THE MOST BEAUTIFUL EXPERIMENT IN BIOLOGY: Meselson & Stahl, The Semi-Conservative Replication of DNA

Ғылым және технология

yourekascience.org/portfolio/t...
In 1958, Matthew Meselson and Frank Stahl published the "most beautiful experiment", where they demonstrated that DNA undergoes semi-conservative replication. In this video, we describe the experiments that lead to this discovery and why understanding how DNA replicates is so important. This video is a complement to Matthew Meselson's iBiology Discovery talk, where Meselson recalls the events that led him to meet Frank Stahl and to plan and execute these experiments.
This video was produced in collaboration with iBiology.
iBiology (www.ibiology.org) is a growing collection of free open-access online videos by scientists about research and discoveries in fields including cell biology, neuroscience, molecular biology, microbiology, ecology, development, and biophysics, and also features short talks on topics such as professional development, careers, policy, and education. iBiology is funded by NSF, NIGMS, and HHMI, and is supported by the ASCB and UCSF.

Пікірлер: 255

  • @victoriarobinson3958
    @victoriarobinson39588 жыл бұрын

    this was so satisfying to watch...your handwriting is GLORIOUS

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    @timmy18135

    4 жыл бұрын

    Kind of like Vihart

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    2 жыл бұрын

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    @scottelon2837

    2 жыл бұрын

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  • @scottelon2837

    @scottelon2837

    2 жыл бұрын

    @Caleb Luis it did the trick and I now got access to my account again. I am so happy:D Thank you so much, you really help me out :D

  • @calebluis2910

    @calebluis2910

    2 жыл бұрын

    @Scott Elon glad I could help =)

  • @rachellyman468
    @rachellyman4688 жыл бұрын

    this must have taken ages, but I am so grateful for it! it's difficult for me to pay attention to stuff like this, but the drawings made it very entertaining

  • @christaguevara7582
    @christaguevara75827 жыл бұрын

    As a biology student I found this really helpful. Thank you for posting it!

  • @shahirahsofea6261
    @shahirahsofea62614 жыл бұрын

    i've never ever written a comment on a youtube's video before. but this video totally helped me and it deserves all the recognition it can get. this video was so amazingly clear, fun to watch, understandable and just life saving. thank you so so much, love from Malaysia !

  • @dreamstar18
    @dreamstar189 жыл бұрын

    Wow I'm German and hadn't unterstand the Meselson and Stahl experiment til yet. I watched 10 german videos about Meselson and Stahl, but only THIS video has show me how it works! I thank you so much!! :)

  • @barracudacsgovideos9056

    @barracudacsgovideos9056

    9 жыл бұрын

    Indeed... :D

  • @Antonia-pj1jf

    @Antonia-pj1jf

    7 жыл бұрын

    Salmmor haha Same 😂

  • @mohammedsaqhibbilal1203

    @mohammedsaqhibbilal1203

    2 жыл бұрын

    How is being German related to better understanding of a molecular biology topic? Science is universal..nationality should hardly matter!

  • @susukiii4836

    @susukiii4836

    Жыл бұрын

    Omg ja einmal auf Englisch angeschaut und alles verstanden

  • @marinaromanova3475
    @marinaromanova34759 жыл бұрын

    The only Meselson and Stahl video on KZread that actually helped me. Two thumbs up!

  • @lillylindner8067
    @lillylindner80675 жыл бұрын

    This was amazing because you gave it so much context. My Biology teacher wasn‘t able to explain it in a logical way. 🙆🏻‍♀️ Now I‘m feeling well-prepared for my pre-exams. 👍🏼

  • @lyzabethhadynedwards2482
    @lyzabethhadynedwards24826 жыл бұрын

    This video was so so SO well done. Please continue on!!

  • @ryanandida8618
    @ryanandida86183 жыл бұрын

    I have never studied anything bio related before my first bio class in college. I was crazy nervous but these videos have helped me understand much better! Thank you so much !! :)

  • @diraaa99
    @diraaa996 жыл бұрын

    Brilliant! Was having a hard time understanding my Biology paper but this makes everything so clear! Thank you very much!

  • @nadinetaylor2449
    @nadinetaylor24496 жыл бұрын

    OMG I finally understand what my teachers were talking about! Thank U so much ☺

  • @Myron19
    @Myron197 жыл бұрын

    This is the best video on the internet for learning this. Thank you guys for the amazing video :)

  • @gabriellewilliams1048
    @gabriellewilliams10488 жыл бұрын

    this video is super good! definitely helped me understand this experiment A LOT more than i had before.

  • @orangesandlemons40
    @orangesandlemons406 жыл бұрын

    Thank you so much! It was hard to understand in class and in my textbook, but you explained it very well and now I understand it!

  • @jasmineyeh6693
    @jasmineyeh66936 жыл бұрын

    Thanks for this amazing video!! It makes it much more easy to understand

  • @perfecteducationhub5019
    @perfecteducationhub50197 жыл бұрын

    Fantastic!!! Your videos keep getting better and better... Thanks for this videos...

  • @navimumbaisatark
    @navimumbaisatark6 жыл бұрын

    It's awesome how it describes the process in such a interesting way and also the drawings are Soo good

  • @NirmalKumar-xw3ko
    @NirmalKumar-xw3ko6 жыл бұрын

    Yours is one of the most beautiful videos on this topic .

  • @Ibra4Soso
    @Ibra4Soso8 жыл бұрын

    simple, well explained, easy and clear sound , may Allah bless you for that !

  • @timmy18135

    @timmy18135

    4 жыл бұрын

    🕸🕷and may your good angel 👼 support you

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    @feedmewifi_477

    4 жыл бұрын

    Ibrahim Aldhoon inshallah

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    @Get2KnowJesus1

    3 жыл бұрын

    false god and idol. Jesus is the ONE true living God.

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    @rubydirks147

    3 жыл бұрын

    @@Get2KnowJesus1 this might be a shocker but there is more than one religion in the world!

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    @burrito7317

    3 жыл бұрын

    @@Get2KnowJesus1 stop shoving your religious beliefs into others, let people believe what they want to believe geez.

  • @kazkumail
    @kazkumail8 жыл бұрын

    Beautifully done, really helped!

  • @ayathassan123
    @ayathassan1239 жыл бұрын

    Just the video I was looking for!!!! Awesome!

  • @danicading1362
    @danicading13625 жыл бұрын

    This literally gonna help me on the bio test tomorrow. Thanks

  • @sarazafar3734
    @sarazafar37344 жыл бұрын

    This really helped clear my concepts. Thanks a lot

  • @ditamayo7095
    @ditamayo70956 жыл бұрын

    Great explanation!! LOVED IT

  • @zainabalalshaikh3249
    @zainabalalshaikh32498 жыл бұрын

    this was awesome plz don't stop making such type ved and thank you so much!

  • @lakshya8390
    @lakshya83904 жыл бұрын

    Super, wonderful, fantastic, amazing, mind-blowing, such a good creativity , explaining using diagrams makes students understand the concept easily and remembering quickly , tq so much, for this type of videos

  • @knithinmohan4293
    @knithinmohan42935 жыл бұрын

    Thank you, it helped me so much!

  • @tammamzouihed3371
    @tammamzouihed33715 жыл бұрын

    Whoever disliked the video has a mental problem ...seriously who In the damn world would dislike this amazing creation, it's perfect from the colours to the voice to the explanation .. everything in this video is perfect.. thank you soooo much ❤❤

  • @philippammer5671
    @philippammer56713 жыл бұрын

    Thank you so much! Very informative and understandable!

  • @dimamilli7516
    @dimamilli75163 жыл бұрын

    So useful😍 simple and clear thank you❤️

  • @aishwaryasinghal6374
    @aishwaryasinghal63747 жыл бұрын

    Thanks a lot for such informative content!

  • @freshlycleanedhands
    @freshlycleanedhands Жыл бұрын

    This is truly an amazing video. Thank you so much!

  • @deepjyotidas9163
    @deepjyotidas91632 жыл бұрын

    Your voice makes the video more understandable ❤️

  • @ghinaraji
    @ghinaraji8 ай бұрын

    Beautifully explained!

  • @vineelavudata421
    @vineelavudata4215 жыл бұрын

    Thank u for d video.. It was so simple and clear.

  • @anupamagoswami
    @anupamagoswami9 жыл бұрын

    Very educative, thank you very much. My semester just got saved!

  • @timothyso9781

    @timothyso9781

    8 жыл бұрын

    +Anant Goswami I feel your pain. School is tough.

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    @anupamagoswami

    8 жыл бұрын

    I'm in college bru!

  • @timothyso9781

    @timothyso9781

    8 жыл бұрын

    Anant Goswami oh boy

  • @70RISHIKESHAVANS
    @70RISHIKESHAVANS4 жыл бұрын

    The best video in KZread Hats off for you sir.

  • @isaacppailay8332
    @isaacppailay83326 жыл бұрын

    This lesson is quite amazing, am glad that I finally understand DNA replication

  • @wasanthikaathukorala6812
    @wasanthikaathukorala68127 ай бұрын

    This is such a logical explanation. Easy to understand. Thanks a bunch ❤

  • @Chelsea-cd5lf
    @Chelsea-cd5lf4 жыл бұрын

    thank you so much this was so easy to understand!! 😭😭👍👍

  • @madelynlewis3842
    @madelynlewis38423 жыл бұрын

    this video is sooo good thank you!!

  • @ilyassalmon9513
    @ilyassalmon95132 жыл бұрын

    Thank you for posting it!

  • @Ta3allamOnline
    @Ta3allamOnline6 жыл бұрын

    Amazing video.

  • @kimiazare1884
    @kimiazare18845 жыл бұрын

    I loved it even for the international student was so easy to understand

  • @harish834
    @harish8342 жыл бұрын

    Thank you So much. It is Simple,Intresting to understand the concept.

  • @iriscardoso1044
    @iriscardoso10449 ай бұрын

    OMGG!!!! THANK YOU SO MUCH!!! This was so helpful!!

  • @KnockoutEcho
    @KnockoutEcho Жыл бұрын

    thank you! this video helped a lot

  • @SteadfastWorshipper577
    @SteadfastWorshipper5776 жыл бұрын

    Thank you for this thorough and clear explanation of Meselson's and Stahl's experiment.

  • @gregoryyang8988
    @gregoryyang89883 жыл бұрын

    Very nice explanation.

  • @Skittlezs710
    @Skittlezs7108 жыл бұрын

    Actually, everyone gives Watson and Crick all the credit for discoverying DNA Structure buuuuuutttt, Rosalind Franklin was the one to discover this, for she spent so much time using X-Rays in order to figure out the DNA structure, which caused her Cancer. While she was sick battling cancer, two other students researching DNA Structure in the same University( WATSON AND CRICK) sneaked into her Dorm room and stole all her notes AND Published them taking all credit and A Nobel Prize for it But Rosalind Franklin died of cancer before she could take back all recognition of her Research.

  • @DanielLieu

    @DanielLieu

    8 жыл бұрын

    +Adlin Hernandez I like how you talked about Rosalind Franklin! She was actually a huge part in the discovery of DNA because of the X-Ray diffraction she was able to obtain. It was critical in understanding that DNA spiraled in a double helix. Unfortunately, due to the reputation of women in science, her work wasn't really respected and neither was herself as a scientist in general. Unfortunate that her death occurred before the Nobel Prize because I believe she would have made a huge impact in the stigma that women scientists aren't as great as men -- which even exists today as women get paid less :) Hopefully that can change!

  • @rohanshetty5103

    @rohanshetty5103

    8 жыл бұрын

    is it true ..? i mean i never heard of it before !

  • @DarwiiNs

    @DarwiiNs

    7 жыл бұрын

    yea she basically told them everything they wrote about

  • @teresataylor-whiteley823

    @teresataylor-whiteley823

    7 жыл бұрын

    This is not strictly true. Yes Rosalind Franklin was an X-Ray Crystallographer at Kings College London were work was undertaken to determine the crystal structure of DNA (along with the scientist Maurice Wilkins) , the data of which Watson and Crick used to describe the structure of DNA in their publication 'The Double Helix'. However, Watson and Crick were working at a laboratory at Cambridge, not Kings College London and neither of them were students, they were all research scientists working in different laboratory groups. In 1956, three years after Watson and Crick had published their model, Franklin was diagnosed with ovarian cancer, which exposure to x-rays has been suggested to be a possible factor in her illness although other members of her family had previously died of cancer.Nonetheless, Franklin's work was crucial to the development of Watson and Crick's model and she definitely should have received recognition.

  • @jemmaxoxo9229

    @jemmaxoxo9229

    6 жыл бұрын

    TRUTH she died because of her research and work

  • @alishashashasha6909
    @alishashashasha69092 жыл бұрын

    Tysm for this video 💜

  • @mrinavaition
    @mrinavaition3 жыл бұрын

    Easy to understand and fun to watch too

  • @SBShuTingTeo
    @SBShuTingTeo4 жыл бұрын

    Very useful to me,thank you!

  • @valentinaescalona8914
    @valentinaescalona89147 жыл бұрын

    Muchas gracias ♥

  • @smorgi
    @smorgi9 жыл бұрын

    Thank you... I understand!!

  • @surajdewalkar9127
    @surajdewalkar91277 жыл бұрын

    so nicely explaned...thnks

  • @rockycreation2342
    @rockycreation23423 жыл бұрын

    Wow .....‼️‼️‼️‼️ excellent explanation

  • @ayano_sensei
    @ayano_sensei2 жыл бұрын

    Thanks now the concept is crystal clear😊😊😊

  • @subrat2021
    @subrat202110 жыл бұрын

    Amazing. Very very damn helpful.

  • @malaikatanveer1406
    @malaikatanveer14063 жыл бұрын

    Beautiful video

  • @Ash-zb7bu
    @Ash-zb7bu4 жыл бұрын

    thank you so much! this saved me.

  • @biology_com
    @biology_com3 жыл бұрын

    Very well explained

  • @theperplexchild2078
    @theperplexchild20783 жыл бұрын

    thank you for this really helped me

  • @theinsomniac8792
    @theinsomniac87923 жыл бұрын

    wheenever i watch ur videos your writing is so satisyying

  • @pandeydivyjyoti
    @pandeydivyjyoti6 жыл бұрын

    Very helpful 😊

  • @aminakm3503
    @aminakm35036 жыл бұрын

    excellent presentation👍👍

  • @rojapa2402
    @rojapa24024 жыл бұрын

    Nice clarification information 👍

  • @lynngedankenwelt9947
    @lynngedankenwelt99476 жыл бұрын

    Thankssssss. The german yt videos were as complicated as my biology book, but this Video was easy to understand You saved my life xD

  • @hollowghost2
    @hollowghost29 жыл бұрын

    Perfect video.

  • @Godinus.
    @Godinus.2 жыл бұрын

    This is the most beautiful way to explain,the most beautiful experiment in the history of biology.

  • @YourekaScience

    @YourekaScience

    2 жыл бұрын

    Thank you! So glad you like it :)

  • @iraqi3612
    @iraqi36122 жыл бұрын

    Thank you very much doctor

  • @ajinkyakarade8068
    @ajinkyakarade80688 жыл бұрын

    woww wowww woowwww... this video is superb as u gave us the information from the beginning :D

  • @aparnatalukdardas584
    @aparnatalukdardas5842 жыл бұрын

    Really thanks a lot! It was explained so nicely that after watching many videos I finally understood because of this!!!!

  • @user-tf9zh2jh6w
    @user-tf9zh2jh6w9 ай бұрын

    This is really good

  • @ahmedmadhy842
    @ahmedmadhy8423 жыл бұрын

    Very clear

  • @lydilein346
    @lydilein3466 жыл бұрын

    You explaind it soo well that I can unterstand it even if I am german

  • @DeepakKumar-dg9wn
    @DeepakKumar-dg9wn4 жыл бұрын

    Niche wali line ki vajhe se nhi dikh reha hai

  • @mirzaahmadsaeedbaig5798
    @mirzaahmadsaeedbaig57987 жыл бұрын

    can u explain beadle and tautum experiment

  • @yellowbelliedslider6719
    @yellowbelliedslider67197 жыл бұрын

    Well done! ^.^

  • @ukaszsurzycki845
    @ukaszsurzycki8455 жыл бұрын

    really beautifull idea....

  • @jueedhar5449
    @jueedhar54494 жыл бұрын

    Beautiful .

  • @AyeshaKhan-gp9on
    @AyeshaKhan-gp9on7 жыл бұрын

    You deserve more subs

  • @dangthatscool1
    @dangthatscool19 жыл бұрын

    Good work, here!

  • @tyneciadavis408
    @tyneciadavis4083 жыл бұрын

    wow i have a bio final for college tommorrrow and you helped so muc

  • @YourekaScience

    @YourekaScience

    3 жыл бұрын

    You're very welcome!

  • @libs8709
    @libs87097 жыл бұрын

    This video is so so helpful, I'm definitely a visual learner

  • @Eerisey17

    @Eerisey17

    7 жыл бұрын

    same!

  • @ARedVelvetBunnie

    @ARedVelvetBunnie

    7 жыл бұрын

    English Rose me too

  • @zafariqbal2183
    @zafariqbal21837 жыл бұрын

    superb!

  • @carlymain8391
    @carlymain83916 жыл бұрын

    thank you!

  • @janlauterbach4696
    @janlauterbach46965 жыл бұрын

    It is indeed a very elegant experiment

  • @priyal5873
    @priyal58733 жыл бұрын

    THANK YOU

  • @theinsomniac8792
    @theinsomniac87923 жыл бұрын

    i need those markers

  • @jcn268
    @jcn2682 жыл бұрын

    so is n15 old and n14 new?

  • @jozhx.
    @jozhx.9 жыл бұрын

    thank you so much bless you

  • @randomname5118
    @randomname51185 ай бұрын

    Even if english isn't my first languaje you managed to explain it better than other videos in spanish (first languaje) congrats

  • @abeeranasir324
    @abeeranasir3243 жыл бұрын

    Outstanding effort👌👌

  • @YourekaScience

    @YourekaScience

    3 жыл бұрын

    Thanks a lot 😊

  • @afifaamjed2294
    @afifaamjed22946 жыл бұрын

    AMAZING EXPLANATION!!! I finally understand this yayayaya :D one question though: what if the bacteria were allowed to replicate a third time in N-14?

  • @charlieshin9868

    @charlieshin9868

    6 жыл бұрын

    Afifa Amjed it would depend on which strand was getting replicated i think. So if it was the light strand it would just come out as 2 light strands. But if it was the hald half strand it would come up with 1 strand that is light and 1 strand that is half half

  • @afifaamjed2294

    @afifaamjed2294

    6 жыл бұрын

    www.thestudentroom.co.uk/attachment.php?attachmentid=698336&stc=1&d=1508899096 This is the picture in my textbook. I don't get the results of the 3rd generation with N-14 (test tube 4).

  • @schoolokara7528
    @schoolokara75283 жыл бұрын

    wow... it is really good...

  • @pb5631
    @pb56313 жыл бұрын

    Awesome n best n beautiful vedio ever watched

  • @YourekaScience

    @YourekaScience

    3 жыл бұрын

    Thank you so much 😀

  • @sportscook
    @sportscook9 жыл бұрын

    really awsome vids

  • @divyanshu6519
    @divyanshu6519 Жыл бұрын

    Ceasium chloride density gradient was used to separate.

  • @masud4491
    @masud44912 жыл бұрын

    You should add time stamps it will be more convenient for us 😉 . 👏 Amazing video

  • @YourekaScience

    @YourekaScience

    2 жыл бұрын

    Thanks for the tip!

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