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@Menthix

2 ай бұрын

Great video, and a very interesting topic. Sarms and peptides really need more research and should come to the front lines of healthcare.

@demetriuscooksey7147

2 ай бұрын

Can you tell us how much it costs, and if it's covered by insurance?

@yaboycookz

Ай бұрын

So where can I get these peptides? I'm not seeing them anywhere.

@lasombor1

Ай бұрын

This is soooo nothing saying that even my president can't do better. Zero zero zero...

I am currently taking BPC 157 and TB500. needed a left shoulder reconstruction hadn’t gotten more than 2 hours of sleep a night for 2 years. couldn’t put a shirt on without agonizing pain. 2 weeks later, no pain i can press 80lbs for shoulder press at 165lbs body weight. Zero side effects. It brought me out of my depression from not being able to do anything and the increased sleep made my testosterone jump 134 points. (i’m 24) I swear by this.

@georgegeorgio70

Ай бұрын

What company did you take? Thats amazing to hear

@yungemu3236

Ай бұрын

Link to the site bro

@jasonp621

Ай бұрын

@@georgegeorgio70 prescribed by a dr didn’t buy from a site.

@jasonp621

Ай бұрын

@@yungemu3236 prescribed by a dr didn’t buy from a site.

@robspencer9320

Ай бұрын

What's your dosage for each ? I am starting this weekend for a knee injury. Any info is appreciated

Finally an athlete thats transparent and honest.nice to see 💪

@dappas8682

2 ай бұрын

If he’s being transparent he should address the heavy steroid use in strongman…no one else has the balls to do it…

@distraught69

2 ай бұрын

And he's not a pioneer and at this point he's jumping on the bandwagon

@getchapull3541

2 ай бұрын

​@@dappas8682there's a lot on the line if they do that. Sponsorship being one.

@luizmertenscavaillier

2 ай бұрын

​@@dappas8682He explained why he won't do that in the beginning of the series.

@gamertd4093

2 ай бұрын

@@dappas8682heavy steroid use usually means death at a young age. Most strongmen are living well into their 60s and 70s. The difference here is what steroids are being used vs bodybuilders. Also who gives a fuck if they use steroids? I don’t get why people like you are so butthurt about it

Seriously Mitchell, you had a great idea with this serie. It's really nice to have your view on the subject and thanks for your transparency.

@mitchellhooperstrongman

2 ай бұрын

Thank you!

@goofygrandlouis6296

2 ай бұрын

No Stone Unturned Ep. 8 - Steroid cycles

Can wait for the episode on Steroid cycles

@true-fiction

2 ай бұрын

I think he said in the supplement episode that he's not going to talk about that.

@Kansanite

2 ай бұрын

Nope, that's a learn on your own topic 😂

@gsftbeast9761

2 ай бұрын

Whatever he’s says just times it by 5 these strongman competitor are no on low dosages

@alexlorincz9912

2 ай бұрын

Maybe when he retires he’ll talk about it

@So-FarGone

2 ай бұрын

@@true-fiction shame, he seemed like the first transparent bodybuild. that's sad but understandable.

mitchell is so honest, its super refreshing. amazing content and the edits are so good. really felt like a big documentary you would see from a studio

One of the best sports/health videos I've watched. Thanks for talking about real stuff

Love all your videos but I especially love this series right now and am looking forward to it every week!

I was hoping you would cover this, mitch. Cheers

Brilliant to see you finally cutting a strong path forward in trying too be as open as you can with your personal life as a top level athlete and on this interesting topic people dont know its a very small parts of the the hole picture.

Your communication and transparency is amazing

This is pure gold, thank you very much 👊

Thanks for the coverage on this type of topic

Man this is just confirmation for me. Been struggling lately something feels off reached out to a health and wellness dr had all my blood work done last week and now I go in 2 weeks to see where all my levels are at. This series has been awesome keep it up!

Love this video and your peptide journey, well done and honest, I will be following! Thanks

I’m loving the series ! Don’t know how your videos don’t get more views , people are missing out. Keep it going !

@jeffreypetree7163

27 күн бұрын

I personally just stumbled on this video today . So I'm subscribing.

you know theese strongman guys are all great...but Mitch is different. He is so smart and greedy for knowledge. so nice to have him! looking forward for the next episode. peace!

I'm 3 weeks into BPC157 and TB500 and the impact they've had on an issue I've been having with my knee have been phenomenal. Beforehand I was unable to even bodyweight squat following an injury sustained in the run up to a competition, and just yesterday I was able to box squat 60kg. This is huge for me after the last 12 months or so. Fingers crossed rehab and recovery continue this well, and hopefully there are no unforeseen issues with these compounds that come to light in future 😅 Thanks for this video, Mitch, echoing much of what I've already been hearing but great to see it coming from someone like yourself.

@mightylordkuba

2 ай бұрын

:D wait till you go off... This stuff more mask the pain rather than heal itselves. But if you do not train hard and give your body recovery it will heal itselves despite peptide use.

@Dogmaaction

2 ай бұрын

How did you get prescribed/get ahold of BPC 157? I was under the impression it was banned? Thanks in advance

@syclone1012

2 ай бұрын

@@Dogmaaction Transcend offers it.

@ASOA_STRENGTH

2 ай бұрын

@@Dogmaaction I'm in the UK so at the moment it's still very easy to buy as a research drug not for human consumption.

@ASOA_STRENGTH

2 ай бұрын

Further - I managed 170kg x 2 on my box squats last week at the peak of a huge pyramid set. It's definitely working for me 😁

Great video. Thanks Mitchell!

You're great, thanks for making these! 🙏

I have so much respect for you talking so openly about it. I don´t do peptides and never will, but thanks for the transparency☝

BPC 157 helped me with my hip problem. It is pretty amazing stuff.

@randallgd

2 ай бұрын

Curious how it helped if you don't mind? Got a hip issue myself

@fakename5015

2 ай бұрын

Shoulder here. I have no control experiment but my doc felt I healed fast and he’s done over 5,000 shoulders…got it from my doc who uses a compounding pharmacy

@jayargo1460

2 ай бұрын

Where did you end up getting your BPC157?

@fakename5015

2 ай бұрын

@@jayargo1460 doc

@655deadlift

2 ай бұрын

@@jayargo1460 from England.

This is so important. I've had TRT for a decade and tried peptides on and off to great benefit in all cases every time. Better health and optimising life.

@JRRod-yc8em

Ай бұрын

Which peptides?

@olivergilmartin

Ай бұрын

@@JRRod-yc8em CJC 1295 and Epomaralin.

You are amazing. Thank you for existing

This was such a cool video man. Thanks for this.

@mitchellhooperstrongman

2 ай бұрын

No problem! LHBK

@benmrgamw681

Ай бұрын

​@@mitchellhooperstrongmancan i ask if you would work out while taking bpc 157? Ive had issues on the outside of my elbows while gripping and upright rows etc for a long while now

This s a great series MItch, would be good if you can find a way to extend the mini series into a regular feature. Informative detailed unbiased, delves into subjects based on science and evidence. keep up the good work and good luck with the WSM prep

@mitchellhooperstrongman

2 ай бұрын

I definitely have plans to include this style moving forward!

This man is 1 of a kind...love ya

This was a really good video and well edited too, nice one mate.

Good to finally see a video that informs honestly about these issues. Every other video I see is just a natty or not cancel culture parade and they create such an unhealthy environment online or in reality. Thanks Moose! #LHBK

Great video and a great very detailed description of these peptides! Cheers for the Content

@mitchellhooperstrongman

2 ай бұрын

Thank you!

@valerie.mccaffrey

7 күн бұрын

mirin the muscle separation

Excellent video from a superior channel.

This was a great episode and really enjoyed your breakdown of this topic

Awesome vid Mitchell. Love your honesty and you videos are so informative! So I looked into doing a course of bpc157 & tb500 (tb4) quite some time ago after an injury. I tried to consult a doctor beforehand. Not only had no doctor I spoke to even heard of peptides, no physio no trainer no one had even heard of the compounds or any peptide. Maybe the uk is a little behind but it was very difficult to get medical advice.

@robertwilliams5618

Ай бұрын

Drs don't know shit

@keithrobinson357

Ай бұрын

Me too

really appreciate Mitch for putting this forward, greg's tried to do his best but sometimes folks of high level even need help, total respect (btw mitch noticed your sub counter growing fast.... congrat's, you'll hit that 200K mark within 2-3 months i think, keep going, Keltie O'conner, probably the most BA female fitness person on YT thought she'd never hit 60K and now she has over 600K.... yhou can do this friend, also if your looking for a collab she'd probably be down, your both Canadian afterall lol)

@Lucas_Jeffrey

2 ай бұрын

No one expects strongmen to be 'natural'. It's a very unnatural endeavor. No one is going to live forever, everyone should be free to use their body as they wish. Ofc it makes sense to discourage steroids, but I wonder what good is being done by banning injured athletes from using BPC157 to recover to baseline. It's not even in the same ballpark as anabolic steroids or even hGH.

Love the series

Thanks for the good content. It’s appreciated. 👍👌

oh, looks like Mitchell is brave, uploading this. strong!

@three6gaming195

2 ай бұрын

what do you mean? its not like people don't know they take stuff if you are at that top of the game you pretty much have to

@warlordmel

2 ай бұрын

​@@three6gaming195Excuse me?? 😅😅 NO ONE talk about their usage... Name one ACTIVE Strongman with vids talking about usage... This IS BRAVE as hell and interesting... + if any other Active strongman doesn't take what he does, guess what they will do the day after tomorrow or sooner...

@sariusslain

2 ай бұрын

always more respect for someone, how is being open about it, instead of just not denying@@three6gaming195

@IVIFII2IC

2 ай бұрын

@@three6gaming195there’s a lot of stupid people brother 😂

@tyronenosworthy1874

2 ай бұрын

Its not illegal numb nuts lol. You can literally buy it in Canada online

I’m a peptide user, and I can attest to the greatness of these substances. If used responsibly. I truly enjoyed GHRP-6 and BPC-157. They helped me heal my ulcerative colitis, heal my injuries, and gain ten lean pounds of muscle.

@warlordmel

2 ай бұрын

Do you know if women also can take for healing... My mom injured her shoulder and get poor help from hospital.. Even though we live in Sweden with good healthcare.. She also is on the older side, 73, but active.. Ty for answer 🙏

@user-yq3wi6gb9n

2 ай бұрын

@@warlordmel bro, I’ve put so many injured old folks on it, I can’t recommend BPC-157 enough for men and women.

@warlordmel

2 ай бұрын

@user-yq3wi6gb9n So even safe for my most precious thing in the world, my kids excluded, Mom ❤ Very interesting... Any way i can reach out to you for more info? Cheers from Sweden!

@warlordmel

2 ай бұрын

@user-yq3wi6gb9n Man sounds Awesome!! Any way I can reach out for more info, PM in any way or such? 🤔

@DadGetsFit

2 ай бұрын

Is this something you would take to help recovery? I train heavy but suffer on recovery

Man this series has been informative!!

Awesome video. Really well done.

Grateful for this. Never considered peptides or anything like them, but I’ve always been curious how people reach peak performance.

@mitchellhooperstrongman

2 ай бұрын

Thank you! If you're interested, head to blokes.co to learn more

I don’t understand how the series is called “no stone left unturned” but refused to talk about steroids. There’s a stone left unturned

@jasoncrandall

Ай бұрын

Peptides aren’t Steroids.

@stewdude1857

Ай бұрын

being the stone he lifts are 300pd plus. you fkn ask him peewee.

@audiofreak09

Ай бұрын

This vid is about peptides dummy

@audiofreak09

Ай бұрын

This vid is about peptides dummy

That intro was fire, the content is clearly getting better!

Hi Mitchell loving your content it’s extremely informative and honest. I’m reaching out to you because somethings is happening to me which isn’t spoken about in the fitness/strength industry at all and I feel that in another 10-15 years it’s going to become a big killer of under 40. Long story short, been training since the age of 20 years old, all kinds of training and when I was 24-25 years old decided to go onto steroids, not particularly a high dose initially but gradually over time I took just about everything competed in a few local strongman competitions etc and pretty much was on steroids virtually all the time so 14-15 years. I was a doorman for years so it just went with the territory I guess. When I was 39 just by chance I was having a scan on my heart for something unrelated and by chance they found an aortic root aneurysm that was 51mm. I immediately changed my lifestyle, stopped taking steroids went cold turkey and stopped lifting heavy weights, I did have to go on trt as I’ve destroyed my natural testosterone production. Fast forward 7 years as with regular scans I am now facing major open heart surgery within the next 6 weeks to replace my aortic root, if I don’t have it done it will eventually kill me. I want to raise awareness simply because the amount of young men on steroids now and the ridiculous dosages they are on, it’s going to kill a lot of men going forward and virtually no one is aware of what aortic aneurysms are. When i mention it to lads in the gym they don’t know what an aortic aneurysm is.Whether it’s an interview or if you just do a piece about it, i genuinely think awareness will save lives. I’m reaching out and am prepared to be very candid and honest about what I did to get to this point. Kind regards Luke

i love vitamin T

@DynamicAthleteHub

Ай бұрын

Naww dawg give me that vitamin bpc 157

BPC157 and TB500 are often called the Wolverine Stack.

@mitchellhooperstrongman

2 ай бұрын

It is hugely helpful, but make sure to go through professionals -- blokes.co

@BrandonBigB956

2 ай бұрын

They definitely work! They don't want these to be made legal as it takes away from big pharma and what they make money on. I swear the fist dose made a difference.

@WinnerMentality

2 ай бұрын

@@mitchellhooperstrongman what sites best to go through for Barrie ontario??

@Cousin.Justin

Ай бұрын

​@@WinnerMentality peptide warehouse

Love the honesty

You gained huge respect for this one

Great episode. I sure everyone can appreciate the transparency. I'm a big advocate of blood testing. I'm on hormones and get mine taken every 3 months. Haven't tried any of these peptides. Maybe something for me to look at though. Help with all the DOMS I have between sessions.

@mitchellhooperstrongman

2 ай бұрын

Peptides can be a great solution. Head to blokes.co to get a proper consult to know what you should be taking

@TheMortalKombatent

Ай бұрын

You should not need help with doms ever. Natty or unnatty doms should only be a thing for the first week or two after a long time off

the bpc 157 shoutout is solid

@mediumchicago_pizza

2 ай бұрын

it also might give u more girth lol

@Vincent-fv1ch

2 ай бұрын

@@mediumchicago_pizza what? explain this and provide evicence pls

@98vuxs70cigxocp

2 ай бұрын

@@Vincent-fv1chfor science

@mediumchicago_pizza

2 ай бұрын

@@Vincent-fv1ch just some dude’s anecdote on substack lol. i can look for it later but yea the dude said he had some growth

@cd66061

2 ай бұрын

@@mediumchicago_pizzathe mrs would be like 😮

These episodes are amazing 👏.

Amazing work sir 💪🏽💪🏽💪🏽

Love this, but hormones aren't just derived from cholesterol. They are amino acid and peptides too. Insulin is a peptide hormone

This was enlightening and informative. I found you did much more talking than the expert though. Good video!

@Jjunclejj

2 ай бұрын

Yeah there was no reason for that guy to be there

Love these videos champ 🏴󠁧󠁢󠁳󠁣󠁴󠁿

You are brave for doing this! LHBK!!!

@wileecoyote5749

2 ай бұрын

There's no backlash in the sport. Nothing to lose

@thecruellestmonth

2 ай бұрын

Brave for talking about perfectly legal compounds?

But what's the stack?

@virtualrealityfitness283

2 ай бұрын

Strongmen don’t talk about that 😂😂

@Voidrunner01

2 ай бұрын

@@virtualrealityfitness283 If they did, the content would get taken off youtube. One thing is talking about it in an academic abstract manner, another entirely is telling people what and how to take.

@bruuhhhh

2 ай бұрын

​@@Voidrunner01Mitch said it's an ethics thing. I guess he doesn't want to influence other people to take stuff, which is completely respectable imo

@FBI--OPEN--UP---

2 ай бұрын

Would be stupid to answear bacouse other Strongman or begginners would copy and thats stupid

@Voidrunner01

2 ай бұрын

@@bruuhhhh Oh, I'm sure it is. But KZread would still nuke the content because the second you start providing instructions on HOW to take illegal drugs, you get into some super sticky legal territory, and they don't want any of that heat.

Doesn't it at 14:55 say that it induces metastasis and resistance to a chemotherapeutic drug? Isn't that literally the opposite of stopping cancer? Or am I misunderstanding what "induces" means?

@heitooooor

2 ай бұрын

Good catch

@R0B711

2 ай бұрын

It was not used to reduce tumor growth like Mitch said, but it was an example of where those peptides are from. So partly wrong with the study, but his point about it being found in a medical study and then carried over to other fields was right. The peptide being the problem and not the solution here is not his point, even though he seems to have it wrong.

@minemilx2702

2 ай бұрын

@@R0B711 Quite a significant mistake. Some dude could end up taking it in the belief that it is anti-carcinogenic when it is in fact the exact opposite.

@R0B711

2 ай бұрын

@@minemilx2702 right, it is a significant mistake. But I think he made very clear, he isn‘t an expert to take medical advice from. Tbh, no cancer advice, even from an expert should be taken from youtube.

Terrific video.

Awesome video.

I hope this leads on to video about full ped use. great to hear your perspectives

@pauldavies7251

2 ай бұрын

Don't be so naive ffs 🤦‍♂️

@toby4598

2 ай бұрын

​@@pauldavies7251naive about what exactly? Things have to open up at some point. Obviously, sponsors don't want it. But, I choose to be optimistic that people will pave the way to PED use becoming more open soon.

@Lucas_Jeffrey

2 ай бұрын

He can't talk about AAS. It's unethical to even discuss it. Everyone knows Strongmen use AAS to be competitive. But the appropriate action is not to discuss it, to not inadvertently encourage viewers and fans to consider it for themselves. EDIT: Peptides are different. As simple amino-acid chain messenger proteins, the risk profile is like

@toby4598

2 ай бұрын

​@@Lucas_JeffreyUnethical according to you. In my opinion, the experience of trusted public figures is very valuable. Especially given the fact that most pro-strongmen will undoubtedly be able to talk about side effects they have experienced and reasons to not take PEDs. Keeping everything in the dark doesn't stop people using PEDs, it just leads to them doing so less safely and to making preventable mistakes.

Great video series

Love the series Mitch.

@mitchellhooperstrongman

2 ай бұрын

Thanks mate!

I just received my first peptide order of BPC/IP coincidentally. Thanks Mitchell.

@DadGetsFit

2 ай бұрын

Let us know how it works! I've been interested I'm trying them because I don't wanna use gear but I love being strong and want to get the most out of my body while I can (I'm 38)

@stevelee3144

2 ай бұрын

Bpc 157 mixes with 500 works incredible. There’s a reason why it’s called the Wolverine drug. Was Peptide science

2:46 "and then we call that a protein" Shows a picture of DNA...

@justinstuart9109

2 ай бұрын

Then confuses steroid hormones for all hormones, forgetting peptide hormones exist

@ArichManas

2 ай бұрын

@@justinstuart9109 But keeps mentioning insulin which IS a peptide hormone :D

@AlphaLionTrillionaire

2 ай бұрын

It is a protein 🤦

I love learning new things.

Only 5 min in and man i look at this stuff but missed most this information some how super cool huge thanks for the information man

Loving the content but if you're doing a series called "No stone unturned", why don't we discuss the topic of steroids? I dont mean this in a negative way at all and I think you should steer clear from promoting it, but you're doing the exact opposite of the series name by leaving a very specific stone unturned.

@derrickmorgan6220

2 ай бұрын

It's just like any bodybuilder only they use the ones for strength

@robothug6688

2 ай бұрын

Or what about dick size. We need to know. No stone unturned

@JB-qt3wo

Ай бұрын

The reason why he can’t is because steroids are schedule 3 drugs and possession is a felony crime in the US. Openly discussing the use of steroids online is essentially admitting to a crime publicly, which could then be used in court against him as evidence that he uses steroids, in the off chance that he gets caught in possession of them.

14:55 TB4 isn’t use to treat cancer but rather it causes cancer (and spread of cancer) and resistance to anti-tumor drugs… You should double check your statements before uploading video on such sensitive topics.

@haydencapps

2 ай бұрын

I dont think thats quite accurate either. I believe it is hypothesized to increase cancer growth if you have cancer, but not cause the cancer itself. This is because it causes increased angiogenisis, blood vessel development, which in theory could feed cancer cells more since one of the bodies defenses to cancer is to reduce blood flow/nutrients to the area to starve the cancer growth.

@Nattysuperman

2 ай бұрын

@@haydencapps It has broad range of function, not just angiogenesis that includes promotion of cell proliferation, invasion, migration also. So not only it could cause cancer but it promotes the invasion and metastasis of cancer. Either way this should alarm people. But If you are World’s Strongest Man, your every statement makes an impact on the mind of your loyal followers. He should take some accountability and closely watch his statements.

@haydencapps

2 ай бұрын

@@Nattysuperman oh, come on, is no one expected to be an adult anymore? If someone takes anything, whether its a pharmaceutical, a supplement, the food they eat, or a research peptide like this, thats on them. They are responsible for themselves. Many pharmaceuticals that people take all the time have just as significant risks and they are recommended all the time. key word here is - could. It also "could" have mechanisms promoting the prevention of cancer as well for all we know. By improving the function of the immune system destroying harmful mutated cells, or by promoting healing as cancer can be caused by repeated tissue damage leading to mutation. All we can really say is that it is a research peptide and not a lot is conclusively known about it, so take at your own risk. Like anything else really.

Outstanding in your industry!

This video is actually amazing.. love the edits keep this shit comin

There are no tests in mr olympia and wsm. Thats that game

@warlordmel

2 ай бұрын

There isn't in ANY Strongman comp, no matter the level... Not just top shows...

@justnii2056

2 ай бұрын

@@warlordmel there are actually natural wsm which are tested

@warlordmel

2 ай бұрын

@justnii2056 Wait what? Never ever heard of?? 🤔 Is it a new thing? But still, prob ppl use gear, just not doing any comps, get off the gear, then sign up as a competitor get tested, do the comp.. Win... I mean ppl are tested In the Olympics as well, ppl get caught 24/7.. IF you in the future could see if anyone EVER used Roids etc, tested ppl and had a competition... You know it, the weights would be way lower.. Doubt any of those in a Tested WSM been natural all their lives 🤷‍♂️

@Lucas_Jeffrey

2 ай бұрын

@@justnii2056 I've never heard of this, but it makes sense and I'd be interested to see some content on it. Strongman is so destructive, dangerous and rife with injury, it seems almost foolhardy to do it without enhancement. Steroids Vs. Strongman, it's almost the lesser of two evils.

Slight clarification needed. Not all hormones are cholesterol based (steroids). Insulin, for example, is a peptide hormone. Any endogenous chemical with a widespread regulatory function in the body (I.e. an endocrine function) is a hormone.

@mitchellhooperstrongman

2 ай бұрын

Oversimplification leaves out these details, thank you for giving more info!

Great insight

Love this series it's absolutely amazing keep it up

we really really really really need to get mitch on JRE!

If you don't have your health, you don't have anything.

@MrAmadeus1998

2 ай бұрын

If you don’t have chicken, you can’t have chicken and rice.

@roberthowe2910

2 ай бұрын

Well said..

This series deserves so much more exposure.

@mitchellhooperstrongman

2 ай бұрын

Please share!

This edit is so friekin cool!

@mitchellhooperstrongman

2 ай бұрын

Thank you!

Ipamorelin, bpc157, melanotan 1&2, kpv, motsc....all caused me to have horrible side effects. There is no such thing as a free lunch

@UniquelyUbiquitous-yg3xl

2 ай бұрын

What happened with each compound, man?

@Juggernaut-fg2up

2 ай бұрын

@@UniquelyUbiquitous-yg3xl ipamorelin causes me to get severe intestinal impactions, it causes my ears to swell up start leaking clear fluid and get scabs inside of the ear canal which eventually moves to the outside making the ear so tender you can't touch it. Never exceed 100 mcg. Bpc caused anhedonia, depression, auto immune response causing my body to attack my joints so now I have what seems to be permanent joint problems, it took all the joy out of everything made me miserable for six months from a single week of microdosing 10 mcg. M2 caused severe intestinal impactions, extreme nausea, some vomiting. At only 20 mcg Kpv caused me to get so severely dehydrated I almost went to the hospital, it also slowed gut motility Motsc makes me sleepy af and triggers an immune response as well

@Lucas_Jeffrey

2 ай бұрын

melanotan is crazy. risk of skin cancer for temporary aesthetics is nuts.

@Juggernaut-fg2up

2 ай бұрын

@@Lucas_Jeffrey one person told their doctor they thought their cancer came from melanota thats where thst came from. The actual studies show something else NIH.... "Topical MTII Therapy Suppresses Melanoma Through PTEN Upregulation and Cyclooxygenase II Inhibition Chronic inflammation is a key component in the progression of tumors [38]. Our previous study showed that the inhibition of inflammatory COX-2/PGE2 signaling contributed to the POMC-mediated melanoma suppression in vitro and in vivo [24]. This is in line with the present study which shows that MTII attenuated melanoma progression through COX-2 downregulation and PGE2 reduction at nanomolar scale in B16-F10 melanoma cells as well as in melanoma tissues. Recently, a positive correlation between COX-2 and PD-L1 expression has been delineated in primary and metastatic melanoma [39]. Furthermore, the application of COX-2 inhibitor celecoxib is capable of reducing the PD-L1 protein levels in human melanoma cell lines. Therefore, the COX-2-modulating function of MTII implicates its potential to serve as an adjuvant in combination with anti-PDL1 immune checkpoint therapy for the control of advanced melanoma. In summary, MTII exhibits anti-neoplastic effects against melanoma in vitro and in vivo. The anti-neoplastic mechanism of MTII is delineated through the activation of MC1R/PTEN signaling and the subsequent inhibition of the oncogenic AKT/NFκB/COX-2 axis. Hence, MTII may serve as a novel therapeutic adjuvant for the control of malignant melanoma."

@mitchellhooperstrongman

2 ай бұрын

100% agree, it all needs to be professionally advised and from reliable sources.

still waiting for a video on the difference in strength and performance for a trained athlete who uses nothing but natural food to help them perform vs an athlete who depends on man made pharmaceuticals. Just curious for your thoughts on the subject because of your educational background and personal experience

Class video Mitchell

@mitchellhooperstrongman

2 ай бұрын

Thank you!

When are we getting the anabolic steroid stack video?

Hey Mitch, have you already talked about PED's? Most of it is obvious, but will you talk about the different types and go into detail? It's been quite a taboo on youtube, but the series is called "no stone unturned." Guess I'll have to wait and see.

@busabros2480

2 ай бұрын

he's basically already answered that question in the "supplements" episode. the answers no.

@Blueswailer

2 ай бұрын

He already inferred/said in the beginning of the supplementation episode that he won't delve into that area.

@bruuhhhh

2 ай бұрын

He said he doesn't feel it's ethical to cover specifics, I would assume because he doesn't want to influence other people to do the same thing

@Fitsuuu

2 ай бұрын

@@bruuhhhh Which is fine, I don't need to know his stack. I would just love to hear his opinion on the subject

@GG-EZPZ55

2 ай бұрын

​@Fitsuuu I think actions speak louder than words. The fact every high level athlete takes gear rather it's strongman, PL, arm wrestling whatever, should tell you their opinions on the matter. If you want to be a high level competitor, there isn't a debate on what you have to do.

Really enjoyed that 👍💪

So refreshing From a guy at the top, I do appreciate the fact that your hhonest and Well articulate 💪

The absence of reference to PED usage in this series is glaring. It's also borderline unethical given the obvious usage in professional strongman. And that's not a criticism. It's an acknowledged aspect of the sport, and it is not tested - so go ahead and do what you like. But talking about health, training, or technique and selling supplements without referring to the impact of PED use on performance is, in my personal opinion, unacceptable because it gives the impression that all things being equal (i.e. genetics) you can achieve a certain performance level through just those things

@mitchellhooperstrongman

2 ай бұрын

The average person should not be on PED's so I will not provide advice on them.

@TerriblyNice_Not

2 ай бұрын

@@mitchellhooperstrongman Of course not. The issue isn't you recommending someone should be, rather the complete lack of reference to them while discussing performance overall is the issue

steriods next?🙂

@ColdStone52

2 ай бұрын

This a joke ? 😂

@Washyourbellybutton

2 ай бұрын

Why would it be? It's completely legal in Canada. He can speak openly about it if he wishes.

@dappas8682

2 ай бұрын

He really should address the heavy steroid use in strongman if he’s being transparent…

@everythingstrength1485

2 ай бұрын

To hear them ALL tell it...their "natural"....my ass 🧐🙄

@TangoKilo-fp8uu

2 ай бұрын

@@everythingstrength1485There isn’t a single professional strongman that has ever claimed to be natural.

You are the first strongman who talks open about those things. Amazing and huge respect for what you do! Big fan

Thank you for having such an honest, transparent discussion on this subject.

Just tell the people your PED cycle , its not gonna change how great you are at strongman. But for us that train would be helpful to know

@ur-inannak9565

2 ай бұрын

All the common PEDs were created decades ago, what he takes is not going to be any different from the stuff everyone uses. T, Dbol, Primo, etc.

@Hhhlll7778

2 ай бұрын

Come on , it’s common knowledge what Strongmen use , there’s no benefit for him to discuss it here

@allylilith5605

2 ай бұрын

no, it would be harmful because too many people like you *think* it would be useful. him telling what he does exactly leads to tons of people blindly copying it without having any idea what they are doing and running the full risks without any reason. reach your natural limit, hire him or another pro strongman as coach and they will guide you properly if that is truly what you want. but if you arent on the edge of getting to the pro level naturally, dont bother trying to imitate a pro's cycle. it's harmful without benefits

@deltalima6703

2 ай бұрын

Anyone thats going to use steroids does already. Its not ethical to lie or not mention it, its just hypocritical.

@allylilith5605

2 ай бұрын

@@deltalima6703 he doesnt lie and does mention that he isnt natural. there are absolutely people who would start taking steroids or increase their doses just to imitate him. He's handling it perfectly: being honest and not pretending to be natural, but also not leading people down the path to do it themselves. counterpoint: anyone for who it makes sense to take steroids for performance, knows what to take, and doesnt rely on youtube videos for their information

10:38 “How does it make you a better dad and a father?” Wtf is this BS? Correlating peptide use to parenthood is a quite a choice. This sounds super religious/cultish

@lphtahoe

2 ай бұрын

Yup! That storyline was kinda surprising…. Especially when he goes onto call it ‘Russian roulette’.

@atodaso1668

2 ай бұрын

Did you not listen to what came afterwards? It makes it so that he can train heavy, be the WSM Arnold champ etc, and still have enough energy and mobility left over to play with his kid.

@TheQShow

2 ай бұрын

That was definitely a little odd, especially considering how far down it ended up. Although I understand his passion for the potential of peptides allowing folk to have a much better quality of life as they age

This series is so good, thanks for doing all the research for me Mitch 🧐

@mitchellhooperstrongman

2 ай бұрын

Make sure to subscribe and turn on notifications so you don't miss them!

@ollydaniel4880

2 ай бұрын

@@mitchellhooperstrongman Subscribed as soon as I watched you win the Arnolds UK, awesome to see!

Mitch we really appreciate you opening up on this. For anyone who can read between the lines all the info is essentially there. One thing Im still curious about is what methods you had deployed in 2022 before really taking off with the big wins.

So basicaly this is a video to sell peptides.

Shouldn't call it no stone unturned if you're not going to talk about everything like steroids

Thanks for sharing your personal experience on this controversial subject.

Love Mitchell’s accent. Feels like every sentence ends with 🤙😎👈👈

Eat real food! Piss on the peptides.

Pregnancy is inherently dangerous. We prescribe birth control because the (well studied, widely documented) side effects are significantly less than the risks associated with pregnancy. Taking hormones to maximize athletic performance is not in the same realm at all. I'm not saying that, if safe, it shouldn't be allowed. Just that the two are not equivalent, or even really related ideas. And for the very small fraction of people who have pathologic hormone profiles, those are appropriately treated.

@allylilith5605

2 ай бұрын

there are other very easy ways to prevent pregnancy. for performance and other things, not so much edit: your argument would make sense if birth control pills were about making pregnancies safe, not about temporarily preventing them

@DiesIrae3434

2 ай бұрын

@@allylilith5605Hormonal implant or IUD are the most effective forms of birth control. Copper IUDs are an option, but side effects are not well tolerated by many. OCP or patches are not as good, still hormonal. Condoms are another tier down; given typical use, almost 1/5 women will become pregnant if they rely only on condoms. And again, we're talking about taking a medicine to avoid an unintended effect, versus using chemical means to change your body in some way. Again, I'm not completely opposed, I'm just saying they are not comparable aims. You can have all of the health benefits of exercise without taking PEDs/peptides/what have you.