Pioneering gene therapy restores deaf toddler's hearing | BBC News

A UK toddler born deaf can now hear unaided, after a groundbreaking gene-therapy treatment.
Opal Sandy was treated shortly before her first birthday - and six months on, can hear sounds as soft as a whisper and is starting to talk, saying words such as "Mama", "Dada" and "uh-oh".
Given as an infusion into the ear, the therapy replaces faulty DNA causing her type of inherited deafness.
The trial is recruiting patients in the UK, US and Spain.
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Пікірлер: 219

  • @sharonbyrd8625
    @sharonbyrd862513 күн бұрын

    Hurray for science! So many will benefit from this. Congratulations

  • @hypercc1
    @hypercc112 күн бұрын

    Bravo. This is why science is so important. To help a deaf child hear is, frankly, amazing.

  • @Nickdeaugustine
    @Nickdeaugustine13 күн бұрын

    Science is truly miraculous!

  • @sharpshooter4063
    @sharpshooter406313 күн бұрын

    Now this is the type of media hype we need. Positive news

  • @RogerMellie-yk3gw

    @RogerMellie-yk3gw

    12 күн бұрын

    Deaf people might not agree. They're quite happy to be Deaf

  • @jacoburban2757

    @jacoburban2757

    12 күн бұрын

    ⁠@@RogerMellie-yk3gwwhile that is true deaf people still face barriers in our society and giving a child a life where she will never have to face these barriers is a accomplishment that should be celebrated

  • @RogerMellie-yk3gw

    @RogerMellie-yk3gw

    12 күн бұрын

    @@jacoburban2757 Not really. Robbing of the opportunity of being part of a proud Deaf culture and community isn't necessarily a good thing.

  • @Venator237
    @Venator23713 күн бұрын

    This is a great accomplishment! I hope this will be the first step to helping more people.

  • @Narloxs

    @Narloxs

    12 күн бұрын

    In no time at all we will have cured every disease in existence. Crazy time to be alive.

  • @Redzwan
    @Redzwan13 күн бұрын

    Congratulations UK doctors and researchers.

  • @KasirRham
    @KasirRham5 күн бұрын

    Congratulations to the doctors, scientists, and of course to Opal and her family

  • @directoraldo
    @directoraldo13 күн бұрын

    What a time to be alive 🙌🏾 I hope they're working on one that can cure depression too 😢

  • @codswallop164

    @codswallop164

    13 күн бұрын

    No thanks the last time they had to lock us down to cause depression before propagandizing us into the gene therapy.

  • @jbcentral1545

    @jbcentral1545

    13 күн бұрын

    I agree, and anxiety 😟

  • @Universalis71384

    @Universalis71384

    13 күн бұрын

    SSRI

  • @jbcentral1545

    @jbcentral1545

    12 күн бұрын

    @@Universalis71384 Been there, done that. Tablets produce a false effect, the only way to overcome the issues in one’s head is to actually address them properly. Medication does nothing to help it at worst, and maybe only mildly masks it at best. My anxiety is deep rooted and likely stems from past events in my life. Until I’ve figured out everything in my head, or my brain is somehow rewired through some groundbreaking surgery… medicine will not do anything for it.

  • @maiorproposita9957

    @maiorproposita9957

    12 күн бұрын

    Anxiety and depression have nothing to do with genes. They can be solved with psychological therapies

  • @kellyrobinson6663
    @kellyrobinson666312 күн бұрын

    This is the kinda news that makes you believe in the goodness of humanity and should be splashed across all front pages of the news. Well bloody done to the medical professionals on this amazing win. So pleased for this little girl and her family ❤

  • @jakebhenry2228
    @jakebhenry222813 күн бұрын

    Yes, SCIENCE!

  • @bobbydennis8333

    @bobbydennis8333

    13 күн бұрын

    🍸🍸

  • @jasqata3203
    @jasqata320313 күн бұрын

    Well done!!👏 the world in desperate needs for good positive news😊

  • @annab9994
    @annab999413 күн бұрын

    What an amazing progress it is! Wow!

  • @MrSidReal
    @MrSidReal12 күн бұрын

    Things are really progressing at the speed of science

  • @djjjjj
    @djjjjj13 күн бұрын

    Thats amazing

  • @ReallyJustAnotherDay
    @ReallyJustAnotherDay13 күн бұрын

    What a beautiful name for this little angel. Very happy news. Congratulations to all involved.

  • @samaafaiz6523
    @samaafaiz652313 күн бұрын

    Such mind-blowing invention I hope that all humanity able to have the benefit of it ; it will be redeem for a numberless of disorders

  • @zahidchoudhryzahidchoudhry7452
    @zahidchoudhryzahidchoudhry745213 күн бұрын

    Accolades for the team of doctors who performed this feat and best wishes for the child and family💐

  • @alumina1388
    @alumina138812 күн бұрын

    Well done to everyone who are involved in this miracle

  • @palashmatt1435
    @palashmatt143513 күн бұрын

    Outstanding massage 😮 Thank you BBC team.

  • @ShelleyM007
    @ShelleyM00711 күн бұрын

    So wonderful to see news which is pure joy, happiness (and true hope for other deaf children/ people in the future!)

  • @YarnLoverRegina
    @YarnLoverRegina13 күн бұрын

    Amazing!

  • @flashflame4952
    @flashflame495213 күн бұрын

    I've always been a real SCIENCE DORK and this is just another reason why I am happy to be one! Fantastic!!! Well done Science!!!!

  • @kimberlyperrotis8962
    @kimberlyperrotis896212 күн бұрын

    Wonderful!

  • @Natashreo
    @Natashreo11 күн бұрын

    Human DNA is like computer code. It can be edited. This is huge.

  • @stonehorsegaming
    @stonehorsegaming11 күн бұрын

    This is fantastic!

  • @Anonymous77h
    @Anonymous77h9 күн бұрын

    God bless you baby 😇

  • @JakesOnline
    @JakesOnline12 күн бұрын

    Finally, a video that explains how it works.

  • @charlesapana9935
    @charlesapana993513 күн бұрын

    Amazing

  • @lippydalips4537
    @lippydalips453712 күн бұрын

    That's Amazing!😊❤👍🏻

  • @krisfinley6706
    @krisfinley670613 күн бұрын

    This is incredible news! 👏 As someone else mentioned, I hope they'll soon develop a treatment like this for blindness as well 🙏

  • @Tini_Scrapitti
    @Tini_Scrapitti13 күн бұрын

    Awesome! One can understand the parents' fear and hesitation, as there always will be risk with new technologies and treatments, but SCIENCE ROCKS!

  • @jacoburban2757

    @jacoburban2757

    12 күн бұрын

    As a geologist major I appreciate this comment 😂😂

  • @user-yk8ei9ml3z
    @user-yk8ei9ml3z13 күн бұрын

    Awesome. Thumbs up to you scientists.

  • @MarjorieStoker-oj8fh
    @MarjorieStoker-oj8fh12 күн бұрын

    .brilliant brilliant brilliant

  • @alikanadkrk709
    @alikanadkrk70913 күн бұрын

    How may I find Doctors or Hospitals about treatment.Please help me regarding this topic because I have 2 deaf siblings.I wanna change them life.

  • @BilalMammari

    @BilalMammari

    13 күн бұрын

    Me too I try to find them

  • @fullstack5461
    @fullstack546113 күн бұрын

    That's great news!

  • @mateiteca1780
    @mateiteca178013 күн бұрын

    Great news, congrats!

  • @marianlincoln9008
    @marianlincoln900813 күн бұрын

    NOW if they can do the same thing for blindness... how Miraculous that will be. Im sure Helene Keller would Approve.

  • @teona819
    @teona81912 күн бұрын

    I hope they make it available for others too🤞

  • @arielcurra7647
    @arielcurra76475 күн бұрын

    Wonderful

  • @karlacostar4114
    @karlacostar411412 күн бұрын

    This is amazing. This could cure so many. This is just the beginning. Wow i think of all the people with genetic illnesses like cysticfibrosis , heart disease... blindness. ect How this could stop suffering

  • @lfeb
    @lfeb11 күн бұрын

    WOW!!!!

  • @farazzardariali.
    @farazzardariali.13 күн бұрын

    This is not only a science anymore add the word magic 😂❤

  • @kiringo4807
    @kiringo480713 күн бұрын

    Can it be done on elders?

  • @annab9994

    @annab9994

    13 күн бұрын

    Not yet.

  • @michaeltoma9329
    @michaeltoma932913 күн бұрын

    I’m all for it, keep progressing our technological and scientific capabilities.

  • @bobbydennis8333

    @bobbydennis8333

    13 күн бұрын

    🍸🍸

  • @besnikzogaj9887
    @besnikzogaj988713 күн бұрын

    Well done, science warriors!

  • @j7ndominica051
    @j7ndominica05113 күн бұрын

    Does it only work on babies because they are still growing? Will they undo the "cochealr implant"? Imagine having assymetric hearing with one headphone only.

  • @curiositycloset2359

    @curiositycloset2359

    13 күн бұрын

    I have that. It's fine.

  • @dixitshivam1291
    @dixitshivam129111 күн бұрын

    How much it costs? Anyone please

  • @followeroftheway8454
    @followeroftheway845412 күн бұрын

    Opal's can be unlucky but it seems it was lucky for her. 😊

  • @JASON9948
    @JASON994811 күн бұрын

    The first Post Birth Genetically Modified Human

  • @followeroftheway8454
    @followeroftheway845412 күн бұрын

    How does that replace her original DNA within the ear, unless it was via her blood, but it would have to replace her original faulty DNA gene chain?

  • @JosephineEze79
    @JosephineEze7913 күн бұрын

    Deaf ppl are gonna say this is a blow on the deaf community.

  • @annab9994

    @annab9994

    12 күн бұрын

    Don’t put your words in other’s mouth..

  • @DartmoorAR

    @DartmoorAR

    9 күн бұрын

    Some of them are definitely opposed to this. Most agree that it is the absolute right of the parents.

  • @kainaat-ummati
    @kainaat-ummati13 күн бұрын

    Can anyone please explain which gene is replay

  • @Nickdeaugustine

    @Nickdeaugustine

    13 күн бұрын

    They explained it in the video 1:24 It's the OTOF gene. Definitely worth googling.

  • @ElonHusky

    @ElonHusky

    13 күн бұрын

    onlyfans gene

  • @titteryenot4524

    @titteryenot4524

    13 күн бұрын

    Gene Simmons.

  • @curiositycloset2359

    @curiositycloset2359

    13 күн бұрын

    At least they are doing actual trials on this one, rather than rolling it out on mass, under emergency legislation.

  • @Anonymous77h
    @Anonymous77h6 күн бұрын

    When will gene therapy available in india ?

  • @phoenixreborn6065
    @phoenixreborn606512 күн бұрын

    "No real evidence of any harm or adverse effects" - Where have heard that one before? 🤔

  • @briantitchener4829

    @briantitchener4829

    12 күн бұрын

    Apparenly, they used a harmless virus to deliver the DNA. Hope it's safer than something else.

  • @RajeshKumar-tv9hn
    @RajeshKumar-tv9hn13 күн бұрын

    Wow congratulations x x. 🎉🎉🎉🎉🎉 x. I lost my hearing through mumps will it work for me omg x x. 😢😮😢🎉😮😢🎉🎉🎉🎉🎉🎉🎉🎉🎉🎉🎉❤❤

  • @jeffmeyer9319
    @jeffmeyer931912 күн бұрын

    Miraculous

  • @rebekahlittle2131
    @rebekahlittle213113 күн бұрын

  • @DW-indeed
    @DW-indeed12 күн бұрын

    Pardon?

  • @PCs454
    @PCs45410 күн бұрын

    so it only works for babies? i want to edit myself like video game customiser :(

  • @ruthsutherland2573
    @ruthsutherland257312 күн бұрын

    It'll be good to see the studies and science behind this new therapy.

  • @fionajordan6842

    @fionajordan6842

    12 күн бұрын

    You can look it up

  • @ruthsutherland2573

    @ruthsutherland2573

    11 күн бұрын

    @@fionajordan6842 were will that be please send any info

  • @bobbydennis8333
    @bobbydennis833313 күн бұрын

    2024[Gregorian] “Respect and dignity.” Furthermore:

  • @cry-rs7vv
    @cry-rs7vv8 күн бұрын

    Lets go science!

  • @coffeecrashed
    @coffeecrashed12 күн бұрын

    YEA, SCIENCE!

  • @al28854
    @al2885413 күн бұрын

    1:24 'A harmless modified virus'. So isn't how the zombie apocalypse started in the movie 'I Am Legend' ?

  • @joermnyc

    @joermnyc

    12 күн бұрын

    Modified viruses have been used for many things from these treatments to vaccines (most vaccines are inert viruses, unable to make you sick, but it’s still enough to get your immune system on the attack.)

  • @briantitchener4829

    @briantitchener4829

    12 күн бұрын

    Movies? This is the real world.

  • @sarah-kk4om
    @sarah-kk4om12 күн бұрын

    The words gene therapy are chilling. Poor baby has been genetically modified. I hope she will be ok

  • @user-nx5qg3pn5y
    @user-nx5qg3pn5y7 күн бұрын

    Therapy kya hai

  • @SherKhan-if5ew
    @SherKhan-if5ew3 күн бұрын

    Is this More Affective than Cochlear implant .

  • @AP-qj9qu
    @AP-qj9qu13 күн бұрын

    What was the cost involved in this process????

  • @MariaMartinez-researcher

    @MariaMartinez-researcher

    13 күн бұрын

    02:46. This was part of an international study.

  • @briantitchener4829

    @briantitchener4829

    12 күн бұрын

    @@MariaMartinez-researcher Nothing for the family involved. NHS.

  • @DG123z
    @DG123z13 күн бұрын

    And so it begins

  • @ramut108
    @ramut10810 күн бұрын

    When it's come to India

  • @pranititiwari6525
    @pranititiwari652513 күн бұрын

    🙏🎉👍

  • @TSOP2020
    @TSOP202013 күн бұрын

    Only a matter of time before cyberpunk 2077 is a reality and character customization will be a real thing.

  • @newforestpony9567
    @newforestpony956712 күн бұрын

    The phrase 'no proof of harm' is highly alarming and demonstrates article bias via exclusion of the full facts. There is no proof of safety because this is phase one of a clinical trial. Experimenting on children, who cannot give consent but will bear the long term consequences in to adulthood when the parents are gone, when the option of a cochlear implant exists, is ethically highly questionable. What happened to 'first do no harm'?

  • @briantitchener4829

    @briantitchener4829

    12 күн бұрын

    All scientific medical advances must by definition involve "experimentation" at some stage or no benefits would ever be seen.. I'm sure these surgeons were well aware of that. This little girl can now hear thanks to this wonderful procedure. We should be happy for her.

  • @Hearing_Health
    @Hearing_Health8 күн бұрын

    This is just the future. Birds have been able to regenerate their hearing forever. Soon hearing loss and tinnitus will be cured with a simple pill or injection.

  • @HenkyMizella
    @HenkyMizella13 күн бұрын

    😊

  • @XxTheAwokenOnexX
    @XxTheAwokenOnexX11 күн бұрын

    👍

  • @JT0007
    @JT000713 күн бұрын

    More evolved 🫡🇺🇸🇬🇧

  • @auro1986
    @auro198613 күн бұрын

    now all can listen to bbc

  • @max3eey
    @max3eey13 күн бұрын

    :)

  • @alexpeters1080
    @alexpeters108012 күн бұрын

    Baa

  • @Diarimahmoud
    @Diarimahmoud13 күн бұрын

    I'm really happy for those kinds who suffer from deaf ears and a little bit of what it is? So I appreciate u to not.

  • @elijah420stuffs2
    @elijah420stuffs27 күн бұрын

    Science does what religion can't

  • @markmartin2292
    @markmartin229213 күн бұрын

    Cure baldness next.

  • @Nxck2440

    @Nxck2440

    13 күн бұрын

    no you can live with that

  • @ayowhat6139
    @ayowhat613912 күн бұрын

    Wtf W

  • @polygonalmasonary
    @polygonalmasonary13 күн бұрын

    Another medical miracle first for Britain that American medical companies will profiteer off the back of 😞🇬🇧🌈♥️🙏

  • @dimamatat5548
    @dimamatat554813 күн бұрын

    Very good. But can we go even further, as in, making the child's hearing better than normal?

  • @annab9994

    @annab9994

    12 күн бұрын

    What for?

  • @dimamatat5548

    @dimamatat5548

    12 күн бұрын

    @@annab9994 To make him work in search and rescue, reconnaissance, etc.

  • @Tao_Tology
    @Tao_Tology13 күн бұрын

    It is important to remember that there are very many deaf people who have absolutely no interest in being "cured".

  • @Groundedsquirrel

    @Groundedsquirrel

    13 күн бұрын

    The mother describes deafness as an obstacle, which it is not. What about deaf culture and language, right?

  • @Tao_Tology

    @Tao_Tology

    13 күн бұрын

    @@Groundedsquirrel And the, implicit, attitude that someone who doesn't hear (or has limited hearing) "should" do.

  • @michaeltoma9329

    @michaeltoma9329

    13 күн бұрын

    I’m more progressive than most people, but there is no problem with “curing” deafness. Is there anything wrong with being deaf or blind? No. But I think preventing it in kids if possible is not wrong.

  • @Tao_Tology

    @Tao_Tology

    12 күн бұрын

    @@michaeltoma9329 Honey, get over yourself.

  • @annab9994

    @annab9994

    12 күн бұрын

    It’s always better to be given a choice.

  • @AA-ws2uw
    @AA-ws2uw12 күн бұрын

    This will be weaponised too 😢

  • @captainnope747
    @captainnope74713 күн бұрын

    Oh boy, the crab pot of deafness ain’t gonna like this one

  • @evanmcarthur478
    @evanmcarthur47813 күн бұрын

    Now the poor will be able to hear!

  • @curiositycloset2359
    @curiositycloset235913 күн бұрын

    Lol remember when everybody took experimental gene therapy drugs, four years ago, without any idea of the long term consequences? That was wild 😅

  • @Tao_Tology

    @Tao_Tology

    13 күн бұрын

    No, dear, since that didn't happen. Apart from your not having any idea. Because you are willfully igmorant.

  • @curiositycloset2359

    @curiositycloset2359

    13 күн бұрын

    @@Tao_Tology lol, it was untested. Still is. And you took it lol wilfully ignorant indeed.

  • @Tao_Tology

    @Tao_Tology

    13 күн бұрын

    @@curiositycloset2359 "it was un..." Nope. 'lol' you really don't want to know. You _could_ read up on the work that was done........but you don't want that. 🤣

  • @Nxck2440

    @Nxck2440

    13 күн бұрын

    You know, words like "gene therapy" actually have meanings, it's not just "any science I don't like". Gene therapy means permanently changing the DNA of one or more cells in the body for therapeutic purposes, like what was done in this video. The vaccine did not change any DNA in any cell at any time. It delivered mRNA which was turned into a protein by your own cells which was used to defend against the coronavirus.

  • @curiositycloset2359

    @curiositycloset2359

    13 күн бұрын

    @@Tao_Tology LoL vaccines usually go through 10 to 15 years of trials. When was it developed, when was it rolled out? I'm afraid you can't accept reality. But that's not my problem, it's yours.

  • @phoque121
    @phoque12113 күн бұрын

    Science 1 x 0 Religion 🤷‍♂

  • @bobbydennis8333

    @bobbydennis8333

    13 күн бұрын

    🍸🍸

  • @maryammaryam5596

    @maryammaryam5596

    12 күн бұрын

    ignorant 🤡

  • @MrMarshmelloBoi
    @MrMarshmelloBoi13 күн бұрын

    Imagine how Comrade Stephen Hawking would feel if he'd seen this if he was still alive...

  • @curiositycloset2359

    @curiositycloset2359

    13 күн бұрын

    They technically had this when he was alive. But it was experimental.

  • @billdu0342
    @billdu034213 күн бұрын

    the day where we can make cat girls is approaching

  • @curiositycloset2359

    @curiositycloset2359

    13 күн бұрын

    They already make cat bois

  • @thasannagulathasan5730
    @thasannagulathasan573013 күн бұрын

    Jesus blessing the a baby 💗💞🌷✝️🛐 Halleluja Amen 🙏

  • @Laconic-ws4bz

    @Laconic-ws4bz

    13 күн бұрын

    Thank scientists. not your wishful thinking.

  • @bobbydennis8333

    @bobbydennis8333

    13 күн бұрын

    There is no God.

  • @bobbydennis8333

    @bobbydennis8333

    13 күн бұрын

    @@Laconic-ws4bz Well said.

  • @sunnikhan4633
    @sunnikhan463312 күн бұрын

    Could this help Autism??

  • @annab9994

    @annab9994

    12 күн бұрын

    No.

  • @funkadalixx2136
    @funkadalixx213612 күн бұрын

    This is thanks to god🙏🙏🙏🎉🌈❤️❤️

  • @annab9994

    @annab9994

    12 күн бұрын

    Science. It’s called science 😉

  • @funkadalixx2136

    @funkadalixx2136

    12 күн бұрын

    @annab9994 god you mean? god created science and then sent us taylor swift to spread his message

  • @TheTardisDreamer
    @TheTardisDreamer12 күн бұрын

    This is amazing! I hope in the near future gene therapy is able to treat life-limiting genetic diseases like San Fillipo too. That would be incredible.

  • @skymanifest8339
    @skymanifest833913 күн бұрын

    Wow, the BBC actually acknowledges the existence of British people.

  • @ryangooseling
    @ryangooseling13 күн бұрын

    Amazing, but that is a bit of a moral delima

  • @annab9994

    @annab9994

    12 күн бұрын

    How so?

  • @ryangooseling

    @ryangooseling

    12 күн бұрын

    @annab9994 When does individuality become a disability. I have ADHD, my son is autistic. Personally i would not choose a therapy to cure my ADHD because it is what made me , me. My son is on the fence whether he would choose to be "normal" Making that choice for a small child for something that isnt life threatening....?

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