Neurology | Upper Motor Neuron vs Lower Motor Neuron Lesion | UMN vs LMN Lesion

Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will present on the pathophysiology and characteristics of an upper motor neuron lesion and a lower motor neuron lesion (UMN vs LMN lesion). We hope you enjoy this lecture and be sure to support us below!
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#ninjanerd #UMNvsLMN #Neurology

Пікірлер: 965

  • @ismaelbarzani6064
    @ismaelbarzani6064 Жыл бұрын

    You deserve to be named as the father of explaining and teaching

  • @NenehAgan

    @NenehAgan

    2 ай бұрын

    where do we vote🥹

  • @selwynhenriques2614

    @selwynhenriques2614

    16 күн бұрын

    Very useful to understand difference between upper and lower motor neuron lesions ,really appreciate the ton of research you put in to give us such a detailed and simple to understand explanation .

  • @ArundhotiRay
    @ArundhotiRay3 ай бұрын

    Throughout the medical life I felt pain whenever I saw the word UMN & LMN because I didn’t understand these complexity. Thank God, I can die in peace now bcz I understand upper & lower motor neuron lesion. Thank you ninja nerd, you are the best teacher of this planet.

  • @imperfectmammal2566
    @imperfectmammal25663 жыл бұрын

    Best teacher to ever exist in this planet!!!!!

  • @rjkmdb

    @rjkmdb

    3 жыл бұрын

    So true

  • @hillsongirl1

    @hillsongirl1

    3 жыл бұрын

    His kids will be blessed, hope he does pass on his DNA

  • @MsElina28

    @MsElina28

    3 жыл бұрын

    Amen!

  • @Foodies28Joy

    @Foodies28Joy

    3 жыл бұрын

    True❤️😍

  • @prashant23ify

    @prashant23ify

    3 жыл бұрын

    Sir I have a dbout please help me solve it . If UMN lesion is present, obviously no signals are passed to lower motor neurons, so there should be less release of acetylcholine ….. so basically umn=lmn … why there’s a difference???

  • @sabaripaulmajumder5196
    @sabaripaulmajumder51963 жыл бұрын

    Love from INDIA

  • @Destinyschild777

    @Destinyschild777

    8 ай бұрын

    Same bhai, best teacher in the world

  • @piyushgadegone5107

    @piyushgadegone5107

    16 күн бұрын

    Ye Ranveer Allahabadia jaisa dikhta hai kya dosto?

  • @mimansa_sah
    @mimansa_sah Жыл бұрын

    Seriously - 4 hours of uni lectures - distilled into pure gold.

  • @dennishaji2830

    @dennishaji2830

    Жыл бұрын

    Facts my G

  • @djay909
    @djay9093 жыл бұрын

    How this man keeps going all from his memory without a single hiccup is beyond me 🤯

  • @evilreborn4088

    @evilreborn4088

    3 жыл бұрын

    Practice. He prepares every lecture. Then practice and then shows us the final product. He Is seriously good. All concepts getting cleared

  • @drdebocherry

    @drdebocherry

    3 жыл бұрын

    He is the Master of the Universe, as in Queen Song!

  • @ghadderd.3444

    @ghadderd.3444

    3 жыл бұрын

    صلي على محمد لا تحسدينه

  • @BrianHurd

    @BrianHurd

    2 жыл бұрын

    Pretty sure some of the minutia is on a monitor off screen (but I could be wrong!), but 90% he knows. He is a badass.

  • @seemo5681

    @seemo5681

    2 жыл бұрын

    @@ghadderd.3444 منجد فجعتني ليتها تقول ماشاءالله

  • @riturajmajumder2055
    @riturajmajumder20552 жыл бұрын

    Zach , you are like one of the best med teacher in the planet currently.

  • @SF-es3ff
    @SF-es3ff3 жыл бұрын

    So much respect to you, attempting to get into PA school and discovering how hard that can be! Your videos provide an in-depth understanding that I probably couldn’t get elsewhere this easily! May God bless you for all your efforts!

  • @josetrujillo738
    @josetrujillo7383 жыл бұрын

    The way you teach is honestly amazing! Thank You Zach! Shout out Kristen! Shout out Rob! Thank You Ninja Nerd Lectures!

  • @amelonlord654
    @amelonlord6543 жыл бұрын

    Liked it and enjoyed it, definitely. I am so thankful, I was always very interested in neurology but found it quite complicated. You make all the complicated concepts seem understandable. I coudn't ask for anything more. And you even tell everything with such a spark that makes me want to binge watch your neurology playlist! Who would've thought..

  • @neelamjha7955
    @neelamjha79553 жыл бұрын

    Ahhh!!!!! The most awaited video is here....🤩 Thank you Zach....I respect You and your work a lot...I really do...🤩🍰

  • @evelynperez2486
    @evelynperez24863 жыл бұрын

    I just wanted to say that I freakin love your videos! You truly helped me pass advanced anatomy in my grad program! You have a gift of teaching things very clearly something some professors do not know how to do!!!!

  • @aakashkumarsah8616
    @aakashkumarsah86163 жыл бұрын

    Neurology seemed so tough to me.You made it so easy zach🤗🤗. Thank you ninja nerd team❤🇳🇵

  • @thehunchbackgirl
    @thehunchbackgirl3 жыл бұрын

    I would travel across the world just to thank you in person, Zach!

  • @flypnay704
    @flypnay7043 жыл бұрын

    Zach & Ninja Nerds, you constantly blow my mind...in that good neuro way! This subject was so terribly taught at my medical school, thank you for making this clear!

  • @pavankumardurgad

    @pavankumardurgad

    8 ай бұрын

  • @grdainylung5216
    @grdainylung5216 Жыл бұрын

    Please share this video to freshers in medical school,it's fucking awesome,I have wasted years studying books trying to understand this but you clearly described in simple way.Millions thanks to you.

  • @jeffreyrayner5235
    @jeffreyrayner52353 жыл бұрын

    Thank you Zach. I have been recently diagnosed with MND and a fell into a dark space. Your lecture has clarified my case such that I can understand what I may or may not have. This allows me to understand and deal with what could have been a total despair.

  • @neethu4661
    @neethu4661 Жыл бұрын

    Being a medical student your videos are such a blessing to me... Thank you sir.. Finally understood it❤

  • @TheChartreusePenguin
    @TheChartreusePenguin7 ай бұрын

    I don't know how I'd get through medical school without you Zach! Thank you so much for teaching and sharing your knowledge - I literally don't know how to thank you enough

  • @britneyidapaulus750
    @britneyidapaulus7502 жыл бұрын

    This was aweeeesome😭 I am basically hours away from facing my end of term internal Med exams and this was so useful 💡, the light to the end of my tunnel 💗

  • @fatemahh9459
    @fatemahh94593 жыл бұрын

    Oh my God I have a neurology exam in the morning, you couldn't possibly have had better timing! I might cry with sheer relief and gratitude 🤧 Your videos are the only reason I'm surviving and feeling smart while doing it 😂❤️ Thank you soooooo much! I cannot possibly ever express my gratitude. You are a real inspiration!

  • @manishaprja
    @manishaprja3 жыл бұрын

    Thank you so much for this. Best teacher! No one taught this in so simplified form in medical school. It helped me a lot.

  • @tanziasharmin7364
    @tanziasharmin73642 жыл бұрын

    I was waiting for so many years for this video...passed MBBS some years back.. I used to memorize UMN &LMN Lesions.. But this time i wl never forget....Great teacher..! Wonderful way of teaching...

  • @jillybasu8300
    @jillybasu8300 Жыл бұрын

    You guys are awesome, insanely good, the best teachers! Thanks for a great lecture Zach, it has really helped me understand about assessing for UMN v LMN lesions 🧠🤩🤙🏼

  • @elizabethwetzstein-cm1jp

    @elizabethwetzstein-cm1jp

    8 ай бұрын

    You have no idea how helpful those content is. I appreciate you.

  • @sudeeptalapatra3982
    @sudeeptalapatra3982 Жыл бұрын

    understanding Mechanism behind all these hyper reflexia and hyper Tonia makes it easy to memorise.... also gives an enjoyment 9f understanding the actual concepts behind...Kudos to your team sir for gifting such an amazing lecture.❤️

  • @lifeingreatmoment5654
    @lifeingreatmoment56543 жыл бұрын

    The best teacher I am eagerly waiting for him twice in every week

  • @Desert-123
    @Desert-12314 күн бұрын

    This is the best video on the internet . Thanks for being short and so comprehensive !❤

  • @hsmith1180
    @hsmith11803 жыл бұрын

    you get a lot of love in these comments and it's well deserved. I rely on these vids so much to supplement my "scholarly readings" because you break it down into much more comprehensible language. I'm not exactly sure how you do it but you make it so much easier to grasp. I watch bits over and over to make sure I have the idea correct. You are a legend

  • @kyongvincent4385
    @kyongvincent43853 жыл бұрын

    Love his lectures. How he can remember that much info. Genius

  • @amirulazam5034
    @amirulazam50342 жыл бұрын

    3 years of doubt and confusion cleared in 1 hour lecture... THANK YOU VERY MUCH..

  • @amalomer3113
    @amalomer3113 Жыл бұрын

    I can't imagine my life without ninja nerd💗 I love u guys we owe u alotttt❤️ يارب كلكم تسلمووو

  • @cleopaschisanga5355
    @cleopaschisanga5355 Жыл бұрын

    You deserve tones of awards... This makes so much sense when examining CVA patients thanks so much ninja nerd🙏❤️

  • @scottwilson7633
    @scottwilson7633 Жыл бұрын

    Thank you for what you guys do. I've been using your videos all through undergrad and now in medical school, and I can honestly say that you are one of the main reasons I (and likely many others) have been able to make it this far. Ninja nerd will have a big donation coming their way after residency!

  • @spanishlatteMD
    @spanishlatteMD3 жыл бұрын

    so happy for you guys for what you have accomplished over the years! been here since 1st yr med school and I still am now that i am a graduating medical student! keep rocking you guys!

  • @obedbagona7402

    @obedbagona7402

    2 жыл бұрын

    Regards to MSU Med! - From ADZU School of Medicine

  • @danielpa8644

    @danielpa8644

    2 жыл бұрын

    In the MASS part of lecture - LMN lesions cause less protein synthesis (more protein degredation) then at 23:30 the muscle responds to a decrease in Acetylcholine by synthesizing more nicotinic receptors. How are new receptors being created when protein degredation is going on with a LMN lesion?

  • @honeybadger1621

    @honeybadger1621

    Жыл бұрын

    hi,I'm type 1 diabetic 46 years old 15 years have neuropathy. I broken my tibia bone 4 screws and rod in my leg now. my question diabetic people's fracture healing? also neuropathy can made problem for healing process?

  • @sudeeptalapatra3982

    @sudeeptalapatra3982

    Жыл бұрын

    @@danielpa8644 great qs Daniel.!..even when protein synthesis is less due to less Ach cell will try to make new and more nicotinic receptor so as to increase muscle pr synth with whatever protein the cell from the very beginning of UMN lesion and even in late phase it will destroy it's organelles To make N.receptors because it is the only means to maintain homeostasis for the muscle cell.

  • @melissamonreal9486
    @melissamonreal94862 жыл бұрын

    BLESS YOU!! You explained UMN vs. LMN in the first 5 min of this video better than my grad school professor did in a full semester. Thank you!!

  • @sheliapdd758
    @sheliapdd7583 жыл бұрын

    Really help me to understand neurology class clearly. Thank you Zach. You did it great!

  • @VERA-jo3ev
    @VERA-jo3ev Жыл бұрын

    THIS IS LIFESAVING, i have a neuro class in 2 hours and this just was PERFECT!

  • @guarkenchiman4427
    @guarkenchiman44272 жыл бұрын

    His spirit challenges every mind to thirst more for knowledge. Thank you for your energy and time

  • @rwuthenow
    @rwuthenow2 жыл бұрын

    That was amazing. Just basically taught about 400 pages of exam prep. Thanks for doing this. You have really exemplary teaching skills. I wish I could half as good a job.

  • @tylerp8062
    @tylerp80623 жыл бұрын

    Perfect timing. Great job guys you really help bring it all together at the same time hitting the small things people like to test about.

  • @Iminoamino
    @Iminoamino3 жыл бұрын

    Being a medical student the respect and love I have for this person is inexplicable! Thank you

  • @jyotisamanta4997
    @jyotisamanta49973 жыл бұрын

    Kudos and all the best wishes. This solved my never solving confusions ❤️

  • @musicbeachdance
    @musicbeachdance3 жыл бұрын

    Saving my entire existence in Neuro thank you for explaining the findings for fasciculations!! So easy to follow!

  • @mileyuli
    @mileyuli3 жыл бұрын

    I am so beyond thankful for this video! I couldn't understand the differences between them and was struggling and this was so so clear! Thank you so much you guys are life savers!

  • @sandrak4032
    @sandrak40323 жыл бұрын

    Amazing! I understood so many things in depth that I had been taught couple years ago

  • @marianapereira5370
    @marianapereira53703 жыл бұрын

    Amazing lecture as always! When are you guys releasing the video about the physical exam? Btw love your videos, been watching them since my first year in medschool and I'm in my fifth now, and it's a lot thanks tou you! Keep up the great work!!

  • @mosab_emad
    @mosab_emad2 жыл бұрын

    I swear this is the best lecture I have see in KZread ,, Sincere love and respect Doctor ,, YOU ARE AMAZING!!

  • @granitklippa
    @granitklippa2 жыл бұрын

    Best teacher ever! My wife has recently been diagnosed with Progressive Bulbar Palsy and this video really helps me understand the symptoms. I am a Nurse anesthetist by training, but never really paid attention to this topic in the past. Thank you for posting, keep it coming

  • @alih6953
    @alih69533 жыл бұрын

    Zach you are helping millions of people. I am praying for you and your family so that God grants you with health and wealth. Thanks

  • @ifrahakbar2283
    @ifrahakbar22832 жыл бұрын

    One word for you: KING!

  • @DOT368ER
    @DOT368ER2 жыл бұрын

    Best to explain MND! My dad passed away from ALS a few years back started with the bulbar. I’m having symptoms of LMN with fascinations. This definitely give knowledge to determine what one has!

  • @H-ton-R-tonSN7893
    @H-ton-R-tonSN78933 ай бұрын

    You're absolutely an amazing instructor, who feeds the whole world with knowledge through social media..

  • @arijoybhattacharjee6039
    @arijoybhattacharjee60393 жыл бұрын

    I love you Teacher ❤️... From India 🇮🇳

  • @malihahoque5460
    @malihahoque54603 жыл бұрын

    The way you connect physiology with medicine ; damn I'm in love !

  • @daniaizzah4335
    @daniaizzah4335 Жыл бұрын

    last year med student here and your videos are god-sent!! thanks Prof! Many loves from malaysiaaa

  • @mrindian5908
    @mrindian59082 жыл бұрын

    Thank you for the most woderful lecture with brilliant simplification of a complicated topic. I have one doubt - the inhibitory tracts from Medullary reticulo spinal nuclei are descending ipsilateral where as excitatory cortico spinal tracts are coming from opposite side of brain, so how these inhibotory tracts are damaged to produce hyperreflexia in UML when the UML lesion is actually on the opposite side of the brain. Pl clarify, thank you.

  • @obaidkhan2278
    @obaidkhan22783 жыл бұрын

    Pure class of love 😍😍❤️❤️❤️❤️

  • @EmmArwen
    @EmmArwen Жыл бұрын

    oh my god! i can not stop watching your neurology classes. i am a resident 5 th year in the neurology department. It is fascinating me after seeing you explain this staff!

  • @garycovington7925
    @garycovington7925 Жыл бұрын

    As someone diagnosed with PLS (Primary Lateral Sclerosis, UMN) over 29 years ago and heavily involved with PLS email groups then Facebook PLS groups (1400+ members) for around 25 years that's the best explanation I've yet seen! Thank you! 👍 The only thing I have issues with is the explanation of fasciculations as being LMN. Almost every one of the 1400+ PLSers in our Facebook group, including myself, have fasciculations yet I'm sure after 31 years from first symptoms I have PLS with UMN symptoms only. The connection between fasciculations and fibrillations measurable on EMG seems tenuous because most of us with serious fasciculations have had EMGs which show no LMN involvement.

  • @User-to7nb
    @User-to7nb3 жыл бұрын

    Just here to leave a like and a comment for the algorithm

  • @akatodemyrus6077
    @akatodemyrus60773 жыл бұрын

    I wish I could draw like him...

  • @setarehabdoli3115
    @setarehabdoli3115 Жыл бұрын

    You are literally amazing,for years as a postgraduate specialist I was struggling for this topic,,,,,if there is a magician,its you❤

  • @judithumeadi2704
    @judithumeadi27042 жыл бұрын

    Great revision session. Excellent teacher, delivered at just the right pace. Easy to understand and follow. Thank you!

  • @SameerShaikhAdventures
    @SameerShaikhAdventures3 жыл бұрын

    FIRST ONE TO COMMENT. HUGE FAN OF YOU SIR. LOVE FROM PAKISTAN❤ do reply to me 🤒😂 Stay Blessed❤

  • @NinjaNerdOfficial

    @NinjaNerdOfficial

    3 жыл бұрын

    Thanks so much!!!

  • @balavantbhaipatel1969
    @balavantbhaipatel19693 жыл бұрын

    My teacher is back.....whoooo

  • @NinjaNerdOfficial

    @NinjaNerdOfficial

    3 жыл бұрын

  • @joymutheu7737
    @joymutheu7737 Жыл бұрын

    You really explain in depth ❤️..most times we don't stop to ask why some things in medicine happen the way they do but you explain it all❤️😍

  • @lollolez7147
    @lollolez71473 ай бұрын

    Can't express how thankful I am, Appreciate the time you spend to teach us in such an efficient easy, and fun way.

  • @prasannabharathi2019
    @prasannabharathi20193 жыл бұрын

    You make the topic more interesting by saying the word "beautiful " again and again 😍😌😍

  • @andydonham8612
    @andydonham8612 Жыл бұрын

    Should be mandatory viewing for new PLS and ALS patients. Cleared so much up about the affliction. Thanks so much.

  • @mowsumisara1411
    @mowsumisara14113 жыл бұрын

    Everytime i finished any lecture by you i feel like uff i love your teaching techniques...also i think its your teachings that makes me love mediacal science...thank you a very very much...😊😊😊

  • @eman-ne2ng
    @eman-ne2ng Жыл бұрын

    42:33 that smile on your face made me smile, Zach. You love to teach and it shows, always! Appreciate everything you do :)

  • @haleeyzkhair4121
    @haleeyzkhair41213 жыл бұрын

    I have waited all day for this. Thank you Zach you are the best of all.!!!!

  • @humanbeing3177
    @humanbeing31773 ай бұрын

    What an extraordinary lecture you have prepared and made it available for free for real. I am so thankful to you.

  • @365bmmusic
    @365bmmusic2 жыл бұрын

    You are really good at what you do. I have been struggling to understand this stuff for years so you have really filled the gaps in my knowledge, so thank you Ninja Nerd, keep creating and explaining, looking forward to watching more of your videos

  • @kelechi2352
    @kelechi23523 жыл бұрын

    what a time to be alive.. I am blessed to have found this channel

  • @TheHaretahi
    @TheHaretahi Жыл бұрын

    I am a Japanese doctor first year. I am not good at English, but your writing boad is wonderful, I can understand neurology deeply. Thank you.

  • @zahraaammar2708
    @zahraaammar27083 жыл бұрын

    the best teacher and the best channel ever , you literally are saving lives !

  • @neliakalenga2462
    @neliakalenga24622 жыл бұрын

    Literally the best teacher anyone could ask for! My Med school life saver!

  • @atlantic7949
    @atlantic79492 жыл бұрын

    I have tried to understand why UMN lesion causes hyperreflexia, not even my teacher explained this in the lecture in our neurology block. But, I am glad we have you. TBH, We all need to fund this guy to open his medical school.

  • @Honey-nv9dp
    @Honey-nv9dp2 жыл бұрын

    I'm thankful to Ninja nerd for the most simplified yet difficult concepts. Thank you for making med school make sense 💖

  • @RailingMedia
    @RailingMedia Жыл бұрын

    I'm doing an elective, only a first year unit, and I have close to 5,000 words in notes from various sources on ALS. In absolutely none of them (and I'm talking books devoted to ALS) do they describe it anywhere near as clearly or sequentially as this video. What an amazing teacher, you're now bookmarked next to 2-minute neuroscience videos... I'll be seeing you along the rest of my psychology degree pathway :D Now to find suitable academic texts to reference for the knowledge that you shared in this video.

  • @mashudurebeccamulangaphuma8649
    @mashudurebeccamulangaphuma86492 жыл бұрын

    Thank you so much. I spent 4hrs trying to understand my lecturer's notes on UMN and LMN. Should have came straight to ninja nerd. You made things easy for me

  • @angelicab.6080
    @angelicab.60803 жыл бұрын

    I LOVE HOW I JUST GOT TO THIS TOPIC AND THEY UPLOADED THE VIDEO A FEW WKS BEFORE 🥺😭😭 thank u sooo sooo very much for helping me pass neuro 🥺💜☺️

  • @adeyemialexandra209
    @adeyemialexandra209 Жыл бұрын

    Sir, you are blessed with intelligence and the gift of teaching. Thank you for breaking down these hard topics

  • @saveetapurswani5316
    @saveetapurswani53163 жыл бұрын

    OMGGG I was waiting for this lecture and its here. you explain in the best possible way, cant thankyou enough sir, god bless youu

  • @LeFishe42069
    @LeFishe420692 жыл бұрын

    i am appreciative of your efforts, due to these videos, i have decided to pursue a degree in the medical field, in particular neuroscience, i think without this resource i would have remained aimless in life, and i attribute my newly ignited passion to you.

  • @zoyaakhtar8410
    @zoyaakhtar841021 күн бұрын

    Excellent explanation I've been struggling with this topic.... Now after watching your video, it's crystal clear. Thankyou so much

  • @qamaruddinkhan3847
    @qamaruddinkhan38472 жыл бұрын

    Best teacher for understanding concepts 💞 kindly at the end of every lecture, cover the whole board so that we can take screen shot as well for memory

  • @bulbul10188
    @bulbul101884 ай бұрын

    Things and books just made sense after a long while. Thank you so so much for this video. I really appreciate your enthusiasm, clarity of concepts and efforts Professor. 😄

  • @quratulainghori6735
    @quratulainghori6735 Жыл бұрын

    Hey Zach! Your content is helping me understand so many concepts that I might have missed during med school. Also, can I please make a request? Can you please upload a couple of lectures on CT Scan Interpretations, especially on Neurology as my little brain is having a difficult time differentiating sinuses from ventricles (A little exaggeration but you get it, right? Simply adore you, your hardworking team, and your content! More power to you.

  • @vinayakkapatral4246
    @vinayakkapatral42463 жыл бұрын

    My Zach doze for the day! I was reluctant to see neurology classes but .... now I am hooked! Zachcellent!

  • @dwarf0606
    @dwarf0606 Жыл бұрын

    Learning to be a canine chiropractor, and you’re video’s helped me sooo much. Thank you! 😃

  • @easymedicine3677
    @easymedicine36773 жыл бұрын

    i cannot express my gratitude , you really made physiology so simple for me thank you so much

  • @siddhantpradhan1419
    @siddhantpradhan14193 жыл бұрын

    This video is just gold I don't think anything is more precious than this Thanks Sir for all the effort , this lecture is so very helpful. I searched a month looking for this concept in all the places I could . Thank u sir Lots of ♥️ and respect .

  • @abdelgadireshaq3990
    @abdelgadireshaq39903 жыл бұрын

    This is what I was waiting for.. ✨Thank you so much.. Medical student from sudan❤️

  • @kimberlybarrameda1631
    @kimberlybarrameda16312 жыл бұрын

    Wow this video is amazing. I actually hate myself for not searching this topic 3 weeks ago. I should have mastered it by then. Thank you again ninja nerd!!!! Wish you all the best.

  • @heatherjean5674
    @heatherjean56743 жыл бұрын

    You are so talented at making difficult concepts more understandable. Your videos are an absolutely Godsend!!!

  • @Mercyforthewicked
    @Mercyforthewicked Жыл бұрын

    amazing and easy to understand video! my professors mentioned the results of the lesions but not why so i left with questions, but this makes it so easy to comprehend

  • @carriehope8152
    @carriehope81523 жыл бұрын

    I have been struggling learning this, you made it so clear. Thank you!!

  • @iApatheia
    @iApatheia3 жыл бұрын

    Very timely for my Neuroscience class! Thank you @Ninja Nerd Lectures!

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