NSAIDs | Non-Steroidal Anti-Inflammatory Drugs

In this video, Dr Mike explains how NSAIDs work! He discusses the role of prostaglandins in the body and how different NSAIDs like aspirin, ibuprofen, diclofenac, naproxen, and coxibs target enzymes called COX-1 and COX-2 to try and stop inflammation, pain, and fever.
He also outlines the relevant side effects for each type of NSAID.

Пікірлер: 88

  • @JenniferLee-26
    @JenniferLee-26 Жыл бұрын

    Your videos are the only ones I actually enjoy watching to study. Actually, it’s less about studying and more about stimulating curiosity, appreciating how cool the human body works, and that great feeling you get when you finally understand something that has gone over your head before. You’re the best, Dr. Mike!

  • @reviewpharmacy
    @reviewpharmacy Жыл бұрын

    You are master in explaining the concepts.

  • @Joannapl111
    @Joannapl111 Жыл бұрын

    i study pharmacy n i watch these videos everyday for three years now! thank you is not enough!!!

  • @tammyomerza8043
    @tammyomerza8043 Жыл бұрын

    Another great Video Dr. Mike thanks for all you do!

  • @dabeezkneez8716
    @dabeezkneez87168 ай бұрын

    This was probably the best explained and most useful information I have watched in the past month on youtube. Thank you🙏🏾.

  • @Javi_G21
    @Javi_G21 Жыл бұрын

    I'm not going to lie, I'm not too big a fan of how the new videos speed up when you write. One of the main reasons I love your videos is because the buffer time of explanation and writing, helps me process. Now that it is sped up, my mind doesn't have, what used to be, a beneficial processing time. Just thought I'd throw this out there incase I'm not the only one.

  • @DrMattDrMike

    @DrMattDrMike

    Жыл бұрын

    Good to know!

  • @gina4168

    @gina4168

    Жыл бұрын

    I agree. Great video otherwise.

  • @reneedavenport5817
    @reneedavenport5817 Жыл бұрын

    Love you sooo much, Dr. Mike. This information is so helpful…. Like everything else you selflessly share. ❤❤❤😊

  • @reseking6119
    @reseking61195 ай бұрын

    Dr Mike!! You’re awesome! Thanks for breaking it down and making it easy to understand. I appreciate you and your team!

  • @angelaflynn8747
    @angelaflynn8747 Жыл бұрын

    Love your videos, please please can you do something on "how local anaesthetic works". I hate having to look for other sources, as they never compare.

  • @sky_laithalhaidary4238
    @sky_laithalhaidary4238 Жыл бұрын

    Thanx for everything you share🫶🏻

  • @leyllafarooq6463
    @leyllafarooq6463 Жыл бұрын

    Your videos are really helpful for pharmacy students. For future videos would you also do videos on other drug classes and their moa. Thank you for your videos!

  • @Ouki99

    @Ouki99

    Жыл бұрын

    100% agree on both points ❤

  • @mattbhmb98
    @mattbhmb984 ай бұрын

    Amazing content, you sir explain things way better than most lectors I have!

  • @alisaalspach7737
    @alisaalspach7737 Жыл бұрын

    Love your explanations. Thank you!

  • @jaimeelliott6154
    @jaimeelliott61548 ай бұрын

    I dont know what i'd do without you! You're a legend . thank you. when im a rich osteopath ill send you some well deserved dollarrrr x

  • @Seaweed-oi5pl
    @Seaweed-oi5pl9 ай бұрын

    Your channel carried me during nursing pre reqs and now I'm back as a nursing student, thank you!

  • @brotherweitalk
    @brotherweitalk9 ай бұрын

    Great explanation! Super easy to understand even as someone without any knowledge.

  • @crystalrubbie9383
    @crystalrubbie9383 Жыл бұрын

    where have you beeen all my life life life !!!!!! this was amazing Dr

  • @jamalmusic6034
    @jamalmusic6034 Жыл бұрын

    thank you doctor for the best explanation... subscriber from malaysia 🇲🇾

  • @superstar50281
    @superstar50281 Жыл бұрын

    Love all your vids. Are you able to please do one on the side effects of corticosteroids?

  • @Momandmeherbal
    @Momandmeherbal4 ай бұрын

    Why worries when there is Dr.Mike ...Hats off sir😊

  • @pz3j
    @pz3j Жыл бұрын

    First class job Doc. Thank you.

  • @DrMattDrMike

    @DrMattDrMike

    Жыл бұрын

    Glad you enjoyed it!

  • @SarkisKlinik
    @SarkisKlinik Жыл бұрын

    What is the longest duration of time and dosage that we can give acetaminophen and NSAIDS for elderly with chronic pain ?

  • @Hady_gg
    @Hady_gg Жыл бұрын

    Absolutely amazing

  • @awandemaxmpofu3763
    @awandemaxmpofu3763 Жыл бұрын

    Many thanks for your informative videos.

  • @user-xn2qh7fl7q
    @user-xn2qh7fl7q11 ай бұрын

    Very helpful information. Thanks Dr

  • @abdirahmanfarahjimcale3611
    @abdirahmanfarahjimcale3611 Жыл бұрын

    Thanks Dr Mike

  • @meetchaudhary1945
    @meetchaudhary194511 күн бұрын

    great explanation thank so much ....!

  • @yilbertlipinyuen7503
    @yilbertlipinyuen75039 ай бұрын

    Very informative video. Thanks very much

  • @dilipaweeratunga
    @dilipaweeratunga Жыл бұрын

    thank you dr huge Sri Lankan fan here!

  • @Arrow-999
    @Arrow-999 Жыл бұрын

    Hello sir, I am an engineer by profession and have nothing to do with medical science. But currently I am on a journey to get fit and muscular, and your bio video really helped me to understand the human body. I have a question to ask if you can please answer. When and why my body decides to use which energy source to fulfill the calorie needs. In other words when my body decides to burn fat , when to burn carb and when to burn protein for daily calorie requirements. And If I am in a calorie deficit, what will my body burn first and how much

  • @user-uk7uq4um3x
    @user-uk7uq4um3x10 ай бұрын

    you deserve more likes

  • @gladysjebichii2132
    @gladysjebichii21323 ай бұрын

    I wish i could like a thousand times yoi are very educative

  • @hayaalqadomi9493
    @hayaalqadomi9493 Жыл бұрын

    Thanx you are great. ما شاء الله ✨

  • @asifiqbal9994
    @asifiqbal9994 Жыл бұрын

    very helpful for me thank you so much.

  • @teri2466
    @teri2466 Жыл бұрын

    Wait, wait!!! What about acetaminophen? Nevermind. From wiki ☺️ Paracetamol (acetaminophen) is also a COX-2 inhibitor almost exclusively within the brain, and only minimally in the rest of the body although its not considered an NSAID since it has only minor anti-inflammatory activity.[3][4

  • @teri2466

    @teri2466

    Жыл бұрын

    Thanks for explaining NSAIDs, doc ❤️

  • @frankjesse4304
    @frankjesse4304 Жыл бұрын

    Great job 👏

  • @DrMattDrMike

    @DrMattDrMike

    Жыл бұрын

    Thank you! 😃

  • @jasongose2975
    @jasongose29754 күн бұрын

    Great stuff - what is the reason for the reduction of platelets from COX-2? Flush the wound to clean before clotting sets in? Also, why the fever for trauma? For infection I always thought body was making it's own environment hostile.

  • @doridenis1204
    @doridenis1204 Жыл бұрын

    I wish you were my uni teacher.Please upload more about pharmocology❤

  • @vaishnavikaremore9305
    @vaishnavikaremore93052 ай бұрын

    Loved it ❤

  • @canada959
    @canada959 Жыл бұрын

    Great video.

  • @DrMattDrMike

    @DrMattDrMike

    Жыл бұрын

    Thanks!

  • @MunyaradziMtangadura-mn2cm
    @MunyaradziMtangadura-mn2cm8 ай бұрын

    Very educative

  • @antoniocavalli5474
    @antoniocavalli54747 ай бұрын

    Crazy good video

  • @rishiraj2548
    @rishiraj2548 Жыл бұрын

    Thanks

  • @VishalYADAV-we4vu
    @VishalYADAV-we4vu Жыл бұрын

    Thanks 🙏🏻 from India

  • @DHILLONSAAB
    @DHILLONSAAB Жыл бұрын

    Thanks love from India ❤

  • @brotherweitalk
    @brotherweitalk9 ай бұрын

    Good content!

  • @fuadzinab4039
    @fuadzinab4039 Жыл бұрын

    OMG you are great❤

  • @R00ba
    @R00ba Жыл бұрын

    Omg You Are The Best Thank Yaaaaaaaaaaaaaaa

  • @user-ji3vt9mh5t
    @user-ji3vt9mh5t Жыл бұрын

    Nice content and first comment ☺️

  • @RZAYAHD
    @RZAYAHD Жыл бұрын

    amazing

  • @KloiKoch
    @KloiKoch9 ай бұрын

    I found that Meloxicam is classified as an COX-2 Inhibitor. Since Coxibs were banned, I assume that Meloxicam does contain some amounts of COX-1 Inhibitor as well?

  • @oona6161
    @oona6161 Жыл бұрын

    I am confused, why coxib is the one needed to have a dortor's prescription before you buy it, while the other NSAID has no need prescription, where as you said first few names of NSAID mention are dangerous on other function of the body. Sorry for my english. I Hope this could be answer. Why?

  • @ashlynningard595
    @ashlynningard5954 ай бұрын

    I was under the impression COX-2 works to dilate renal vasculature. Please clarify.

  • @m.a6894
    @m.a6894 Жыл бұрын

    Pls can u upload a video on the Krebs (TCA) cycle plssssssssssssssssssss😩😩😩💕

  • @dhillonamarsingh5033
    @dhillonamarsingh5033 Жыл бұрын

    Superb explanation 👌

  • @lizbethportillo2113
    @lizbethportillo21136 күн бұрын

    would someone mind explaining why COX-2 has platelet inhibition i thought when u get injured like a cut platelets are important to prevent blood from leaving your body. Did i misunderstand?

  • @aprilpoppytui
    @aprilpoppytui3 ай бұрын

    pecs are very distracting dr mike. had to keep going back to re watch certain parts as i was getting quite distracted

  • @badee8953
    @badee8953 Жыл бұрын

    *wonderful name huh*

  • @siirzeren
    @siirzeren Жыл бұрын

    Can you please add subtitles in videos🥰

  • @DrMattDrMike

    @DrMattDrMike

    Жыл бұрын

    Click the CC button 😊

  • @Eric-sq4hd
    @Eric-sq4hd Жыл бұрын

    what your thoughts on using NSAIDs to treat a muscle strain (such as a lumbar sacral sprain) - because I've read different research articles on this, some saying inflation is useful for tissue repair, while others saying reducing inflammation is better overall for healing

  • @tahibsalam7175
    @tahibsalam7175 Жыл бұрын

    Hello sir I am from India. Iam a MSc Renal Science and Dialysis Technology student.... And i need your help .

  • @bobwen3809
    @bobwen3809 Жыл бұрын

    Hi, I wish you could do better on your sliding filamet video. It is so extremely frustrating to see the same "explanation" repeated again and again whem it obviously doesn't work at all. Your video explains why the myosin and the actin filaments slide together and hold ONE TIME, resulting in a minimal contracrion of the muscle. It does however NOT explain why this process could happen repeatedly, resulting in a further shortening of the muscle. Once the myosin and actin detach, the filaments are pulled to their original positions since there is nothing mentioned that would hold them in place.

  • @user-ox6nc6ly7f
    @user-ox6nc6ly7f3 ай бұрын

    but who want to block cox-2? block healing...

  • @bigp3441
    @bigp3441 Жыл бұрын

    I’m allergic to them 😢

  • @BattleSymphony349
    @BattleSymphony349 Жыл бұрын

    All these cause of inflammation

  • @christalbott450
    @christalbott4503 ай бұрын

    Hi. Life and everything in in is created by God himself. The son of him, Jesus, forgave all of all things. Breathe in air.

  • @gabesalgado789
    @gabesalgado789 Жыл бұрын

    I have no idea what you're talking about.

  • @robertdaymouse3784
    @robertdaymouse3784 Жыл бұрын

    Dear KZread, please offer a way to filter Australians out of my search results. I am willing to pay your monthly membership fee if it is offered with the membership.

  • @bobjohn1555

    @bobjohn1555

    Жыл бұрын

    Thank for this incredibly necessary and profound comment.

  • @DrMattDrMike

    @DrMattDrMike

    Жыл бұрын

    I didn’t think my accent was that bad 😔

  • @cutteybee

    @cutteybee

    Жыл бұрын

    Sickening is what you’re.

  • @kimberlybrewer8547

    @kimberlybrewer8547

    6 ай бұрын

    ​@DrMattDrMike, certainly not! From the US here. Just found your channel today as I am desperately searching for something, anything to help with unbareable 😢pain and nerve pain in my that started from a bad dental injury in my early 20s. I since lost my teeth due to severe to me and my elderly parents by an extremely narrarsist sister. On gabapentin, hydrocode, and gabapenentin. Not helping. If there was a way to burn my nerve endings, I would.

  • @kimberlybrewer8547

    @kimberlybrewer8547

    6 ай бұрын

    ​@DrMattDrMike, certainly not! From the US here. Just found your channel today as I am desperately searching for something, anything to help with unbareable 😢pain and nerve pain in my that started from a bad dental injury in my early 20s. I since lost my teeth due to severe to me and my elderly parents by an extremely narrarsist sister. On gabapentin, hydrocode, and gabapenentin. Not helping. If there was a way to burn my nerve endings, I would.

  • @iflahmalik5596
    @iflahmalik55964 ай бұрын

    You're so underated 🤍.... Grateful to you❤️