The Lymphatic System Overview, Animation
(USMLE topics) The circulatory and immune functions of the lymphatic system.
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Voice by: Ashley Fleming
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In a nutshell, the lymphatic system is a drainage system that removes excess fluid from body tissues and returns it to the bloodstream. It is actually a subsystem of both the circulatory and immune system.
The major purpose of the circulatory system is to bring oxygen and nutrients to body tissues and remove wastes. This exchange happens in the smallest blood vessels called the capillaries. Blood plasma containing nutrients moves out of capillaries at the arterial end of capillary beds, while tissue fluid containing wastes reabsorbs back in at the venous end. However, not all of the fluid is drawn back to the bloodstream at this point. About 15% of it is left in the tissues and would cause swelling if accumulated. This is where the lymphatic system comes into play, it picks up the excess fluid and returns it to the circulatory system.
Unlike the blood circulatory system, which is a closed loop, the lymphatic system is a one-direction, open-ended network of vessels. Lymphatic vessels begin as lymphatic capillaries made of overlapping endothelial cells. The overlapping flaps function as a one-way valve. When fluid accumulates in the tissue, interstitial pressure increases pushing the flaps inward, opening the gaps between cells, allowing fluid to flow in. As pressure inside the capillary increases, the endothelial cells are pressed outward, closing the gaps, thus preventing backflow. Unlike blood capillaries, the gaps in lymphatic capillaries are so large that they allow bacteria, immune cells such as macrophages, and other large particles to enter. This makes the lymphatic system a useful way for large particles to reach the bloodstream. It is used, for example, for dietary fat absorption in the intestine.
Once inside lymphatic vessels, the recovered fluid is called lymph. Lymph flow is enabled by the same forces that facilitate blood flow in the veins. It goes from lymphatic capillaries to larger and larger lymphatic vessels and eventually drains into the bloodstream via the subclavian veins. On the way, it passes through a number of lymph nodes, which serve as filters, cleansing the fluid before it reaches the bloodstream.
Lymph nodes are small bean-shaped structures scattered throughout the lymphatic network. They are most prominent in the areas where the vessels converge. Lymph nodes contain macrophages and dendritic cells that directly “swallow up” any pathogens, such as bacteria or viruses, that may have been taken up from an infected tissue. They also contain lymphocytes: T-cells and B-cells, which are involved in adaptive immune response, a process that produces activated lymphocytes and antibodies specific to the invading pathogen. These are then carried by the lymph to the bloodstream to be distributed wherever they are needed.
The lymphatic system also includes lymphoid organs. Primary lymphoid organs - the thymus and bone marrow, are the sites of lymphocyte production, maturation and selection. Selection is the process in which lymphocytes learn to distinguish between self and non-self, so they can recognize and destroy pathogens without attacking the body’s own cells. Mature lymphocytes then leave the primary for the secondary lymphoid organs - the lymph nodes, spleen, and lymphoid nodules - where they encounter pathogens and become activated.
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I have been studying the lymphatic system since the beginning of the semester. I even went to a peer tutor, who sucked at explaining it and did not even know what he was saying. yet in just 4 minutes, you pulled everything together and made it make sense. Thank you so very much. You are saving lives!
@Zetsuke4
4 жыл бұрын
Gaby Chronicles yep my tutors sucked too
@blonblonjik9313
Жыл бұрын
Dont
@peacesoon
Жыл бұрын
Agree
@IDeclare
Жыл бұрын
Look up yahkiawakened
@christabeltruereviews
11 ай бұрын
@@IDeclare wat course does he teach
I'm a medical office administration student taking anatomy right now. Your videos are a huge help to watch before we start a new topic as an introduction and helps me not get so lost. :)
This is way clearing than a 45 minutes lesson in High school. Thank you.
@mikesmith7620
2 жыл бұрын
I think you forgot another line in your name
@princesshopetahura62
Жыл бұрын
yes
@subucreation9317
Жыл бұрын
@@princesshopetahura62 🦦
fast yet CLEAR explanation of the lymphatic system! Loved how you give explanation about the 'selection' bc I did not know what that meant lol! Thank you for your hard work put into this video. I have seen a couple of videos of yours - I will be following your page! Thank you again!
Finally! Watched so many explanations, but your video finally cleared for me how these systems work. Thank you!
@Rahulkumar-nu1hh
4 жыл бұрын
Right this video is really fantastic🤘😝🤘
@dgenjoy23
3 жыл бұрын
Same to you dear every confusion is clear 👍
@xhenialeksi6179
2 жыл бұрын
can you help mee please i have 2 years with this problem
Cant believe these 4 minutes were way more usefull than a damn 40min lecture of our professor
@joyo.9562
19 сағат бұрын
THAT PART!! 🎯
I LOVED how your video thoroughly explains the concepts. Thank you so much!!!
The best lymphatic system video I’ve come across,understood everything in just 4 minutes!
based on this video, this might be the best science channel. brief, concise, to the point, not a word wasted. every sentence is easy to understand conceptually. fantastic!
I always didnt understand the lymphatic system since high school until university, this 4 min video explains all, thank you so much
This is the best explanation on lymphatic circulation I’ve seen so far.
What a spectacular video. This channel is doing tremendous work. Many, many thank you’s!
your explanations are literally the best thing on youtube I've ever seen
Finally! right to the point video. Thank you!!!
thank you. i was searching this for years
I have taken up trampoline exercises for this reason in addition to the increased cardio workout without the jarring on the joints. Plus it’s fun to bounce - even a simple health bounce each day drains the system 🙌🏼
Thank god ive discovered this channel. You guys rock!!! So many incredible explanations
@BhavyaTiwari-fn8xz
7 ай бұрын
I am class 10th student here
This was THE best video for lymphatic system, my goodness that was amazing. Everything is clear to me now. Liked it!
Thank you so muchh i finally understand the lymphatic system and it feels amazing!
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This video clear all the dauts related to lymphatic system. Thanks a lot
Thank you for this video! Great explanation of how the lymphatic system functions!
Amazing video .I study from different video lectures but I cannot understand what is lymphatic system,how it's work.But after watching this animation not only my concept is clear but I remember it,and I can easily gain marks in exams ...
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Love you guys who teach like this with animations
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Tnx for your efforts 🙏 in explaining a clean and beautiful
OMG ...Finally found the best of it all..Thanks very much
Best video in this topic till date😍. Thank you
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Thank you! Good visual explanation of a marvelously designed system
Very concise and helpful Thank you so much
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well summarized and nicely delivered
Class notes confused me , this Helped so much thank you !
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Im doing level three anatomy and physiology for beauty therapy and this really helped me!
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Thank you so much now my all doubts are clear.
Thank you. This is helpful!!
Amazing video...crystal clear! I will soon join your site after my Lymphatic Drainage Course to support your videos...
Very clear explanation. Thanks.
Thank you for the valuable information provided.
Wow, very well-explained!
Best explaination ever brief but very precise. Thanks for making it easier for us.
@Alilamedicalmedia
Жыл бұрын
Glad it was helpful!
Easy to understand and very helpful, thank you:)
Thank you! This was very informative.
Struggling college student here, very good video. Thank you.
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Muchas gracias! Excellent video!
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@Alilamedicalmedia
Жыл бұрын
I'm so glad!
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that helped me understand so much!!!
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