Retrosynthetic Analysis

These are the hardest problems! You have to think backwards in time? What am I, H. G. Wells?! Relax, friend. You just have to dismantle the target molecule in strategic ways that make sense because of the synthetic transformations you have in your bag of tricks. Give this a gander and you'll see.
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Пікірлер: 58

  • @MrHappyface198
    @MrHappyface1987 жыл бұрын

    I appreciate the work you put into these videos, unfortunately i still suck at organic lol.

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    7 жыл бұрын

    practice, practice, practice!

  • @metiburussie8973

    @metiburussie8973

    2 жыл бұрын

    Love the honesty because same, lol!

  • @PowerSuitNinja
    @PowerSuitNinja8 жыл бұрын

    Hey Professor Dave! Thanks so much for all your help with Orgo 1 and 2 this year! Your concept videos were awesome. Wouldn't have been able to get though it successfully without your help!

  • @abhishektiwari7643
    @abhishektiwari76433 жыл бұрын

    Whenever I need a little brush up of any concept ,your videos help me out Good job pro

  • @imbatmanlol
    @imbatmanlol Жыл бұрын

    Only part of organic chemistry that dare I call, “fun”

  • @BangMaster96
    @BangMaster964 жыл бұрын

    This is like a top down approach, you start from the finished product, and derive its components.

  • @ranjanpaudel698
    @ranjanpaudel6986 жыл бұрын

    thank u sir...really appreciated ur vid....its goin to help me in my xms...

  • @ivanbombana7282
    @ivanbombana72824 жыл бұрын

    very beautiful….. do you have other videos like this? With much more complex molecules?

  • @abhisheknair5630
    @abhisheknair56307 жыл бұрын

    Your videos help a lot..Thank you so much.

  • @TheBalls55
    @TheBalls555 жыл бұрын

    Professor Dave finds lots of " medicinal" compounds in nature.

  • @tyriqcleo5899

    @tyriqcleo5899

    3 жыл бұрын

    Weed

  • @gauthamkrishna
    @gauthamkrishna7 жыл бұрын

    this is really helpful,thanks as I did not understand this in wikipedia and quora thanks!!😁😁👍👍

  • @helmifauzi2669
    @helmifauzi26696 жыл бұрын

    love it so much, so helpfull thank you from Indonesia

  • @youtubeedchannel1730
    @youtubeedchannel1730 Жыл бұрын

    Can you do an excercise to obtain a heterocycle compound? Thanks for your content

  • @apurbamondal3725
    @apurbamondal37256 жыл бұрын

    Thank you sir ...for helping me out

  • @user-md1uq8nz6i
    @user-md1uq8nz6i7 жыл бұрын

    thank you so much

  • @Amy-se5ld
    @Amy-se5ld7 жыл бұрын

    Can you do retrosynthesis for aldol condensation reactions?

  • @user-de4uw7lz9n
    @user-de4uw7lz9n5 жыл бұрын

    Thank you very much!

  • @tealwalters990
    @tealwalters9905 жыл бұрын

    Thank you!

  • @xXRachelClaireXx
    @xXRachelClaireXx5 жыл бұрын

    Have you ever considered doing meet and greets in CA professor Dave? Love your videos!!

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    5 жыл бұрын

    i would be up for it! but who is it that would want to meet me?

  • @Politickticktickin

    @Politickticktickin

    5 жыл бұрын

    @@ProfessorDaveExplains Haha she wants the D and you want Rachel's P LOL

  • @ravindrnathsstories2505
    @ravindrnathsstories25056 жыл бұрын

    Which book is best for retro synthesis please advise sir

  • @kevinsoun3030
    @kevinsoun30307 жыл бұрын

    For the first reaction, should we use MgCl? When you radically halogenate the propyl group with Br, it is more selective for the secondary carbon and that would yield a different product. We should use Cl because there is only a negligible difference between the selection of a primary vs secondary carbon??

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    7 жыл бұрын

    i'm not sure what you're asking, if it's for the grignard one, from the starting material we use PBr3 to go from alcohol to alkyl bromide, so there is no radical halogenation.

  • @mosuputsasuzanne3905
    @mosuputsasuzanne39052 жыл бұрын

    You're the best...understood

  • @shubhampal8754
    @shubhampal87546 жыл бұрын

    You are a super hero!!!

  • @shyamlokhande3466
    @shyamlokhande34666 жыл бұрын

    Its really helpful......

  • @tantech2769
    @tantech27694 жыл бұрын

    Thanks!

  • @nivedithag8427
    @nivedithag84274 жыл бұрын

    sir ,could you please post a video on synthesis of peptides by sheehan's method

  • @ahmedkhlifi9266
    @ahmedkhlifi92665 жыл бұрын

    I have a restrosynthetic synthesis exam can you help me with some links that could guide me please

  • @ananuraidaputri9298
    @ananuraidaputri92987 жыл бұрын

    Thank you Sir for this information

  • @jdubzz9812
    @jdubzz9812 Жыл бұрын

    could we just react the DB at 6:30 ish with 2 equivalents of O3 to create two ketone groups and turn those into alcohols with NaBH4 to create our alcohols?

  • @misskaruna6854
    @misskaruna68545 жыл бұрын

    Pls give me the name of refrance book for parcticing retrosynthetic analysis........

  • @roxygaming437
    @roxygaming437 Жыл бұрын

    Thank you so much sr♥️♥️♥️

  • @mattikore5796
    @mattikore57963 жыл бұрын

    Sir what is the synthetic equivalent of co groups tell me

  • @kevinsoun3030
    @kevinsoun30307 жыл бұрын

    And also, why do we need to use PCC if the grignard reagent already kicks out the double bond with the O--thus making it OH??

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    7 жыл бұрын

    again not sure i understand, PCC is needed to go from ethanol to ethanal. remember that the retrosynthetic arrows are not forward arrows, they go backwards, each arrow leads to the precursor of what you're looking at, so the alcohol came before the aldehyde, it's not that we are reducing an aldehyde to the alcohol.

  • @tesfayeayisa1253
    @tesfayeayisa12532 жыл бұрын

    thanks

  • @davidgamez-alvarez5701
    @davidgamez-alvarez57017 жыл бұрын

    Why couldn't just start the first one as 1-pentene and reacted that with H20 and H2SO4?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    7 жыл бұрын

    it says starting from molecules with three carbons or less!

  • @Natalie-yv2go
    @Natalie-yv2go6 жыл бұрын

    Is there a good place to drill these practice problems? I've taken a look at your practice problem videos. I've also searched and found some practice sheets, but they aren't really enough for me. Is there a site or app that would give me problem after problem for me to practice?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    6 жыл бұрын

    hmm i dunno of any!

  • @marooshmirza9440

    @marooshmirza9440

    5 жыл бұрын

    Kindly give me the link of that practice problem video

  • @virgovirgo9367
    @virgovirgo93675 жыл бұрын

    Hi there genius! Please help me solve a query in organic chemistry.... Please... "RUTIN" or "Rutoside" is a bioflavonoid with the formula C27-H30-O16, it is found in plants like Buckwheat and eucalyptus.. My question is.. " Is it possible to manufacture "RUTIN" synthetically in a lab? without actually using the plant extracts.

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    5 жыл бұрын

    I'm sure it is possible, we can synthesize almost anything, but I'm not good enough a synthetic chemist to come up with a pathway for something like that.

  • @virgovirgo9367

    @virgovirgo9367

    5 жыл бұрын

    @@ProfessorDaveExplains jeez! You replied to me... God bless me.. after all these subscribers, you got time to respond comments.. that's cool. That's pretty cool. Good luck.. I'm Sam. We shall talk again if you believe in " chemical genysis" . 😐. I know it sounds crazy, see ya. Tada.!!

  • @AgamKaushiksowow
    @AgamKaushiksowow7 жыл бұрын

    how do i know which reaction to apply when doing organic conversions ?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    7 жыл бұрын

    depends what you have and what you wanna get

  • @johnemochejames2503

    @johnemochejames2503

    3 жыл бұрын

    @@ProfessorDaveExplains please i sent you a mail.can you reply please

  • @Alex_Van
    @Alex_Van5 жыл бұрын

    What about use of retrosyntesis method to make cyclic compunds?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    5 жыл бұрын

    the approach would not be any different

  • @FatBellyChemist1234
    @FatBellyChemist12342 жыл бұрын

    If I had looked at this earlier I would have done Honours by now.

  • @vlogsbydanielle4045
    @vlogsbydanielle40452 ай бұрын

    bro is Noah Kahn if he was a chem god

  • @akramraza8361
    @akramraza83616 жыл бұрын

    Best

  • @irfanashraf3848
    @irfanashraf38487 жыл бұрын

    slaam sir

  • @ballaki
    @ballaki Жыл бұрын

    👍❤