Ed Boyden: A light switch for neurons

Ғылым және технология

www.ted.com Ed Boyden shows how, by inserting genes for light-sensitive proteins into brain cells, he can selectively activate or de-activate specific neurons with fiber-optic implants. With this unprecedented level of control, he's managed to cure mice of analogs of PTSD and certain forms of blindness. On the horizon: neural prosthetics. Session host Juan Enriquez leads a brief post-talk Q&A.
TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes. Featured speakers have included Al Gore on climate change, Philippe Starck on design, Jill Bolte Taylor on observing her own stroke, Nicholas Negroponte on One Laptop per Child, Jane Goodall on chimpanzees, Bill Gates on malaria and mosquitoes, Pattie Maes on the "Sixth Sense" wearable tech, and "Lost" producer JJ Abrams on the allure of mystery. TED stands for Technology, Entertainment, Design, and TEDTalks cover these topics as well as science, business, development and the arts. Closed captions and translated subtitles in a variety of languages are now available on TED.com, at www.ted.com/translate.

Пікірлер: 264

  • @thisscreensucks
    @thisscreensucks13 жыл бұрын

    lol the directors comment at the end of "that might change a couple things" might possibly be the biggest understatement ever uttered

  • @dark14cs
    @dark14cs13 жыл бұрын

    This should be front page news , the implications of this research can not be understated. Bravo

  • @liquidminds
    @liquidminds13 жыл бұрын

    "That might change a couple things"... perfect closing :-)

  • @sunnyy3358
    @sunnyy3358 Жыл бұрын

    Thank you so much for doing this TED Talk. The amount of scientific progress that could be done with these type of discoveries Ed Boyden is working on is amazing.

  • @feelingfeni4798
    @feelingfeni47984 жыл бұрын

    5:20 He said if we could some how GENETICALY MODIFY YOUR NEURONS IN YOUR BRAIN AND EVERY OTHER ORGAN to be a light switch to turn on or off and see what happens to you... Oh wait, he forgot to phrase it in a logistical manner! Oops

  • @johntheactor
    @johntheactor12 жыл бұрын

    I like how they mention the singularity in the last minute and a half of the talk like it's nothing.

  • @KhanRec0rdz
    @KhanRec0rdz12 жыл бұрын

    Holy crap. My jaw dropped when he talked about the eyes! That's revolutionary!

  • @aang7505
    @aang75055 жыл бұрын

    Absolutely amazing! Any updates?? 7 years later??

  • @CheesemanXCV
    @CheesemanXCV13 жыл бұрын

    Excellent research, excellent opportunities. Extreme need for caution and responsibility.

  • @VanKlaunch
    @VanKlaunch13 жыл бұрын

    Absolutely enlightening and inspiring!

  • @Lifeintakes
    @Lifeintakes13 жыл бұрын

    Great video, thanks TED!

  • @brianvandenberg4467
    @brianvandenberg44675 жыл бұрын

    14:30 14:33 wow. How would you get FDA approval right??? !for human subjects..... Claim “Defense Services” Claim “Classified” Surely folks wouldn’t do something like this in the Dark....

  • @kidmecha
    @kidmecha13 жыл бұрын

    He is so calm about potentially controlling and/or changing our entire species. I hope he is an optimist (like me) and thinks that (once the technology is in use) we will all be mature enough as a people to use this technology for good and not evil.

  • @lovrosucic6780

    @lovrosucic6780

    Жыл бұрын

    Has your opinion changed in the last 11 years? (Still an optimist) Just curious :D

  • @deemanrt

    @deemanrt

    Жыл бұрын

    @@lovrosucic6780 great reply! This is absolutely a control mechanism. Now if only they could find a way to deliver self-assembling nano-tech in a small delivery package that everyone has to accept. Then simply install the lights in key areas and start a pilot programming test. Perhaps they could use large black lights that appear as streetlights? Just speculating here, of course.

  • @aflamewithintheflame

    @aflamewithintheflame

    9 ай бұрын

    @@deemanrt haha .... phones are everywhere they would work. all the cameras and 5g ... this is like the matrix but we are walking around... or are we lol.

  • @P00P0STER0US
    @P00P0STER0US13 жыл бұрын

    Juan was really poking the future with a stick there at the end. Imagine if one could download memories and upload them, either into the same person or another person.

  • @oldmcgroin
    @oldmcgroin11 жыл бұрын

    This man deserves more respect.

  • @1a1a1and
    @1a1a1and13 жыл бұрын

    This is sweeeeetttttttttt, loved the q&a ;)

  • @Uraffyouruse
    @Uraffyouruse13 жыл бұрын

    Great talk

  • @t3tsuyaguy1
    @t3tsuyaguy113 жыл бұрын

    @Ultra4 In it's simplest form, it's essentially a domino effect. One pair of sodium & potassium ions switch positions. This leads to a change reaction down the length of the neuron. Think of sports fans doing "the wave". Of course it's more complicated than that, but it's a common enough way of explaining the action of neural impulses.

  • @rpm297
    @rpm29713 жыл бұрын

    I kinda saw the 'download information into the brain' question coming. But how would you or could you teach the human brain to translate binary code, if you could? Would it be more effective than one's own natural curiosity? Could the brain be stimulated in such a way it could send one's learning capacity into hyper-drive? Wouldn't that over-stimulate the neurons and render them into a kind of burnout? More questions than answers for me in this one... must have possibilities...

  • @yaHARmeMATEY
    @yaHARmeMATEY13 жыл бұрын

    TED when are u gonna do these in HD!

  • @ez910503
    @ez91050313 жыл бұрын

    Fabulous. Absolutely fabulous. Perfect marriage of the physics and neurophysiology. Unbelievable.

  • @1schwererziehbar1
    @1schwererziehbar113 жыл бұрын

    this guy has the most beautiful animations.

  • @niniomigrania
    @niniomigrania13 жыл бұрын

    Sounds promising! Imagine very complex brain control with this, the possibilities are endless.

  • @joeymatee
    @joeymatee11 жыл бұрын

    that was an amazing talk, i think without dry humour and silly pictures the audience was disappointed

  • @nehorlavazapalka
    @nehorlavazapalka13 жыл бұрын

    Am I the only one who sees the potencial of this becoming a torture device? I think that this will be one of it's first applications. It's much more easier to cause pain via this device than to substract memories from the brain.

  • @9009tubeyou
    @9009tubeyou13 жыл бұрын

    Interesting topic he have presented here. Imagine easy learning can be at schools if they had that kind of technology there.

  • @Driux
    @Driux13 жыл бұрын

    This talk deserves a standing ovation.

  • @aflamewithintheflame

    @aflamewithintheflame

    9 ай бұрын

    for being a complete psychopath yeah

  • @Driux

    @Driux

    9 ай бұрын

    @@aflamewithintheflameIgnoring this this is a 12yo comment of mine... That is such an odd thing to reply on two conceivable levels. You think he's a complete psycho for some undisclosed reason. You think he deserves standing ovation for being said complete psycho.

  • @JoeBrenan
    @JoeBrenan13 жыл бұрын

    Just amazing, this is why i study and love science.

  • @joshliu3964
    @joshliu39648 жыл бұрын

    This is still works in progress. Ed recently put up an AMA on Reddit. Hopefully psych meds will be a thing of the past

  • @rabia1180

    @rabia1180

    8 жыл бұрын

    can you please link me to the reddit AMA? I looked but can't find it!

  • @joshliu3964

    @joshliu3964

    8 жыл бұрын

    www.reddit.com/r/askscience/comments/4ak060/askscience_ama_series_im_ed_boyden_professor_of/

  • @rabia1180

    @rabia1180

    8 жыл бұрын

    Josh L thank you Josh!

  • @jain355

    @jain355

    7 жыл бұрын

    TThe Real ED Cure is ovеr 300 Yеars Old! twitter.com/a9c60516d47d92b7a/status/804602507225808896 Ed Bоydeеeen А light switch foor neurоns

  • @10bristol

    @10bristol

    3 жыл бұрын

    @@jain355 The twitter account is gone. Where can i find the information you talked about?

  • @13Septem13
    @13Septem1313 жыл бұрын

    Hope one day I could use technology he talking about for example to learn stuff without reading books but just uploading it into the brain. It is so exciting!

  • @brianvandenberg4467
    @brianvandenberg44675 жыл бұрын

    13:28 14:37 14:40 part of my #ivXXX Protocol.....the Eye Tracking “Software” Portion. M EYE 👁 Algorithms that learn to activate switches with single commands (Private Internal Voice Vibration Protocol 2cd edition). Look at a switch/Relay and say “On”...Receiver activates!!! All this 3 second delay....with “Hey Alexa” or “Hey Siri” going obsolete in 5 years..... What channelRhodOpsin will you pick?

  • @AntiProtonBoy
    @AntiProtonBoy13 жыл бұрын

    That blind mouse thing was ace.

  • @kablamo9999
    @kablamo999913 жыл бұрын

    Incredibly interesting!

  • @P00P0STER0US
    @P00P0STER0US13 жыл бұрын

    @SheepRCool17 What need? We already have television, radio, cheap food, fatigue, and myriad other elements to keep us doing what we're expected to do. The idea of a physical implant used for that seems clunky. I think it's truly marvelous if such things can help people afflicted in such a way that this can help.

  • @nehorlavazapalka
    @nehorlavazapalka13 жыл бұрын

    @hmspinaforethisisspa 100% sure that you are right.... but this can really become the worst torture ever

  • @stevenaudet
    @stevenaudet13 жыл бұрын

    This is so scientifically awesome!

  • @libanlibanliban
    @libanlibanliban13 жыл бұрын

    Truly amazing.

  • @MrPlatonist
    @MrPlatonist13 жыл бұрын

    @volound in that sense, yeah. but the way YOU said it, it seemed otherwise. iow, probably my mistake then. =)

  • @test123ok
    @test123ok13 жыл бұрын

    this is fantastic ! I can't wait till this becomes a real product.

  • @DeadWhiteButterflies
    @DeadWhiteButterflies13 жыл бұрын

    Downloading memories. Bladerunner much? :D Great talk though.

  • @Redflowers9
    @Redflowers911 жыл бұрын

    Ed Boyden was a *prodigy actually, he worked for MIT as a teenager.

  • @bryanm6080
    @bryanm60803 жыл бұрын

    Anyone here in 2020 based off of Neuralink? Was looking at professors to start a masters in neuroengineering, came to search for Dr. Boyden @ MIT!!

  • @SkiesAhoy
    @SkiesAhoy13 жыл бұрын

    @andy3071190 Noise that you have to endure? Oh please. There's a very obvious mute button which you can use for those few seconds, if the starting music is really THAT aggravating.

  • @TerielAtmano
    @TerielAtmano13 жыл бұрын

    Wow. Now THAT are ideas worth spreading.

  • @ngarcia257
    @ngarcia25713 жыл бұрын

    This is awesome... And this needs more views...

  • @damoninsky
    @damoninsky13 жыл бұрын

    @Icecoldpoker I think there should be science on every front-page. People need to pay attention and be more involved in its advancement. We should celebrate the incremental breakthroughs and build more confidence to lead us to bigger breakthroughs (such as vaccines, technologies, discoveries...not disappointments).

  • @yaHARmeMATEY
    @yaHARmeMATEY13 жыл бұрын

    @cristoretornebiblia then dont choose the HD options then :S

  • @vqly
    @vqly13 жыл бұрын

    @Dixavd It's more than fine, every time that mouse get a jolt of blue light it's feeling a jolt of dopamine, the brain reward system.

  • @LaBambathereal
    @LaBambathereal13 жыл бұрын

    i have always wondered... how does our body make electrical impulses ? There's no power supply, or is there ? Do we make some kind of biotic electricity ?

  • @SmushiSan
    @SmushiSan10 жыл бұрын

    Are there any sources for the information he's saying? Can someone help me get his lab journal somewhere?

  • @NateSonnenfeld

    @NateSonnenfeld

    7 жыл бұрын

    Just Google Ed Boyden, Karl Deisseroth, etc.Look up their names on Google Scholar, info's all out there.

  • @elyzavalerio52

    @elyzavalerio52

    4 жыл бұрын

    @@NateSonnenfeld kzread.info/dash/bejne/gJZkmbaFm62Zh9o.html

  • @Dixavd
    @Dixavd13 жыл бұрын

    @vqly yes I know, I understand it perfectly and every way it works and the fact that the mouse gets pleasure from the blue light but just like irrational phobias I can't help but feel uncomfortable when I see it connected to that thing because of allt he times I have been in hospital in my life with drips and canulae and things so anything being connected to an alive awake subject - thanks for trying though.

  • @Decimaster321
    @Decimaster32113 жыл бұрын

    The evolutionary developments that lead to the growth of neurology must have been amazing, producing a system that seems so far removed from basic chemical survival. I wonder if we will find out how these cell systems emerged in my lifetime.

  • @Phyrexious
    @Phyrexious13 жыл бұрын

    Madness..? THIS IS... AWESOME!!!!

  • @aang7505
    @aang75055 жыл бұрын

    Phenomenal!

  • @Desert2GardenLV
    @Desert2GardenLV13 жыл бұрын

    Someone please give this guy a Billion dollars. We need this.

  • @t3tsuyaguy1
    @t3tsuyaguy113 жыл бұрын

    Very clever.

  • @t3tsuyaguy1
    @t3tsuyaguy113 жыл бұрын

    @belliebum12 LOL! Actually, they'll probably need programmers to write the interfacing software. You'll have plenty of work. ;)

  • @MrBranboom
    @MrBranboom13 жыл бұрын

    'That might change a couple things' XD

  • @oicub2
    @oicub213 жыл бұрын

    @shade1978x 17:12 That does change things don't it ..

  • @MrBalcora
    @MrBalcora13 жыл бұрын

    If this research is successful, it will definitely change society

  • @YourCritic
    @YourCritic13 жыл бұрын

    Brilliant

  • @Rarae192
    @Rarae19212 жыл бұрын

    @andy3071190 I love that noise: bwwwwoaaaaaONGGGGGG!!! It wouldn't be a TEDTalk without it.

  • @ZeusLT
    @ZeusLT13 жыл бұрын

    @saurabhdelft to serve us

  • @Ko252
    @Ko25213 жыл бұрын

    This is genius.

  • @Volound
    @Volound13 жыл бұрын

    @MrPlatonist they do, actually. understanding my position and my arguments is a prerequisite for being able to think about them. isnt that obvious? but if you mean it literally, then i didnt make any such accusation, so strawman.

  • @FungusyHam
    @FungusyHam13 жыл бұрын

    woah, I read this in scientific american a couple of months ago. Cool stuff!

  • @rlinfinity
    @rlinfinity13 жыл бұрын

    @madzane94 Alga is singular. Algae is plural.

  • @ianmathwiz7
    @ianmathwiz711 жыл бұрын

    3:19 Migraines must be twice as common, seeing as they're listed twice :D

  • @charlesedwards5816
    @charlesedwards58163 жыл бұрын

    nice

  • @Lostpanda123
    @Lostpanda12313 жыл бұрын

    @juanarruti Thats true :D

  • @ChrisCapel
    @ChrisCapel13 жыл бұрын

    @abram730 Oops, yeah I meant Parkinsons... Soooo yeah...

  • @andreeaweed
    @andreeaweed12 жыл бұрын

    wow this is a great invention ...this is a genius

  • @matrixistrue
    @matrixistrue13 жыл бұрын

    @Driux AMEN BROTHER

  • @epicbrowndragon
    @epicbrowndragon Жыл бұрын

    Studied for 11 years…this then aired 11 years ago…and 11 years later what tech do we have using this?

  • @maxgunn555
    @maxgunn55513 жыл бұрын

    @TheFounderUtopia how is it ironic i dont understand?

  • @cronnyberg
    @cronnyberg13 жыл бұрын

    This can have so many amazing applications from curing sensory ailments to mental disorders, downloading binary information directly into the brain and even emotional manipulation (it could even lead to mind control lol!!!) It is only limited by our understanding of the human mind, which is ironic, because it could also be one of the foremost developments into studying the human mind too :D truly incredible!!

  • @DeanOSupremo32
    @DeanOSupremo3213 жыл бұрын

    Man so much good can come from this...but also evil

  • @browntown72
    @browntown7213 жыл бұрын

    @t3tsuyaguy1 lol yeah i meant it in a sense that "despite this breakthrough, the harsh reality is that this research will not be available to all". But yes, exactly, i was just expressing my frustation at the fact that brilliant research like this, or recent breakthroughs in cancer treatment ect. are not employed because it doesnt provide the biggest profit. I agree with that assertation, but i believe that fear is used to make money. Without money, they wouldnt need to cause fear.

  • @borderlinebuddhist
    @borderlinebuddhist13 жыл бұрын

    i find it depressing that this isnt front page news.

  • @holdmybeer
    @holdmybeer13 жыл бұрын

    kind of scary O.o but important also.

  • @kiddhitta
    @kiddhitta13 жыл бұрын

    @borderlinebuddhist well then there would be no room for the new episode of Glee's advertisement

  • @Icecoldpoker
    @Icecoldpoker13 жыл бұрын

    @ChalleFoV3 This is not a breakthrough - This work in neurogenetics has been around for half a decade and consists of many many many smaller experiments. Slowly but surely a consensus backing an idea is formed...... it does NOT happen overnight. I am not being pessimisitic - Just being a scientist

  • @madpuri
    @madpuri13 жыл бұрын

    @TupoyVolk Arts, Music

  • @roidroid
    @roidroid13 жыл бұрын

    you could use this to insert new receptors types into your retinal cells, which will be sensitive to radiation sources that we can't naturally see. Such as various wavelengths of IR or UV. And the sky's the limit, we could enable until we have expanded our visual colour range 10x, 1000x, 100,000x, why stop? I want to see X-rays, RF signals, Neutron radiation, anti-proton streams.

  • @t3tsuyaguy1
    @t3tsuyaguy113 жыл бұрын

    @dookiecheez My guess is both. When we fully understand the brain, we'll be able to refine the design. When we master genetics, will be able to engineer DNA that produces said design inside a person. I figure it'll be something like that anyhow. :)

  • @Spencerianism
    @Spencerianism13 жыл бұрын

    @maxgunn555 Too many brilliant people throught history have left cynicism (correct spelling by the way) by the wayside and naively embraced hope for an alternative to logical reason. The end result is always balanced towards disaster, not constructive creation. It's our very nature to be that way, and to do so.

  • @tunnis7us
    @tunnis7us13 жыл бұрын

    Finally good ted talk without stupid time consuming jokes in every sentence

  • @redsbr
    @redsbr13 жыл бұрын

    If even NOW one's "ability to learn" and one's "intelligence" is controlled by money, how does that shape our perception of the value of one's life. Will we let the market decide who is more valuable, the ones who can afford such enhancements? Or will we finally admit that all life, the smart and dumb, the strong and weak, the big and small, and the fast and slow... all life has INTRINSIC and EQUAL value. What will you decide, as we soon manipulate the most sanctic parts of ourselves?

  • @roidroid
    @roidroid13 жыл бұрын

    @P00P0STER0US It was kinda an embarasingly naieve question, "Oh so it's on and off, it's digital?". Juan reads too many sci-fi books, it's just another small development. It doesn't mean that in 5 years we'll all be uploading our memories, ffs what a jump Juan, these things take time and lots of further developments.

  • @FrankFloresRGVZGM
    @FrankFloresRGVZGM13 жыл бұрын

    Interesting, but frightening in the context of a for profit monetary system.

  • @roidroid
    @roidroid13 жыл бұрын

    @Th3CrimsnChin so deep

  • @GiffyPooh
    @GiffyPooh13 жыл бұрын

    Today I graduate with a Masters degree in Psychological Counseling... and I guess it's also the same day I change professions.

  • @nightmathzombieethan
    @nightmathzombieethan13 жыл бұрын

    Cool, AND scary.

  • @maxgunn555
    @maxgunn55513 жыл бұрын

    @TheFounderUtopia what makes his name ironic?

  • @LudicrousTachyon
    @LudicrousTachyon13 жыл бұрын

    You're brain is now an electronic I/O device. The epilepsy or depression applications still aren't cures. However, the blindness thing would be.

  • @ErichoTTA
    @ErichoTTA13 жыл бұрын

    I admit the name "Siemens" sounds funny.

  • @luiseguez8175
    @luiseguez817511 жыл бұрын

    oh my god

  • @Jotto999
    @Jotto99913 жыл бұрын

    Neurology and genomics will transform humanity!

  • @1993whitenoise
    @1993whitenoise12 жыл бұрын

    Only 31 thousane views... And a lil wayne video has how many?? Show me the justice in that...

  • @Volound
    @Volound13 жыл бұрын

    @saurabhdelft i disagree. i think that anyone i asked would realize my response addressed your argument and blew it out of the water. it shows you are just arguing from ignorance. and theres a certain kind of irony to someone accusing someone of being a "shallow thinker" who hasnt managed to grasp all of the rudiments of the english language, wouldnt you agree? but to answer your question, "what was the goal of black people, what was the purpose of black people in 1850 in the americas"?

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