Retrosynthetic Analysis
These are the hardest problems! You have to think backwards in time? What am I, H. G. Wells?! Relax, friend. You just have to dismantle the target molecule in strategic ways that make sense because of the synthetic transformations you have in your bag of tricks. Give this a gander and you'll see.
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Пікірлер: 58
I appreciate the work you put into these videos, unfortunately i still suck at organic lol.
@ProfessorDaveExplains
7 жыл бұрын
practice, practice, practice!
@metiburussie8973
2 жыл бұрын
Love the honesty because same, lol!
Hey Professor Dave! Thanks so much for all your help with Orgo 1 and 2 this year! Your concept videos were awesome. Wouldn't have been able to get though it successfully without your help!
Whenever I need a little brush up of any concept ,your videos help me out Good job pro
Only part of organic chemistry that dare I call, “fun”
This is like a top down approach, you start from the finished product, and derive its components.
thank u sir...really appreciated ur vid....its goin to help me in my xms...
very beautiful….. do you have other videos like this? With much more complex molecules?
Your videos help a lot..Thank you so much.
Professor Dave finds lots of " medicinal" compounds in nature.
@tyriqcleo5899
3 жыл бұрын
Weed
this is really helpful,thanks as I did not understand this in wikipedia and quora thanks!!😁😁👍👍
love it so much, so helpfull thank you from Indonesia
Can you do an excercise to obtain a heterocycle compound? Thanks for your content
Thank you sir ...for helping me out
thank you so much
Can you do retrosynthesis for aldol condensation reactions?
Thank you very much!
Thank you!
Have you ever considered doing meet and greets in CA professor Dave? Love your videos!!
@ProfessorDaveExplains
5 жыл бұрын
i would be up for it! but who is it that would want to meet me?
@Politickticktickin
5 жыл бұрын
@@ProfessorDaveExplains Haha she wants the D and you want Rachel's P LOL
Which book is best for retro synthesis please advise sir
For the first reaction, should we use MgCl? When you radically halogenate the propyl group with Br, it is more selective for the secondary carbon and that would yield a different product. We should use Cl because there is only a negligible difference between the selection of a primary vs secondary carbon??
@ProfessorDaveExplains
7 жыл бұрын
i'm not sure what you're asking, if it's for the grignard one, from the starting material we use PBr3 to go from alcohol to alkyl bromide, so there is no radical halogenation.
You're the best...understood
You are a super hero!!!
Its really helpful......
Thanks!
sir ,could you please post a video on synthesis of peptides by sheehan's method
I have a restrosynthetic synthesis exam can you help me with some links that could guide me please
Thank you Sir for this information
could we just react the DB at 6:30 ish with 2 equivalents of O3 to create two ketone groups and turn those into alcohols with NaBH4 to create our alcohols?
Pls give me the name of refrance book for parcticing retrosynthetic analysis........
Thank you so much sr♥️♥️♥️
Sir what is the synthetic equivalent of co groups tell me
And also, why do we need to use PCC if the grignard reagent already kicks out the double bond with the O--thus making it OH??
@ProfessorDaveExplains
7 жыл бұрын
again not sure i understand, PCC is needed to go from ethanol to ethanal. remember that the retrosynthetic arrows are not forward arrows, they go backwards, each arrow leads to the precursor of what you're looking at, so the alcohol came before the aldehyde, it's not that we are reducing an aldehyde to the alcohol.
thanks
Why couldn't just start the first one as 1-pentene and reacted that with H20 and H2SO4?
@ProfessorDaveExplains
7 жыл бұрын
it says starting from molecules with three carbons or less!
Is there a good place to drill these practice problems? I've taken a look at your practice problem videos. I've also searched and found some practice sheets, but they aren't really enough for me. Is there a site or app that would give me problem after problem for me to practice?
@ProfessorDaveExplains
6 жыл бұрын
hmm i dunno of any!
@marooshmirza9440
5 жыл бұрын
Kindly give me the link of that practice problem video
Hi there genius! Please help me solve a query in organic chemistry.... Please... "RUTIN" or "Rutoside" is a bioflavonoid with the formula C27-H30-O16, it is found in plants like Buckwheat and eucalyptus.. My question is.. " Is it possible to manufacture "RUTIN" synthetically in a lab? without actually using the plant extracts.
@ProfessorDaveExplains
5 жыл бұрын
I'm sure it is possible, we can synthesize almost anything, but I'm not good enough a synthetic chemist to come up with a pathway for something like that.
@virgovirgo9367
5 жыл бұрын
@@ProfessorDaveExplains jeez! You replied to me... God bless me.. after all these subscribers, you got time to respond comments.. that's cool. That's pretty cool. Good luck.. I'm Sam. We shall talk again if you believe in " chemical genysis" . 😐. I know it sounds crazy, see ya. Tada.!!
how do i know which reaction to apply when doing organic conversions ?
@ProfessorDaveExplains
7 жыл бұрын
depends what you have and what you wanna get
@johnemochejames2503
3 жыл бұрын
@@ProfessorDaveExplains please i sent you a mail.can you reply please
What about use of retrosyntesis method to make cyclic compunds?
@ProfessorDaveExplains
5 жыл бұрын
the approach would not be any different
If I had looked at this earlier I would have done Honours by now.
bro is Noah Kahn if he was a chem god
Best
slaam sir
👍❤