The Evidence Based Hair Podcast was created by dermatologist & hair loss specialist Dr Jeff Donovan to highlight new, hot off the press, world-class research in the field of hair loss. The podcast was created for hair loss practitioners around the world who care for patients with all different types of hair loss. Each week, different hair loss research topics are covered in the podcast including new research related to androgenetic alopecia, alopecia areatea, telogen effluvium, traction alopecia, tinea capitis, trichotillomania, chemotherapy induced hair loss, lichen planopilaris, frontal fibrosing alopecia, dissecting cellulitis, folliculitis decalvans, discoid lupus, central centrifugal cicatricial alopecia, erosive pustular dermatosis.... and a whole lot more.
In this June series of the podcast, we focus on JAK inhibitors. This episode kicks off with a detailed review of an Italian study published in Expert Opinion in Drug Safety, which examines the incidence and management of infections in patients with alopecia areata treated with JAK inhibitors. Dr. Donovan discusses the findings, emphasizing that about one in three patients on JAK inhibitors may develop infections, highlighting the need for careful monitoring and potential treatment pauses.
Additionally, Dr. Donovan reviews a study from New York in Archives of Dermatologic Research, which reveals low vaccination rates among patients with immune-mediated diseases on biologics and JAK inhibitors. The study underscores the importance of pre-treatment vaccinations to mitigate infection risks.
STUDIES REFERENCE IN THIS WEEK'S EPISODE
Giacomo Caldarola et al. Infectious events in patients with alopecia areata treated with JAK inhibitors: low burden and minimal impact on persistence in treatment. Expert Opin Drug Saf. 2024 May 8:1-5.
Hren MG and Khattri S. Low rates of vaccination among atopic dermatitis, alopecia areata, psoriasis, and psoriatic arthritis patients on biologics. Arch Dermatol Res. 2024 May 25;316(6):285