My earphones get tangled all the time, but miles and miles of DNA don't. Mind blowing.

@vjlove1218

5 жыл бұрын

Stan Lem yes! But DNA has a LOT of help from many different proteins

@its_tomothy

5 жыл бұрын

For some reason, I read that as "My earlobes get tangled all the time" :0

@lalaithan

5 жыл бұрын

@@its_tomothy do your ears hang low? Do they wobble to and fro?

@its_tomothy

5 жыл бұрын

@@lalaithan yeah, im actually dobby the house elf lol

@ddbrayen1aramai1tii

5 жыл бұрын

Its actually tangled and become 3D coumpound

11 years later, the video still better than a two hour lecture

"why is a teenage boy similar to helicase? they both want to unzip your genes (grins)" I'm speechless

Hank: "Hey you wanna make one?" Me: I'm 12

This dude is getting me through college one video at a time.

@lilzod4862

4 жыл бұрын

College?!? Bruh what kind of college you in?

@zoefoster6750

4 жыл бұрын

I was gonna say, I’m learning this in Level 2 biology here. (I’m 15, in a 16 year old class)

Editing team: "Hank please hold up a shoelace and be amazed by it"

@rishinixon7560

4 жыл бұрын

ha!

Good Luck on your test/exam/final/quiz tommorow that we both know you are just now studying for... éxpöšêď ;)

@georgiaalexandriaa

5 жыл бұрын

it's actually today

@kyleharvey3824

5 жыл бұрын

100 percent facts

@EarlyOwOwl

5 жыл бұрын

Thanks fren

@hxhchimeraantarc2268

5 жыл бұрын

Exposed

@jays9572

5 жыл бұрын

i feel very ,much attacked

Thank you so much for covering Rosalind Franklin, some of my previous instructors only briefly mention her and they rarely discuss her major contributions to the discovery of the DNA structure.

its crazy how a youtube channel that i get for free is a better teacher than the teacher i paid hundreds of dollars for. goddamn the college life.

@ebkdoa3535

6 жыл бұрын

Tell that to the people who will be paying money to watch this in a couple months

@mycaroxas4088

5 жыл бұрын

Paid with ads my friend. and yet, I love Crash Course!!!!

@BannerOfBlasfemy

5 жыл бұрын

college should be free

@bluon259

5 жыл бұрын

BannerOfBlasfemy college is free for me at least, all I had to do was write a paper and take a test. (I’m a freshman in high school). It all depends on where you live and where you look, and whether or not the opportunity is there yet. But yeah, people should go to college for free if they have the drive for it.

@sourcetext

5 жыл бұрын

College is a for profit business. The ancient Greeks called them Sophists

this 12 minute video basically goes over eveything we've learnt in pre-ap bio's dna unit, which took 2 weeks for us. Thank you Hank

@Epicgamerbro2000

8 жыл бұрын

He explained t better than my lazy ass teaxher

@Angelicmey

8 жыл бұрын

+suraj bhat same

@djmoneystacks3600

8 жыл бұрын

+Dale are you mad😁😁😄

@jeremytownsend6805

8 жыл бұрын

+Dale Some teachers can't have class lectures and this is more interesting than reading a chapter in a textbook.

@wizardvenom8500

8 жыл бұрын

+Dale You can't even speak English lol

When Hank said "POP QUIZ!" my heart started racing so fast.

I started teaching biology in 1993 and I KNOW my kids (now middle aged) KNOW it was Rosalind Franklin who did the work. Hank, thank you. I left teaching, but am thinking about getting back into the classroom. Using your videos to study up for the test to get recertified. :)

@toshido_yamada

5 жыл бұрын

Gl, i hope you get re certified

@purplegypsylady777

4 жыл бұрын

Please.. The world needs good teachers!!

Usually when I watch videos to catch up on material idk the night before an exam I watch it in 1.5 speed but these crash course videos are the only ones I actually have to watch in like .5 speed omg

@med8615

7 жыл бұрын

working with 2x speed over here, gl.

@jettlaxholly

6 жыл бұрын

mariaarakal lol I’m usually at 1.25 speed with home because he already talks fast, but I have no time to waste

@rachelelizabeth6017

6 жыл бұрын

jett lax same! I always have mine at 1.25 or 1.5 speed! 😄😄😄

Trying not to fail my bio final. This is so helpful, and I want to thank the Green brothers for starting the channel, and the whole CC team for making it a reality. You guys are kind of the best.

@yelectric1893

6 жыл бұрын

Good luck

@beckylieb2637

6 жыл бұрын

awesome idea and dedication indeed... but they have some financing... bet they would be shut down if they taught some of the truth in science and history. ....

HANK: Hey you wanna make one Subtitles says :oh dear god *Squeak**squeak*

@cyberxxxcyberxxx9464

4 жыл бұрын

I like the adult jokes on this episode😁😅

@katieniwa7961

4 жыл бұрын

I don't understand the joke...

@PersimmonHurmo

4 жыл бұрын

@@katieniwa7961 you're too young, get off the adult internet

@TheHappyHummy

4 жыл бұрын

His name is hank...

@joestar8112

4 жыл бұрын

Oh my oh my

anyone find it weird to think about how when this video was first released it probably got like 20,000 views but then over so many years millions of students watched it

Anyone else cramming the day before the exam?

@mariadedios9081

8 жыл бұрын

+KatieSings&Things ME!

@catherinec3735

8 жыл бұрын

+KatieSings&Things I'm glad im not alone XD

@arwahasnain5624

8 жыл бұрын

This is the time Crash Course's views exponentially increase the most

@darkdestiny3700

8 жыл бұрын

maybe...

@shingaikagunda6426

8 жыл бұрын

Meeeee!!!! Lol

When he said "Pop Quiz", my heart jumped. Sadly, I'm used to my science teacher saying that.

@alicemeliksetian7981

4 жыл бұрын

Matthew Villalba - Mutis thats what happened to me when he said “ *hey, you wanna make one* ”

The funny part about biology is that everyone pronounces everything differently

I love how the captions say "Hank why" when he told the helicase joke.

During the diagram from 3:00 to 3:40 all of the carbons that you circle and label are 5' carbons. The 3' carbon is the carbon that the phosphate group bonds to on the next nucleotide. So on the left stand the 3' carbon of the bottom sugar would be the very bottom left carbon with the two atoms (hydroxyl group) hanging off of it, and the corresponding carbon in each subsequent sugar.

Kudos for giving Rosalind Franklin the credit she deserves!

@laurasutherland2352

6 жыл бұрын

Kinda bothered me that he didn't mention that women scientists tend to be disregarded for the sole fact of their being female. Still, love me some Hank Green.

@pastsubstance2930

6 жыл бұрын

It's pretty sad that that is a controversial topic to even discuss about.

@victorfergn

5 жыл бұрын

hmm the info is wrong, it wasn't Franklin who shared the info (she didn't like sharing anything, she even disliked when other people got into her lab) the one who shared the info was Wilkins, he showed the picture of the double helix to Watson; Franklin got furious about that (Wilkins and Franklin hated each other) Besides... she was far from theorizing how DNA worked, it was Watson how figured it out. Obviously Franklin had a key role but she wasn't Emmy Noether.

@pastsubstance2930

5 жыл бұрын

Just another Bird no not everyone. Probably the people you know and where you come from highlights Rosalind’s scientific feat but not every country.

I don't remember Crash Course being this complicated when I was in 9th grade biology, though I guess I should be thankful that 6 years later it is still helpful for my college level genetics class.

my science teacher played this in class and when it got to the joke omg I'm screaming

I wish he is my anatomy teacher, I would get A so easily. my anatomy final is tomorrow and your videos help me in not wanting to read half a textbook

@KitKatKool99

8 жыл бұрын

SamE AND I SEE CHANYEOL

@alhassan5623

8 жыл бұрын

+Zsófi Szabó I passed my test yay!!! I can watch exo videos all now

@humixmusic4lyf

8 жыл бұрын

+pcy_exo2 congrats! ^u^

@alhassan5623

8 жыл бұрын

+humixmusic4lyf thank u!!^^

@whenidieburymewithapenguin3136

8 жыл бұрын

I see my bias in you profile pic :3 Congrats on passing btw X"D

Thank you for translating my textbook into understandable English terms. I love you

5:28 "See how that works? It's not super complicated" yEaH oKaY

@coconutsharksinthewater4728

4 жыл бұрын

same i didn't get it at all xD

Who’s here cramming before a test in 2019 lol

@ryna2502

5 жыл бұрын

y’all doing the AP test?

@aarishhanif1837

5 жыл бұрын

Yep

@daciannabel9076

5 жыл бұрын

Me😂

@dearielbell663

5 жыл бұрын

Me I have the biology staar tomorrow 😔😭

@gomamon15

5 жыл бұрын

Me right now for a final. Not that i wanted to cram but I have job and other classes, so here i am... tons of luck everyone

I'm glad he included that Rosalind Franklin contributed to the findings of the DNA structure not until this year after my bio teacher told us about Rosalind Franklin have i found out that it wasn't all just Watson and Crick. I have lost lots of respect for Watson and Crick after that day.

@Wolfeywolf16

9 жыл бұрын

It angers me to see how discredited she was

@ohkaryukai

9 жыл бұрын

Taylor Clay they literally stole her work. you'd be surprised at how often men are credited for things women did. Ava Lovelace, Sanora Babb, Lise Meitner, Cecilia Payne, Hedy Lamarr, Vera Rubin. It's pretty awful.

@nexusmares3371

9 жыл бұрын

harumi Well let's not get carried away. "You'd be surprised at how often men are credited for things women did." Making statements like that perpetuate sexism. It's not like men everywhere have declared war on women and are out to steal their work. What if Watson and Crick had been women? It should stay a "x" stole from "y" issue, which is what it really is, not a man stole from woman issue.

@ohkaryukai

9 жыл бұрын

Ella Blun preach.

@ohkaryukai

9 жыл бұрын

Vinicius Fernades i suggest reading a few of her biographies if you'd like to learn more =) she was pretty rad in real life.

Was having trouble remembering all the steps of the lagging strand but now remembering it for being a scumbag strand makes it so much easier

@rafaelcontreras4358

5 жыл бұрын

Jiji meAmeliacontreras

@rafaelcontreras4358

5 жыл бұрын

Creo ieuyfieyeutdy

minute 3:07-3:42 has an error. The 5' is correctly highlighted but the 3 ' is wrongly highlighted.

@ryankruskamp8973

5 жыл бұрын

Thank you! It wasn't making sense so I checked the comments to make sure.

@hifrax

4 жыл бұрын

and i think the 10:57 part has an error as well. doesn't the lagging strand go in 5'-3' direction?

@Jaspertt1

4 жыл бұрын

@@hifrax yeah i think so as well. I think what they meant is that the lagging strand goes into the 5'-3' direction which would mean the DNA polymerase won't work 'efficienly' since it cannot go in the opposite 3'-5' direction

@abdallab8511

4 жыл бұрын

Yess i am checking the comments to make sure

@gretchendean7346

4 жыл бұрын

@@ryankruskamp8973 great that folks who caught that commented. Comments RULE!

I found myself in here when I feel hard to understand a subject in biology. Than, BOOM. It feels helixciting.

"Hey... you wanna make one?" -Hank, 2012

@sarah45532

9 жыл бұрын

I laughed so hard xD

@hi-lo1jm

7 жыл бұрын

"(oh dear god)" -The subtitles, 2012

@anjalimishra6470

7 жыл бұрын

[when talking about teenage boys and helices both unzipping genes] Hank why- The subtitles

@evyuwu4509

6 жыл бұрын

PlatinumLuxray freaking creepy, we’re currently watching this is science class.

Oh behalf of my dog who just watched this, he says he 'is most certainly not a human and did not care for the accusation'. I'm afraid he has unsubscribed

@LuisSierra42

8 жыл бұрын

My cat had a similar reaction

@shyamalsingaravelu92

8 жыл бұрын

tell your dog hes taken drugs to be able to even understand this

@JackT13

8 жыл бұрын

Shyamal Singaravelu he just said 'ketamine is a wonderful thing'

@johnbradford6875

7 жыл бұрын

I was put on ketamine after a had several surgeries within a month (they were worried about the amount of opioids I had been on, and the amount needed to control pain straight after surgery having a shoulder replacement might kill me post-op). I beseech the medico's out there, be it G.Ps, surgeon, nurses etc, to give patients the heads up about ketamine BEFORE the surgery - I came out of surgery, woke in the recovery room, and thought I was in a cartoon - everyone looked like something between a Disney character and Avataar (did I spell that right?). I would have panicked, except I was too smashed. I asked if I was hallucinating, and some guy I assume to be the anaesthetist said "no," that's the ketamine," - if this wasn't hallucinating, I need a new definition. I was in a lot of pain, but it was someone else's pain, if that makes sense (if you were on ketamine it might - it's called a "dissociative state", IMT). Very trippy. Wonder if animals have this happen?

@JackT13

7 жыл бұрын

+John Bradford you are a cartoon. Or at least your user icon suggests such

0:45 turn on subtitles, will not disappoint you I swear

I love Hank Green, his videos are so funny. I honestly don't care what he talking about, it is just sooooooooooo interesting.

"How is a teenage boy like the enzyme Helicase? They both want to unzip your genes" Oh boy...

@ThingsUShouldLike

6 жыл бұрын

My teacher showed this video in class and literally muted that part 😂😂😂 I got curious to what he said so I’m here now...

@stefanli1755

5 жыл бұрын

YEESSSSSS!!!!!

@kikialeaki1850

5 жыл бұрын

Oh helicase

Crash Course is one of the best things to be on youtube, its fun to watch educational and overall helpful. You guys have proven that knowledge is power in so many ways, breaking down complex subjects while maintaining a high energy level teaching process which does not leave a student sleeping. You guys are like the Bill Nye of our time, keep up the good work. Its really pathetic that more people don't know about your work, grade schools should promote your program, but then again they are more focused on their sports teams, but overall for all of us non-athletic people you guys are champs.

For the first time in my two years in college, I actually understand what I am seeing. Thank you. I am in the MLT program trying to understand how PCR testing works but in order to do that I realized that I REALLY need to comprehend DNA and how it is made in order to understand how it is taken apart and analyzed. You have really given me a strong visual and I can't thank you enough.

I remember watching this video for exams in middle school and high school. Now I'm in college, and I'm here once again :(

Good luck tomorrow everyone!

@jennanicole6354

5 жыл бұрын

JKay5phD exposed

@AndrejNikolov-xw2gi

5 жыл бұрын

Thanks man! :)

@l3mi11ion

5 жыл бұрын

JKay5phD thanks bro!

@VikasYadav-to1xr

5 жыл бұрын

Thanks:)

@ainsley5563

5 жыл бұрын

lmaooo

I cried about how informational this is.

Hank. You are a blessing to every student in the world. Reading and digesting a convoluted and confusing textbook is so much easier after getting a grasp on the general idea first from watching these videos. Thank you so much!

Who is watching this before the AP Biology test? Mine is next Monday fml

@ChiNguyen-mp5kd

5 жыл бұрын

Haha me too but im happy with an 1 😂

@carlie3628

5 жыл бұрын

Same

@anselcheesecake419

5 жыл бұрын

@@carlie3628 same

@giannagowe8486

5 жыл бұрын

My cape Unit 1 is tomorrow

@realgrieve

4 жыл бұрын

Yuh bug mine is first day of school

This video was perfect for helping me procrastinate on studying for my biology exam. Thanks Hank!

phrase the lord for youtube teachers. Why waste your time reading long ass textbooks and still end up confused when you can just watch a bunch of these videos. These are so much cooler and so much less boring

@bananimal45

9 жыл бұрын

"the lord is...uh...the lord." ...ohhhhh you meant PRAISE the lord.

@fmar105

9 жыл бұрын

Jennifer Li I disagree. A textbook will give you a much more in-depth view of such mechanisms than a ten minute video, and will leave you with a much better understanding. I find my textbook challenging and interesting. These videos are great, but they are mere supplements to textbooks and the like.

"hey, you wanna make one?(oh dear god)" lol

Although I only watched half of it and only understood a few parts, the laying out of it combined with my other revision resources finally helped me get the gist of it - you are a star, thank you!

does anyone else find it creepy that this happens in ur eyes. like its happening right now and you dont see it.

@jonathanmusemeche4865

8 жыл бұрын

+blo shit up Your pupil is just open space covered by the cornea, a multicellular tissue that contains no blood vessels, that's why you don't see it occurring. The nerves behind it detect light and then your brain makes sense of those indications. Not to mention that cells are microscopic and the nucleus is inside of the cell and chromosomes are inside of the nuclear membrane of the nucleus and so on... So then you might ask well how do those cells stay alive without oxygen? Because all eukaryotic animal cells need oxygen for respiration to utilize energy and there are no blood vessels to provide the oxygen. The cornea diffuses oxygen from the tears secreted by your tear ducts.

@reshmi5333

8 жыл бұрын

+blo shit up hi !! fellow kpopper !! nice to meet a kpopper here

@Simplebeez

8 жыл бұрын

+blo shit up High Skool!

@satan4606

8 жыл бұрын

i see it

@squiddi1393

8 жыл бұрын

+blo shit up You're totally incorrect. First off, the cells in your eye don't actively divide. They are with you your whole life. They are constantly in the G0 phase therefore DNA replication doesn't occur in them and so you wouldn't see this anyways. Replication only happens in preparation for mitosis in interphase, like when you grow as a child or your cells divide and repair your body when you get a cut on your skin, otherwise cells refrain from dividing hence they don't replicate DNA.

*CRASH COURSE* _Video notes_ Every body-cell (somatic cell) has 46 chromosomes each containing one DNA molecule *DNA-* Nucleic acid (and so RNA) Double helix *Nucleic acids are polymers* -Many small reprating molecular units -In DNA, these small units are called nucleotides -Put them together and you have a polynucleotide *Nucleotide* -5 Carbon sugar molecule (deoxyribose) -Phosphate group 1- of 4 Nitrogenous base -Adenine (A) -Thymine (T) -Cytosine (C) -Guanine (G) -In DNA sugats and phosphates bond together to form twin backbones Phosphodiester bond -The two strands are anti-parallel -One side goes from 5' ---> 3' -The other from 3' ---> 5' -*5' - AGGTCCG - 3'* -*3' - TCCAGGC - 5'* -These two long chains are linked by the nitrogenous bases via relatively weak hydrogen bonds *Ex:* A-T are hold by a hydrogen bond *Base pairs* -A-T (2 hydrogen bonds) -G-C (3 hydrogen bonds) -Therefore G-C is stronger because it has one more hydrogen bond It is the order or the "Base sequence" that allows your DNA to create you. -*AGGTCCATG* means something completely different as a base p air sequence than, say, *TTCAGTCG* *RNA* *(3 MAJOR DIFFERENCES)* *1.* Single-stranded molecule (nod ouble helix *2.* Sugar in RNA is ribose, which has one more oxygen atom than deoxyribosome *3.* RNA does not contain Thymine (T) instead has Uracil (U) *DNA discovered by Swiss biologist* Friedrich Miescher *Rosalind franklin* X-ray diffraction *Replication* *Helicase*- Enzime Unzips that unwinds the double helix bybreaking hydrogen bonds *DNA Polymerase* -Adds matching nucleotides onto the main stem all the wat down the molecule -Needs a primer, the primer hooks on to so it can start building the new DNA chain -RNA primase provides the primer -The leading strand only needs this RNA primer once at the very beginning -Then DNA polymerase is all, "I got this" and just follows the unzipping adding new nucleotided to the new chain continuously -DNA polymerase can pnly copy strands in the 5' to 3' direction -So there is a problem... the lagging strand is 3' to 5' -RNA primase lays down short RNA primers that gives the DNA polymerase a starting point to then work backwards -Short segments -DNA polymerase can proofread removing nucleotides from the end of a strand when they discover a mismatched base *Okazaki fragments* -RNA primer -These allow the strands to be synthesized in short bursts -And then another DNA polymerase has to go back over and replace all those RNA primers *DNA Ligase* -All of the little fragments get joined up by a final enzyme called DNA Ligase

@Ps3COD4Fan

10 жыл бұрын

*I've created a set of study flashcards for DNA replication and much more, feel free to check it out, and please thumbs this up so others can use this resource! Study on!* *GO BIOLOGY!* quizlet.com/42951455/bild-1-chapter-13-molecular-basis-of-inheritance-dna-replication-2-flash-cards/

@Ps3COD4Fan

9 жыл бұрын

***** You don't have to, but they helped me pass University level Biology.

@dogdemon62

9 жыл бұрын

I just wanted to say I love you. I'm currently taking Bio I and it sucks.

@Ps3COD4Fan

9 жыл бұрын

dogdemon62 Thank you, but you should change your views about biology or you will never enjoy the subject. If you are able to "like" or be intrigued about biology, you will end up enjoying it and understand it a lot better. Your mood towards a subject is really important.

@dogdemon62

9 жыл бұрын

I do like biology, it's just the cells are kind of a difficult concept for me to grasp. I love looking at organisms as a whole, and I understand the organ systems very easily, it's just cells I don't get lol. I lean more towards anatomy and physiology.

To Hank and everyone at Crash Course who helps in creating these videos. I just want to thank you so much on behalf of all of the panicking people who have trouble remembering all of this information. These videos are absolutely incredible! Keep doing what you're doing! :)

Their videos have come so far since 2012, from the content to the animation graphics, looking back he is so young and derpy! And here we are, 11 years later he is still saving my butt, from highschool all the way to finishing college. Thank you Hank Green and the team, for helping us get through school in a fun and enjoyable way!

"Hey. You wanna make one?" I'm eleven.... My god....

@arabeasy

9 жыл бұрын

Lololololololololololollolololololoollolllloolol

@TheSpicySimon

9 жыл бұрын

"Hey, you wanna make one?" "Im a guy." "My god"

@gregjang5402

9 жыл бұрын

So am I.

@rexyboi466

9 жыл бұрын

So am i

@gregjang5402

9 жыл бұрын

School homework.

On 3:35 there's a mistake in the sketch. The 3' carbon is indicated on the 5' carbon, instead of the 3'

@esmeraldacuriel4618

8 жыл бұрын

+Maria Nascimento yes i was so confused about that

@natattacc99

8 жыл бұрын

So...which side is 5' and which side is 3'?

@coenijn

8 жыл бұрын

+NH.-B Well the 5'-prime end was shown correctly both times, the 3'-prime end however is located at the third C-atom. In the video both the 5'-end and the 3'-end are indicated at the 5'-end. If you take the left strand (the side of the purple ribbon) of nucleotides you'll find that the 3'-end of deoxyribose is located at the lower left corner of said molecule. Since the saccharides are shown in a Haworth projection it's quite difficult to point out. Here's a not very good Fischer projection of deoxyribose I made pointing it out. Remember, this is the same molecule as shown in the clip, just a different style of drawing it. HOC-CH2-CHOH(this C-atom is the 3'-end)-CHOH-CH2OH(and this is the 5'-end). In an aqueous solution (almost) all monosaccharides (such as deoxyribose) will form to become a circular structure, such as shown in the video.

@nureileendeannakamaruizam3961

8 жыл бұрын

+NH.-B bealbio.wikispaces.com/file/view/dsDNA.jpg/166732981/350x272/dsDNA.jpg

@natattacc99

8 жыл бұрын

+nureileen deanna kamaruizam Thanks :)

"it's double helix-citing" i love these dorky puns

Thank you so much crash course...you guys are lifesavers and explain so much from scratch in such less time...love the animation. Pl keep helping us never stop creating

"How is a teenage boy like the enzyme helicase? They both wanna unzip your genes" oh my lord i have not stopped laughing

Keys to being successful as a Pre-Med major: 1) Procrastinate all semester 2) DON'T read any of the assigned material 3) Watch every CrashCourse video the night before an exam 4) Walk into class confidently knowing that you prepared well for the exam

@sumiatheangel9397

8 жыл бұрын

+kayeamele step 5: panic as you forget half the names of the muscles and bones you supposedly learned the previous year.

Shoutout to Hank for teaching me before my biology test IN LITERALLY 5 HOURS

Just think how far CrashCourse has come now! Thank you CC and Green brothers for helping me get through my exams

my teacher skipped the part where he joked about unzipping jeans so I looked this up to fond out why XD

@wizardvenom8500

8 жыл бұрын

+Darby Jones seriously? haha. What year group are you in? It's hardly inappropriate lol

@Dstewar25

8 жыл бұрын

9th and I know right lol.

@adriennebatty3787

8 жыл бұрын

+Darby Jones Oh my gosh we were learning about this and I'm in an online school so I typed out the joke in the class and my teacher did NOT like it.....it was very awkward for me. I would have died if I was in an actual physical school. But we're in 10th grade, it's not that bad of a joke.

@inserthere7048

8 жыл бұрын

+Techman shit hide your meth the apocalypse is coming.....like me ;)

@tiglathpilesariii

8 жыл бұрын

+Darby Jones Me too xD

..this channel is the ONLY reason why im getting a good grade in my science class

Props to whoever did the subtitles for this episode, they're hilarious! 😂🤣

This is SO good for studying for the TEAS exam. It’s quick n he touches on all the important factors of dna while being a lil nerdy funny..🙏🏽

I start watching this so I understand my class better, and I end up realizing it's happening ALL THE TIME in my body, so cool!

The freaking jingle. One of the 1874959 reason why I love crashcourse

These are fantastic. Thank you for the uploads! I hope you guys bring back more science episodes

Watching this again. Hank is a great teacher! Thanks for everyone who helped make this

Everyone who studies Biology should watch this.

Only a very small number of people here will understand this, but... The way I remember what Okazaki fragments are is this--the two strands are only gonna be together a short time before they're separated permanently.

@totheblueberry

9 жыл бұрын

AHHHH! THE FEELS! THE FEELS! I was actually going to make a comment about Okazaki hahaha

@theghostofspookwagen4715

9 жыл бұрын

Glad to be of service.

@totheblueberry

9 жыл бұрын

Ahh, stop it! I'm gonna start crying when I'm taking my Bio Exam tomorrow! :O

@iloveu975

9 жыл бұрын

I don't get it! Please let me in on the joke lol

@theghostofspookwagen4715

9 жыл бұрын

It should be noted that, in a similar fashion, both of the Okazakis who discovered those fragments suffered a similar fate. However, it was the husband who died and not the wife, and he died of a disease.

years of trying to understand this from many different professors broken down into only 12 minutes brilliant.

Hank Green: "Hey, wanna make one" Me "Ok, I'm out!"

That helicase joke omfg

@Imogene512

10 жыл бұрын

I will never forget what helicase means now haha!

This really helped me as I have the EOC in a day!

this guy has brought me though all my school years, i cannot thank him enough!!

This video was really helpful for me to comprehend DNA and its replication process. I will dare to say that it is the best video I have ever watched about this context on KZread. Thank you!

The joke Hank makes in the video at 9:25 made me laugh so hard.

@weiurdgurl

8 жыл бұрын

+Sushil Mario You know how in the DNA replication process the double helix has to unzip. Boys would like to do the same thing with a girls jeans. But sorry that I killed the joke.

@weiurdgurl

8 жыл бұрын

+Sushil Mario 👍👍👌😆😆

@isaacmathews4693

8 жыл бұрын

9:22 Lol! :)

When my baby is fussy, putting him in front of your crash course videos calms him.

@catholonelbridget1072

8 жыл бұрын

This is parenting people. Parenting in its finest.

@Awgez24

8 жыл бұрын

Give child minecraft to pacify it. Child pacified for the next two decades.

@coreenthusiast

5 жыл бұрын

Your baby is a nerd

This cleared up the lagging strand confusion I had and I'm so thankful for this video now.

I love the extra effort in tracking the string hank was holding and matching the jiggle animation of the DNA strand with the slight movements of Hanks arm/hand just to create super unnecessary realism. High five animator.

these videos are the best. the editing and detailed number spewing gives us a few specifics we may have missed in individual studies. this "speccy-eyed nerd" has helped a lot of people understand a number of different topics (and has definitely helped me pass a few challenging classes)by showing off his big brains on the internet by describing whatever topic he is needed to, and people like it so they donate and subscribe to his channel at their leisure

Was there an error made at the 5' 3' explanation or am I just having trouble comprehending? Shouldn't the 3' indication circle have been drawn at the third vertice of the pentagonal deoxyribose model?

@toastysplox5338

9 жыл бұрын

I was thinking that same thing. Maybe because the 5 prime and 3 prime bond to one another and so are shown in the same place? There are suppose to be 2 ester bonds...so maybe the ends refer to the phosphodiester bond on either side of the same sugar. That, if still referring to that first sugar, is still the downstream end of the same molecule. I think it is only mean to refer to a direction. I do not know, though. That was just my rationalization.

@oxford_phd

9 жыл бұрын

No you're right, there was an error, it should be from the third vertice of the pentagonal sugar, so on top of the phosphate and not below.

@Procrastinerd

9 жыл бұрын

Hira Javaid Saeed Thanks

@thelurkingpanda3605

9 жыл бұрын

Hira Javaid Saeed Wow I was so confused by that part, can anyone point me to something that can teach it to me correctly?

The 5' to 3' confused me because it circled the wrong thing and pointed the arrows weirdly. So here's what I've understood to help those like me. 1. The deoxyribose, the hexagon with a tail, has 5 Carbon molecules, 1 does not start from the tip, the tip is an Oxygen molecule not a Carbon one, but the next point, right hand side if pentagon is upright, left hand side if it is upside-down, is a Carbon. 2. 2,3,4 follows clockwise for both upright and upside-down deoxyribose, 5 is the tail The circling of both 3s are wrong: 3a) On the left they should have circled the 2nd line connecting the phosphate (orange ball) to the deoxyribose(hexagon) so 5'-->3' makes sense. 3b) The right side should have had 1 more phosphate (orange ball) above the upside-down deoxyribose so that the 3' Carbon could join it, so 3'-->5' would make sense.

@NeoUno866

Жыл бұрын

I’ve been looking for a comment like this, the labels are incorrect for sure.

when watching this do any of you ever think "How the hell does he know this"

HOLD ON A SEC 'WANNA MAKE ONE'?????

@theultimatedoom6896

7 жыл бұрын

Make a DNA model xD

@ARedVelvetBunnie

7 жыл бұрын

lmao I got that in a wrong way

@vanessanelson9330

7 жыл бұрын

lol put on captions/subtitles "( oh dear god)"

@mahdiyadegari8282

7 жыл бұрын

Oh dear

@kingbartholomewthe1above317

7 жыл бұрын

about to type that

This is fabulous, awesome, laudable, appreciable, super-helpful, fantastic stuff. Hats-off to the Crash Course™ team! and....... the way Hank introduces or sticks in humor in between is just too funny! Thanks a ton, Ramana

Got an 83 on my Biology exam :D goodluck to ya!!

@TheHappyHummy

4 жыл бұрын

You suck I got a 100

@aimee-hyj

4 жыл бұрын

@@TheHappyHummy higher marks doesn't equal a better person, clearly

@nathanhe4214

4 жыл бұрын

@@aimee-hyj lmaooo preech

@emmasabat5926

4 жыл бұрын

@@TheHappyHummy Two can play this game. I got a 112 on my last bio exam.

Watching in 2019, I LOVE CRASH COURSE

i have never understood the 5 prime 3 prime thing...,and probably never will.

@Androctonus84

7 жыл бұрын

This video won't help with that, since they circled only the 5' carbon on each sugar, but labelled half of them 3'.

@conceptswithkat3045

7 жыл бұрын

Well if it helps, nucleotides are added to the 3' end because it has a free OH group which reacts to form the bond, so they're being added from the 5' to the 3' direction

@georgiamitchell3692

7 жыл бұрын

No one understands, not really.

@dhruboriley2931

7 жыл бұрын

Its chemistry :'3

@abigailh7223

7 жыл бұрын

Look "5 prime and 3 prime DNA diagram" up on google images. Look at a diagram of a single piece of DNA (as in, not the chain, but one rung of the ladder, made of three parts). It should show that the "top" of each DNA rung (at top of phosphate) as "5 prime", and the "bottom" of each rung (at bottom of sugar) as "3 prime". Therefore, as they chain together, you'll have one side of the DNA helix ladder with all the 5 primes facing up, and the other side of the DNA ladder helix with all the 5 primes pointing down. (and yes, he mislabeled the 3 prime and 5 prime in the video). (Why are these parts of the DNA called 5 prime vs. 3 prime? It has to do with the naming of the Carbons in the carbon rings involved. See W douglas Driver's comment somewhere else under all these replies to NOBEL ADHIKARI for a good explanation...)

Thank goodness for Crash Course. Biology final, anyone?

Thank you for this video so much! I was having so much trouble understanding replication of the lagging strand, but now that I watched this video I understand everything. Out of every video I watched on replication, this video explains it the best.

I'm currently studying Biosciences at uni, and I it made me so extremely happy to see that my lecturer had linked this video on our website, for us to watch!!

I have a Bio test tomorrow and I'm so confused but this video helped so much!

@killyourbunny

8 жыл бұрын

+Veronica Bursek-Krekling wow you must be so smart

@veronicabursek-krekling6349

8 жыл бұрын

+MeepMeepTheMemeCreepBeepBeep I'm sorry, what is that supposed to mean?

@killyourbunny

8 жыл бұрын

Veronica Bursek-Krekling you dont know what smart means?

@veronicabursek-krekling6349

8 жыл бұрын

I can promise you that's not it, bye

@killyourbunny

8 жыл бұрын

+Veronica Bursek-Krekling what?

im not human I look like one but I have 2 hearts and when I die I regenerate can u do that?

@sarasawchuk229

9 жыл бұрын

OMG riversong .........."Spoilers"

@hannahcify

9 жыл бұрын

DOCTOR?? IS THAT YOU?

@forestriver3282

9 жыл бұрын

no its River ;) SPOILERS!

@hannahcify

9 жыл бұрын

no!! DOnt spoil it i started the show last week and I'm only on season 3!!

@JrIcify

9 жыл бұрын

I feel sorry for you people so blinded to the uncommunicatable beauty and wonder of the natural world we live in that you need to go into this fantasy bullshit to release dopamine and/or serotonin in your brains. This reality is so... I don't even know what word to use. It's more fantastical than any MLP or Doctor Who episode you've ever watched. If you could see life as it was, you wouldn't give a shit about those things. I hope one day you awaken to it because I care about you and your happiness. Yes you, the one reading this. I care and wish for you to one day feel the true wonder at life that fantasy and fiction can never give.

*Thank you so much for this video!* I have a mini test tomorrow to do with *Structure and Replication of DNA* and this is as close to what my teacher has been teaching in class, than any other resource I could find! I have watched this video a couple of times now and it's not boring at all, in fact *i'm picking up a lot more each time I watch it!* Now, i'm off to find out more about "semi-conservative" as I still have no clue about it, but I think this video has helped me to understand it a little even though it wasnt mentioned haha once again *thank you*

I love your lectures. It's not boring. Thank you for sharing your knowledge.

Everyone always complains about him talking too fast... It's not that fast at all, you should hear me talk when I'm interested in something.

@beckylieb2637

6 жыл бұрын

he has a lot of information to cram into a certain space of time, and if your brain has to work harder to keep up... it works harder at everything else... very clever Hank, very clever! make is slower if you need to.

ap exam on monday, anyone?

@DangerouslyFast

9 жыл бұрын

Same

@anastasiadancer1

9 жыл бұрын

Yup

@ailidavid7599

9 жыл бұрын

Hyerin sameeee

@hydrogeddonn

9 жыл бұрын

Hyerin Yup and the book is basically a waste of time for studying......

@daaaniphantom

9 жыл бұрын

Hyerin *crying

Thank you so very much for the sacrifice of time and effort to make something so succint. I have an engineering background, but love learning, and this was just superb.

luv this dude. couldnt pass my tests without him. he has the only non-boring vids