0:00: 🔬 Dr. B explains the antibiotic clindamycin and its potential impact on the gut microbiome. 6:02: 💊 Clindamycin is a broad-spectrum antibiotic that can treat a range of bacteria, including anaerobes, but it also destroys the beneficial bacteria in our gut. 16:34: 🦠 The speaker recommends taking a specific probiotic, saccharomyces boulardii, at a specific dose to protect against developing diarrhea and C diff infection while on antibiotics. 17:59: 🔬 Probiotics may negatively affect gut recovery after antibiotics, based on a study with mouse models and limited human data. 23:55: 😮 The speaker took antibiotics and tested their gut health before and after, finding that the antibiotics had a significant negative impact on their gut microbiome. 29:58: 🦠 The speaker discusses the importance of live fermented foods in improving gut health. 34:41: 😔 Taking antibiotics can cause a shift towards an unbalanced microbiome, allowing bad bacteria to flourish. 40:20: 🔑 Recovery time from antibiotic use varies among individuals, and personalized advice based on microbiome data could be beneficial in the future. 45:42: 🔑 The use of antibiotics in healthcare is widespread and often unnecessary, leading to negative effects on the gut microbiome. 50:48: ✅ Taking care of your gut health in the long term involves consuming lots of fiber, practicing time-restricted eating, getting enough sleep and exercise, and being mindful of the impact of antibiotics. Recap by Tammy AI

@susanneblakowski4060

9 ай бұрын

Thank you very much!

@Lomogrammaton

9 ай бұрын

Thanks mate 👍

@atmanand5802

9 ай бұрын

💖💖💖

@constancegreiner906

9 ай бұрын

Nice! ThAnk you!

@Lomogrammaton

9 ай бұрын

@user-me2zc2pe7x Ode Oshi!! oh brother another Nigerian scammer 🤦🏻‍♂️

My mother almost died from C-diff. After a course of vancomycin, I fed her kefir and Saccharomyces boulardii (antagonist and the kefir seems to give it a foothold) Any time she has even the vaguest symptoms I give it again - she’s 102 now. Go mom.

@panamericaco

Ай бұрын

We make our own kefir but didn't help with chronic diahrrea. I just ordered the boulardii, maybe that will help!

@mysticm1543

Ай бұрын

Your mom is lucky to have you

@lisathomas5719

11 күн бұрын

I admire your devotion to your mother.

My mother died from a C-Diff infection that she contracted after a couple of courses of broad-spectrum antibiotics used to treat a respiratory infection. Since then, I've refused several antibiotics in favor of ones that had less of a C-Diff risk. I also had a suspected allergy to penicillin after I got a rash when taking it as a child. My doctor recommended I be tested to see if I truly was allergic. I went to an allergist who determined that I wasn't allergic to penicillin after all. Thanks for discussing this very important topic. Great podcast.

@marynoonan6111

9 ай бұрын

Sorry to hear that about your poor mum ❤

@niamhbyrne4036

9 ай бұрын

Does movicol damage the gut microbiome? Please answer 🙏

@filo2517

9 ай бұрын

Penicillin allergy is an odd one, I used to get a rash a few days after starting a course, and assumed I had an allergy. From what I have read since then though it probably wasn't an allergy at all, as it was just a flat red rash rather than a raised rash. I should get tested properly as the "mycins" really aren't that pleasant for me to take

@vivienstratton4280

9 ай бұрын

In 2007, my Mum died after a year of antibiotics finally culminating in C-diff. She must have been very strong! When I asked about probiotics for her the doctors had no idea what I was talking about!

@basketballfan5763

9 ай бұрын

U SOUND IRISH....ME TOO....I HAVE BEEN PUMPED WITH MOVICOL WITH CONSTIPATION FOR YEARS AND SUPPOSED IBS....I AM ON KETO 6MONTHS OFF ALL SUGAR AND MOST CARBS AND MY CONSTIPATION IS MOSTLY GONE....some plants were the worst culprits for causing it....lentils chicpeas and beans were the worst....I still adore these but sadly they are the very rare treat now in a miniscule portion size....coffee is great instead of movicol. @@niamhbyrne4036

2 months ago I had 4 courses of antibiotics due to a severe tooth infection and feared the worst for my gut microbiome as I felt I'd been poisoned. I'd not had antibiotics for more years than I can remember. I'm over 80 and never take ultra processed foods and have been on an organic diet for 40 years to avoid taking antibiotics in meat. Very useful information in this podcast about what to do next. I will increase time restricted eating and take more fibre, kimchi, kefir, kambucha etc and hope my good bugs win the battle! All Zoe podcasts are SO useful. Thank you.

@oscarlovesmochi3356

9 ай бұрын

Miso paste is also a good option and it tastes great. But I found supplementing with butyrate to be the most healing.

@silviofontana3666

9 ай бұрын

at 70 yo, I was nuked twice with abx both orally and up the bum via colonoscopy to wipe out Basto and Defrag, then got pneumonia 3 times in two years and my microbiome testing, twice, which cost about $1000 told me that I hav NO measurables levels of bifio and Lacto bugs, and I am now, not able to re introduce these by probiotics or pre biotics or fermented foods, my gut is destroyed, and I ate the same as you all my life. ABX are a curse.

@yuppers1

9 ай бұрын

You might want to get an ultrasonic toothbrush like the Emmi dent (it's German). It kills bacteria in places like under the gum where you have dental work. My dad is over 70 and has always had big issues in this area and is now finally ok. He was spending a lot on endodontists and periodontists and ruined his gut with antibiotics

@janglestick

9 ай бұрын

ive been replacing not only all processed foods but almost all carbs with longer chain multiple stage 'ancient' storage foods. The best result has come from replacing noodles, breads and even rice with mostly soaked or sprouted whole grains ... Organic Wheat Berries have been the best, the energy is so much more stable and it does satisfy my remaining carb addictions. Soaking really helps, (like with almonds) and then you can cook them a couple more ways on top to go with whatever food. Or fully cook them through or blend them to use them as a great thickener. But mostly it's nutrient dense meat and rotating different fresh green (sometimes "spicy", cruciferous or sulphurous) sprouts in the morning. There's a lot to indicate that the best time to eat a little fully raw greens that might give your body a tiny bit of a hormetic challenge is by "browsing greens" the way you would when you woke up in the wild, force your body to make do for a little while. But the rest of the day it's cooked meat and cooked rotating veg, obviously it brings out much more of the nutrients. OK take care, hopefully I'm still taking in and adapting as well as you are in a few years.

@carolmiller9066

8 ай бұрын

I am of a similar age and position although I’ve not been organic for so many years I have stopped eating beef and chicken except on rare occasions. Because of a bout with Anemia I try to ear some meat in the form of grass fed bison also grass fed butter. I lost interest in fast food and on the rare occasion it tasted awful to me. I recently finished a 10 day course of an antibiotic for dental reasons and wiped out my gut. It caused the most massive diarrhea of my life even though I took probiotics and kefir, kombucha etc. Until now I’ve managed to avoid getting any colds or flu or even Covid-19, even when my son who I live with had these infections. Having this video helps me to see what I need to do and to avoid any circumstances that would entail antibiotics at least until I feel my gut is working properly.

I suffered food poisoning and ended up with bad bacteria in my small intestine. Broccoli sprouts saved me from possibly a lifetime of ibs. I am amazed at the effectiveness of these sprouts to heal my gut.

@brendabrown166

13 күн бұрын

What brand of broccoli sprouts did you use did you eat

A suggested beginner instruction to making sauerkraut at home: - get a cabbage (or grow one) - slice it finely or coarsly or however you would like to eat it - weigh it and measure out 2% salt (my preferred ratio but do your own research, they say to use salt without iodine) - mix the salt into your chopped cabbage and give it a nice massage - this is a little workout. -let the cabbage-salt mix sit for a couple hours and come back and massage it a little more. It should be releasing some water by now. - sterilize some jars (boil them for some minutes) - the jars/containers should let gas out but not air in, so maybe you need some fermenting lids or other fermenting systems. Or make your own invention!! - stuff the cabbage into your jar(s) and press it down properly, preferably the water should cover the cabbage. If you have it, use a fermenting weight or make your own. (Research) - Let it sit in the jars at room temp for at least a week. Some leave it veeeeeery long (months) some shorter. - When you think it is good you can store it in the fridge, it’s still alive just fermenting slower so the jar can rupture if the lid situation is absolutely sealed. - Enjoy P.S . The internet is filled with great tips on how to do this besides my suggestion. Have fun!!

@t2hbunny

3 ай бұрын

Also, dont heat the saurkraut. Eat it raw or even jst enjoy the juices

@cathycoryell2351

Ай бұрын

Good explanation. I was told use pink Himalayan salt, or celtic grey salt. Also, allow mixture to sit on counter (room temperature) for at least 7-10 days, before you start consuming it.

As some one who suffers from anxiety and gut problems I recognise that Jonathan may be in the same boat. His body language kinda screamed that. We live in very stressfull world so no judgment and probably just talking about what happened could also be really anxiety inducing. Anyway working on stress reduction is super important for our gut health. For me walks in nature listening to music help. Saying no to people is also really good. I cant exactly preach too much because Im watching this video for a reason haha.

@oscarlovesmochi3356

9 ай бұрын

Well said, Ross.

@backyardpc1656

8 ай бұрын

@@user-me2zc2pe7x Is Johnathan, Doctor Obalar or are you just pushing people to go to that Doctor's website?

@Mimiismimi100

4 ай бұрын

I agree 💯! I have same symptoms as you. Best to try to relax, as much as possible 🙏🕊️🌿✨

@fifinoir

Ай бұрын

Inversely, working on our gut health improves our issues with anxiety. Isn’t the stomach our second brain?

With the injury Jonathan had the main reason to give broad spectrum antibiotics [not mentioned in the podcast] is to prevent osteomyelitis [bone infection]. Broken skin + broken bone = high risk of bone infection. If they put a wire into the bone to fix it, the risk is even higher. Once bone infection takes hold, it can require long-term [even 6 months or longer], and often a combination of antibiotics to get rid of. So the surgeon was quite right to prescribe antibiotics to prevent this.

@adabadada

9 ай бұрын

Totally agree. The description of the injury sounds like an open fracture. Definitely warrants strong antibiotics or risk a bone infection, which would be incredibly difficult to treat. If it were me, I would definitely sacrifice the gut microbes. Risk vs benefit.

@makeadifference4all

9 ай бұрын

Plus Jonathan told his doctor that he probably was allergic to penicillin.

@00Tenrai00

4 ай бұрын

@@adabadadanot quite cylindamycin was prescribed for the fear of MRSA. Unless there were cases previously identified at the said hospital there was no need for this. Cyclosporines would’ve worked just as well. Along with topical antibiotics such as powdered vancomycin. Doctors don’t have the time or the patients to curate individualised treatment. It is a cookie cutter one size fits all approach here. Therefore learn a little medicine. And remember, sickness is GOOD for business!

@00Tenrai00

4 ай бұрын

⁠not quite cylindamycin was prescribed for the fear of MRSA. Unless there were cases previously identified at the said hospital there was no need for this. Cyclosporines would’ve worked just as well. Along with topical antibiotics such as powdered vancomycin. Doctors don’t have the time or the patients to curate individualised treatment. It is a cookie cutter one size fits all approach here. Therefore learn a little medicine. And remember, sickness is GOOD for business!

@lindawee5187

4 ай бұрын

My daughter had osteomyelitis & antibiotics made her extremely worse, caused the osteomyelitis in her foot to worsen. We found out she has crohns since it was weird antibiotics made her worse. Took her off all medication & started feeding her anti-inflammatory diet. She’s still recovering now

A very good podcast. Back in the 60s I was given large doses of Tetracycline for acute acne. Neither I nor my doctors made the connection between this treatment and the years of subsequent suffering I had from what was thought to be IBS. The impact was both physically and mentally tough.

@samkampschmidt5463

9 ай бұрын

Greetings. I resonated with your reply on this Zoe broadcast and I was compelled to respond because I too as a teenager with some acne was prescribed tetracycline, which I took for a few years daily without knowing how detrimental this has ultimately would be and the doctor just kept prescribing it like it was candy. Clinical doctors back then and for many years since were clueless as to the negative ramifications from taking antibiotics and I like you have have suffered tremendously ever since😢 I could talk endlessly as to how this iatrogenic medical maleficence significantly destroyed my microbiome and my overall heath. More recently I have discovered that my chronic health issues were especially compounded by the fact that one of the normal digestive bacteria (Oxalobacter formigenes) that reside in the colon is principally responsible for metabolizing oxalate in the intestinal tract, which tetracycline will destroy. I had been consuming large amounts of food that were high in oxalates, which were building up in my body as of a result of no longer having any Oxalobacter formigenes in my gut. This can predispose someone like us in having chronic health conditions for example kidney stones and in my case severe myofascial pain syndrome as well as IBD. If you have had issues in this regard I would first encourage you to check out the work of Sally K. Norton who is all over the internet and KZread. She also has a new book out entitled “Toxic Superfoods: How Oxalate Overload Is Making You Sick--and How to Get Better” It would be so good to follow up with you to compare notes and achieve more clarity about our common ground. Blessings!

@basketballfan5763

9 ай бұрын

been there Ireland in 1995......been ill EVER SINCE.....SEVERE ACNE....1000MG A DAY OXYTETRACYCLINE FOR 6 MONTHS...CURED ACNE....F'ED UP MY STOMACH FOREVER MORE.....

@theancientsancients1769

9 ай бұрын

Same here I was given that too!

@lauraw.7008

6 ай бұрын

43:30 I thought recent studies indicate 3 days; max 4 days of antibiotics for a generally healthy person. Ten days is twice what most people need.

@theancientsancients1769

6 ай бұрын

@@lauraw.7008 Antibiotics more than 5 to 7 days is outrageous. Some give 2 weeks these days to many

The reason for clindamycin is that no other general antibiotic has better bone concentration. Reaching the toes with a systemic antibiotic carries far more challenge than reaching the gut. Let's talk about why there is a risk of infection and what can result from it. The injury was a crush injury, so bone was broken, exposing it to greater risk of infection from any old bacterium that might be floating around in the blood and stopping in the fracture hematoma, whether it came from skin or gut or anywhere else. Blood flow in this case is further impeded by the fact that this is a crushing injury to soft tissues, including blood vessels, around, to and from the bone. And no bones except toe bones are further from the heart, with more delicate blood supply -- nor closer to the ground's supply of germs, nor farther from our eyes, which direct conscious attention. If even one toe became infected, that might have resulted in amputation. Toes are not ornaments. They function in balance, stability, strength for walking and running, and that applies more than double to the big toes. Lose them, and you will be shocked by how much you miss them. Now, add that history of difficulty with blood sugar control -- prediabetes, if you will. When a diabetic gets a foot infection, it tends to be a mixture of multiple bacteria, hence the prophylactic use of a general antibiotic. When a diabetic undergoes ampution, even of part of a single toe on only one foot, the risk of further infection and amputation up that lower extremity grows. This leads to what is known as serial amputations. Even if only one lower extremity is initially affected, protecting it so it might heal means putting extra stress on the other lower extremity, and when that starts to undergo serial amputions, it is a steady creep toward an early death. As a residency trained surgical podiatrist who then became a residency trained orthopaedic surgeon, this is why I would have put consideration of the gut microbiome below the risk of foot infection. Sure, I would have kept a keen eye out for C.diff colitis, but in a patient with PCN history, I would have been afraid to risk anaphylaxis, because even if it is so rare for cases in which the history is that old, it is deadly enough that it would kill far faster than C.diff.

@samatoid

9 ай бұрын

I had a foot infection that would not clear up with multiple types of powerful IV antibiotics that two different hospitals administered. I then had an infectious disease specialist from that last hospital who insisted I had a fungal infection. The antifungals did no good. When I finally got out of the system (not cured) I went to a podiatrist who gave me a prescription for topical erythromycin which immediately cleared up the problem.

@pegacorn13

9 ай бұрын

I'm not a medical provider but as you said, this sounded like a super intense injury and it seems like taking the clindamycin would be worth the risk. I'm certainly not a fan of taking antibiotics all the time when they're not needed and I eat Kimchi everyday but when something as serious as your bones being crushed occurs, I believe antibiotics have their place. I was recently in a bike accident and within a few hours, the wound on my hand sprouted that scary red line and started traveling up my arm. I was given doxycycline orally right away and took it for seven days. The line disappeared within a day. And yes, it was summer and super sunny but staying out of the sun and risking a yeast infection was worth killing that infection. I didn't wind up with a yeast infection (something that I've encountered before with antibiotics) and I'd like to believe it was all the Kimchi I'd been eating that prevented it. So what I'm gathering from this conversation is eat your fermented foods because chances are you're going to need to take possibly life saving antibiotics more than once in your life.

@renarich4942

9 ай бұрын

But this is a commercial channel. Anyways I have no degree which you may realise from my question but Couldn’t they inject the antibiotics into the foot

@tanyakilbane7636

8 ай бұрын

Thank you for this explanation! Where is your channel?!?!? :)

@christopherchander2754

7 ай бұрын

Excellent. Thank you for sharing your perspective and possibly the perspective of the attending physician. Look, I'm no fan of the medical/pharmaceutical industry, but this reminds me, as it should everyone, there are still doctors who save lives everyday, and while we may question their methods, often out of ignorance, we cannot argue with their results. Personally, despite our differences, and while I may never fully trust them, I respect and appreciate all the good doctors out there.

I required surgery for two dental absences back in 2021 and was also prescribed Clindamycin. This led to dysbiosis, and two lengthy terms in hospital, having developed Clostridium Difficile. After leaving the hospital, I found I couldn't digest certain types of food, and importantly had to significantly reduce portion size for a year or so due to irritability. If anyone is reading this and has similar problems with a sensitive colon and a compromised gut, supplementing with butyrate capsules proved extremely useful for me. I still supplement to keep my good bacteria fed. My quality of life has improved substantially, largely because of changes in diet and supplementation.

@thisorthat7626

7 ай бұрын

@oscarlovesmochi3356, thank you for this information. I did a quick search on butyrate and it appears to be very beneficial for gut health. Cheers.

@winniecash1654

4 ай бұрын

Thank you so much for the tip. ❤

@12345621770

4 ай бұрын

I am in the same situation and i use probiotics , l glutamine for leaking gut and betaine hcl

@Jennifer-gr7hn

4 ай бұрын

holistic dentistry only..PERIOD. I had two extractions for obsesses too (criminal dentist years ago drilled a criminal filling on a tooth that didn't have a cavity!!) No antibiotics, only high dose Vit C IV, herbs and ozone. Be careful with mainstream...

52:28 Thanks for a very interesting and valuable discussion. Tim - in a bit of a throwaway line you said something like “ the residual small quantities of good bugs you might still have after a course of broad spectrum antibiotics might be curled up ‘hiding’ eg in the appendix”. This reminded me that some months ago I read a paper about possible impacts of appendix removal, which is a not much studied issue. It occurred to me that given your large database of individuals in Zoe it might be interesting to research whether there were noticeable differences in gut health or recovery post antibiotic treatment in those who still had their appendix and those who had it removed (maybe decades earlier).

@mat1500

7 ай бұрын

Excellent recommendation for a couple of research programs, to see if any significant data might emerge

@clarepollen

7 ай бұрын

I have had gut problems since my 20s didn't look after myself, but also I had my appendix removed. I am also very interested in the removal of my appendix.

This explains my life! I am 29. In my mid teens, I was repeatedly prescribed antibiotics by my (very well meaning) family doctor. Since than, my gut has been destroyed. Despite having a healthier lifestyle than everyone around me, I struggle with general health. I now know a big focus needs to be on restoring my gut. Engaging new age content from the world's leading experts. You all are saviours. 🙏

@lorettamargaret2243

Ай бұрын

Get milk or water kefir grains

The best way to be sure of the efficacy of kefir, kombucha, sauerkraut, yogurt, etc., is to make your own. It isn't difficult and tastes much better than store bought.

@mariakarla90

3 ай бұрын

Thank you for this info,but how do you make them?help please ❤️

@vauxy308

3 ай бұрын

@@mariakarla90 I have been making milk kefir for several years. I actually bought a live colony from Amazon. They Fast ship them with complete insructions. cst me right around $15. but I don't know the price now. I have been using this colony for at least 2 years.

@sarahnovamusicatlanta

2 ай бұрын

Love kefir!

@mohammadhasbibinsuminmoe8214

2 ай бұрын

Take yakult haha

@lorettamargaret2243

Ай бұрын

@@mariakarla90the best dairy ferment you can make is kefir, obtain kefir grains to brew it!! Google milk kefir from grains

Thank you Jonathan, and Dr Will and Prof Tim. I learnt a lot from this podcast.

Haven't watched video throught yet. But when I was 16 i got so fed up with my acne. Was breaking down crying etc. I was wanting to use natural treatments but mother wasn't prepared to spend money at the time. She persuaded me to use antibiotics against my instincts. I used them for 2 years straight! My ance inproved but then came back with a vengance. I remember having diorhoea every day whilst on them. Very much wished I was more stubborn. Or used them for shorter period.

My GP NEVER explained the impact of antibiotics and the microbiome and I didn’t know the questions to ask. It’s only due to watching videos like this and doing my own studying of research that I’m now more aware of the consequences. Still feeling the effects of years of regular antibiotic use.

@northofyou33

4 ай бұрын

I've never had a doctor explain this to me. I found out myself a couple of decades ago, and stopped taking them unless I was very ill. I had to argue with most of the doctors who tried to prescribe them to me. I finally found a doctor who agreed eith me on this, but it was a lot of trial and error first.

@connorobilly

2 ай бұрын

Very strange, eh.

The importance of this is very significant for pregnant women. Passing on gut biome from good diet is so important to get babies off on the right start reducing their risks of so many things...

@ianmcairns

9 ай бұрын

It's now thought that mothers don't donate biome directly to their babies

@lambsquartersfarm

9 ай бұрын

source pls. @@ianmcairns

@Erenm

9 ай бұрын

@@ianmcairnscan you share more about this please? From a pregnant momma

@margaretskinner1416

9 ай бұрын

​@@ianmcairns it may have been a medical professional who was promoting surgical cesarean delivery who made that statement. Every infant when delivered naturally is coated with the mother's bacteria. The mothers vaginal biome is hopefully healthy.

@HelenaBoutel

8 ай бұрын

​@@Erenmthey get their bacterias from their mommy...

This is the best podcast you've done so far! Thank you

What an excellent episode today. Thank you for sharing your personal story Jonathan and good luck in continuing to grow the number of good microbiomes.

Profound and extremely helpful! My primary care doctor is very ignorant about this subject-- I will try to make her to watch this.

Wonderful information …my daughter in law was recently hospitalized and they gave her two rounds in an iv in a weeks time…wish I could remember the diagnosis which was Not discovered initially and just before leaving was actually what she was tested for when she was first hospitalized…a crazy system of cat and mouse where she was …I introduced the fermentation process of sauerkraut as well as the container so she could make her own…luckily I had some going which is a regular in my kitchen..yes it’s late but never TOO LATE to learn more…thank God she loves it and is more than willing coming from a long line of childhood antibiotics with all of their side effects and serious gut problems…thank you for sharing and stay BLESSED!

Thank you. I enjoyed this discussion. Very useful information.

Phenomenal discussion that was presented in a balanced way. Thank you.

Thoroughly enjoyed this episode filled with simple and common sense information to improve one's health. Much gratitude.

@yvonnehadfield1655

9 ай бұрын

So why can the antibiotic not be injected directly into the foot or toe area to be directly as a defence against any infection in that area instead of swallowing and having your good bacteria affected?

p.s. Always impressed by these great Zoe podcasts. Thank you.

fantastic podcast. Thank you for this very valuable information

Amazing information, thank you so much ♥️

A fantastic podcast to watch. As a type 1 diabetic who has just had 3 weeks of broad spectrum antibiotics I listened with great interest to the impact on your gut and the advice from two of the world's foremost experts in the field. I just wish as an insulin dependant diabetic that I could qualify for Zoe but I understand the CGM part of scientific study excludes existing diabetics from taking part. :( I am definitely going to try the chuckling goat kefir and momo kombucha though to reinforce my probably decimated gut biome.

Amazingly useful podcast - thank you. I watched on KZread last week with interest, but have just re-watched it today, having been in A&E yesterday, diagnosed with a nasty eye infection, and prescribed a strong dose of Clarithromycin for 14 days. Thankfully I have some home fermented kombucha and sauerkraut which I will be increasing consumption of, but will also look to buy in some unpasteurised products to increase the diversity, and looking for more recipes so that I can start some more ferments going (I have Will's books, so will start there)! Thank you. The Zoe Podcasts are so useful - do you have a contents page anywhere, so that I know what to look for when I want to go back to re-watch past podcasts?

Very timely, thank you.

Brilliant interview and great summary at the end!

I had a terrible bout of CDIFF immediately after starting Clindomycin in 2010 as a dental prophylactic. It took oral Vancomycin after struggling with it for several weeks to knock it out. Although I eat very healthy including fermented vegetables and probiotics, my digestive system hasn't fully recovered 13 years later.

@12345621770

4 ай бұрын

Me too John!! And we have the same name 😅 i took clindomycin (dalacin c) for my dental implants procedure. And it gaves me finally ulcerative colitis. It sucks.. also after that i took a ton of other antibiotics for other reasons. And now im trying to fix my health and gut.. but its really hard. After so many courses! 😢😢

excellent conversation. thanks!

Thank you for such an educational discussion again.

Brilliant podcast!! Excellent information and advice. Thank you.

Thank you for a very informative video once again. I wish some doctors were more cooperative in hearing the concerns of patients in regards to antibiotics. It is a bit strange that it is up to us, the patients, that we have to educate ourselfs in order to make the right decision whether to take them or not and which types.

@angelahorsburgh9954

9 ай бұрын

Very good point.

@hea7055

9 ай бұрын

I think it's down to them not being trained in nutrition. I wish they were, they'd have so much more to offer us if they were.

I spent years struggling with sinusitis that finally started turning into bronchitis. It was always treated with antibiotics. The time frame was over twelve years. I can’t remember what my resource was but I started taking quercitin faithfully. Twenty years later and I have not had a cold much less a sinus infection…despite continuing to have a post nasal drip either from allergies or gastric reflux. What I wouldn’t give to have one of you as my personal doc. Stomach discomfort and nausea seldom leave. Very exciting work. Thank you:)

@abigail01441

4 ай бұрын

Stomach upset might respond to Digestive Enzymes with your food. NOW® Brand Super Enzymes has proven helpful to me. Vitacost and Vitalife are mail order sources. They are usually available at health food stores.

@madj7152

3 ай бұрын

Do you have constant bad breath? Im suffering from bad breath. 😢

Really exellent and very interesting. Thank you.

Thank you! I’ve picked up lots of new knowledge.

Great timing for me. I'm on my 4th lot of antibiotics in 18 months. Now I know the best way forward.

I feel my gut hasn't repaired from an antibiotic overdose from a couple of years ago. The doctor prescribed incorrectly for an infected sting and accidently prescribed double the dose. I have had bloating, weight gain and IBS. This is really interesting and has given me some ideas of things that might help.

@domi7583

9 ай бұрын

I had the same thing. I was diagnosed with Helicobacter Pylori in my stomach and was first given "ZacPac" to eradicate it and then "Pylera" because it didn't help. But already after "ZacPac", I suddenly had a lot of air in my stomach, along with intestinal noises and constant pressure. Even today, 3 years later, I am still fighting against symptoms that have become weaker. But it is a torture.

@puidemare2337

9 ай бұрын

Have you tried a carnivore way of eating.? Dr Natasha Campbell Mcbride has some very help nutritional information for health@@domi7583

@abigail01441

4 ай бұрын

​@@domi7583 HP in the stomach, might possibly, be toned down with Olive Leaf Extract. I used the Seagate brand. It's a bit pricey, but it worked. I took two capsules, 3 times per day for about 6 weeks. Also, NOW® Brand Super Enzymes with each meal. Expect a lot of belching at first. That was the only side effect. And, do not drink or eat anything cold. The human stomach does not digest anything if the stomach contents are not at the same temperature as core body temperature. Anything cold will shut the stomach off just like flipping a light switch off. During that time, stomach contents will still be either fermenting (plants) or purifying (animal) products. But, normal digestion is not going to occured until the contents of the stomach is warmed up to "core body temperature".

Very informative. I really enjoyed & appreciate this. Thank u guys!

Thank you for sharing your expertise. What a great opportunity to understand a subject matter that is quite complex.

A really excellent episode, thank you! I do hope poor Jonathan's foot is better, sounds awful. It's very comforting to know that if one is forced into a situation where antibiotics are required, it is possible to get the gut and therefore immune system back on track afterwards with good lifestyle habits, whether slowly or more speedily if one is lucky. I feel sometimes there is a bit of scaremongering about, especially from people who market expensive probiotics etc! I have been very fortunate in my 53 years - I think I could count on the fingers of one hand the number of times I've been prescribed them, and certainly not at all within the last twenty, maybe even thirty years. But I have become probably too paranoid about avoiding them at all costs, so this episode was a great source of sensible balanced advice. I have been especially paranoid about my daughter, given the prevalence of their overuse in children. She has only had one course, when she was about 4, and I breastfed her until a couple of weeks short of her 5th birthday, when my milk ran out, so I hoped that would help get her gut community back on track. Cross fingers, age 11 she seems in very robust health, but at least now I feel better equipped to have a rational discussion with a doctor about antibiotics should she be advised to take any. Sometimes in this modern world, it seems very hard to do the best thing for your children, in the face of conflicting advice and information....

@carolinelaronda4523

9 ай бұрын

Don’t vaccinate . She will be fine.

@teressastuckey

5 ай бұрын

​@@carolinelaronda4523there's always an uneducated anti-vaxxer giving bad medical advice.

Very interesting conversation, I would be interested to see if Zoe can get to the point where they measure the amount of Antibiotic resistant bacteria in the gut as well, or is that already happening? Then determine a course of action to reduce this resistance.

Excellent podcast, absolutely riveting

After years of fighting to get my gut health something close to "normal" I then had terrible food poisoning in 2021. Have not been the same since. Will try to incorporate some of these strategies.

Here in France, untill about 10 years ago, doctors prescribed « ultra levure » or a yeast pill, with anti biotics. They stopped prescribing it as it wasn’t reimbused by the health service. I’ve taken dozens of antibiotics over the years, as my COPD led to frequent infections. Since I’ve been into fermented foods and time restricted eating, I feel much better. The last soar throat I had cleared up in a day or two. Before, it would have turned into bronchitis then needing antibiotics.

@masterprattu

9 ай бұрын

what fermented foods do you have ?

@theancientsancients1769

9 ай бұрын

Have you looked into Lung Support by Xtend-life? And GLYNAC too for the lungs ?

@WalkingDday

9 ай бұрын

@@masterprattu Saurkraut, kefir, raw milk cheeses, cider vinegar.

@WalkingDday

9 ай бұрын

Are you suggesting this because you've used it or is this just a spam promotion? @@theancientsancients1769

@lpatrick357

9 ай бұрын

Smoking mullein is great.

Really interesting and informative podcast. Thank you. As someone who takes antibiotics daily (doxycycline), and has for several years now, I would be interested to know whether there is anything I should be taking or doing to protect/improve my gut biome given my long term usage. I generally eat a wide range of veg, fruit, legumes, nuts etc and have been following an IF diet since starting the Zoe IF study in December. I note the importance of increasing fermented foods but would welcome any further advice on this. Thanks.

@GeoRockNerd

9 ай бұрын

Resistant starch is a great food for the bugs in the microbiome, you could try eating more of those foods along with the fermented foods.

@lpatrick357

9 ай бұрын

Fermented cabbage. Cheap and wonderful for the gut.

Thankyou great podcast.very well explained by the best specialists. Intelligent questions, very informative..I have diverticulitis (hospital) & IBS ..will try fermented foods ..

Thanks for all the info, helps a lot.

I ended up getting a c diff infection that lasted nearly a year. The irony is the course of antibiotics wiped out my microbiome but helped to rewire it to a healthier microbiome after it with wfpb and pro and pre biotics. I was able to go into remission from an autoimmune disease.

@vigour09

4 ай бұрын

Hi, do you mind sharing what wfnb pre and probiotics you have used? My husband got very sick and was in antibiotics. Would be very helpful as he has autoimmune too. Thanks

Will you do a 6 month and year update as we are invested in knowing if your gut recovers thanks and take care xx

This video is so helpful. Thank you

wow this is excellent podcast, really enjoy it! Thanks so much for raising awareness in this topic.

My son was put on a long term dose of Antibiotics on 2 different occasions for chronic ear infections. After the second round his personality changed. He went from a kid that ran everywhere and was very happy to a child that did everything slowly, began gaining weight and became depressed. He now has MS after having Covid. He still struggles with weight.

@user-bm125

5 ай бұрын

Did your son get the Covid Jab? Did MS come after son had the Covid-infection or the Covid-Jab?

@demetriafravel6556

5 ай бұрын

@@user-bm125 The symptoms started after we all got Covid

@teressastuckey

5 ай бұрын

​​@@user-bm125always leave it to an antivaxxer know it all to blame everything on the vaccine. Stop harassing people because you're uneducated and paranoid.

@lisalynch629

4 ай бұрын

Happened to my child as well

@csb1143

4 ай бұрын

Look into methylene blue… heard it may help with gut issues. May help with brain issues as well… lots of Drs videos to watch on KZread talk about it

Love your videos they have taught me so much. Curious how does Chemo Therapy effect the gut microbiome? I was diagnosis with breast cancer in June of 2022 and my gut has never been the same. I am working on getting it back to normal and finding it difficult. Not sure if it's because I have still not gotten my appetite back or because the Chemo killed more then just my cancer? Love to hear your thoughts.

Thank you for posting these good suggestions. Best Wishes.

Thanks again for an evidence-based discussion about fermented foods and more

After taking antibiotics for a viral infection I developed dysbiosis and became suicidal. Thankfully I fixed things with a good probiotic supplement but it's crazy how easy antibiotics are dished out and how ignorant some doctors are.

Had a mitral valve operation about 9 yrs ago. Went to a urologist recently who gave me Cipro after having me sign a release, like I know the repercussions of taking such a drug. I wonder now if the doctor even read my history. I’m getting more and more hesitant to trust today’s medical system.

@janco333

9 ай бұрын

Cipro is one hell of a nasty antibiotic

@someoneoutthere4061

9 ай бұрын

If a mitral valve gets infected with bacteria, you're looking at another operation and/or long-term antibiotics. So I'm not surprised uro prescribed cipro. Antibiotics save lives, after all.

@rowdyposs

9 ай бұрын

Was it prophylactic before a urology procedure like a prostate biopsy? To protect you from a heart infection?

@makeadifference4all

9 ай бұрын

I have a heart murmur, so a doctor told me to notify dentists before dental surgery because they might want to give me Cipro prophylactically. Fortunately, dentists have declined to do that.

@lyndathorpe280

9 ай бұрын

I had hole in the heart surgery 41 yrs ago and it was at least 10 years ago when the evidence base changed for no longer needing anti biotic cover for dental procedures. I’ve had other minor procedures as an inpatient and no antibiotics given and no infection followed. This podcast is basically a sell for the Zoe test kits and I’m more sceptical of that rather than other medical professionals.

spectacular channel about nutrition and the method developed by ZOE to customize diets, based on genetic individualities is phenomenal. Looking forward to arriving in Brazil. Hello Jonhatan and ZOE, come soon I need your help.

I really enjoyed this in-person discussion and very interesting subject.

One of your Drs suffered sinus for years. I to had antibiotics for sinus gor 20 years. A South Aftican Dr sent a blood test which showed I had low Alpha one antitriypsin. Russian Chemist put me on an enzyme from cattle bile. After yhis I didn't suffer from sinus infections.

Very interesting topic, I even ferment myself😀. As a Kidney Stone Treatment Complication I had high fever for several days and bloody urin. So when I went to the hospital the Specialist Doctor recommended Antibiotics Treatment against the suspected local bacterial infection. I told him that I was worried about damaging my gut bacteria and story short I was treated with *a less strong antibiotic*. Maybe I suffered the fever a day longer but in the long run, after over a week at home now the diarrhea gets really better. TALK TO THE DOCTOR! Some *do* have understanding of how I M P O R T A N T your gut world is. At least they learn that antibiotics can harm your digestion. I was really thinking about declining the antibiotics. But since I already were in the Process of the Kidney Stone Extraction Procedure I already had a ‘bridge’ to the affected Kidney inserted. So the Specialist suspected a local infection. Strangely Urin Analysis was negative 🤔. Generally my recent diet is low-lectin, low-oxalate! and now with real ferments and fiber 💪.

Excellent info

when the video opened with NO ADS I hit subscribe and the notify bell straight away!!

@TaijaSkyDragon

4 ай бұрын

Their broadcast is a commercial for their company ZOE

In 2019, I had antibiotics to treat for a cat bite... Ever since then I had awful GI symptoms, and after nearly a year found I could not tolerate many gluten containing food (wheat, oats, rye). I now experience a lot of IBS symptoms and although I am fairly good at managing and mitigating my symptoms - it really has affected my daily life, food choices and confidence - all from a simple course of antibiotics.

@seeingyouontube

9 ай бұрын

Or maybe not? Maybe it’s the gluten or glyphosate inoculated grains.

@andrewroberts8959

9 ай бұрын

If you are not already, do everything they suggested. I had antibiotics after a human bite - 14 days of something very strong. Had GI symptoms/a weak gut for years afterwards. Over time I ended up doing everything they have suggested here and it really does work.

@drderrickchua

9 ай бұрын

Bartonella infections from cats can cause Ulcerative Colitis. Don't be too quick to blame too much treatment as the cause of your problems. It could have been too little treatment.

@ZsuzsaKarolySmith

9 ай бұрын

Oats are actually gluten free - it’s just that during manufacturing, they might get contaminated with gluten from other grains, but unless you have Cealiac disease, you wouldn’t notice.

@dawnelder9046

9 ай бұрын

​@@ZsuzsaKarolySmithActually all grains have their own version of gluten. Oats, like rice contain gluten that most people do not have problems with. However a celiac friend has the worse problems from rice gluten. Quite a few celiac find they half to go grain free to remain symptom free.

This is really interest. One of my friends who never takes antibiotics if she can help it was recently on a course of them..She has had anxiety ever since. I wonder how much mood is affected too by the microbiome. Thank you.

@janco333

9 ай бұрын

The macrolide family of antibiotics can give severe anxiety lasting several months. Been there, got the t-shirt.

Amazing podcast and thank you so much Jonathan for being open. Great dialogue and insight

👍🏼 thank you for the valuable information!

My husband got C-diff from clindamycin and had to have a fecal transplant after getting very, very ill.

I found that fermented foods and a high fibre diet were the worst things to have after antibiotics, and led to long term gut dysbiosis. Probiotics and fermented foods and fibre and plant foods are good if you already have a healthy gut.

@OZMAZZ12

3 ай бұрын

Absolutely 👍

@lucakat9262

2 ай бұрын

What do you suggest then?

@Sagrad0Corazon

Ай бұрын

@@lucakat9262Potato variety or brown rice diet to recover

@princessrejoicing

Ай бұрын

i agree 100%!!!! those with a compromised gut cannot digest those very very complex carbohydrates!

I took clindymcin and my body has been out of whack for 7 months. My NHS eczema nurse recommended the Mediterranean diet and mentioned that I should look into Tim Spector. I've had a tests done to see if there's any really bad gut bacteria in there which was negative. I'm still going to focus on restoring the balance and optimization.

Amazing. I guessed it before it was mentioned and I'm not a doctor. Having a hard time with antibiotics myself, I have in fact used Saccharomyces boulardii - it even helped ease stomach pain from the antibiotic.

My wife had really bad diverticulitis to the point of infections and bleeding. Started a daily probiotic taken with 8 gms of psyllium fibre after the antibiotics, stayed with it, a year later no recurrences.

Sure wish you had addressed elective surgeries that are done everyday for people over 40. No doubt that i destroyed my gut after two surgeries back to back. I developed sore spots in my stomach and kept on with my omnivore diet. I was obviously exposed to some very bad gut microbes that created the sore spots. I recently went to Peru where, with my torn up stomach and low immune response due to 6 rounds of chemo after fighting cancer, I contracted giardia. A 7 day round of metronidazole knocked it out. Since recovering, i took Florastor for 5 days while eating loads of kimchi. The belly still had intense pain so I recently started drinking fresh cabbage, celery, green apple, lemon and ginger juice on an empty stomach. I'm at day 3 and can already notice a huge reduction in pain. It's incredible. Please discuss this if possible as this was a multi-faceted situation that i fear many people are silently suffering from

Much, much appreciation, guys!

great discussion

This discussion with Dr. B and Professor Spector makes me appreciate Doctors and medical professionals so much more. I just about lost all trust in Doctors since the covid pandemic came into existence. Thank you all for this discussion! I am not a medical Doctor but I do read a lot and have warned people for many years not to rush to Doctors to get antibiotics. I see it all the time. Acquaintances rush out to a Doctor as soon as they get a sinus infection or a pain somewhere. I know one in particular, who has taken so many antibiotics and who consistently developed diarrhea that this person ended up in the hospital and was seriously ill with C-Diff. Went home and ended up back in the hospital a couple of times. I have no doubt that this person ended up with C-Diff because of the constant prescriptions for antibiotics over the years. Incidentally, my husband and I consume sauerkraut often. I have always loved sauerkraut out of the can but I ended up making it myself a couple of years ago. I will have to revisit fermenting veggies again.

My husband had tooth assistance he allergic penicillin so proscribed strong antibiotic. After reading side affects he refused them and the dentist drained the absis but still advised the antibiotics. My husband never did but constantly rinsed mouth with boiled salty water until healed. Side effects were crohns and If I remember rightly chance of meningitis along with other terrible effects

This was super interesting. Thank you!

I had this gut feeling that I'd like this video ... and I did!

Fascinating. Thank you I have a question In your situation Jonathan you have the luxury of being able to test your Microbiome very frequently which of course Is probably not an option for most people Before you got your test results did you have any symptoms at all that would have given you an idea of the devastating effect of the antibiotics on your Microbiome? Presumably most people wouldn’t know that they had done this amount of damage with the antibiotics Personally I am completely obsessed with my Microbiome having been on the Zoe app for ages and done the personalized nutrition etc. and in fact, Recently, when my GP wanted me to go on antibiotics he said that he was having the opposite argument most people as I was very very very reluctant and everybody else seems to just be demanding them! Thank you very much. Christine

Can you give us the reference for the saccharomyces boulardii paper?

Wow. I learned so much from this video!

I just had a minor surgery to remove a cyst on my foot and apparently they gave me clindamycin in an IV during the surgery. They knew I had issues with my colon because I told them I’d had chronic diverticulitis for years and other digestive issues so I wish they would not have given me clindamycin in the IV. I started having diarrhea about 24 hours after I came home, and now I’m worried about developing gut infections and diverticulitis flare ups and so much more.

My oldest son never had an antibiotic until he was 15 years old. It was difficult to deal with doctors, as they all wanted just to prescribe the antibiotic, just in case it was needed. Over his childhood, I made doctors do strep cultures (3 total), and every one came back negative.

Hi Docs! Thanks for this video. I am 65 years old and have avoided antibiotics for 40 years because I think they cause big problems that don't get solved often. But I've had two surgeries this year and was forced to take antibiotics, especially for one of them because the wound got infected. I took doxycycline, and I don't know how bad that one is. But my gut has not recovered. My problem is that I have severe celiac disease and other food sensitivities and allergies. I react violently to many fermented foods. My reaction to any alcoholic beverage, for example, is every voluntary muscle in my body goes into a painful spasm. It's like a neurotoxin. I can actually get temporarily paralyzed. I can't even have a sip of communion wine without getting some reaction. But I also react poorly to kombucha and other fermented foods and drinks. Kefir isn't an option because I can't have dairy. I'm considering making some cabbage rejuvelac. I've responded well to that in the past. I'm taking a probiotic, but clearly it's not really solving the problem. It's helping I think but not enough. I would be grateful for any suggestions!

@csb1143

4 ай бұрын

Dr Ben Lynch has discussed some of these things in his book ‘Dirty Genes’ it may help you.

Thank you so much for this! I have been fearful of antibiotics and I believe that for that reason, I respond bad to it. My mind is screaming NO when I have it prescribed (last time was for an abscess in my mouth due to a bad rootcanal treatment). The first 6 days of antibiotics I had low bodytemperature (35.6) and was freezing cold. Which was strange because I had, had the same antibiotics 4 years prior and at that time didn't even notice I took it. At that period I wasn't yet aware of the negative side of antibiotics. But this interview has given me a middle ground. Pros and cons plus the knowledge that I can heal myself within, generally, 2 months. Thank you immensely.

I was given an anti biotic when I was in the hospital to re work my "broken" pacemaker. Turns out they made some adjustments, and didn't have to cut. Meantime I had a reaction to the antibiotic ( vancomycin). My face started to turn red, and the person pushing the bed caught it. Sad but true. I was told that it was the speed they were introducing it, and as soon as they lowered the speed, it got better. Still I don't want it again, so it's on my allergy list. I am sensitive to drugs, but I find that doctors/nurses often don't listen. I also have had a lot of sinusitis, bronchitis in my day, which meant lot's of antibiotics. Since being really strict on my wfpb no oil eating plan, I've been better. The few times I've had them, I've depended on the diet to recover. So far, so good.

For fermented foods, I like to make my own sauerkraut and fermented white cabbage. This makes use of the biodiversity that is already present in the cabbage. So you don't get just one species, but maybe even hundreds of different species of bacteria. And likely the more fermented foods [and try eating some raw sourdough] the better - except caution on the ones containing alcohol.

I’ve had C diff twice and it nearly killed me. I have Lyme disease and my liver and kidneys would shut down on the antibiotics to treat it. Vsl #3 probiotics saved me. I had to find out about it from a friend because none of the doctors thought to look for an alternative to me dying from the antibiotics that treat Cdiff. I later saved my grandmother from antibiotic associated diarrhea with this and one of her doctors did ask what I used and wrote it down. (She was in a nursing home). I do use s bulardii to treat candida and bad bacteria from time to time but I’m surprised Vsl#3 wasn’t mentioned. All the suffering I went through as well as my grandmother before finding this. I got my dad on this with diarrhea from abx and irritable bowel and he got the pill form at his pharmacy instead of the stronger packets and I noticed it took longer to work. I just took half a pack a day and was better in 7-10 days and much better after few weeks. This was after months of abx and hospitalization and being told I was probably not going to make it.

@petra5647

4 ай бұрын

Can you explain what vsl#3 probiotics is? Thank you

@nicsxnin6786

4 ай бұрын

@@petra5647 it’s a proprietary strain of probiotics developed to help treat certain medical conditions. It comes in prescription strength and non prescription. You can order it directly or through many pharmacies. It’s very effective for antibiotic associated diarrhea and cdiff as well as several other conditions. I recommend the packets. The capsules don’t seem to be as strong or effective for certain people. You can start with just half a packet and have more control with the dose.

@MrRobkina

3 ай бұрын

Seems to cure lyme also , monolaurin

@nicsxnin6786

2 ай бұрын

@@petra5647 it’s a special probiotic developed for multiple diseases. It doesn’t colonize but it’s a real life saver. If you or a loved one has gut issues please research it.

My daughter was put on antibiotics for cat scratch fever. I didn’t want to do it but it’s life threatening. I immediately got her on pro/prebiotics. Plus kefir. Sometimes you have to choose the hard things. But with God and prayer she wouldn’t be injured by the antibiotics is the way to go.

I almost died from taking clindamycin that was prescribed by a dentist for a root canal. After almost 20 years I am still suffering from gut issues. I now cannot take any antibiotics for more than 3 days without getting very ill! The doctor that diagnosed me said that he wishes they would remove clindamycin from the market because it is the worst to cause c-diff.

I once got staphylococcus. Wounds that grew with 0,5cm every day. The doctor looked very disgusted and wanted to give me antibiotic pills.. I questioned "why giving a pill for the whole body. When it's local wounds". I got a antibiotic cream instead. But I hesitated to use that too.. so I went home and googled what they used in ancient times instead of antibiotics. I came a cross a site that said that the Australians used eucalyptus for staphylococcus. I had an eucalyptus essential oil at home and I did what they say you shouldn't. I took one drop directly at the wound and it dried up and started to heal at once. Now ...one should Never use essential oils if not deluted in other oils. But it for sure helped and was safer than antibiotics. Now once again.. read carefully about essential oils before using them. I would have done it a bit differently today. Staphylococcus love it warm and moist. The essential eucalyptus really dried it up.

This is super interesting. I was one of those kids who took antibiotics every second week growing up (asthma caused by inappropriate immune response to commensal bacteria) and my diet was also pretty poor or, let's say typical, for a 90s kid meaning ultra-processed foods and low fiber. I have had issues with IBS as well as more allergies my whole adult life. While I would love for us to use antibiotics more conservatively I think the balance can swing too far in the other direction with doctors not prescribing antibiotics when the patient would benefit. This is certainly already the case in the UK and the Netherlands (I have experienced both myself). Maybe the focus should be on better infection diagnostics, alternative therapies like phages (which can be incredibly specific and targeted to individual bacterial species) and monitoring. That way, patients would receive the right treatment for specific infections at the right time. We would reduce use of broad-spectrum antibiotics while making sure people don't just have to put up with infections for longer to avoid antibiotic use.

Standout episode from Zoe. Fascinating, thank you. Going to try to track down that 2014 Nature Medicine paper Will mentioned - what a shocker!

Nice discussion, thanks