ACE-I & ARBs | Mechanism of Action, Indications, Adverse Reactions, Contraindications

Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
Join us for our discussion on ACE Inhibitors and ARBs as we continue our lecture series on cardiovascular pharmacology and how to treat Hypertension (HTN). During this lecture Professor Zach Murphy will go into detail on how Angiotensin Converting Enzyme inhibitors (ACE-I) along with Angiotensin II Receptor Blockers (ARBs) are used to lower and control high blood pressure.
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Пікірлер: 330

  • @aserehtavlis2866
    @aserehtavlis28664 жыл бұрын

    I really appreciate your time and effort making all these videos. You're truly amazing and genius. You help me with my exams and really understand how things work. Stay safe and healthy.

  • @deepakkumarsingh4994

    @deepakkumarsingh4994

    Жыл бұрын

    Really good

  • @TheOldMayfieldPlace
    @TheOldMayfieldPlace4 жыл бұрын

    You are so clear in your teaching. I wish you had taught pharmacology when I was in pharmacy school. I am really enjoying your videos. After 30 years I've forgotten some of the specifics of MOAs of the drugs I dispense daily. It doesn't really come up when speaking to my patients, but is the stuff I geek out on.

  • @kimswartz9107
    @kimswartz9107 Жыл бұрын

    You are definitely out here teaching me better than the school I pay tuition to... thank you!!

  • @tuilikaandreas4776
    @tuilikaandreas47763 жыл бұрын

    the sound of your laughter as you repeat the process is so comforting and reassuring :)

  • @hwasunfiower1769
    @hwasunfiower17693 жыл бұрын

    It feel like i experience heaven when i found your channel. This really helps me a lot ❤🔥

  • @apdullahiboss3492
    @apdullahiboss34924 жыл бұрын

    Thank you my second teacher ❤️❤️

  • @Deadlokd

    @Deadlokd

    3 жыл бұрын

    My primary teacher :D

  • @ariespitzfaden6027
    @ariespitzfaden60274 жыл бұрын

    Most thought out and straight forward video on ACE inhibitors and ARBs. Zach, we salute you. I love it when you piece together the mechanisms of these drugs!

  • @debislomp1207
    @debislomp12073 жыл бұрын

    You are an inspiration and have taught me SOOOO much. You make the material interesting and present it in a simple way, making it easier to retain

  • @MrAkooanaih
    @MrAkooanaih Жыл бұрын

    he is a genius in explaining thinig, im supporting your channel and website thnk you

  • @shannonhuntsman7664
    @shannonhuntsman7664 Жыл бұрын

    You’re absolutely fantastic at explaining how it all works! Thank you 😊

  • @mohamedfathi4599
    @mohamedfathi45994 жыл бұрын

    At first, I want to thank you and all of your team for the great work and dedication to make these type of videos that is comprehensive and informative. However, I want to comment on some of the information presented: 1) The Receptor that is responsible for mediating most of the angiotensin II activity is called AT-1 receptor not AT-2 receptor and ARB act by specifically inhibiting AT-1 2) ARB class of drugs ends with the suffix SARTAN like valSARTAN , candeSARTAN etc 3) Continous and chronic elevation of Angiotension has a mitotic activity on vascular SMC and cardiac myocyte and that is why ACEI or ARB are beneficial for cardiac hypertrophy as it lower the progression of this process. 4) Renal effect of these drugs is by mainly antagonize the effect of ANG-II on efferent arteriole which will eventually leads to dilation and decrease intraglomerular pressure. By relieving the stress on glomeruli that is beneficial is case of nephrotic syndrome or kidney disease.Also that is why renal artery stenosis is contraindication as it will cause sever drop in glomerular pressure by decreasing blood flow from afferent arteriole and by vasodilatory effect of ACEI on efferent arteriole. Thank you again for all your efforts. I hope you all the best.

  • @jihaneziati3535

    @jihaneziati3535

    4 жыл бұрын

    You're right

  • @aditiadvilkar2000

    @aditiadvilkar2000

    4 жыл бұрын

    thank you so much sir

  • @arunabhadebnath1894
    @arunabhadebnath18944 жыл бұрын

    The very best of lectures!!

  • @loriakelly7969
    @loriakelly79694 жыл бұрын

    Haven't been to college in 35 years and I can follow you easily. Thank you for sharing your knowledge and style of teaching.

  • @omdah070

    @omdah070

    4 жыл бұрын

    You're welcome

  • @ajithmampitiya7166
    @ajithmampitiya71663 жыл бұрын

    Sir, I have never across this type of teaching experience. Very interesting. Vast knowledge in short period. Highly appreciated. Never forgotten. Thank you very much. Triple gem bless you.

  • @dranthonyasturi9790
    @dranthonyasturi97902 жыл бұрын

    You ALWAYS make sense. Each and every lesson Zach gives is a performance akin to "I SOLISTI VENETI", an Italian chamber orchestra founded in Padua in 1959 by Claudio Scimone. I was at the time at the U. of Padua learning electrophysiology. My congratulations to Zach

  • @filippetrovic9823
    @filippetrovic98233 жыл бұрын

    I am so grateful for this video, thank you truly. It is so disappointing that there channels on youtube that explain things better than professors in universities.

  • @daniellesoileau5234
    @daniellesoileau52342 жыл бұрын

    I swear I don’t even need to go to class because of you!!!! You truly have a gift!!

  • @mesfinabebe9572
    @mesfinabebe95722 жыл бұрын

    This is really an excellent lecture . I am a physician and also hypertensive taking ACE-I inhibitors and helps me for more follow up

  • @annabelle9904
    @annabelle9904 Жыл бұрын

    You're the best teacher ever! Thank you

  • @paulroberts2511
    @paulroberts2511 Жыл бұрын

    Boom! Drop the Mic! Wow, your videos are excellent! I am a DNP and studying for my AANP (FNP) exam. Your content is right on, and your manner of teaching is an extremely effective teaching style for so many types of learners! Thank you, what a great refresher and preparation for my exam!

  • @rosacarneiro6270
    @rosacarneiro62704 жыл бұрын

    Wonderful concise explanation! Love it!

  • @sunshinejoy1391
    @sunshinejoy1391 Жыл бұрын

    Thank u zach for making me understand this so quickly with ur beautiful illustrations and clear explanation...more love to u❤️❤️

  • @robinbentley4982
    @robinbentley49822 жыл бұрын

    Excellent explanation of something that has been so hard for me to wrap my mind around (the RAAS). Thank you for the wonderful videos!

  • @shasha6064
    @shasha60643 жыл бұрын

    I made through first year with your help ..nd u r supporting me in second year tooo 😭❤️ thanks for making pharma easy

  • @architasaha8917
    @architasaha89174 жыл бұрын

    Thank you for your easy way of explaining such a important chapter. Please keep making us rich with your knowledge.

  • @christineb7757
    @christineb7757 Жыл бұрын

    I am so happy I found your channel. I am confident your knowledge and way of explaining the medications along with mechanisms of action, contraindications, etc. will help me greatly in my adv pharm for adv practice nursing. Thank you for your brain.

  • @qazal1116
    @qazal11162 жыл бұрын

    I appreciate your help today and always !

  • @jonathanrogers1346
    @jonathanrogers13464 жыл бұрын

    Just found you a few mins ago off the Neurology | Autonomic Nervous System video. your pretty cool and smart going to start watching your videos bro keep up the good work.

  • @psalmina
    @psalmina3 жыл бұрын

    You are awesome. I didn't find anywhere this more clearly explained.

  • @ohemaadeyemi5233
    @ohemaadeyemi52333 жыл бұрын

    This is the best video honestly. I am dyslexic and the repetition of the RAAS system helps a lot. Thank you! I will be supporting your go fund me, if its still open.

  • @livakuzmane6794
    @livakuzmane67943 жыл бұрын

    I love these videos, they make everything so easy to understand!

  • @akps61
    @akps61 Жыл бұрын

    You are an excellent teacher. I really appreciate your work. Your videos make so much sense. Thanks a million.

  • @dougr2237
    @dougr2237 Жыл бұрын

    Amazing, made everything so clear and one of the only resources to explain bradykinin-ACEI relationship

  • @kasunrodrigo6592
    @kasunrodrigo65922 жыл бұрын

    One of the best lectures about ACE and ARB's Thank you sir....

  • @futurendeavours1596
    @futurendeavours15963 жыл бұрын

    I've never enjoyed a lecture as much as I enjoy this👍

  • @elisa211
    @elisa2112 жыл бұрын

    Love your videos. You break things down so clearly in a way that is easy to understand. The visuals are super helpful for a better understanding as well. Youve made my APN education that much more do-able! Thank you!

  • @NinjaNerdOfficial

    @NinjaNerdOfficial

    2 жыл бұрын

    Glad you like them! - TG

  • @brianedwards5113
    @brianedwards51132 ай бұрын

    I have been following you for years and I almost passed up on this video for a shorter one because it's really late and I have to be up early in the morning but you woke me up with this video. Absolutely crushed it, man! I LOVE the content that you make because you really know how to perfectly scratch the itch of not just wanting to know that " 'x' does 'y' " but HOW it does it. Thank you so much for your content!

  • @user-bz4xp7wy1b
    @user-bz4xp7wy1b7 ай бұрын

    I REALLY LOVE THESE LECTURES...I THANK YOU FROM THE BOTTOM OF MY HEART..

  • @ahmedelhadidy7996
    @ahmedelhadidy79963 жыл бұрын

    I really appreciate the effort you did in simplifying this information thank you , keep going

  • @Di_Moriarti
    @Di_Moriarti4 жыл бұрын

    The great job that makes sense. Thank you!

  • @abeikukimani8565
    @abeikukimani85653 жыл бұрын

    You are a blessing. keep up the good work. You make pharmacology interesting to learn and understand. Thank You.

  • @libertyblueskyes2564
    @libertyblueskyes25642 жыл бұрын

    You have so clearly and specifically answered my questions about the heart failure I experienced and the drugs I am taking. My cardiologists spends about ten minutes with me, not enough time to thoroughly understand. So thank you from the depths of my heart for taking the time and effort to educate all of us.

  • @christineb7757

    @christineb7757

    Жыл бұрын

    You need to be more aggressive with your heart doctor and demand more time and better explanations as it is your life, and you are paying for his time. I'm sure he charges for way more time than he is giving you. Be pro-active. He is employed by you. Ask his office manager if he bills by the hour or the visit. Then explain that if the hour, he owes you money. If it is by the visit, the visit isn't over until you say so or you'll find a physician that will take the time to treat you properly. It's your money and your health. You have a right to get your money's worth.

  • @a30s
    @a30s4 жыл бұрын

    Best explanation of every topics.Thanks alot.

  • @0nevergiveup0
    @0nevergiveup0 Жыл бұрын

    Explained it so well. Love the recapping, i dont think i can forget this now. Thank you for the time, effort and sharing of knowledge.

  • @alinassib6483
    @alinassib64833 жыл бұрын

    I grasped everything...this is really awesome

  • @smileyc2011
    @smileyc20114 жыл бұрын

    I wish I would’ve seen this while in Hygiene school :/ you make it simple to understand! Glad I found it before my board exam though! God bless you!

  • @shun3953
    @shun39533 жыл бұрын

    Awesome way of explanation. I just enjoy your classes.

  • @CiaoColeG
    @CiaoColeG3 жыл бұрын

    About to start clinical for my MSN in a month and I've been so scared because I'm in pediatrics and don't give BP meds and so many others... Your videos are AMAZING!!? I love your teaching style. It's so engaging I missed my turn while listening and driving yesterday 😄

  • @sewndebisdream6953
    @sewndebisdream6953 Жыл бұрын

    Glad to have this info when I go to my doctor.

  • @westfield90
    @westfield90 Жыл бұрын

    So beautifully explained

  • @naelyncarruth6079
    @naelyncarruth60792 жыл бұрын

    Thank you so much for making such clear and concise videos!

  • @cccalifornia7206
    @cccalifornia72063 жыл бұрын

    Excellent teaching.... I learned so much!!! Thank you 😃👍

  • @lilianechick904
    @lilianechick9049 ай бұрын

    Always a very productive class. I appreciate very much your work.

  • @agyekumemmanuel3678
    @agyekumemmanuel36782 жыл бұрын

    I love your teachings. Your PATHOPHYSIOLOGY is always superb ❤😊

  • @suchethagirish8303
    @suchethagirish83033 жыл бұрын

    Beautifully explained

  • @saidasaid9565
    @saidasaid95652 жыл бұрын

    your explanation is the BEST as always! Thank you

  • @EELLmama
    @EELLmama4 жыл бұрын

    Please come teach in my nursing school. You are an amazing teacher!

  • @injustice5991
    @injustice59912 жыл бұрын

    These pharm videos are so helpful!

  • @Cozzie018
    @Cozzie018 Жыл бұрын

    This was brilliant! Thank you!

  • @QAWAZAKI
    @QAWAZAKI Жыл бұрын

    Amazing as always..

  • @meghakadam5404
    @meghakadam5404 Жыл бұрын

    Like the way you have explained in details and step by step , it's helpful in understanding complex topics , thank you for the efforts you have put up , look forward to your videos , also like how you show happiness and interest when narrating , it's like you are having fun teaching and comes through to the viewer .thank you once again.

  • @sueyun375
    @sueyun3753 жыл бұрын

    Great job!! love all your lectures.

  • @Ash-kf1zc
    @Ash-kf1zc3 жыл бұрын

    Thanks for making these, I love learning this stuff

  • @pattycrosby216
    @pattycrosby2163 жыл бұрын

    THIS HELPED ME SO MUCH!!!! Thank youuuu

  • @codyprince7378
    @codyprince7378 Жыл бұрын

    These videos are gold!

  • @vall9588
    @vall95882 жыл бұрын

    You are amazing!!!! You are getting me through acute care NP school! Thank you!

  • @hosinal-hosin9813
    @hosinal-hosin98134 жыл бұрын

    You are just awesome! I am really profiting the whole time from your fantastic videos during my quarantine at home ❤️❤️

  • @sheilawhitney7241
    @sheilawhitney72413 жыл бұрын

    Love your videos! Very informative- thank you!!

  • @buhlemdluli9605
    @buhlemdluli96052 ай бұрын

    You are the best, I like how you explain things a bit by bit. God bless

  • @nilkiani7334
    @nilkiani73344 жыл бұрын

    Perfect as always 👏🏼👏🏼👏🏼👏🏼😍

  • @lilfefeop5856
    @lilfefeop58563 жыл бұрын

    The best explanation overrrr!!!,

  • @sadiank3909
    @sadiank39092 жыл бұрын

    I wish i came across this videos while in pharmacy school, i could have been the best in my set, you make learning so easy and interesting

  • @anshumandhingan6277
    @anshumandhingan62772 жыл бұрын

    Very helpful video. Thank you.

  • @abuadams7947
    @abuadams7947 Жыл бұрын

    Very helpful lecture. Thank you zack

  • @paulastafford1642
    @paulastafford1642 Жыл бұрын

    Awesome as usual

  • @emilyyoung7201
    @emilyyoung72014 ай бұрын

    I love how it’s so easy to follow your videos for my nursing pharmacology class because of my strong A&P 1 and 2 background…that I also acquired through watching Ninja Nerd videos. 😂 Getting me through every part of my degree. 👏 🙌🏻

  • @debbiegoodwin5221
    @debbiegoodwin52212 жыл бұрын

    Great video makes everything so much clearer! Starting my nursing soon and have a feeling i will be on you page alot :))

  • @coolgrl3700
    @coolgrl37002 жыл бұрын

    I love these videos. Best explanation . Thank you!

  • @ritihembrom2551
    @ritihembrom2551Ай бұрын

    I'm very grateful to you and this video😭😭✌🏽

  • @draqsashaikh2595
    @draqsashaikh25952 жыл бұрын

    My God. I hated this topic, but now after your lecture it makes sense, and im loving it❤️ ❤️ ❤️ ❤️. Thankyou so so sooo much😭

  • @evaristokunka3144
    @evaristokunka31443 ай бұрын

    great presentation. Much appreciated!

  • @jibbieoostra
    @jibbieoostra Жыл бұрын

    The best video ever, thank you!!

  • @bhuvaneshwari236
    @bhuvaneshwari236 Жыл бұрын

    You re just amazinggg🤩❤️!!! No words to appreciate ur efforts ✨🔥👏

  • @kamalchandrangari6793
    @kamalchandrangari67933 жыл бұрын

    your lecture are very interesting ,I am many many grateful to you

  • @niazwali8169
    @niazwali81694 жыл бұрын

    thank u so much for uploading such vedio especially cardiovascular pharmacology plus cardiology

  • @dhirubhansali
    @dhirubhansali Жыл бұрын

    Outstanding outstanding outstanding...

  • @sherryjenningsjohnson5414
    @sherryjenningsjohnson5414 Жыл бұрын

    I appreciate your 3 videos: Hypertension, AutoRegulation, and ACE's, ARB,s. You are the best teacher! Looking for more on bilateral renal FMD and direct renin inhibitor, Aliskiren. Thank you.

  • @ropz_karambit1494
    @ropz_karambit1494 Жыл бұрын

    No amount of Thanks will do justice to how much i appreciate your work! i'll donate when i can in the future)

  • @osamamuhammad9096
    @osamamuhammad90963 жыл бұрын

    That was amazing. Thanks a lot ❤️

  • @yachiapatel
    @yachiapatel Жыл бұрын

    Loved when he said "you guys will never forget this mechanism " I literally felt blessed enough by knowing atleast I'm gonna be good at questions with ACE-I & ARBs 😂😂❤🙈

  • @i_reyaa
    @i_reyaa3 жыл бұрын

    Such amazing lectures..!! Finally I can understand medicine

  • @faizanraza8820

    @faizanraza8820

    3 жыл бұрын

    But it is pharmacology 😬😂

  • @roycechen7258
    @roycechen7258 Жыл бұрын

    love your guys stuff!

  • @miman6519
    @miman65193 жыл бұрын

    As Always , excellent video Thank you ❤️🥇

  • @shahabalam3348
    @shahabalam33486 ай бұрын

    Dr zach is doing a very Good job ❤

  • @robertscouten8389
    @robertscouten83892 жыл бұрын

    Great Job!

  • @kcrzn70
    @kcrzn70 Жыл бұрын

    very well explanation indeed! thanks alot

  • @fatmak_af
    @fatmak_af3 жыл бұрын

    Life saver once again!

  • @josiepearce5389
    @josiepearce53892 жыл бұрын

    Excellent tuition .You explain the subject so Well step by step .I look forward to more of your videos and zi will save them all Thank you From U K

  • @ShenoudaRouby
    @ShenoudaRouby3 жыл бұрын

    You are a superstar, mate - I am so fortunate to hit your channel.

  • @floraparvin8210
    @floraparvin82103 жыл бұрын

    Great teacher

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