This is a great video highlighting useful information. Quercetin and Luteolin are MCAS stabilizers.

@DrJasonPickel

11 ай бұрын

Hi, thanks for watching and the great comment!

Thank you for this vital information, Dr Pickel.

Thanks! Just subscribed. Have been looking for this info.

@DrJasonPickel

2 жыл бұрын

Welcome! Glad to help.

Thank You!!!

@DrJasonPickel

2 жыл бұрын

You're welcome!

Thank you for your information l m buying this for my Parkinson’s disease

@DrJasonPickel

2 ай бұрын

Thanks for watching!

Good to know!

@DrJasonPickel

Жыл бұрын

Thanks for watching!

I take 250mg of Luteolin a day. Love it, super easy to take as its a small soft gel (at least the brand I use). As a bodybuilder in my mid 40's, I will take any advantage I can take.

@Aheroswelcome14

10 ай бұрын

What benefits have you seen relative to body building? I have been taking it several months and have not noticed any difference in any degree

Possible adjunct to facilitate bladder "retraining" by calming the detrusor muscle.

@DrJasonPickel

2 жыл бұрын

Thanks for you comment!

Great information. Thank you for sharing! Does it have any side effects? I read something about it disrupting progesterone function. Could that also impact thyroid hormone function?

@DrJasonPickel

2 жыл бұрын

Hi, this was drawn from a study that was performed using synthetic progesterone - "progestin". The authors then correlated that if it blocks progestin, then it may block progesterone. This is not a correct correlation and there is no evidence that it interferes with natural progesterones. In fact, the end of the study - the conclusion really tells the authors negative view upon anything natural. Sad. Now this info is spread all over the internet that it interferes with progesterone - untrue. www.ncbi.nlm.nih.gov/pmc/articles/PMC3851288/

thank you so much for the video, looking for a good brand of this supplement , any suggestion? thanks

@9xqspx6

2 жыл бұрын

I am doing the same at the moment. Have you decided by a specific product yet? Seems like there isn't a huge variety of brands out there. I also read here ( www.mastcellmaster.com/documents/2021-01/Luteolin-supplements-All-that-glitters-is-not-gold-Biofactors-2020.pdf ) that a liposomal formulation might be better (much better absorbed), but then it seems like that all the brands they list with such formulation comes from the same manufacturer, which damaged my trust a bit. I'm also a bit puzzled why it is quite difficult to find luteolin supplements.

@DrJasonPickel

2 жыл бұрын

Hi Charles, my favorite that I take personally and use with patients (and also contains other great ingredients) is this- here is link: optimalhealthsystems.com/essential-protect#code=OHSPICKEL Keep us posted and thanks for watching!

@NOT-WOKE-007

2 жыл бұрын

@@DrJasonPickel Too expensive and also contains many other items other than luteolin.

Hey best natural AI you said was zinc right ?

@DrJasonPickel

Жыл бұрын

Hi Charlie, thanks for watching! I am sorry, "natural AI"? what was natural AI? Let me know so I can respond better.

David from nootropic experts say that bioavaiability is very low. Artichoke extract has luteolin and provides a better bioavaiability. What is better pure luteolin or artichoke extract?

@DrJasonPickel

Жыл бұрын

Hi, Thanks for watching! I agree that bioavailability can be low. Artichoke is okay and anytime you use a whole food you will get more, but the sources with highest concentrations are radishes, green peppers, serrano peppers, green hot chili peppers, chicory greens, and celery - in that order. I haven't seen the research that artichoke is more bioavailable, and it definitely isn't as concentrated as these listed. The "pure luteolin" in certain forms may be more absorbable - this study: www.ncbi.nlm.nih.gov/pmc/articles/PMC8206097/ found that the methylated derivatives of flavones displayed five- to eightfold higher permeability in the Caco-2 cells (colon cells). It was also found that these methyl moieties provided substantial protection from hepatic metabolic activity compared to the non-methylated flavones. This increased metabolic stability of these compounds is owed to the methyl groups masking the hydroxy groups and limits their ability to become conjugated. I choose to use this whole foods supplement where the whole foods are pre-digested by enzymes before they enter your system allowing for higher bioavailability - this is the formulation (it is a formula - not all luteolin) - optimalhealthsystems.link/Protect Great question and I hope this helps!

Hey so I’m looking to supplement with Luteolin as an a estrogen aromatase inhibitor, Would you have a recommended , specific dosage in mind ?

@DrJasonPickel

2 жыл бұрын

Hi Charlie, great for you! Most of my patients are on 50 to 75mg. I really like this supplement that also has many other great things and is a whole foods supplement: optimalhealthsystems.com/essential-protect#code=OHSPICKEL

@Charlie-hg4ne

2 жыл бұрын

Great thanks a lot

Hey what was the recommended cycle for this ? Was it 90 days one week off ?

@DrJasonPickel

Жыл бұрын

Hi, there is no researched cycle that I know of, but you body adapts - like with anything. So a week off should be plenty to reset. It can vary per person and the state of your health, and your goal with the supplement.

Hey Dr have a question would using luteolin to help aromatase be better taken in the morning or before bed ?

Dr. Pickle, the content is very health-promoting. So, can I stop quercetin and continue with luteolin.

@DrJasonPickel

Жыл бұрын

Hi Felicisimo, Thanks for watching! I have many patients who have switched and really like it. I use this formula that contains it: optimalhealthsystems.link/Protect

@andreas956

Жыл бұрын

So you don't take quercetin and luteoline at the same time? Why not? I take Quercetin mainly for my asthma.

Poxa poderia ter legenda em portugues😢

@DrJasonPickel

Жыл бұрын

Sorry! Hopefully we can find a way to translate videos at some point. Thanks for watching!

@jorgeluisrodrigues1322

Жыл бұрын

Reinaldo aqui mesmo no KZread tem cursos fantásticos que ensinam inglês do beabá ao avançado.Boa sorte.

Does it make you lose weight?

@DrJasonPickel

2 жыл бұрын

go to this link and check out a product call Lipolean CLA. It works very well typically. Link: us.fullscript.com/welcome/drpickel Have a great day!

If u can't absorb it wats the point!?

@DrJasonPickel

Жыл бұрын

Hi Darren, It is absorbable and oral forms do work. I usually find it combined with other ingredients like in this product: optimalhealthsystems.link/Protect Thanks for watching!

But lute Olin has extremely low bioavailability

@DrJasonPickel

2 жыл бұрын

Great point! Yes, so it is #1 extremely important to have a healthy gut and diet, but also the form is important - I prefer taking it from a non-synthetic/whole foods form of supplement. One study also showed that taking it with Chrysanthemum morifolium extract increased the absorption by almost 50%. It would also be important to increase Liver health and support the COMT gene for this - P5P will do this. The one I use is: optimalhealthsystems.com/essential-protect#code=OHSPICKEL I appreciate your excellent comment!

@charlessavoie2367

2 жыл бұрын

Piperine/coconut oil.

@DrJasonPickel

2 жыл бұрын

@@charlessavoie2367 Thanks for your input!

@itayoron

Жыл бұрын

Take it sublingualy