I GENUINELY wanna thank you !! You made every hard part easy and easily accessible ! Keep posting videos !

Thanks so much, I’ve been trying to figure this out for 2 hours go bless

Great explanation! I don't know how I will do all this in 75 seconds lol

Thanks for the video. I have a question regarding X-linked dominant disease like Charcot-Marie-Tooth disease (CMTX1) does the Hady Weinberg equation work for finding out the prevalence of the disease?

Meet you are a life saver. Cleared so many things just few days before my exam. God bless you

@avneetsandhu9433

6 жыл бұрын

hi.please can u clear my one doubt = in the question given at end we have to keep 1/5000 = to what q2 or 2pq.please reply soon and please tell how did u decide about that.i will be very thankful to u.

You are a legend!!! Great explanation

Loved the explanation on how the equation is derived , and also the bonus on XLR and AD diseases with Hardy weinberg !! Good going meet

@Meetpatel-pu6me

7 жыл бұрын

anil kumar thank you...mention your answer in a new comment if you know 😊

Thank you for explaining it sooo well : )

nice video but i have one doubt that we have to learn whether disease is autosomal reccessive or dominant.If yes then please tell about disesase frequently asked in paper.plz reply soon

hey patel this is the first video i have watched and certainly this isnt the last one :) youre doing a pretty good job keep up the good work..god bless you brother

@Meetpatel-pu6me

7 жыл бұрын

wajih ansari thank you brother...good luck for your preparation and exam :)))

Thank you SO much for this.God bless you!

1 question came in neet ug 2019 thanks for best explanation 😇😇

Hey...nice video lecturer...east to understand...thank u👌

Thank you so much.. i calculated and the answer i came up with is 1/6250000. is it correct ? Plz reply.

Thank you so much, Patel.

thanks a lot sir for making this so easy

Excellent. Thank you very much for clearing up such a simple principle.

@Meetpatel-pu6me

7 жыл бұрын

Welcome bro :))

Hi Patel, thank you so much for this video and do keep up the good work! Please I have a question...why did you say (at about 8.40) that the chance of Mrs. X being a carrier is 1? Isn't the chance of being a carrier always calculated as 2pq? Could you please explain why it is 1?

@nooraykhalid7498

11 ай бұрын

you are right. you have to multiply that q value with 2

Thank you SO much for this video!

Thanks! Great as always ANSWER: AD 2pq=1/5000 p=1 2q=1/5000 q=1/5000 *1/2 q=1/10000 q^2=1/100000000 I think!

@habib080

4 жыл бұрын

Why did you multiply by 1/2 ?

Can we solve autosomal dominant disease questions on it

thank you.. great One

it's getting better N Better :)

@Meetpatel-pu6me

7 жыл бұрын

wizvig subbiah haha thank you....getting new experiences and ideas after every video :)

loved it as usual:) thanks a bunch:)

@Meetpatel-pu6me

7 жыл бұрын

Nishi Chandra thank you doctor 👍

Can you kindly help me with it ? If I am wrong

genius at work

Thank you so much :) you are amazing

@Meetpatel-pu6me

7 жыл бұрын

ambreen hamid thank you very much :)

Thanks alot!

thanks Meet it made made my day really helpful

1/100000000....AD inheritance of hereditary spherocytosis so....2pq = 1/5000...p~1 therefore...2q=1/5000....and thus q=1/10000 and hence (1/q)2 =1/100000000....since (1/q)2 = homozygous diseased

Good presentation. I suggest it will better if you make it more precise and to the point.

Thank you for your explanation! For the question I got 1/100,000,000 --> Because if Prevalence of Hereditary Spherocytosis is 1/5000 which is 2pq where p = 1 then q = 1/5000 x 1/2 x 1 = 1/10,000 and since Hereditary Spherocytosis prevalence is q squared therefore it is 1/10,000 squared = 1/100,000,000... please let me know if I got it. Thanks

Bless you !!!

Pliz explain more topic abt cardio topic . Tq

Sakkhat Explanation! Cleared all the doubts. Thank you Mitra! Btw, Are you a Resident or what? :)

@b4birjupatel

5 жыл бұрын

So, Answer would be, 1/10^8 Right? Explanation: 2pq=1/5000 ----> q=1/10000 q2=1/10^8

Thanks, it's amazing

@Meetpatel-pu6me

7 жыл бұрын

Susa Aku you are welcome 👍

Amazing ! thank you

@Meetpatel-pu6me

7 жыл бұрын

511Freedom welcome :))

Boy with such beautiful handwriting strange !!!!!!!!! Anyway jokes apart it was really helpful Thaks alot :)

Wow! Thanks so much!

@Meetpatel-pu6me

7 жыл бұрын

Nicky Shanel you are welcome :)

great explanation

@Meetpatel-pu6me

7 жыл бұрын

Thank you :)

Why is it the you have put p +q = 1/1000...would you please explain...thank you.

Thank you so much

@Meetpatel-pu6me

7 жыл бұрын

harika raghu you are welcome :)

How are we supposed to do this in 90 secs?

Beutiful explanation.

@Meetpatel-pu6me

7 жыл бұрын

Sudhakar Kondaparthy thank you :)

meet bhai please make some video on lipoprotien metabolism Your videos are amazing literally

@Meetpatel-pu6me

7 жыл бұрын

Gul nawaz bhai, i will not be able to make videos in February but i will make biostat videos before that.

omg thanks i understand finally hehe

Is 2pq = 5000 ? Basically 2q=5000 ?

the last part about prevelance of AD disease , it equals = 2pq+q2 ( u said 2pq only ) Thanks for ur efforts patel

at 3 28 you said prevelance of disease is equal to q2 so in last scenario can 't you start it by q2 is equal to 1/5000 bcz it is prevelance of disease i think you missed some word or i have some misconception

@bhatiarahul18

7 жыл бұрын

taro abhar. anand thayo , spasiba balsoy , brat

@Meetpatel-pu6me

7 жыл бұрын

Bhatia Rahul haha jordar

For my answer I got .0282 (or .0278) is that right?

@noedelafuentejr.9283

5 жыл бұрын

It's [2][p][q] right so.. [2] [1] [1/70] = 0.0285 thats what I got

Is it 1 in 5000

For AD shouldnt the prevalence be (p^2 + 2pq)?

@b4birjupatel

5 жыл бұрын

Exactly. That's what I Thought! So what is the final answer?

awsom meet patel :) it helped alot but i have bg problem in maths, like i was knowing hw to solve question u had given in last but was unabl t find q value i knew 2pq is 1/5000 nd i hav t find out 2 x 1 x1/? =1/5000 nd that value l b q nd its square l be answe but hel ya i dnt knw maths

@Meetpatel-pu6me

7 жыл бұрын

komal girdhari Anil kumar has mentioned the explanation in the commnets....let me know if you can see that comment or not?

@komalgirdhari4495

7 жыл бұрын

+Meet patel jus saw it :) thanks alot got tye q value :) bt can u advice me on this maths thimgs coz constantly i have been makin mistakes in such typ question

@Meetpatel-pu6me

7 жыл бұрын

komal girdhari they do not ask tough mathematics. ..there are specific patterns for calculation so keep on practicing and you will master it...also calculation based questions require more attention and thinking..!!

@mariumrandhawa1866

4 жыл бұрын

Meet patel where ?

anything for calculating recurrence risk in genetics ! . its causing me headache :(

@Meetpatel-pu6me

7 жыл бұрын

Hend alsh kaplans notes and uworld questions will help...its about practicing more questions

@hendalsh2270

7 жыл бұрын

thanks for replying I will try that

Thank u so much sir fr making every hard concept easy😁

For generalisations and the sake of simplicity , all enzyme deficiencies are AR , and all structural protein deficiencies are AD (exceptions apply like CF) . Hereditary spherocytosis is an AD condition . So , prevalence in AD is provided by "2pq" >>> So , 2pq=1/5000. >>>>q = 1/10000 (because p is near to 1). Since homozygous diseased is given by square of q , q2 = 1/100000000

@Meetpatel-pu6me

7 жыл бұрын

Very nice anil kumar 👍🏼

@shivangirairai5235

6 жыл бұрын

👍

q2=1/5000 ;q=1/70 ....2pq =2(1)(1/70)= 1/35 ....... prevalance of homozy diseased ppl=1/70 plz corrwct me if im wrong :/

I don't understand why we have to multiply 1/500 * 1/2 * 1/2

@aliaaalia9758

5 жыл бұрын

Me2

@dr.jaymehta5790

4 жыл бұрын

That's the probability of having children having disease . That's why we have to multiply it with 1/4

GODSENT

0.0141*2

you saved me lol

I love you

Is the answer 1/10000

Hereditary spherocytosis can behave as AR or AD. If its behave as AR then the answer should be 1/2500 and if you consider it AD then it would be 1/10,000. LOL I guess, let me know if I am correct.

@zer0c00I

5 жыл бұрын

In first aid, hereditary spherocytosis is under AD. So I calculated the answer to be 1/10,000.

is the answer 1/100,000,000

@Meetpatel-pu6me

4 жыл бұрын

Yeah that's correct

1/10000?

@Meetpatel-pu6me

4 жыл бұрын

It's 100,000,000. I have given explanation in another video

@shivleengill4976

4 жыл бұрын

Do you have biochem notes from step 1? My exams is in April and i am struggling with biochemistry it would be a help ...

@Meetpatel-pu6me

4 жыл бұрын

@@shivleengill4976 Sorry but I don't have it. Use FA, that's the best