New drug can potentially regenerate hearing & treat hearing loss - Dr. Zheng-Yi Chen

In our latest podcast, we speak with Dr. Zheng-Yi Chen, Associate Professor at Harvard Medical School. Dr. Chen is leading the world in the field of hearing and treatments. Currently, there are no drug treatments for hearing loss. Dr. Chen and his team have now developed a potential treatment for treating hearing loss and to regenerate hearing. This can revolutionize the future of how we treat hearing loss.
Link to research: www.pnas.org/doi/10.1073/pnas...
0:00 - Introduction
1:34 - Causes of hearing loss
3:59- the impact of genes & environmental factors on hearing loss
5:56- the pathways that cause hearing loss
8:06- the impact of hair cells on hearing loss
10:55- Scope of hair cells and regeneration
15:25- steps of the study for regeneration of hair cells
17:27- compounds used for hair cell regeneration
18:21- which of these compounds are FDA approved
19:29- how the animal model was able to regenerate new hair cells using the treatment
22:06- how long did it take to see results for the animal model
23:23- link of hair cells and hearing
24:42- how to deliver the gene therapy into the ear
25:17- what was the ultimate goal of the study, and what is the next goal of the study
26:07- duration of the next phase of the study
28:25- delivery of previous gene therapies into the ear, and how it can influence the way this therapy will be delivered
29:27- how will success be measured and how can it be used in a clinical scenario
33:50- what needs to be seen in the next phase of the study to be successful
35:40- how soon can this potential treatment be available
37:30- will this therapy be a one time treatment or multiple time treatment
39:05- important findings; how hearing loss can be linked to other diseases like dementia
41:41- how are other gene therapies for hearing being administered
42:52- timeline of clinical trials for genetic hearing loss
45:27- Conclusion
#hearing #hearingloss #hearinglosstreatment #clinicaltrials #harvard #dementia #genetherapy #regenerativemedicine #doctor #medicine #clinicaltrials

Пікірлер: 73

  • @MariaCrowe-hx5yx
    @MariaCrowe-hx5yx2 ай бұрын

    I wish there was a way to find donations for this research to move it along faster. Does anyone have any ideas?

  • @RieserMan
    @RieserMan8 ай бұрын

    The FX-322 from Frequency Therapeutics was failing the long term tests at hospitals. Unfortunately they gave up researching. Hopefully Dr. Zheng is continuing his own development with success.

  • @prabesholi4118
    @prabesholi411811 ай бұрын

    I was so frustrated due to tinnitus and came here to know the update of hearing loss cure. I hope Dr. Zheng and team may success in regeneration of hearing cells within end of this year.

  • @Joe-rd3bg

    @Joe-rd3bg

    5 ай бұрын

    Me too I need so much help that I am sad every day

  • @user-gl9bw5wq5d

    @user-gl9bw5wq5d

    4 ай бұрын

    End of this year in the Dream maybe

  • @Rakesh4809
    @Rakesh48099 ай бұрын

    Light of hope for the millions.

  • @technicalrider6196

    @technicalrider6196

    4 ай бұрын

    Multi millions and hope its affordable for all

  • @pimentocheese618

    @pimentocheese618

    16 күн бұрын

    @@technicalrider6196I wouldn't be so sure of it :( it requires millions and millions of dollars to mantain this kind of researching. If there's a cure available to all the world, probably will be very expensive. But hey, if this is something that will cure our hearing or tinnitus, I'd pay whatever it costs

  • @autismspeakz

    @autismspeakz

    7 күн бұрын

    Billions must hear

  • @nitroelectric5170
    @nitroelectric51707 ай бұрын

    I really hope this is a success for everyone who is struggling.

  • @tanvirmultani1330
    @tanvirmultani133010 ай бұрын

    I am looking for hearing loss cure since year this so far best information I found appreciate this thanks alot

  • @kazimsenoglu5269
    @kazimsenoglu52698 ай бұрын

    Dr. Zheng Yi Chen, First off bless your heart. My mom has a moderate to severe hearing lost. İt has been very challanging to our entire family. We tried multiple hearing devices with variying amount amount of sucess and failure. The issues varies from device to device and differnt types of issues technical, quality, usability, accessibility, continuing support. This recording really gave me hope. I thank you again such illuminating session. I also thank the host to bring this to the public. I sure appreciate this a great deal.

  • @westfield90
    @westfield905 ай бұрын

    Please let this work out. We really need major breakthroughs in medicine, heart disease, cancer, hearing.

  • @ts4gv
    @ts4gv7 ай бұрын

    Would be nice to get this treatment once a year if reasonably priced-like a tuneup for your ears

  • @tonyquinlan7341
    @tonyquinlan73413 ай бұрын

    This sounds very positive, respect to the interviewer for not interrupting DR-Zheng, hopefully we will get updated in the near future.

  • @afina6822
    @afina6822 Жыл бұрын

    Amazing news, I can't believe this channel doesn't have more views this is life changing!

  • @regenmedglobal

    @regenmedglobal

    Жыл бұрын

    Thank you, Afina! Please follow & share! We hope to continue connecting people with the newest breakthroughs in treatments.

  • @udaysaha2762

    @udaysaha2762

    3 ай бұрын

    World curiously waiting for the drug availability as the only hope at the earliest. Great news,looking forward....

  • @AnkitJain-lr1se
    @AnkitJain-lr1se10 ай бұрын

    Hope you will give us a good news soon

  • @irened9867
    @irened98678 ай бұрын

    Thank you for your work with this frustrating disease process. This December will be a year of suffering from tinnitus. Some days are so hard. I pray I will be free of this horrible noise one day.

  • @Joe-rd3bg

    @Joe-rd3bg

    5 ай бұрын

    I hear you I am in the same position what can we do

  • @nickreynolds575
    @nickreynolds5758 ай бұрын

    Hope to see good news soon 🙏

  • @naelbeno6249
    @naelbeno62492 ай бұрын

    From the Bottom of my Heart please Help us!😖😫❤️

  • @andrew8972
    @andrew897210 ай бұрын

    Hopefully this cures tinnitus and hyperacusis 🙏🏽

  • @DonAdnan123

    @DonAdnan123

    7 ай бұрын

    If it does work, which I think it will. It I’ll cure just about everything. Hearing related

  • @user-gl9bw5wq5d

    @user-gl9bw5wq5d

    4 ай бұрын

    ❤️🙏🏼 Please God help us !

  • @kathyc9354
    @kathyc93544 ай бұрын

    Is it possible to do another interview with Dr. Zheng-Yi Chen in 2024 to see if any progress has been made?

  • @vegetossgss1114

    @vegetossgss1114

    Ай бұрын

    yes!

  • @pimentocheese618

    @pimentocheese618

    16 күн бұрын

    @@vegetossgss1114how u know mate

  • @mdavis05
    @mdavis058 ай бұрын

    I really hope so, been let down every other time someone proposed this.

  • @callummackay1031
    @callummackay10312 ай бұрын

    Viva Dr Zheng.

  • @sammyeow
    @sammyeowАй бұрын

    My fathers hearing was lost after he had a surgery and was given a high dosage of antibiotics. I researched and found this is what caused the loss of stereocillia in the ear. It's been three years since his surgery, he is growing depressed and I can't communicate with him like we used to. We can't listen to music, he can't participate in conversations at dinner. He also developed early stage dementia and cannot learn ASL. Please Dr. never give up on your research.

  • @Ryliftz

    @Ryliftz

    8 күн бұрын

    I’m so sorry Sammy.

  • @Ryliftz

    @Ryliftz

    8 күн бұрын

    God bless

  • @MariaCrowe-hx5yx
    @MariaCrowe-hx5yx2 ай бұрын

    Can Regenmed global give us an updated interview with Dr. Chen?

  • @user-pu9vk5dr3s
    @user-pu9vk5dr3s8 ай бұрын

    Pray Dr Zheng will be successful in his research. I have hearing loss. Actually TCM Acupunture has helped me before. Acupunture in Singapore. Believe there is a blockage in Eustachian tube.

  • @cleanqueen75
    @cleanqueen754 ай бұрын

    My husband lost his hearing in one ear from a high fever when he had the mumps. He was 10 years old. He was told there’s nothing that can be done. He also has bad tinnitus in both ears.

  • @user-gl9bw5wq5d
    @user-gl9bw5wq5d4 ай бұрын

    PLEASE GOD HELP US! ❤️😢🥺

  • @vegetossgss1114
    @vegetossgss1114Ай бұрын

    that's amazing! and please doctor cure tinnitus!

  • @luisselby7041
    @luisselby704111 ай бұрын

    Good news for me ,

  • @namefamily1462
    @namefamily1462Ай бұрын

    hope for me

  • @miketheman6243
    @miketheman62438 ай бұрын

    What about SCDS, a thinning of the semi circular canal ?

  • @CynthiaArmstrong7
    @CynthiaArmstrong79 ай бұрын

    How are the hair cells in the elderly in the Blue Zones? Do their centenarians still have their hearing?

  • @rovioronald6612
    @rovioronald66127 ай бұрын

    🎉great👍👏😊

  • @KphyyPolure
    @KphyyPolure Жыл бұрын

    بالتوفيق انشاء الله

  • @-iIIiiiiiIiiiiIIIiiIi-
    @-iIIiiiiiIiiiiIIIiiIi-9 күн бұрын

    So thankful for the children of the Dragon.

  • @greg1030
    @greg1030Ай бұрын

    Can I really dare to believe that within three years I can get my deepest love for living back?

  • @MariaCrowe-hx5yx

    @MariaCrowe-hx5yx

    Ай бұрын

    me too!!

  • @MiguelAngel-fp9rr
    @MiguelAngel-fp9rr Жыл бұрын

    Apúrense por favor……….

  • @joshabraham7760
    @joshabraham77605 күн бұрын

    So if successful will the hair cells be as strong as they once was ?

  • @mohanraavi-hj6lm
    @mohanraavi-hj6lm8 ай бұрын

    Sir you are my God, please give me solution for sensorial hearing loss cure please sir.

  • @ahamednabi5078

    @ahamednabi5078

    7 ай бұрын

    There is only one God Almighty ALLAH, please come back and worship him. May Allah help the doctor in his initiative. Amin.

  • @lameaneko9492

    @lameaneko9492

    3 ай бұрын

    There is no other God than the only one that created us, it would be better if you pray him to make them succeed.

  • @Aviorrok
    @Aviorrok7 ай бұрын

    So 2030s decade will be breakthrough in hearing loss treatments

  • @DonAdnan123

    @DonAdnan123

    7 ай бұрын

    I think even before

  • @pimentocheese618

    @pimentocheese618

    16 күн бұрын

    @@DonAdnan123I hope god hears you

  • @joshuddin7149
    @joshuddin71495 ай бұрын

    when will the cure be available for the patient who lost sudden sensorineural hearing? someone should post the update.

  • @mujammilsindhi1152
    @mujammilsindhi115220 күн бұрын

    Its work in Congenital hearig loss or not?

  • @mori3704

    @mori3704

    7 күн бұрын

    That's for people that had hair cells when theye were born but damaged them with noise, infection... But there was a succesful trial for genetic hearing loss recently, the otof gene therapy.

  • @mujammilsindhi1152

    @mujammilsindhi1152

    7 күн бұрын

    Sir my daughter have severe to profound hearing loss can you help me

  • @mujammilsindhi1152

    @mujammilsindhi1152

    7 күн бұрын

    Her age 21 months

  • @technicalrider6196
    @technicalrider61964 ай бұрын

    Jaldi lao 😢

  • @Hew.Jarsol
    @Hew.Jarsol11 ай бұрын

    Evidently the human body isn't as clever as it thinks it is

  • @IdastreatStreat
    @IdastreatStreat8 ай бұрын

    Is this new drug for hearing loss already out? Or how soon is it expected to be available to the public?

  • @MRPHILLIESFAN24

    @MRPHILLIESFAN24

    6 ай бұрын

    Not available yet and probably not for several years.

  • @MiratCulinaryJourney
    @MiratCulinaryJourney4 ай бұрын

    Привет из Казахстана ❤

  • @andycarrillo48
    @andycarrillo483 ай бұрын

    Breh how can people be more educated and maybe even help the doctors to find the cure fur the ear issues

  • @karwanduski8307
    @karwanduski83074 ай бұрын

    🥲🥲🥲🥲

  • @peterkovacs9086
    @peterkovacs90864 ай бұрын

    Today is 2024.01.25. Any result now?

  • @lameaneko9492

    @lameaneko9492

    3 ай бұрын

    Yeah, I'm wondering too

  • @tonyquinlan7341

    @tonyquinlan7341

    3 ай бұрын

    Me too

  • @hanantot8831
    @hanantot88312 ай бұрын

    It's close to miracle for me, i had a kind of accident in my left ear. I'm from India , I'd like to volunteer if it works... I'll provide my email or number,,if atleast someone is interested