Regulation of Gene Expression: Operons, Epigenetics, and Transcription Factors

We learned about gene expression in biochemistry, which is comprised of transcription and translation, and referred to as the "central dogma" of molecular biology. But how is this process regulated? How does a cell know which genes to express and when? Well it's pretty complicated, but let's just get our feet wet by looking at operons, epigenetics, and transcription factors!
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Пікірлер: 322

  • @JC-xk8vh
    @JC-xk8vh6 жыл бұрын

    There should be a KZread university and all the best KZread Professors should teach there. You Sir would be one of them.

  • @carlycutegirl

    @carlycutegirl

    5 жыл бұрын

    Agreed

  • @abdourahmanjallow9308

    @abdourahmanjallow9308

    5 жыл бұрын

    agreed

  • @alexdeschipper

    @alexdeschipper

    5 жыл бұрын

    disagreed, he didn't mention one protein/one gene

  • @alexdeschipper

    @alexdeschipper

    5 жыл бұрын

    I'm sorry he did give example of genes but it hardly scratched the surface of different regulation of gene expression, where are all the lncRNA, miRNA, siRNA, different histone deacetylases and (de)methylases, cytosine methylases. No mentioning of tissue specific promotors, I don't know it just felt like a lot was missing

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    5 жыл бұрын

    @@alexdeschipper it's an introduction to the topic.

  • @ProfessorDaveExplains
    @ProfessorDaveExplains5 жыл бұрын

    Hey everyone, at 9:34 I drew a methyl group under the word acetylation and an acetyl group under the word methylation, sorry for this ridiculous error! Please correct in your minds. Oh also, I've been informed that at around 1:50, even though the labels have disappeared by that point, I previously marked the mRNA as 5' on the left and 3' on the right, and ribosomes read mRNA molecules 5' to 3', so technically the ribosome should have translated the mRNA left to right. Sorry for that small error as well!

  • @younanoah8229

    @younanoah8229

    5 жыл бұрын

    thanks for the correction

  • @strattieshots

    @strattieshots

    5 жыл бұрын

    no forgiveness 😤

  • @dheerendrapandey4494

    @dheerendrapandey4494

    5 жыл бұрын

    you are too good.......I understood that mistake by see that. but you are too responsible.....I have no words to thank you!! GOd bless you!!!

  • @alwaysfreezing

    @alwaysfreezing

    5 жыл бұрын

    ok daddy

  • @munmunchakraborty5262

    @munmunchakraborty5262

    4 жыл бұрын

    I am too much pleased after hearing your lecture.Thanks sir.

  • @yasmine9046
    @yasmine90462 жыл бұрын

    This is truly amazing how complex notions can become so easy to understand when clearly explained. I’m grateful for your channel. Lots of love from France.

  • @Psiredem

    @Psiredem

    2 жыл бұрын

    Je suis aussi français et je suis totalement d'accord ! (I'm French as well and I wholeheartedly agree!)

  • @franceberat6928

    @franceberat6928

    Жыл бұрын

    Parfaitement d’accord!!! C’est dommage que l’on est pas des aussi bonnes vidéos en français , il faudrait se mettre à la page

  • @jebo2810

    @jebo2810

    6 ай бұрын

    Pareil mdrr

  • @LostInThaStereo
    @LostInThaStereo5 жыл бұрын

    You just helped me survive my O. Chem final.... now I'm discovering you cover my Genetics final too. Just... wow.

  • @poonamshah2480
    @poonamshah24802 жыл бұрын

    Thanks alot Professor Dave. Your teaching videos are not just clearing the concepts but arousing the curiosity to learn more about the topics.

  • @fajitaboys
    @fajitaboys4 жыл бұрын

    I'm literally coming here from Khan Academy--thats how high calibre you are of an educator. To be fair, the KA video I didn't like was a one-off, as generally they are pretty good. If anyone is wondering--watch this video by Prof D instead of "Regulation of transcriptions" in the KA MCAT>Biomolecules>Gene Control.

  • @yoyoyakkamon4343434
    @yoyoyakkamon43434346 жыл бұрын

    Professor Dave out here saving my A Level Biology grade amen

  • @lauragordon6414
    @lauragordon6414 Жыл бұрын

    Wow! I was not looking forward to even this 13 minute clip. But, WAS I WRONG. Your presentation is by far one of the best. Again, most of us are visual learners and the animation along with your teaching was spot on and kept me interested and rarely was I lost or confused. Thank you so very much!

  • @pablosamuelestradaochoa4127
    @pablosamuelestradaochoa41272 жыл бұрын

    You seriously CAN'T IMAGINE HOW MUCH I LOVE YOUR YT CHANEL. OMFG, SUCH A GOOD, "FRIENDLY" (easy to understand) AND YET ACADEMICLY SUFFICIENT CONTENT, WOW! Im an instant new sub, keep up the excelent work!

  • @feralscooter
    @feralscooter5 жыл бұрын

    Awesome video. Very clear and to the point. Ive been watching a lot of videos trying to wrap my head around this stuff -- this video made it stick.

  • @colloredbrothers
    @colloredbrothers5 жыл бұрын

    I was interested in diet and people used to talk a lot about insulin metabolism at first, now I'm learning about genetics and gene expression because of research I did into the keto diet and its histone deacetylase inhibiting qualities, thank God for the internet and people like you Professor! I never really liked school but I do love learning with a passion.

  • @polixaw1337

    @polixaw1337

    2 жыл бұрын

    Learning with passion is all you need!

  • @alannacronk9419
    @alannacronk94196 жыл бұрын

    bless this man and his plaid

  • @subhamdatta3521

    @subhamdatta3521

    4 жыл бұрын

    yes

  • @antwoinemorris7946
    @antwoinemorris79462 жыл бұрын

    This was very short and precise. I understand clearly all that he said more than how my professor taught it. Thank you professor 🙏🏽 🤗

  • @shreyasimhadri3863
    @shreyasimhadri38633 жыл бұрын

    YOU, prof Dave, are an AMAZING teacher. Thank you so much for your videos that I will be binging as a novice neuroscience major!!!!

  • @RedHeadSH0T
    @RedHeadSH0T2 жыл бұрын

    This is one of THE BEST biology videos on KZread!

  • @Noamm92
    @Noamm923 жыл бұрын

    hands down this is the best video on youtube of this subject man

  • @flyingbunniess
    @flyingbunniess5 жыл бұрын

    Professor Dave! I have been watching your videos for at least a year now. You got me an A- in Gen Chem 2, are currently helping me ace Organic Chem 1, and microbiology! THANK YOU. YOU ARE THE BEST

  • @najdah1991
    @najdah19913 жыл бұрын

    thank you so much professor dave, you made it in a very simple explanation!

  • @jorisvandevelden7317
    @jorisvandevelden7317 Жыл бұрын

    thanks professor Dave ! u made my nightly study session a lot more endurable

  • @happyeunjee1
    @happyeunjee16 жыл бұрын

    thank you so much~~~ This video had a lot of the details I needed to review :)

  • @mikeE997
    @mikeE9975 жыл бұрын

    Thanks for the video. Much more direct and concise than KA. Exactly what I needed for quick review on operons for the MCAT.

  • @daryljonesfoster4102

    @daryljonesfoster4102

    5 жыл бұрын

    What is MCAT ?

  • @prabh69ps
    @prabh69ps5 жыл бұрын

    Thanks and Plz give this professor a nobel prize for making this vedio ❤️

  • @karimnaraki7376
    @karimnaraki73764 жыл бұрын

    this explanation was so great thank u professor

  • @o.n.c5853
    @o.n.c58535 жыл бұрын

    i enjoy your lessons alot as they have been so so helpful..keep it up

  • @tomisakin
    @tomisakin4 жыл бұрын

    This guy and AK lectures have saved my from my profs reading slides and calling it teaching

  • @SahanTheMighty
    @SahanTheMighty3 жыл бұрын

    This is the first video I’ve watched in your channel and the opening credit had me in stitches 🤣😂🤣😂

  • @ailujotkins619
    @ailujotkins619Ай бұрын

    You explain so easily that even if i don't know english very well i can understand you AND the topic. Incredible thank you

  • @zerothehero123
    @zerothehero1235 жыл бұрын

    Just found your channel and I absolutely love it! Very in depth videos for real science geeks! Subbed and liked!

  • @vickyimery47
    @vickyimery474 жыл бұрын

    You’re an amazing teacher, thank You so much. 👌🏻🙏🏻🙌🏻

  • @biobrotherslectures793
    @biobrotherslectures7935 жыл бұрын

    A big fan of you sir !! Your video tutorials helped me a loot ❤

  • @witty_me
    @witty_me2 жыл бұрын

    Another wonderful session, thanks a ton

  • @emptypotatoskin
    @emptypotatoskin4 жыл бұрын

    Wow this cleared so much up. Thank you!

  • @sdbeauty1027
    @sdbeauty10276 ай бұрын

    Ugh so I took Gene expression this past fall and had to drop because I refuse to get a C in the course so I’m retaking it this spring. I so wish I found this video before because I honestly had no clue what was going on in the class, but this has helped me organize the concepts so much better! Thank you so much.

  • @gamingsaiyanyt6492
    @gamingsaiyanyt64924 жыл бұрын

    Sir u are brilliant and fabulous explainer of concepts .Thanks a lot May God bless you and keep making such videos. 😚😚

  • @leonwennerholm3832
    @leonwennerholm38323 жыл бұрын

    You are my secret weapon when it comes to study. :-D

  • @lehuang1924
    @lehuang19244 жыл бұрын

    Your video is so great! Thank you so much!

  • @tranghuyen4227
    @tranghuyen42276 жыл бұрын

    I love biology and chemistry

  • @user-ml6dz7hi9f
    @user-ml6dz7hi9f5 жыл бұрын

    professor Dave you are a best teacher for chemistry and biology thanks for your efforts

  • @marianasayuriudo5429
    @marianasayuriudo54293 жыл бұрын

    Thank you very much for your brilliant explanation.

  • @shinywarm6906
    @shinywarm69063 жыл бұрын

    Beautifully clear. Thanks

  • @joegabrail7175
    @joegabrail71755 жыл бұрын

    Bless ur soul professor dave

  • @TheOnlyDoctorMek
    @TheOnlyDoctorMekАй бұрын

    this is an absolutely wonderful video specifically, thank you so much. you have no idea

  • @nassimazer1608
    @nassimazer16085 жыл бұрын

    Thank you so much this video really helped!!

  • @MrRamaeri
    @MrRamaeri Жыл бұрын

    God bless you professor, thank you for your presentation.

  • @Standforthetruth18
    @Standforthetruth188 күн бұрын

    Damn, this is a piece of art. You teaching so much fun and. Simplified. Thanks a lot sir.

  • @demitriwelling1348
    @demitriwelling13482 жыл бұрын

    Excellent explanation, thanks again.

  • @tkdlover19
    @tkdlover19 Жыл бұрын

    This is super helpful, but it would be even more helpful if you put in the corner which organisms these concepts apply to, since some of these only happen in bacteria and others in eukaryotes, and still others in both. This is something that confuses me all the time, so if you make more videos along these lines in the future, that would be very informative!

  • @Zetsuke4
    @Zetsuke44 жыл бұрын

    THis is explained soo good omg

  • @angelocastro2697
    @angelocastro26975 жыл бұрын

    This is very helpful. Keep it up! You just got my sub :)

  • @MrKhya123
    @MrKhya1236 жыл бұрын

    Thank you professor. You got subscribed

  • @carlinasabella8732
    @carlinasabella87323 жыл бұрын

    this video is extremely helpful, thank u very much

  • @louisdefilippi8982
    @louisdefilippi89822 жыл бұрын

    This is an excellent review!

  • @phanindraprasadpoudel4801
    @phanindraprasadpoudel48014 ай бұрын

    Wow! wonderful teaching Prof. Dave! More than in a University.

  • @itsthatleo3970
    @itsthatleo39704 жыл бұрын

    *I love it that this video is exactly whats in Campbell*

  • @naginakhan1ify
    @naginakhan1ify5 жыл бұрын

    Very well explained!!!!

  • @manuehbadachi2961
    @manuehbadachi29616 жыл бұрын

    you're awesome! thanks

  • @EKCPUNJAB
    @EKCPUNJAB3 жыл бұрын

    Is transcription a controlling factor in enzyme production for translation or transcription itself??

  • @MyMinecrafter97
    @MyMinecrafter976 жыл бұрын

    Great video!

  • @lehlohonolokhumalo665
    @lehlohonolokhumalo6656 жыл бұрын

    Best explanation.

  • @animatetheidea7945
    @animatetheidea79456 жыл бұрын

    Nice expleined, thanks.

  • @amandarossell5167
    @amandarossell51674 жыл бұрын

    Awesome video! Only thing that it had acetylation with a methyl group and methylation with an acetyl group. Minute 9:38

  • @CaferOzdemir
    @CaferOzdemir6 жыл бұрын

    Great work as always Dave ! A small mistake: at 1:50 translation is happening in the wrong direction, it should start at 5’

  • @hakersupatytsupra9556

    @hakersupatytsupra9556

    4 жыл бұрын

    ?

  • @michellebadura8349

    @michellebadura8349

    3 жыл бұрын

    Yes, this is driving me nuts also. Translation starts from the 5' end with the methyl-G cap, then the mRNA feeds through the ribosome and finally the 3'-poly-A tail end comes out.

  • @junedaniel2981

    @junedaniel2981

    2 жыл бұрын

    But shouldn't it go in the opposite direction. Because on the "parent" strand its 3-5 but building the opposite so thats 5-3

  • @nonosaramago

    @nonosaramago

    Жыл бұрын

    RNA is single stranded 🤨

  • @cheriedvm4509
    @cheriedvm45092 жыл бұрын

    Very helpful video!

  • @puneetsingh.R.
    @puneetsingh.R.5 жыл бұрын

    Very nice video....easy to learn

  • @angibeller.gildemontes4872
    @angibeller.gildemontes48725 жыл бұрын

    Brilliant!! Thanks for this 🙏🏽🙏🏽🙏🏽

  • @subhamdatta3521

    @subhamdatta3521

    4 жыл бұрын

    yeah

  • @emilemil1871
    @emilemil18714 жыл бұрын

    I’m literally an idiot and I understood this just fine omg dont forget your hat king 👑 😌😌

  • @arnoldkatontoka8482
    @arnoldkatontoka84823 жыл бұрын

    You're a great professor, your delivering techniques with clear expressional pictures makes it easier to understand things. But also suppose you're teaching someone who's being introduced to a topic the first time, you know, not to super summarize scientific concepts.

  • @mhamidusman
    @mhamidusman5 жыл бұрын

    excellent prof

  • @aryaa7334
    @aryaa73342 жыл бұрын

    I've graduated HS and passed the need to study these (taking econ in college) but i still remain loyal to watching dave

  • @Zetsuke4
    @Zetsuke44 жыл бұрын

    More of these please

  • @christopherapuan9968
    @christopherapuan99682 жыл бұрын

    Thank you for this!

  • @kaitlynwitkowski1108
    @kaitlynwitkowski11083 жыл бұрын

    Why you explain it so much better than my textbook..

  • @aliheidarzade1375
    @aliheidarzade13756 жыл бұрын

    thanks so much..it was usefull for me

  • @bzzzvzzze
    @bzzzvzzze4 жыл бұрын

    Awesome video!

  • @DoFliesCallUsWalks
    @DoFliesCallUsWalks2 ай бұрын

    13 minutes beat 3 hours on the official AP course.

  • @sunehrikiran5638
    @sunehrikiran56386 жыл бұрын

    you're the best professor !

  • @subhamdatta3521

    @subhamdatta3521

    4 жыл бұрын

    yeah

  • @abdullahinuhuyau5173
    @abdullahinuhuyau51732 жыл бұрын

    Thanks Proff.

  • @sandhya9646
    @sandhya96462 жыл бұрын

    thanks professor dave easy to learn 😃😃😃😃😃

  • @adamastiti5825
    @adamastiti58252 жыл бұрын

    thankyou for the explanation

  • @yusinurahmah8551
    @yusinurahmah85514 жыл бұрын

    i pay my college to teach me but i always ended up on youtube because of some or so many reasons

  • @AutoMotivate
    @AutoMotivate5 жыл бұрын

    I thought the trp operon was negative and the lactose operon was postiive ?

  • @amalialatifa6248
    @amalialatifa62482 жыл бұрын

    this is help me a lot. amazing

  • @dandansong6826
    @dandansong68262 жыл бұрын

    Really perfect explanation! I have a question, so only e.coli has operator to turn gene transcription on\off, is there also operator in human?

  • @MeditacionesAlma
    @MeditacionesAlma6 жыл бұрын

    Thank you

  • @bioscienceswithshahtareenswati
    @bioscienceswithshahtareenswati2 жыл бұрын

    Amazing sir..💖❤

  • @amirkhaleghy6960
    @amirkhaleghy69603 жыл бұрын

    Thank you so much

  • @alialsaeed3322
    @alialsaeed33226 жыл бұрын

    Thanks

  • @manuelcyril4454
    @manuelcyril44546 жыл бұрын

    sorry sir i have a problem In an operon, the location of the regulatory region occurs before, within or after the structural genes.?????

  • @khunlavil3600
    @khunlavil36004 жыл бұрын

    thank for saving me

  • @Murrayt-vu3cq
    @Murrayt-vu3cq6 жыл бұрын

    nice Rembrandt lighting

  • @ismaildin69
    @ismaildin693 жыл бұрын

    Professor kindly you may help me how to identify TF of my gene sequences or TF of my genes motifs

  • @katieella7625
    @katieella76255 жыл бұрын

    You're amazing.

  • @DudeWhoSaysDeez
    @DudeWhoSaysDeez6 жыл бұрын

    there is a minor error in this video: at 9:37, you color coded the three groups, but they are not properly matched below. The methyl group should be green, and the acetyl group should be red

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    6 жыл бұрын

    ah man what a dumb error! thanks for catching that.

  • @DudeWhoSaysDeez

    @DudeWhoSaysDeez

    6 жыл бұрын

    Yeah it may be alot of work to re animate the video, but you could put an annotation with the correction

  • @ericmakakantare3523
    @ericmakakantare35232 жыл бұрын

    good one

  • @salmasyahfani817
    @salmasyahfani8173 жыл бұрын

    thank you

  • @thetop1076
    @thetop10764 жыл бұрын

    just loved it, such tough concepts explained cleanly ! bless professor Dave

  • @Ireplytoeveryislamicpig
    @Ireplytoeveryislamicpig3 жыл бұрын

    At 9:37 the func groups for acetylation and methylation are placed in wrong order please do notice

  • @kogocher
    @kogocher4 жыл бұрын

    very educational

  • @sanyasis7161
    @sanyasis71614 жыл бұрын

    Thank you very much Dave.. I would be like you one day .. professor.. ;)

  • @rainbowsandunicorns9233
    @rainbowsandunicorns92333 жыл бұрын

    Thankyou sir ✌