Avery Experiment: DNA as the Transforming Principle
The Avery, MacLeod and McCarty classic experiment helped to prove that DNA is the molecule of heredity. Previously, it was thought that proteins were the most likely biomolecule that transferred inheritance information from parent to offspring.
Avery's experiment built on the foundation of Griffith's earlier work, in which he identified a "transforming principle" that allowed bacteria to acquire characteristics from one another. In the Avery experiment, they first used process of elimination to determine that neither carbohydrates nor lipids were responsible, then tested proteins, RNA and DNA. The scientists knew that bacterial transformation should still take place unless they disabled the transforming principle. They added enzymes such as proteases, RNases and DNases to destroy various components of the bacterial mixture, knowing that most mice would die except the mice who received the injection with the disabled transforming principle.
Guided Notes & Study Guide: Check out the BOGOnotes for this video!
etsy.me/3wlfh3g
0:00-0:38 Introduction
0:38-0:55 Biomolecules
0:55-1:47 Proteins vs. Nucleic Acids
1:48-2:30 Building on Griffith's Experiment on Bacterial Transformation
2:30-3:50 Preliminary Testing
3:50-4:03 The Diva Protein
4:03-4:26 Process of Elimination
4:26-4:57 Avery Experiment Design
4:57-6:24 Avery Experiment Results
6:24-7:12 Conclusions
Sources:
The Original Paper: www.ncbi.nlm.nih.gov/pmc/arti...
en.wikipedia.org/wiki/Avery%E...
openstax.org/books/microbiolo...
thebiotechnotes.com/2019/12/0...
#averyexperiment #bacterialtransformation #moleculeofheredity
Пікірлер: 19
Guided Notes & Study Guide: Check out the BOGOnotes for this video! etsy.me/3wlfh3g
This is literally the most underrated scientific channel ever. Thank you so much for these videos, they help a ton. Keep it up!!
@BOGObiology
2 жыл бұрын
Thanks, Zina! So happy to hear that! Please share with your classmates, if you feel comfortable doing that. Sending love and best wishes from Boston! -BOGO
@zinaalkharraz7752
2 жыл бұрын
@@BOGObiology Yes, will do!
I LOVE THIS CHANNEL. you guys helped me finally understand avery's expiriment! my teacher was SHOOK lmao
This was such an amazing video, it really helped me understand this experiment. Well done, and thank you
@BOGObiology
2 жыл бұрын
Thanks, Ann! Sending love and best wishes from Boston!
thank for this video! thank you so much!
thank you Doctor❤️
Nice presentation....
McLeod McCarty and Avery did their experiment invitro... so from where does the mouse comes
What does a 1.67 ratio entail? Don’t ratios usually have two numbers?
@readmesoon13
Жыл бұрын
1.67 = 5/3 ratio of 5 to 3
Helpful video, do you do zoom tutoring?
@BOGObiology
2 жыл бұрын
Thanks, Elham! Sorry, no zoom tutoring at the moment. Maybe someday! -BOGO
@elham2821
2 жыл бұрын
@@BOGObiology No worries, thx tho.
Here for Biochemistry class
@BOGObiology
2 жыл бұрын
Yes, lots of folks are haha. Sending good vibes from Boston! -BOGO
Thank you so much!