The Cell Cycle and its Regulation

Your cells have to divide when you're growing, to heal wounds, and to replace dead cells. But how do cells know when to divide and when not to divide? We can't have cells just growing willy-nilly! That's what cancer is, and that's bad. Luckily, cells obey something called the cell cycle, which is regulated by a variety of signaling molecules, which tell the cell when to divide and when to chill out. Let's look at the phases of this cycle and some of its regulatory mechanisms now.
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Пікірлер: 141

  • @jarednicholas3180
    @jarednicholas31806 жыл бұрын

    I am a tutor in physiology, physics, chemistry, and mathematics, and I must say you have a very special way of breaking down the information in a comprehensible, sequential manner that is just really enjoyable to hear and watch. You are definitely helping a lot of people with your linear, step-by-step methods. I've always been fond of cell signaling pathways and understanding them from start to finish. Very well organized!

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    6 жыл бұрын

    thanks very much!

  • @Zetsuke4

    @Zetsuke4

    4 жыл бұрын

    Jared Nicholas Really. what physiology do you teach? cell biology?

  • @jherlennemaeatupan7055

    @jherlennemaeatupan7055

    3 жыл бұрын

    I agree. easy to understand. Good job Professor Dave. I'm also a Science Teacher.

  • @faridsaid9180

    @faridsaid9180

    2 жыл бұрын

    @@ProfessorDaveExplainswhich type of cells? Just asking am not medical profession. Is it stem cells or lymphocytes?

  • @bernardkamau7017

    @bernardkamau7017

    2 жыл бұрын

    @@Zetsuke4 aaa

  • @nitamac1312
    @nitamac13126 жыл бұрын

    THANK YOOOOOOU. I looked everywhere for a decent video that explains this stuff! This video is clean and not a jumbled and crazy. PLEASE DONT STOP MAKING VIDEOS THEY'RE TOO GOOD!

  • @imanalkole919
    @imanalkole9195 жыл бұрын

    You need an award, sir! You are really helping me out understanding this on a basic level!

  • @mandabutangry1146
    @mandabutangry11464 жыл бұрын

    I've been struggling in class to understand the checkpoints and have had no luck in finding videos that explain how it works. I greatly appreciate your help and finally have a sense as to what is going on!

  • @aquila6668
    @aquila66683 жыл бұрын

    This is what I always want from a discussion, there are always new trivias/facts added and goes beyond the surface of the lesson (defining terms, explaining what is already in the ppt, and whatnot).

  • @angiereneewellness6227
    @angiereneewellness6227 Жыл бұрын

    Your videos are incredible and break down the most complex concepts into a step-by-step, comprehensive way. You are absolutely saving me in my biology course! Thank you!

  • @tella5357
    @tella53573 жыл бұрын

    Professor Dave is lit af man. I look at this channel for all my college classes. The way he explains is extraordinary.

  • @Shub_inc
    @Shub_inc4 жыл бұрын

    Nicely explained Dave sir! You deserve more subscribers. I hope you will get at least 10M subscribers. Love from India

  • @aramhakobyan8549
    @aramhakobyan8549 Жыл бұрын

    An excellent tutor with an excellent explaining skills. Thank you very much indeed for your tutorial videos Professor Dave!

  • @gracedemalona9197
    @gracedemalona91976 жыл бұрын

    You are fantastic! As simple as that! I can always go watch your videos, when I need 'the quick and dirty' version of a whole semester, I struggled understanding! And then so many things fall into place! Thank you Dave!

  • @samjohn2984
    @samjohn29843 ай бұрын

    Your method of teaching and breaking down concepts is absolutely remarkable. I am a chemistry teacher and my school required me to teach biology and learning from your videos has literally taught me the whole course in a few simple videos😅. Remarkable explanation. Please keep up the good work.

  • @amanyasharon5227
    @amanyasharon52276 жыл бұрын

    Well done Dave, this is a great presentation

  • @john-paulchidili2327
    @john-paulchidili2327 Жыл бұрын

    This is remarkably impressive... Prof Dave, you have a unique talent of deconstructing complex subjects. WOW!

  • @jenniferblears192
    @jenniferblears1924 жыл бұрын

    Video saved for my upcoming January exam!! Love you.

  • @AxelZaore
    @AxelZaore5 жыл бұрын

    This is indredibly great explained. Thank you so much!

  • @davidrosen5137
    @davidrosen51375 жыл бұрын

    Good tutorial as always, Dave!

  • @randomarun2950
    @randomarun29506 жыл бұрын

    This helped a little on the subject, thanks. I even learned some extra information!

  • @lukamtc9188
    @lukamtc918815 күн бұрын

    its reassuring to see that the numbers in my textbook line up perfectly with the examples you give. you are quite literally on the same page.

  • @farhanahmed2508
    @farhanahmed25086 жыл бұрын

    I am astonished by how you explained it so well. Well done...

  • @abdeljalilpr2033

    @abdeljalilpr2033

    6 жыл бұрын

    Farhan Ahmed yes i wish if it was in arabic bt this is good too

  • @CrispyApplJackz
    @CrispyApplJackz8 ай бұрын

    I LOVE THIS TYPE OF CONTENT. THANK YOU. HIGH SCHOOL ALL OVER AGAIN BUT THIS TIME I'M FOCUSED AND INTERESTED.

  • @heltiswelt
    @heltiswelt Жыл бұрын

    I really appreciate your tutorials, it helps me a lot. You deserve an award, Sir.

  • @davidkissser8011
    @davidkissser80116 жыл бұрын

    you are great, thank you Dave!

  • @JEPTEPKENY
    @JEPTEPKENY2 жыл бұрын

    Quick question- Chromosomes can be monads (a single chromatid) or dyads (sister chromatids held together by a centromere; a dyad has two identical strands of DNA held closely together in a location called the centromere). When a cell is in the G1 or Gap 1 Phase of their cell cycle, the nucleus contains monads but during the S phase the DNA is synthesized into the dyads that are seen in the G2 or Gap 2 phase. *The strands are identical assuming that no copying errors (mutations) have occurred during the S phase of the cell cycle Familiarize yourself with the conditions of a cell’s chromosomes during the G1 and G2 phases of the cell cycle. The 4 phases of mitosis: Prophase = chromosomes condense Metaphase = chromosomes line up in the middle of the cell with reference to the two poles (the equatorial plate or metaphase plate) with each chromosome on its own spindle fiber (by itself) Anaphase = separation of the chromosomes Telophase = formation of two nuclear envelopes around the two chromosomal clusters and then the cell divides (cytokinesis) Questions: In humans, there are 46 chromosomes in the nucleus of a cell. When the cells are in the G1 phase the 46 chromosomes are 46 monads which are 46 single chromatids. During the S Phase the 46 monads become 46 dyads which are 46 sister chromatids that will split during the M Phase/Mitosis. What is in the nucleus of the cell after mitosis?

  • @ThePetra136
    @ThePetra1365 жыл бұрын

    this is great video! really helped me understanding cell cycle regulation! thanks!

  • @veraojemu5105
    @veraojemu51055 жыл бұрын

    This was great. So simplified!! Thanks.

  • @rhemaray-mbata8588
    @rhemaray-mbata85883 жыл бұрын

    you are saving my life right now thank youuuu

  • @shadmehrvahedizadeh8341
    @shadmehrvahedizadeh8341 Жыл бұрын

    Very nice job Prof Dave!

  • @sserwaddaderrick1523
    @sserwaddaderrick152310 ай бұрын

    I’m a first year student of molecular biology! Thank you professor 👨‍🏫

  • @nastehaibrahim3797
    @nastehaibrahim37976 жыл бұрын

    Thank you so much for this informative video

  • @peter.biedermann1756
    @peter.biedermann17566 жыл бұрын

    Man , that was well expained. Thank you!

  • @wassoun7934
    @wassoun79345 жыл бұрын

    Amazing explanation thank you 🙂

  • @OtonashiIo
    @OtonashiIo Жыл бұрын

    Man I gotta love that iconic intro

  • @Bilbus7
    @Bilbus75 жыл бұрын

    Thank you brother Dave!

  • @risnelcopio2891
    @risnelcopio2891 Жыл бұрын

    Thank you so much for this....now clearly understood...I can now prepare my presentation☺️...God bless🙏

  • @nipunipoornima8902
    @nipunipoornima89023 жыл бұрын

    Well explained, understandable and clear... Thank you prof. All your videos are very useful. I've been watching all of them.

  • @polokocollen7072
    @polokocollen70726 жыл бұрын

    Thank you ...well explained.

  • @nalwogaphiona225
    @nalwogaphiona2253 жыл бұрын

    It's well explained. Thank u

  • @aelliyanti
    @aelliyanti2 жыл бұрын

    Thank you so much for excellent explanation

  • @AnzzCheatedOnMarkWithHaechan
    @AnzzCheatedOnMarkWithHaechan3 жыл бұрын

    This is so helpful!! Thank youu

  • @KingMB_XJ_Official
    @KingMB_XJ_Official Жыл бұрын

    In school, we watch the explanation videos. At home, I watch the debate videos.

  • @nubianzen1977
    @nubianzen19773 жыл бұрын

    @dave So Cyclins and kinases provide the signal to help the cell move along through the checkpoints...but how do they know the cells are "fit" to continue forward to the next phase.

  • @nickmachado-mejia578
    @nickmachado-mejia5782 жыл бұрын

    thank you biology jesus

  • @somasundram2975
    @somasundram29753 жыл бұрын

    Please make videos with more explanation ....request. Your videos are best .

  • @reeleltahir8479
    @reeleltahir84792 жыл бұрын

    İ wish to have you in my collage dude, i didn't just learn, i enjoyed it

  • @manjulaapm5551
    @manjulaapm55515 жыл бұрын

    Thanks . It helped me a lot.

  • @rochelroma180
    @rochelroma1803 жыл бұрын

    thank you professor dave

  • @vasilistoma7082
    @vasilistoma70829 ай бұрын

    great video really helpful thanks a lot

  • @biadiciero
    @biadiciero3 жыл бұрын

    perfect!!! sugestion: video about mosaicism

  • @Ihsannurulimansfd
    @Ihsannurulimansfd4 жыл бұрын

    one quick question dave. if nerve cells don't divide at all like you said, then how can doctors treat brain cancer? bcs, once the doctors get rid the tumor cells within the brain, don't they wait for certain amount of times so that the cells he cut form the new one. thanks

  • @ahamadaoukachioukachi7269
    @ahamadaoukachioukachi72693 жыл бұрын

    OMG THIS IS SO HELPFUL 🌺🌺🌺

  • @fluxonluck7712
    @fluxonluck77123 жыл бұрын

    Well done 👍

  • @abigailwatson3330
    @abigailwatson33302 жыл бұрын

    At this point its not my degree, its our degree! thanks for the content as always!!

  • @katerihiga2087
    @katerihiga20874 жыл бұрын

    Very clear thank you

  • @cindodo3854
    @cindodo38546 жыл бұрын

    THANK YOU SO MUCH MAN!

  • @rachel.258
    @rachel.2584 жыл бұрын

    You deserve way more subscribers

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    4 жыл бұрын

    i agree! please tell your friends :)

  • @fredpipsy3692
    @fredpipsy36923 жыл бұрын

    Thank professor dave

  • @lilacrose6828
    @lilacrose68282 жыл бұрын

    You absolutely excellent.... Lacture

  • @nyawirawaithaka4993
    @nyawirawaithaka49935 жыл бұрын

    Thank you!

  • @nu.ri22
    @nu.ri22 Жыл бұрын

    Thank you so much sir 🙏

  • @krishnabarge2837
    @krishnabarge28375 жыл бұрын

    Understood everything sir..😁

  • @Omar-Khaairy
    @Omar-Khaairy Жыл бұрын

    Thanks so much

  • @chinopopop
    @chinopopopКүн бұрын

    Thank you ❤️

  • @josefa8939
    @josefa8939 Жыл бұрын

    Your videos are great, thank you! FYI, the word "kinase" is pronounced KAI-nase.

  • @AsmaKhan-gz1by
    @AsmaKhan-gz1by3 жыл бұрын

    Thank you 😊

  • @raanimalik4007
    @raanimalik4007 Жыл бұрын

    just here to say man ur saving my butt. I love you

  • @flintey360
    @flintey3602 жыл бұрын

    Thanks King

  • @bioarh874
    @bioarh8745 жыл бұрын

    Can someone explain what the role of the Destruction-Box is ?

  • @mustaphasuso922
    @mustaphasuso922 Жыл бұрын

    You have been carrying me since high school am am in university thanks

  • @lighttecdark3504
    @lighttecdark3504Ай бұрын

    Dude you are awesome! :D

  • @pastimepursuit7212
    @pastimepursuit72122 жыл бұрын

    5:00, 5:20, 5:52, 6:40!, 6:50!, 7:22!, 7:40!, 8:35, 9:44, 10:25, 10:51!, 11:08!

  • @janakmedicos9735
    @janakmedicos97353 жыл бұрын

    Controlled cellular multiplication. And age related healing and Cancer treatment.

  • @winsorblue2428
    @winsorblue24284 жыл бұрын

    This is like watching Cr1TiKaL teach me about biology. Thanks!

  • @vailethmahenge9180
    @vailethmahenge91803 жыл бұрын

    Thanks 👍👍

  • @carolinelhouvum2251
    @carolinelhouvum22514 жыл бұрын

    Thank you thank you

  • @ilhamhasan8950
    @ilhamhasan89506 жыл бұрын

    شكرا

  • @abdeljalilpr2033
    @abdeljalilpr20336 жыл бұрын

    I was asking my self how this signal are translated ??what is this signal??elecrones ??protons?? Need more detail...any way this is a very good channel respect from morocco

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    6 жыл бұрын

    i talk about the signaling molecules in this clip! they interact with the genome to promote or inhibit gene expression. stay tuned for a future clip on regulation of gene expression.

  • @thedisintegrador

    @thedisintegrador

    6 жыл бұрын

    Usually some proteins or hormones

  • @ayakarameh6071
    @ayakarameh60714 жыл бұрын

    The Best ever

  • @hacernurertunc4529
    @hacernurertunc45295 жыл бұрын

    Even though I don't speak English, I understood the pictures.

  • @epsilonecho1436
    @epsilonecho14363 жыл бұрын

    While cells are just being cells, Prof Dave is being his usual compartmentalized messiah self :)

  • @joshtickner3339
    @joshtickner33397 ай бұрын

    Do cells grow during the g0 phase?

  • @deeblessings8547
    @deeblessings85472 жыл бұрын

    This is way better than crush-course.

  • @AlexTrusk91
    @AlexTrusk914 жыл бұрын

    0:12 looks like a big strong blue guy with red head. Noone you want to argue with trying to get into a club.

  • @Osama_Alkadomi
    @Osama_Alkadomi Жыл бұрын

    You gotta be using the campbell biology book

  • @user-mp3sm8mr1u
    @user-mp3sm8mr1u2 ай бұрын

    Best❤

  • @SrTBP
    @SrTBP5 жыл бұрын

    Wow! This is great continent! Simple and accurate! Just consider revising your explanation on chromatin structure...As far as I know chromosomes only go supercoiled for cell division...the DNA is largely in a "loose" state for replication and storage... otherwise it couldn't be used. (I'm not considering heterochromatin here, of course) Anyhow, great video!! :)

  • @thedisintegrador
    @thedisintegrador6 жыл бұрын

    Todd pls!

  • @lauramejia7103
    @lauramejia71035 жыл бұрын

    Hey Todd!! aha come on phagocyte! - haha I need to talk to people, I've been studying too long

  • @henrytai4030
    @henrytai40305 жыл бұрын

    hi taylor

  • @jenniferwang946
    @jenniferwang9463 жыл бұрын

    1:03 Why are they called daughter cells? And not son cells, for example?

  • @AnushkaSharma-ok2er

    @AnushkaSharma-ok2er

    3 жыл бұрын

    we call it daughter cell since only *female* can reproduce.. so as it will grow it will become a mother cell and divide further.

  • @henrytai4030
    @henrytai40305 жыл бұрын

    hey hey joseph

  • @rosev6052
    @rosev60522 жыл бұрын

    i think there is an error at 1:57

  • @duaa2822
    @duaa2822 Жыл бұрын

    😍😍😍✨ Thanks

  • @user-xk2oh3qp1o
    @user-xk2oh3qp1o2 ай бұрын

    i love science

  • @V_16_hmm
    @V_16_hmm3 жыл бұрын

    I just like the into

  • @shivapriya8058
    @shivapriya80586 жыл бұрын

    what is G zero phase?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    6 жыл бұрын

    it is explained in this clip, so watch again!

  • @shivapriya8058

    @shivapriya8058

    6 жыл бұрын

    what is the difference between genome and gene?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    6 жыл бұрын

    an organism's genome is all of its DNA, and within the genome there are many genes. go through some of the other content in my biology playlist for more info on this!

  • @shivapriya8058

    @shivapriya8058

    6 жыл бұрын

    Thank you sir

  • @saketkumar4972
    @saketkumar4972Ай бұрын

    Why don't we just cut that skin part where cell is dividing rapidly?

  • @simplicitas5113
    @simplicitas51133 жыл бұрын

    How is this guy a professor. He is what, 32? EDIT: Also way too good teacher for a professor, especially in Cellbiology. Psst spoiler, he is just a Bachelor.

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    3 жыл бұрын

    I'm 37, it's a KZread channel, and I'm a science communicator with a BA and MS.

  • @sturgeondtd9522
    @sturgeondtd95223 жыл бұрын

    Lmao Kin-aces got me, it is usually pronounced kyn-ace

  • @angeliquatata

    @angeliquatata

    2 ай бұрын

    Okayyyy?? You want a cookie??

  • @adarshjha5303
    @adarshjha53036 жыл бұрын

    Why nerve cells never divide?

  • @ProfessorDaveExplains

    @ProfessorDaveExplains

    6 жыл бұрын

    something about chemical signaling, they must remain in the G0 state!

  • @Osama_Alkadomi
    @Osama_Alkadomi2 жыл бұрын

    after studying biology in depth for many years I have slowly but surely started believing in a higher power. And after further research I have decided that there can only be 1 God responsible for the intricacy of the human body.

  • @WokeandProud

    @WokeandProud

    2 жыл бұрын

    As long as you don't take it too far and become a YEC then that's perfectly fine I disagree strongly because of things like emergence but it's fine of that's what you wanna believe.

  • @Osama_Alkadomi

    @Osama_Alkadomi

    2 жыл бұрын

    @@WokeandProud I do not understand what you mean by "taking it too far" secondly, things like emergence personally are not strong enough evidence to compensate for the incredible intricacy of the Universe and human physiology. However, I would not impose my beliefs on others. Although, there has to be a set of laws prohibiting homosexuality, illicit acitivities etc.

  • @e.m.5287

    @e.m.5287

    7 ай бұрын

    ​@@Osama_AlkadomiNo.