New drug can potentially regenerate hearing & treat hearing loss - Dr. Zheng-Yi Chen
In our latest podcast, we speak with Dr. Zheng-Yi Chen, Associate Professor at Harvard Medical School. Dr. Chen is leading the world in the field of hearing and treatments. Currently, there are no drug treatments for hearing loss. Dr. Chen and his team have now developed a potential treatment for treating hearing loss and to regenerate hearing. This can revolutionize the future of how we treat hearing loss.
Link to research: www.pnas.org/doi/10.1073/pnas...
0:00 - Introduction
1:34 - Causes of hearing loss
3:59- the impact of genes & environmental factors on hearing loss
5:56- the pathways that cause hearing loss
8:06- the impact of hair cells on hearing loss
10:55- Scope of hair cells and regeneration
15:25- steps of the study for regeneration of hair cells
17:27- compounds used for hair cell regeneration
18:21- which of these compounds are FDA approved
19:29- how the animal model was able to regenerate new hair cells using the treatment
22:06- how long did it take to see results for the animal model
23:23- link of hair cells and hearing
24:42- how to deliver the gene therapy into the ear
25:17- what was the ultimate goal of the study, and what is the next goal of the study
26:07- duration of the next phase of the study
28:25- delivery of previous gene therapies into the ear, and how it can influence the way this therapy will be delivered
29:27- how will success be measured and how can it be used in a clinical scenario
33:50- what needs to be seen in the next phase of the study to be successful
35:40- how soon can this potential treatment be available
37:30- will this therapy be a one time treatment or multiple time treatment
39:05- important findings; how hearing loss can be linked to other diseases like dementia
41:41- how are other gene therapies for hearing being administered
42:52- timeline of clinical trials for genetic hearing loss
45:27- Conclusion
#hearing #hearingloss #hearinglosstreatment #clinicaltrials #harvard #dementia #genetherapy #regenerativemedicine #doctor #medicine #clinicaltrials
Пікірлер: 73
I wish there was a way to find donations for this research to move it along faster. Does anyone have any ideas?
The FX-322 from Frequency Therapeutics was failing the long term tests at hospitals. Unfortunately they gave up researching. Hopefully Dr. Zheng is continuing his own development with success.
I was so frustrated due to tinnitus and came here to know the update of hearing loss cure. I hope Dr. Zheng and team may success in regeneration of hearing cells within end of this year.
@Joe-rd3bg
5 ай бұрын
Me too I need so much help that I am sad every day
@user-gl9bw5wq5d
4 ай бұрын
End of this year in the Dream maybe
Light of hope for the millions.
@technicalrider6196
4 ай бұрын
Multi millions and hope its affordable for all
@pimentocheese618
16 күн бұрын
@@technicalrider6196I wouldn't be so sure of it :( it requires millions and millions of dollars to mantain this kind of researching. If there's a cure available to all the world, probably will be very expensive. But hey, if this is something that will cure our hearing or tinnitus, I'd pay whatever it costs
@autismspeakz
7 күн бұрын
Billions must hear
I really hope this is a success for everyone who is struggling.
I am looking for hearing loss cure since year this so far best information I found appreciate this thanks alot
Dr. Zheng Yi Chen, First off bless your heart. My mom has a moderate to severe hearing lost. İt has been very challanging to our entire family. We tried multiple hearing devices with variying amount amount of sucess and failure. The issues varies from device to device and differnt types of issues technical, quality, usability, accessibility, continuing support. This recording really gave me hope. I thank you again such illuminating session. I also thank the host to bring this to the public. I sure appreciate this a great deal.
Please let this work out. We really need major breakthroughs in medicine, heart disease, cancer, hearing.
Would be nice to get this treatment once a year if reasonably priced-like a tuneup for your ears
This sounds very positive, respect to the interviewer for not interrupting DR-Zheng, hopefully we will get updated in the near future.
Amazing news, I can't believe this channel doesn't have more views this is life changing!
@regenmedglobal
Жыл бұрын
Thank you, Afina! Please follow & share! We hope to continue connecting people with the newest breakthroughs in treatments.
@udaysaha2762
3 ай бұрын
World curiously waiting for the drug availability as the only hope at the earliest. Great news,looking forward....
Hope you will give us a good news soon
Thank you for your work with this frustrating disease process. This December will be a year of suffering from tinnitus. Some days are so hard. I pray I will be free of this horrible noise one day.
@Joe-rd3bg
5 ай бұрын
I hear you I am in the same position what can we do
Hope to see good news soon 🙏
From the Bottom of my Heart please Help us!😖😫❤️
Hopefully this cures tinnitus and hyperacusis 🙏🏽
@DonAdnan123
7 ай бұрын
If it does work, which I think it will. It I’ll cure just about everything. Hearing related
@user-gl9bw5wq5d
4 ай бұрын
❤️🙏🏼 Please God help us !
Is it possible to do another interview with Dr. Zheng-Yi Chen in 2024 to see if any progress has been made?
@vegetossgss1114
Ай бұрын
yes!
@pimentocheese618
16 күн бұрын
@@vegetossgss1114how u know mate
I really hope so, been let down every other time someone proposed this.
Viva Dr Zheng.
My fathers hearing was lost after he had a surgery and was given a high dosage of antibiotics. I researched and found this is what caused the loss of stereocillia in the ear. It's been three years since his surgery, he is growing depressed and I can't communicate with him like we used to. We can't listen to music, he can't participate in conversations at dinner. He also developed early stage dementia and cannot learn ASL. Please Dr. never give up on your research.
@Ryliftz
8 күн бұрын
I’m so sorry Sammy.
@Ryliftz
8 күн бұрын
God bless
Can Regenmed global give us an updated interview with Dr. Chen?
Pray Dr Zheng will be successful in his research. I have hearing loss. Actually TCM Acupunture has helped me before. Acupunture in Singapore. Believe there is a blockage in Eustachian tube.
My husband lost his hearing in one ear from a high fever when he had the mumps. He was 10 years old. He was told there’s nothing that can be done. He also has bad tinnitus in both ears.
PLEASE GOD HELP US! ❤️😢🥺
that's amazing! and please doctor cure tinnitus!
Good news for me ,
hope for me
What about SCDS, a thinning of the semi circular canal ?
How are the hair cells in the elderly in the Blue Zones? Do their centenarians still have their hearing?
🎉great👍👏😊
بالتوفيق انشاء الله
So thankful for the children of the Dragon.
Can I really dare to believe that within three years I can get my deepest love for living back?
@MariaCrowe-hx5yx
Ай бұрын
me too!!
Apúrense por favor……….
So if successful will the hair cells be as strong as they once was ?
Sir you are my God, please give me solution for sensorial hearing loss cure please sir.
@ahamednabi5078
7 ай бұрын
There is only one God Almighty ALLAH, please come back and worship him. May Allah help the doctor in his initiative. Amin.
@lameaneko9492
3 ай бұрын
There is no other God than the only one that created us, it would be better if you pray him to make them succeed.
So 2030s decade will be breakthrough in hearing loss treatments
@DonAdnan123
7 ай бұрын
I think even before
@pimentocheese618
16 күн бұрын
@@DonAdnan123I hope god hears you
when will the cure be available for the patient who lost sudden sensorineural hearing? someone should post the update.
Its work in Congenital hearig loss or not?
@mori3704
7 күн бұрын
That's for people that had hair cells when theye were born but damaged them with noise, infection... But there was a succesful trial for genetic hearing loss recently, the otof gene therapy.
@mujammilsindhi1152
7 күн бұрын
Sir my daughter have severe to profound hearing loss can you help me
@mujammilsindhi1152
7 күн бұрын
Her age 21 months
Jaldi lao 😢
Evidently the human body isn't as clever as it thinks it is
Is this new drug for hearing loss already out? Or how soon is it expected to be available to the public?
@MRPHILLIESFAN24
6 ай бұрын
Not available yet and probably not for several years.
Привет из Казахстана ❤
Breh how can people be more educated and maybe even help the doctors to find the cure fur the ear issues
🥲🥲🥲🥲
Today is 2024.01.25. Any result now?
@lameaneko9492
3 ай бұрын
Yeah, I'm wondering too
@tonyquinlan7341
3 ай бұрын
Me too
It's close to miracle for me, i had a kind of accident in my left ear. I'm from India , I'd like to volunteer if it works... I'll provide my email or number,,if atleast someone is interested