This guy deserves all the funding he needs

@AAA-of4vk

2 жыл бұрын

indeed

@capri2673

2 жыл бұрын

It's a shame he gets botox and dyes his hair.

@theradicalaxe553

2 жыл бұрын

@@capri2673 Well he does eat mostly vegetables I don't blame him

@urossedonja3534

2 жыл бұрын

@@capri2673 ha good one. i noticed that too

@BurningDesire_letsgo

2 жыл бұрын

You all think that’s gonna happen as it will decrease the profit that’s being enjoyed by big Pharma, creating jobs for people, hospitals, clinics, the taxes collected by the government, the economy will collapse!!!

This also explains balding in older men (not premature balding in 20yr olds). A good scalp vasculature is key to prevent miniaturization, since hypoxic environments promotes the impact of DHT.

David Sinclair is a genius, glad to share this world with him

@asadchoudhrya

4 жыл бұрын

settle down, this is a peripheral part of the aging picture. Light is more important than any other variable when it comes to health.

@clincpb8903

4 жыл бұрын

You are way to quick in calling plain salespeople a genius !

@benabrams849

4 жыл бұрын

@@clincpb8903 Read his book Lifespan...

@michaelqiu9722

4 жыл бұрын

How so? He seems like a garden variety academic to me.

@oldsore

4 жыл бұрын

Why doesn't he back any brands? Can anyone find higher purity or better pricing than donotage.org ?

Quit eating sugar and processed foods

@aregst

3 жыл бұрын

no way to quit sugar and processed foods, cafes, restaurants etc. Most people live in cities. Life will be miserable (like in a lockdown, in a prison). That will kill more people than help. A multi-vector action from many institutions is needed to change the whole lifestyle of industries.

@froesesp

2 жыл бұрын

Quit oil, not sugar.

@andyzhuang3946

2 жыл бұрын

Start eating more organic vegetables and fruits.

@ceraway2276

Жыл бұрын

I did, and somehow even that still isn’t helping the blood flow to my brain.

@prat-man

Жыл бұрын

Quit life

David Sinclair and his team should win a Nobel prize, not only for the research and discoveries they have done on fighting aging, but that he is openly sharing this new knowledge to the world.

@CheerieTM

Жыл бұрын

I totally agree with you.

@prat-man

Жыл бұрын

Not yet

@user-fs8tl7ni1w

2 ай бұрын

Google: GlaxoSmithKline and David Sinclair. You’ll come to know more about David. A lot more.

Essentially, increase NMN intake. I’d stay away from supplements unless they’re pharmaceutical grade. Foods highest in NMN: 1. Broccoli 2. Cabbage 3. Cucumber 4. Edamame 5. Avocado 6. Tomato

@briansprenger5578

4 жыл бұрын

You can eat all these things without being vegan.

@cornstar1253

4 жыл бұрын

@IAM REAL LOL. Every vegan Ive seen looks like a crackhead

@angelhelen84

4 жыл бұрын

Plus, contrasting showers. Going from hot to cold a few times.

@hoofheartedicemelted296

4 жыл бұрын

@J Wil It's not everyone's cup of tea J, but I started taking a Lemon Ginger Blast (not the tastiest thing in the world) for breakfast about 3 months now and I was completely gray hair and my locks and the back of my head is the original colour again, I'm not shitting you I'm being honest. I didn't notice immediately but people started pointing it out and some of my work colleagues even joked about hair colour products. I was due for an ear operation and as part of the pre-op set of tests they checked a number of things including blood pressure (high blood pressure runs in my family) and it had almost returned to normal and the mucus that was trapped inside my ear (eustachian tubes) was almost completely gone. They said they would go ahead with operation if it was my wish but added it was unnecessary given the new results. I don't have shares in vegan products and I don't really care that much who is impressed by me so there is no advantage for my to lie. Try it yourself if you are suspicious. The great Bruce Lee as asked how he was a genius given he was ahead of his time in his chosen field of knowledge, he said "I'm not a genius, I just try everything and keep what works and discard what is useless". So give it a try and be patient to let the results manifest. peace bud.

@hoofheartedicemelted296

4 жыл бұрын

@@cornstar1253 Then supplement with what they are lacking. If their knowledge is incomplete, then fill in the blanks. Don't choose 1 system over another, combine them and experiment and see what works.

This man has changed my life.

@voidmap6628

2 жыл бұрын

How, explain please

Human bodies are an astonishing piece of engineering. Makes me all the more appreciative of the Engineer.

@monnoo8221

Жыл бұрын

there is no engineer. It is evolution. Yet, in order to understand evolution.... well, i better stop, because it gets too complicated

@c-4839

Жыл бұрын

The almighty God in his infinite wisdom,

@monnoo8221

Жыл бұрын

@@c-4839 when d they understand that such nonsense is pure blasphemy, in their own system??? How can you apply sth like "wisdom" here' how can you say "almighty"? How cold you at the same time' It would mean that cruelty is an important part of wisdom. You are stupid, on your wn scale.

@ETz-RYANH.

5 ай бұрын

Natural & evolutionary engineering in a way i write :)

@jamesjirik2245

4 ай бұрын

Human bodies are incredible amount of maintenance unless you’re rich is a real pain in the ass

Thank you dr David ,I just bought your book lifespan !you are my hero! Congrats !

@luislehmann9929

2 жыл бұрын

why we age and why we don't have to. i got it too, this guy mister sinclair is my hero. far from being hungry for profits, he does it so that humanity can benefit from his discoveries

Thats very encouraging news and remarkable that a naturally occuring product in our body would be the catalyst that reinvigorates the others and reverses the condition

David Sinclair you are a genius your theory on epigenetic aging would also explain the cambrian explosion of species as well as aging. Neat when one new theory explains an old conundrum.

2:41 I started a regimen of 1g/day of NMN and 1g/day of resveratrol on 10/1/22. Within two weeks, the lower leg edema that I had been experiencing for several years completely went away. On top of that, my recovery time from daily pickle ball was very significantly shorter, and no more calf muscle pulls. None. I have been on the regimen for roughly two and a half months. I will never stop.

@shanealharbi8664

Жыл бұрын

sweet man!! Super happy for ya! Any side effects?

@Sh0n0

Жыл бұрын

@@shanealharbi8664 yes, one side effect my penus grew 3 inches

@AL_THOMAS_777

Жыл бұрын

@@Sh0n0 Ol´braggart :P

@AL_THOMAS_777

Жыл бұрын

Which BRAND of NMN pease mate !

@RLLUMB

Жыл бұрын

Yes which brand do you use?

Whenever I'm feeling a little too high on endorphins and the wonder of life, I'll come here and watch this video and remember how old I am and how much my body is decaying as I follow life's rut ever more slowly until I'm choked to death by the very systems that brought me life. Cheers 🍻

@RIP5582

4 жыл бұрын

DingbatToast Thanks Ding. 👍

@Devonellah

4 жыл бұрын

And yet you can't see the positive aspects to the research.... interesting... :)

@theonlyantony

4 жыл бұрын

DingbatToast ha! Yes!

@DingbatToast

4 жыл бұрын

@@Devonellah and yet you can't see the humour in my comment?

@roybiden3985

4 жыл бұрын

Before you hate for what I am going to suggest, please understand I am a few thousand miles away from you and there is no reason to hate me. I just would like to suggest that you read the Quraan . Its available online. May Allah bless u with good health and happiness in this world and thereafter.

Dr. Sinclair, Does this research tend to confirm the efficacy of EECP as well? It certainly improves exercise tolerance by mechanical assist to blood velocity, stimulating angiogenesis, and soothing endothelium as well. Have you looked at it's effects on NAD?

@TopVillain

Жыл бұрын

He isn’t answering question

@sleepinglaffey3886

11 ай бұрын

It's probably synergetic on senescent myocytes. -Meat based KD sprinter

David you are a genius. A thousand likes for you.

Which foods have NAD+ and NMN ? Do we need to eat pills now, or is there any food that has those ?

Which brands do you recommend and dose? Thank you for your reply.

Can you comment on the probability of NMN causing inflammation and thus being detrimental rather than beneficial.Thank you.

Great man. We owe him a lot.

I admire such smart people you have a gift

Thank you. Are there any other foods or herbs besides these that increase NMN? 1. Broccoli 2. Cabbage 3. Cucumber 4. Edamame 5. Avocado 6. Tomato

Love it! Thank you, dr. SINCLAIR !!!!!!!!

Wow.. This is great news. David You are great !!!

But,the paper published in 2016 mentioned CD38 could reduce NAD+ And NMN

Omega 3 (Wild Salmon etc) Turns rigid "pipe" shaped vessels back into "hose" shaped vessels.

@johnnyfly1236

4 жыл бұрын

Or better use something that is not contaminated with lead and pcb. Like flax seeds, chia seeds, walnuts.

@DARisse-ji1yw

4 жыл бұрын

But... At my age, I'm happy to have a rigid pipe !

@egreenie3819

4 жыл бұрын

@@DARisse-ji1yw I thought I had a rigid pipe the other day😃. . . . . . . ...but it was just rigamortis setting in😔🥺

@MoneyStrategiesSOULutions

4 жыл бұрын

Johnny Fly : sorry not the same at all. You can get the purified ones.

@xeropunt5749

4 жыл бұрын

Avatar007 True. Calamari DHA purified is pretty good. Omega "pastured" eggs. Frozen Wild Alaskan Salmon burgers from Costco 480 mg of just the DHA, per burger.

Excellent work, Doctor. I'm rooting for you to make an awesome discovery soon.

@soapfan2700

Жыл бұрын

Same here, if anyone can find a less invasive cancer cure or even better a dead certain prevention, then he can.

Thank you, David!!!

You rock Dr. Sinclair!!

So the question is, how does one improve blood flow of tiny blood vessels, as we age in a healthy sustainable way?

@Broxine

4 жыл бұрын

Taking opc

@LifeDIY

4 жыл бұрын

Cold therapy - look up Wim Hoff :)

@LTPottenger

4 жыл бұрын

fasting

@EBIRCSBUS33

4 жыл бұрын

take the herb rosemary the long lived in the blue zone use it on food hence better micro -circulation

@BeLikeWaterBeLikeWater

4 жыл бұрын

I recently researched and found out that after the age of 40 people drop off about 50% in Nitric Oxide production which is responsible for softening the blood vessels making blood flow easier which in turn creates better circulation. To increase NO taking Beet Root powder and Citrulline will bring them back up to optimal levels that you can check at home with Test Strips bought on Amazon. Also discovered that many people are deficient in vitamin K2 not to be confused with just vitamin K. Vitamin K2 is responsible for proper absorption of calcium into our bones, being deficient causes leaching from the bones making the bones weak but the calcium then collects in our arteries (which harden) and kidneys restricting blood flow. Restrict blood flow and a host of problems are created. The good news is it can be reversed naturally. Studies have shown over a 4 week period after taking vitamin K2 the amount of calcification buildup was reduced considerably. So at the end of the day if blood flow isn’t restored over time and because some areas of our body take first priority when blood is rationed the others next in line either get less or none which causes small vessels to die thus causing nerve damage (neuropathy).

Any supplements? Any suggestions among the many brands out there!.

@madchaos4912

4 жыл бұрын

Yes it is called TRU.

@tatsumakisempyukaku

4 жыл бұрын

meygaag kabacalaf I think the drug metformin activates the sirt Genes, MTOR, and one other gene. All of which are fasting and exercise mimicking. NAD does something with that too. I’ve also read that reserveratrol is a fasting mimicker. If you want I can Point you to some good sources that I use.

@versewriter5856

4 жыл бұрын

Whichever one you choose make sure that it contains vitamins that are biologically available in other words 'activated'. If you'd like to know why then please feel free to get back to me.

@tamuman93

4 жыл бұрын

tatsumakisempyukaku - Please share your knowledge. This is fascinating.

@tamuman93

4 жыл бұрын

Verse Writer - Could you please explain what ‘activated’ vitamins are and why they’re important? Thanks

I see that the NMN products on the market have all types of fillers such as starch for absorption I assume. i was wondering if it is safe to take a 99.9% pure form (powder) of NMN straight from its source or does it need to be mixed with other things to be able to be taken in by humans.

Very good info. Love it. Thank you.

Always knew that M&Ms were magical 😋

All the Tour de France winners: "They're still using rats?"

@Darius-lh3ki

4 жыл бұрын

@@donalkinsella4380 :DD

@versewriter5856

4 жыл бұрын

@@donalkinsella4380 😂

@claudermiller

4 жыл бұрын

LOLOL

@aaronreeder5753

4 жыл бұрын

@Alien On a Bike are you suggesting they specifically found elderly mice to trial this on? I'm pretty sure it would work no matter your age. They're too young? Wtf do you know? Lol.

@ibperson7765

4 жыл бұрын

Aaron Reeder Obv youre joking? Or... anyway the video said it only helped old mice.

Any studies on NMN vs NR? Any write ups I have read seem to favor NR.

Have you looked at the Glycocalyx Structure that sits on top of the Endothelial cells and can cause damage 💔 what is your thought?

It's refreshing to see a scientist have a genuine interest in discovery in his field--though not that you can tell from this short video. There are other Harvard scientists, like Wrangham and Willet, who seem to be preoccupied with self-promotion, and science takes a backseat.

No mention about having a high acidic blood versus a balanced ph alkaline blood. 🤔 acidic blood cells are known to be linked to a long list of ailments.

@hadd5106

4 жыл бұрын

How do you know that the blood is acidic? Do you do a lactate test?

@raydematio7585

4 жыл бұрын

This is superstitious nonsense

Might this have a beneficial effect on 'leaking'` blood vessels such as cause Chronic Macular Edema? Asking for a friend ;)

This is amazing!!

It is- so let it be available for all!👍🏻😀😃

What about vitamin K2 ? Does this not help to prevent heart attacks/strokes and restore health to arteries?

@dawnwhitehead

2 жыл бұрын

Absolutely! It directs snd keeps calcium in the bones and teeth where it belongs instead of in the blood where it turns one to stone by stiffening the arteries. This in turn causes strokes snd heart attacks!

Dr.Sinclair, i take DMAE as a supplement and want to add NMN, I cant find any info on compatability. What do you think?

MOST GRATEFUL DEEPLY APPRECIATED

Dear David, Although I found NMN to be a rather strong diuretic that’s sometimes convenient, Nicotinamide Riboside seems to do the trick for me. It’s a little pricey so you can also try regular Niacinamide (Vitamin B3, Niacin) as a NAD+ booster. Along with Resveratrol, it may be the “15 year pill” here for us already!

@lightbeingpontifex

2 жыл бұрын

I do nmn nad resveretrol berberine coq10 and low dose niacin (super itchy and hot),,,

@freespiritwithnature4384

2 жыл бұрын

Hi Gricycle . Do you think this will work on the white scar tissue that is in the teeny blood vessel’s inside of the brain . MRI a yr ago there was some ,now lots . Have autoimmune disorder but what would you recommend I buy to begin with. Lasix is usually not liked by Drs because of diuretic effects, but would you with the Nicotinamide ? Where would I buy this / do you recommend a website ? I thought about Nitic Oxide. What are your thoughts?

@orion9k

2 жыл бұрын

Nicotinic acid is better than nicotinamid

@skittles2055

2 жыл бұрын

@@freespiritwithnature4384 hello dear Spirit, I don’t have specific answer but wanted to send blessings your way. Also, may I recommend Dr. Joe Dispenza’s work 💫 (meditations, books, lectures, testimonials/stories of transformation)

@chunkycheeze1067

Жыл бұрын

Are you and Dr. Sinclair actually so close that you're on a first-name basis with each other, or are you just an American?

Would this also help in people that are already physically fit? Would they be able to perform faster and/or stronger?

@Elayman1

6 жыл бұрын

NMN supplementation didn't do anything for young sedentary mice but did boost exercise capacity in young mice that had been exercising regularly for a month.

Okay, where do we go to get this great stuff???

I lost my youthful mobility due to spine issues. How I wish I can be a part of your clinical trials in the future to help you with data. For the meantime, let me see how I can get that nicotinamide mononucleotide if there are any supplement in our country.

“Health is wealth.” Virgil

Since NMN is a derivative of vitamin b3 (niacin), which I already take, am I covered, or does NMN function differently in the body than niacin does?

@wyattlavigne

4 жыл бұрын

D LG if you dig into it, NMN does some things better, same with NR and ditto on Niacin. Kinda like vitamin K1 can kinda do a bit of K2’s jobs and K2 can kinda do a bit of K1’s jobs, but the body will only limp along if you only have the one form. That is, NMN, NR and Niacin are poor, but not completely useless substitutes for each other.

@wyattlavigne

4 жыл бұрын

aztekkthundergod in which aspect? Mobilizing free fatty acids? Lowering cholesterol into normal ranges? (Niacin’s the gold standard at that almost twice as good as Statins) Promoting proper HDL and LDL levels? Short-term lipolysis/fat-burning? Upping NAD levels? Taking someone pretty much instantly out of an LSD induced state? Curing schizophrenia? Niacin’s a beast. I’m guessing you’re referring to the NAD levels. For me, mega dosing Niacin gave a very negligible boost in energy, suggesting a very low to at best moderate affect on NAD levels.

@dlg5485

4 жыл бұрын

@aztekkthundergod I don't know where you got that information, but niacin most certainly has not been "debunked." As a treatment for existing cardiovascular and other issues, yes, 1500 mg per day or more might be needed, but as a preventive measure to ward against these chronic ailments, even 500 mg per day can be effective. I take 500 mg 2x daily and it has absolutely been effective, helping to keep my cholesterol, blood pressure, blood sugar, etc all in check.

@dlg5485

4 жыл бұрын

@aztekkthundergod I'm not interested in just the studies. It's just as important to know who funded the studies and what interests they have. Pharma companies pay researchers to publish bullshit 'studies' constantly in an attempt to discredit the natural treatments that compete with their drugs, so make sure you're looking for that. In any case, I've done my own research into niacin, numerous times over the years, and I'm more than satisfied with my findings...and, of course, my own experience with it.

@lukeweaver9287

4 жыл бұрын

@aztekkthundergod probably a funded study by the statin drug makers

So the question is what is NMN in simple terms how can you make it available to the random public and is this something we can receive in food, or we'll have to be synthesized?? And what are the long-term effects on someone who would use this NMN??

@lobodo396

2 жыл бұрын

MNM. Is business--> That’s all.

Thank You for your information. Could I share my concern, recent cancer research on NAD level boosting... May 30, 2019, Scientific American, "Cancer Research Points to Key Unknowns about Popular Antiaging Supplementz", by Helen Shen. I was confused to read that article. Is it possible that NAD Boosting can lead to cancer? - Choi -

Any theories why NMN increases the vividness of my dreams?

@Cherub72

3 жыл бұрын

this stimulates cell regeneration as well and helps red bloods cells. I'm guessing you're able to get more and process more oxygen using this

@RodCornholio

3 жыл бұрын

@@Cherub72 OK

Update on my previous comment: It's not the isosrbide mononitrate causing the effects mentioned below, it's Atorvastatin. I noticed my best results from NMN was when taking around 100mg per day from a good supplier, but these effects decreased at hgher doses. Due to running out of Atorvastatin, I was off them for a week to find 1g doses of NMN kicked in again, but decreased effects once I started the statin again. Also, taking statins and NMN at 1g causes statin side effects. I need statins to decrease cholestorol, have had a stroke and have heart disease, but it seems that I need less NMN when taking Atorvastatin. Do you have any information on interactions between the two?

@orion9k

2 жыл бұрын

I've just received my batch of nmn, taken 200 mg for two days now but I'm very sceptical because it taste strongly of lemon with a slight taste of amphetamine.. I mean, if they are adding amphetamine to this, no wonder people feel energized when they take large doses ..

@catman4471

2 жыл бұрын

@@orion9k NMN does taste slightly lemony. If you've purchased from a reliable supplier you've got nothing to worry about. Also, you should experiment with doseage as guidelines vary from around 250mg to 1g per day. Your current age and health contribute to the amounts you might need. If you're over 50 you're nad levels are possibly 50% lower than when you were younger, but again that also depends on your current state of health, diet and exercise routine.

@orion9k

2 жыл бұрын

@@catman4471 Thanks for your reply. So I got my NMN along with B3 Niacin (Nicotinic Acid, the one with flush which I actually find pretty awesome) and also B6. The B6 made me feel completely weird so I stopped that after taking 25 mg morning and 25 again afternoon, I felt really on the verge/borderline of psychosis... The B3 nicotinic acid really gives a positive effect, I feel warm and slightly more energetic when I take it. The NMN still hasn't done much for me, I took 300 mg today, but I will keep increasing dose. I just bought Creatine today as well, heard a lot positive stuff about that too. I'm 37, I weight lift 2 hours 3 times per week, I try not to overeat with carbs and proteins even thou many promotes this when weight lifting, I think I'm around 1800 calories per day and around 80-90 grams of proteins, I'm 182 tall and 70 kilo. I also eat a lot of oils like MCT, Olive and Fish oil, I'm getting like +1 gram of DHA and also taking magnesium, zinc, MSM, Spirulina tablets, 5000 units of d vitamins with k2 added and between 6000 and 8000 mg vitamin C per day (2000 mg in the morning and per meals/smoothies) which actually has helped to make my sun allergy and long recovery time from weight lifting go away, but I have no idea what levels my NAD is, I just know that I'm trying to get my energy levels up, I'm tired all the time and my brain is foggy a lot through out the day, I've become very stress sensitive since 2019, so I'm trying everything I can to get my shit together.

@catman4471

2 жыл бұрын

@@orion9k Hi, NAD levels start decreasing around age 35 so you won't really notice much of a difference especially as you're getting ample exercise. You might like to look into taking Berberine though, around 900mg in 2 or 3 doses spread throughout the day, but not on days that you exercise. It helps with energy and muscle definition amongst other things such as stress and brain fog.. I like flush Niacin and often take between 500mg to 1 gram depending on if I've run out of NMN or not, and I take it in the evenings as it helps me sleep once the flush has gone. If you have health issues then you might like to think about gradually increasing the NMN until you find a level that suits you, but if otherwise healthy you should stick to a lower dose just as a top up for now seeing as you have already purchased some, but you could save the expense for another few years. Vitamin D Complex is excellent too, so you should be doing alright with your stack.

@dolores397

Жыл бұрын

All my best to your health! Keep it up

Not sure what everyone is using in terms of a brand, and I thought I share my experiences with NMN supplements. I have been using NMN for about 11 months, I am a 68-year-old male and I have tried over 20 different brands. The only one that seems to work for me personally is Probase Nutrition NMN Powder, simply because they are a well-known California brand, and I had their NMN independently tested for purity and impurities. Theirs came in at 99.89% purity and had zero lead in it. It seems some people on here have used Probase (the brand) NMN as well and they seem to be happy as well. Hope this helps!

Thank you always David! The world and myself especially appreciate all you do.

Any update from the clinical trials?

@laurieparis2203

4 жыл бұрын

@@markobabic487 Thanks! Looks like they moved the completion date up to June 1, 2020.

@ipponsuki

4 жыл бұрын

Yes. Intermediate fasting and dark uncooked greens.

@klam77

4 жыл бұрын

@@markobabic487 how do they ADMINISTER the Nicotinamide Mononucleotide

@bsxboy

4 жыл бұрын

@@markobabic487 Marko, od kje prihajas?

@MigsWasHere

4 жыл бұрын

What about now?

So beautiful, thank you professor for this amazing information.❤️

@T9RX3

4 жыл бұрын

What are you going to do with the information?

@annetteyoutube742

2 жыл бұрын

@@T9RX3 Dr Patrick will surely tell you 😘 She's interviewing this doctor: kzread.info/dash/bejne/Z3ioudOzkc-rnsY.html

FANTASTIC WORK.HOPE THIS WILL BE AVAILABLE TO US IN INDIA WHEN I AGE!!!

Hello doctor, is there a treatment for a person with a stroke in the brain in the behavior area? Do you have any treatment?

@mrsm3442

3 жыл бұрын

Yes, please, consider this molecule for stroke. I had massive neurological problems and I felt a difference from the first week I used it, after many years of struggling to get well.

He is looking younger in this compared to how he looks now. Wonder if the NMN and Resveratrol he is taking is actually working as well as he claims..

@orion9k

2 жыл бұрын

Resveratrol does nothing

@DK-ox7ze

2 жыл бұрын

@@orion9k Even NMN and NR doesn't do anything. I have tried them both.

@orion9k

2 жыл бұрын

@@DK-ox7ze what doses? Everybody on KZread who does reviews on nmn says it works really well but there has been a lot of fake nmn products on Amazon as I've heard, maybe you had a fake product ?

@orion9k

2 жыл бұрын

@@DK-ox7ze I just got my nmn today, 15 gram ✔

@DK-ox7ze

2 жыл бұрын

@@orion9k From where?

Any worry that increasing SIRT1 would be potentially carcinogenic?

I wonder can you help me. If I were to purchase a supplement which one should I choose disregarding price - NR, NAD or NMN? It's very confusing as to which one to buy for maximum benefit.

@gguniiit2953

5 жыл бұрын

Neil A D NMN is metabolized to NAD so buy NMN or any supplement that increases NAD

@Mistyfire

5 жыл бұрын

@@gguniiit2953 Sure, It's super expensive buying this retail so I was getting quotes from China. Just can't be sure the product is any good though

@jayashri6373

4 жыл бұрын

@@gguniiit2953 my mom had stroke few years back.can i give her NMN for her ,bcoz shes having mitral value disease for which she underwent minor surgery 2 years ago ..can i have your contact number for further enquiries

NMN = Nicotinamide mononucleotide- It's an over the counter supplement for those of you wondering.

@shahin6671

4 жыл бұрын

Vitamin B3?

@UrbanClimber

4 жыл бұрын

Or nad+

@sandrastirling5840

4 жыл бұрын

Wtf is that ???????

@merson812

4 жыл бұрын

Thank you do much.

@jameslucas5590

4 жыл бұрын

And how much of this NMN do you have to take for it to be effective?

When is that tooth regeneratig gel coming out?

@nerblebun

4 жыл бұрын

Dabayare: The patent was most likely bought by a group of wealthy Dentists, and sits on a shelf collecting dust....never to be released. The money is in the treatment, not the cure.

@Ashok.Vaidya

4 жыл бұрын

Dabayare it call Vitamin K2

@pikiwiki

4 жыл бұрын

this is what i'm waiting for

@gf4353

4 жыл бұрын

Yeah, what ever happened to it.???

@Dogbertforpresident

4 жыл бұрын

It would destroy the dental industry.

Any update...🤔🤔🤔

Brilliant, thanks.

The calves are the second heart . Skipping makes the calf muscles really pump .

@chrispayne750

5 жыл бұрын

How are the calves the 2nd heart?

@ShaunRL

5 жыл бұрын

@@chrispayne750 Because the ass is the second brain.

@swisstrader

5 жыл бұрын

Huh??

@laurieparis2203

4 жыл бұрын

@@chrispayne750 the calves are the second heart, bc they help the veins return blood to the heart.

@jenniferbeatty7545

4 жыл бұрын

@@aqualane1 Train yourself to let go and stop caring what others think. Most would just think you're silly or crazy but screw what they think! You may free others by doing so ...

"With age, the body loses its capacity to make a key element of energy production called NAD (nicotinamide adenine dinucleotide) ... Past research also has shown that NAD is not effective when given directly to mice so the researchers sought an indirect method to boost its levels. To do so, they only had to look one step earlier in the NAD supply chain to a compound called NMN (nicotinamide mononucleotide) ... The researchers found a variety of beneficial effects of NMN supplementation, including in skeletal muscle, liver function, bone density, eye function, insulin sensitivity, immune function, body weight and physical activity levels. But these benefits were seen exclusively in older mice ... When we give NMN to the young mice, they do not become healthier young mice," Yoshino said. "NMN supplementation has no effect in the young mice because they are still making plenty of their own NMN ... Some tumor cells are known to have a higher capability to synthesize NAD, so we were concerned that giving NMN might increase cancer incidence," Imai said. "But we have not seen any differences in cancer rates between the groups." www.sciencedaily.com/releases/2016/10/161027122047.htm Source of NMN on Amazon: www.amazon.com/gp/product/B079S3XF4H/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1

@crobinso2010

4 жыл бұрын

Thank you. That was more informative than the video and took a fraction of the time

@nantucket897

4 жыл бұрын

John Linsky look at history it will tell you whose more violent.

@asuraacademy2739

4 жыл бұрын

You are good as gold 💯

@GlossaME

Жыл бұрын

What's the role of Niacin in this?

Can NMN lead to higher cancer rates in humans due to the timing and activation of NMN? What about methylation?

Keep it up researchers, you're doing fine!

I love mnm”s with peanuts

@davydiver

4 жыл бұрын

😂

@colinmaharaj

4 жыл бұрын

As expected

@FINDINGFITNESS101

4 жыл бұрын

Good joke, but he he clearly meant Eminem, the rapper!

@orbs1062

4 жыл бұрын

🤪 And I prefer plain.

@klam77

4 жыл бұрын

OMG Nmn confused with mnms. It reminds me of old commercial:" I said I wanted a bud light" intern: " you mean not bulb light.?!"

September 2022 big studies are out! Glycine and NAC given together even at doses up 10-15gm daily had very impressive results, no patients reported any side effects. How both work together was a surprise, the the many research studies concluded they work, and well.

@Czy_dni_do_konca

Жыл бұрын

1can you please share this study?

@stilllearning7434

Жыл бұрын

Here is the link to a small study of 8 older adults By Baylor University. Thanks Caleb Veloz. www.ncbi.nlm.nih.gov/pmc/articles/PMC8002905/pdf/CTM2-11-e372.pdf sorry, but is free and copy and paste works

@larsnystrom6698

Жыл бұрын

@Caleb Veloz The way NAC (N-Acetylcysteine) and Glycine works are as precursors to Gluthathion, which is the cells most aboundant antioxidant. The level of Glutathion is reduced with age. So it's probably good to try to keep it up. To supplement with these two precursors is more efficient than supplementing with Glutathion itself! It wouldn't suprise me if Glutathion would keep some of the NAD+ consumers in check. Anyway, it can't hurt!

By watching ads, this channel gets more views & support. Tnx.

Great works! the best Resveratrol and NMN is coming out now.

Awesome doing a gram a day. trying not to die till after 3020 . thanks!

@PotBotorg

4 жыл бұрын

@God 2 God the only thing I need is health happiness and love. Without any of those life ain't worth living . To those three things I'm addicted

@abyssmanur3965

4 жыл бұрын

Weed dilates the blood vessels, works for me ...58 and going strong, strong enough to take up gymnastics.

@tamuman93

4 жыл бұрын

Patrick Foley - Al Gore invented this thing called the Internet. It’s wonderful! You might get a book and research it! You’ll be fascinated. 😁

@robertgoldstein52

4 жыл бұрын

Another useless Md

@sfguy2000

4 жыл бұрын

@@pbfoley amazon

I have read / been told about so many medical breakthroughs at the research stage. I even saved or scrap-booked the ones that interested me. Over 20 years, not one has actually helped a human. I really don't understand medical research. I think publishing papers is their sole objective.

I truly believe he will!

Will this help resolve an arterial aneurysm?

Nicotinamide Mono Nucleotide (NMN) in DNA & RNA. The weird thing is they say you have to take NR or NMN etc to get NAD, you don’t. You can take full flush Nicotinic Acid (Niacin) & it converts minimum 30% into NAD. The more significant thing is to learning take Full Flush Immediate Release Nicotinic Acid. You start with 100mg & titrate to 1000mg or 1500mg to get decent NAD. I did this rather inconvenient experiment & now reached 1500 mg after great struggle that I do not regret one bit. Nicotinic Acid is life savior for me & my lipid panel has improved significantly.

@Daughter-OfTheKING

4 жыл бұрын

Madison One I was diagnosed with almost a 50% blockage in my carotid arteries and was prescribed 1500mg Niacin by my naturopath. My doctor had no solutions or treatment for me other than suggesting I “pop in once in a while and have my blood pressure checked.” If I was not warned about the severe flush I would have ended up up in the ER. Scariest and the most unpleasant experience. Needless to say after a while I stopped taking it because of the flush. I will try your approach. Thank you.

@marieholoub4084

4 жыл бұрын

I have tried to take it many times at 100mg but each time without a fail I get headaches....

@madisonone8929

4 жыл бұрын

Yvette - There are numerous strategies to taking Nicotinic Acid. You need 32 Oz of water, apple sauce, quercetin 500 mg pill & fish oil. After dinner go for walk then an hour before bed pop quercetin after 20 minutes follow by Nicotinic Acid pills, fish oil with Apple Sauce, squeeze packets are convenient. Drink first 16oz water when you experience initial tingling of flush then you drinking the other 16oz get the Nicotinic Acid moving. It takes 1.5 hours to fully move it after you swallowed. Also eating salad with dinner helps salads have quercetin which suppress prostaglandin d2 that causes flush. But flush is good, that’s when the body pulling out all the bad cholesterol out & boosting HDL. After a certain time you won’t experience flush & then a day off Nicotinic Acid & get back on it. The flush will come back. Flush is the secret to long healthy life. It’s not an allergy. There are no known case of anyone dying from flush. But this is something you have to titrate into slowly. Nothing to be panicked.

@Daughter-OfTheKING

4 жыл бұрын

Madison One thank you so much for taking the time to respond. I will definitely consider your suggestions. Much appreciated 🙂.

@Daughter-OfTheKING

4 жыл бұрын

Donal Kinsella I have not tried but I will educate myself on it and definitely consider it. Thank you

Sounds great. Amazing work! But it will likely have side effects that need to be watched out for.

Thanks again.

I've started NMN supplements recently along with TRT hope things get better.

Amazing what botox and 'back to black' hair spray can do!

@littlekimmy676

4 жыл бұрын

lol!!

@v.r.2834

4 жыл бұрын

Yes, indeed, I just taught that he used some „ help“ on his face and hair 😂

@Lance2773

4 жыл бұрын

The hair is brown.

I can be a "mouse" for you in a future NMN study. I already run on a treadmill. :)

I'm ready for the pill Doc!

Where can we get these medicines?

Elena, I took even more, and I haven't even been born yet; I'm just a twinkle in my fathers eye.

Niacin (which gets converted into nmn) naturally occurs in Broccoli and Cabbage. The average vegetarian isn't living exceptionally longer than anyone else. I think it is less effective than is being claimed by people who have a vested interest in profiting from the boom in sales their hype generates

For Autoimmune can we take NMN ?

So you’re making pharmaceuticals

@KekeeBlack

4 жыл бұрын

Jason Lynch he’s going that route because supplement companies scam people a lot. I kind of wish he wouldn’t but whatever.

@JaysonT1

4 жыл бұрын

@@KekeeBlack Like Pharmaceuticals don't scam people?

And 🤓??? 🤔 what’s the fringing solution 🙄🙄🥴

@ldld64

4 жыл бұрын

I know right ! I was waiting for it , BUT THE VIDEO ENDED !!

@OneironauticalOne

4 жыл бұрын

He said it, NMN supplement. It boosts NAD levels and helps improve muscular blood vessel growth in older individuals.

@digimom82

4 жыл бұрын

@@OneironauticalOne what is MNM?

@OneironauticalOne

4 жыл бұрын

@@digimom82 nmn nicotinimide mononucleotide google it.

@emh8861

4 жыл бұрын

FASTING and its FREE!

Does anyone know if taking NMN increases methylation if you have the MTHFR heterozygous gene

@lukeweaver9287

4 жыл бұрын

@@donalkinsella4380 Moringa is as good if not better, cheaper and easier to grow large quantities of. Broccoli sprouts are a good second choice or during winter or cold climates.

@lukeweaver9287

4 жыл бұрын

@@donalkinsella4380 from Fahey: "Moringa contains a powerful isothiocyanate known as moringin, which is just as potent as sulforaphane, and in some assays actually more potent.". He also said he drinks 2-3 cups of Moringa tea per day. I have 30' tall (as well as shorter) Moringa trees in my yard that grow like weeds with no care or freezer or jars or counter space or multiple rinsing or blending required. There is a reason they call it the miracle tree. I grow Neem as well, which is also nicknamed The Village Pharmacy. (I add various sprouts including broccoli and sunflower to my daily vegetable juice as well.)

@lukeweaver9287

4 жыл бұрын

@@donalkinsella4380 I don't think it would thrive indoors, but a greenhouse will work fine. I am in Florida and it grows great here. Even if it freezes back to the ground in the winter, it comes back like gangbusters in the spring, growing 8 to 10 feet within a couple of months. Even more impressive is the Ube yam which grows faster than Kudzu! It has super health benefits as well. I eat the leaves off the vine, and in salads.

isn't NMN the same thing as niacinamide? Except for the price tag of course

So the answer is more medicine??? Medicine is treatment, not a cure. Show me someone who finds a cure, and I'll show you a real doctor.

@azycray4801

4 жыл бұрын

There is no cure for aging, but you can slow it down. If NMN is made by the body then I wouldn't call it medicine, perhaps supplement would be a more accurate term. There are many supplements you can take to slow down aging. NMN is one of them which is fairly expensive. But what the hay, you can't take it with you so if not well spent, at least not wasted. I consider it an investment in quality of life.

@Dogbertforpresident

4 жыл бұрын

I think geneticists would have to find a gene (or make one) that allows our cells to produce NAD at the necessary level to remain biologically young. That would be a cure.

@annabelalford804

4 жыл бұрын

@@Dogbertforpresident the NMN affects the epigenetics of your mitochondria in your cells. So, it turns off or on certain genes that make you age. So....

@jeremyanderson6789

3 жыл бұрын

There is a cure for aging!

and what natural foods contain these special molecules?....the good doctor's point of view caters for the pharmeceutical industry

@Spark-In-The-Dark

4 жыл бұрын

ukidding, of course he does. Harvard “elitists” aren’t trying to help the general population. They think we’re cattle.

@tazboy1934

4 жыл бұрын

Keto plus IF

@wrchmura

4 жыл бұрын

Edamame broccoli cabbage cucumber avocados and tomatoes

@megaswenson

4 жыл бұрын

@@tazboy1934 Precisely what I was thinking,

@T9RX3

4 жыл бұрын

It's called exercise.

To short . This nan us a genius! But where has he gone ?

@LaRoucheisright

4 жыл бұрын

Google algorithms make sure the truth reaches as few people as possible.

NAD 600mg caps gave me horrible headaches. Switched to DMG, no prob, then I started taking TMG 1000mg in morning and 1000 mg in the afternoon. It's helped me so far.

@orion9k

2 жыл бұрын

Why tmg? What it helped with

@larsnystrom6698

Жыл бұрын

@Nifty Nan The reason to take TMG (TriMethylCystein) is usually to supply the body with extra Methyl groups. When the body gets rid of excessive vitamin B3, it consumes Methyl groups. (>Reference Chris Masterjohn). The Glycine is just an extra bonus if you also take NAC. Taking NAC usually doesn't cause any problems. But it's just the Cysteine you want. And if you get enough from your Protein, maybe that's enough. The research has so far been made with very high doses of NAC and Glycine. Suprisingly high doses! It would be nice to know how much you really need. I'm beginning to suspect that much of the problem with Glutathion is caused simply by older people not getting enough of protein. They might need 1.2 g/kg bodyweight. And not the RDA of 0.8 g/kg.

Who wants to live forever?

@Adammk1974

4 жыл бұрын

me

@gf4353

4 жыл бұрын

It would give me a chance to finish my. To do list

Or you could intermittent fast, block fast and reduce carbs which costs nothing in fact you save by not eating periodically.