6642

Жыл бұрын

Hi you saw any results?

@Fury851

Жыл бұрын

@@sonusuresh6642 negative or positive results?

@sonusuresh6642

Жыл бұрын

Positive results. Did you see any positive results?

Hey Doc, how long after using 5% minoxidil does the regrowth stop? I'm seeing very limited results after approx. 8 month of using it (2 daily) and I don't know if there'll be more significant regrowth or if that's all I get from this medication.

@nemiw4429

2 жыл бұрын

Minoxidil > hair gets more blood, nutrition, doesnt die off. Not only growth, but the ones you have last longer.

@anthonypoon1305

Жыл бұрын

No, minoxidil peaks at 6-8 months of usage, you won’t get result better than this period, and the efficacy will wane, for me it is 1.5 yr

@kathleen2020

5 ай бұрын

Go to a dermatologist who specializes in hair loss. I’m so glad I did. There are several reasons for hair loss. Minoxidil or other treatments may not work for your hair loss. You will save time and money if you find the root cause of your hair loss.

I got weight gain in face and stomach area i think it's time to give a try for this topical one, hope it goes well

Is 0.25% 1 ml applied once a day with 5% minox too much to minimize serum DHT levels being affected?

@moealhaj3539

Жыл бұрын

Im trying to find this out too. Because I believe one of keeps or hims offer this

@NotAnNpc-l3i

Жыл бұрын

@@moealhaj3539 Mine is from keeps

@moealhaj3539

Жыл бұрын

@@NotAnNpc-l3i I figured. I honestly ordered from minoxidilmax the essegen 6+, it only glt .05% finasteride which means there is .5mg/ml, it is recommended to use 2ml daily so it will be 1mg of finasteride, but I will only be using 1ml a day for the first few weeks to test it out and if it works I will stick with it.

@moealhaj3539

Жыл бұрын

@@bazbuco I use .75ml 4-5 times a week. So far man, no sides at all, still horny 24/7 and no issues in bed. Too early to give you my feedback, but I hope it is worth it.

@NotAnNpc-l3i

Жыл бұрын

@@bazbuco I have not noticed any side effects nor improvement of my hairline at all.

Why is there no good topicals to buy out there wit ththe right doses

"Companies that profit off insecure men" and "given that hair loss is a purely cosmetic condition". You should rethink both statements. Not all men that use treatments for hair loss are insecure and hair loss is clearly not always a purely cosmetic condition. Great video, otherwise.

@AbstractAbsorption

Жыл бұрын

What would be a non-insecurity reason to seek treatment for hair loss?

@PrimePrius

Жыл бұрын

​@@AbstractAbsorption To be able to wake up and have messy hair. It's a nostalgic feeling

Nice video, thanks.

@wasteman3259

5 ай бұрын

Cheers mate

Does using transcutol p with topical finasteride leads to more systemic absorption

How much Finasteride Pills I have to put in a 60ml Solution for it to function?

@wolves1980

9 ай бұрын

You can buy it from hims or manual or sons

Your hair is great man. When you're 60 you'll be well equipped with the knowledge anyway lol

I recently switched from oral to topical finasteride. So far, so good....🤞🏻

@dustiin2274

2 жыл бұрын

Are there side effects of topical Propecia? I'm afraid to take some risks 💔 Is topical less dangerous than oral?

@traepalmer

2 жыл бұрын

@@dustiin2274 topical finasteride has the ability to become systemic (enter the bloodstream) but to a far less extent when compared to oral finasteride, so the incidence of side effects is lower when compared to oral finasteride but not completely zero.

@dustiin2274

2 жыл бұрын

@@traepalmer I'm afraid even of the low risk, if I don't get complete safety I'm afraid to take a risk, because I'm getting married in the near future, for you know the extent of the pain that I have to choice of losing my health with thick hair or I have a good health but with a head that looks like Bruce Willis

@traepalmer

2 жыл бұрын

@@dustiin2274 topical spironolactone might be worth looking into. Also, clascoterone may soon be approved for hairloss soon under the name "Breezula". To my knowledge, neither of those has systemic effects from topical use.

@dustiin2274

2 жыл бұрын

@@traepalmer I honestly have not heard of them, thank you very much for this information my friend ❤️ I will go to see the doctor and ask him about them, I hope we will get a hair cloning technique in the near future, it is the best solution

We’re not talking penis size here- so not liking balding isn’t an insecurity dude.

Where can I get topical finasteride ? Thank you doc

@ytsux9259

2 жыл бұрын

Special online pharmacies or make it yourself by mixing finasteride in with Minoxidil or another solution.

@ytsux9259

2 жыл бұрын

I mixed 60mg of finasteride into 60ml of Minoxidill.

@tgo007

2 жыл бұрын

forhims has it

@isaacwadepharmd3969

2 жыл бұрын

Great question! I believe it is sold by online pharmacies. I would compound myself if I could. Unfortunately, finasteride is regulated pretty strictly in Canada (due to the potential for birth defects) and my pharmacy doesn't have the facilities to compound it.

@BlazerMystic

2 жыл бұрын

@@isaacwadepharmd3969 thank you that you took the time to answer it and thanks for the great content Keep it up

What do you think about biotin or ashwaghanda

@Hosdam

Жыл бұрын

Biotin is a scam....aswaganda works

Great videos, you'll have many more subs soon

anyone here got any experience withr finsatetide minoxidil combo bottle from MANUAL in the uk

@js3k661

Жыл бұрын

I was in oral fin and minox from HIMs. Did it for 3 months and my sex drive went. I came off it and received the topical fin and minox combination from HIMs. But after I gained my sex drive back was to scared to try it. But now I’m back looking into it again

What about gel finasteride

If you are making your own topical finasteride, be careful with the dose used in the carrier. I have seen several posts from guys making there own version, but are using way too much crushed finasteride. So if you want to make 0.02% in a 60 mg bottle of minoxdil, the amount of fin' to make into powder would only be 1.2 (I would just use 1.5) milligrams of finasteride. Some people are using 15 mgs of fin' to place in the minoxidil. That would actually be 0.20% rather than the desired 0.02% dose. The mathematical equation is the amount to be used multiplied by the fin percentage. So one would multiply 60 (if using 1 ml drop full per dose) times 0.02, which comes out to the 1.2 mgs of finasteride. Just something to consider, and my advice is not intended to cure any medical issues, and is purely for entertainment purposes. Also, I am not a doctor.

@EvadeModsRGH

Жыл бұрын

This is wrong

@brandonl2175

Жыл бұрын

@@EvadeModsRGH okay if this is wrong can you or someone else please let us know what is right lmao

@YDfC21

11 ай бұрын

​@davidhead9083 this is how to correctly do it. 6mg in 60ml is 0.01%

I'm taking both lol

💌💌

Topical finasteride isn’t good the reason is say you are only applying 1 ml you won’t cover everywhere

@ytsux9259

2 жыл бұрын

Then apply as much as your scalp needs.

@boblully5053

2 жыл бұрын

@@ytsux9259 then more will go systemic 💀 you literally can only apply a few sprays but not cover the whole head

@ytsux9259

2 жыл бұрын

@@boblully5053 No need to cover the whole head, just the bald spots. 1-1.5ml can cover all of my frontal and vertex. And I don't spray; I spread it just like Minoxidil because I mixed finas into Minoxidil.

@boblully5053

2 жыл бұрын

@@ytsux9259 you are only covering the bald areas but what about when the rest of hair starts thinning . You have to use more ml which means that’s more 0.025 solution so more sides basically same as oral

@rubenn7212

2 жыл бұрын

@@boblully5053 Just make your own Disolve 0.25mg in 3 ml of minoxidil