Pharmacokinetics and Pharmacodynamics

​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

Пікірлер: 102

  • @DirtyMedicine
    @DirtyMedicine2 жыл бұрын

    Please JOIN my KZread membership, where you pay $4.99 a month to support the channel and in exchange you get the cool Dirty Medicine logo which will appear next to your username whenever you comment! Click the "JOIN" button under the video, or click the first link in the description of the video (the one that says "SUPPORT/MEMBERSHIP"). Thanks

  • @kashafjehangirkhan7124

    @kashafjehangirkhan7124

    Жыл бұрын

    How to join the channel

  • @draleenavlogs498

    @draleenavlogs498

    7 ай бұрын

    How to join?

  • @annemarshall752

    @annemarshall752

    7 ай бұрын

    The fee for monthly membership is not 4.99 it's showing 9.99. Is this correct?

  • @MsPriyanka6
    @MsPriyanka62 жыл бұрын

    Hi, I finished my step 1 on July 30 and got 238. I am so happy. Thanks to you atleast i got 10 or more than 10 questions correct only because of dirty medicine videos. Thank you so much 🙏🏻🙏🏻

  • @TravelTherapy022

    @TravelTherapy022

    2 жыл бұрын

    Sounds great 👍

  • @sandhya797

    @sandhya797

    2 жыл бұрын

    Which ones do you recommend?

  • @farooqahmad8044

    @farooqahmad8044

    2 жыл бұрын

    Great yarrrrr

  • @yajayrawalquirialopezmedin5655

    @yajayrawalquirialopezmedin5655

    2 жыл бұрын

    Hi. How was your experience about Step1?

  • @simplex6941

    @simplex6941

    Жыл бұрын

    You think you're smart, how much Tylenol does it take to blow up Albania. I will be waiting.

  • @BaoNguyen-hb9ur
    @BaoNguyen-hb9ur2 жыл бұрын

    I hated this subject so much while in school. The way you’re breaking this dry material down is amazingly good Thank you!

  • @SG-cr2zr
    @SG-cr2zr2 жыл бұрын

    Mnemonic for drugs that follow 0 order kinetics: Zero WATT Power. Zero: 0 order kinetics W: warfarin A: alcohol T: Tolbutamide T: Theophylline Power: Phenytoin

  • @user-ep5pf4hb3q

    @user-ep5pf4hb3q

    18 күн бұрын

    erm, what the sigma?

  • @User-s868
    @User-s8682 жыл бұрын

    I’ve been searching this subject for two days!! Couldn’t find something simple Expecting this to be the answer Thank you

  • @vaishnavishashidhar9686
    @vaishnavishashidhar96862 жыл бұрын

    Thank you so much!!! You’ve made it sooo clear, can’t thank you enough

  • @kpulkit5627
    @kpulkit56272 жыл бұрын

    Ive seen a question solely testing on this same principle that the first part of the elimination graph for 1st order kinetics Is not the elimination but the redistribution itself! Amazing work as usual Dirty !!

  • @givenmichael6177

    @givenmichael6177

    2 жыл бұрын

    He said its distribution

  • @SpeedyMedical
    @SpeedyMedical2 жыл бұрын

    Was tryin to study yesterday, couldn't understand much , thanks for always being there!

  • @videoinformer
    @videoinformer2 жыл бұрын

    One unstated fact that needs to be made clear: Reaching "steady state" requires *repeated* constant doses of the drug being taken, not a mere single dose followed by a number of half-lives. Taking a drug once will result in elimination until it's all gone from the body, never reaching "steady state". Another subtopic worthy of attention is the affect of an initial *"loading dose"* (typically a double dose) on kinetics and attainment of steady state at a serum level that is still determined based on the subsequent regular dose -- *not* based on the loading dose. Naproxen is a familiar nonprescription drug that has label directions that allow for an initial *double* (loading) dose followed by the normal dose at regular intervals of 12 hours.

  • @DirtyMedicine

    @DirtyMedicine

    2 жыл бұрын

    Yes to reach steady state there must be constant dosing, this was implied

  • @Optimization_Coach

    @Optimization_Coach

    2 жыл бұрын

    @@DirtyMedicine Yes it was...

  • @Guidus125

    @Guidus125

    2 жыл бұрын

    I was looking for this comment, because this was indeed not mentioned clearly in the video. Imagine a single dose getting you to steady state and that the level of steady state would depend on the size of the dose... That means if you get high once you would be high till eternity hahaha

  • @StarBuilder222

    @StarBuilder222

    2 жыл бұрын

    This!

  • @itsgonnabeanaurfromme

    @itsgonnabeanaurfromme

    Жыл бұрын

    @@Guidus125 that needed to be explained? He said "you're taking the drug as prescribed", not "you took the drug". These videos are designed for medical students so it is expected people watching would have at least know these things. But it is understandable it may be hard for you if you have no medical background.

  • @DrSajjadPathan
    @DrSajjadPathan2 жыл бұрын

    So Clearly explained. Keep up the good work. Thank you

  • @HenryRph
    @HenryRphАй бұрын

    This was the most instructive insightful easily understandable video on Pharmacokinetics I have ever encountered on video and in Pharmacy school!!!!

  • @nambozohadija3023
    @nambozohadija3023 Жыл бұрын

    What a Wonderful summery. Thanx big, bless u

  • @komaldiptianandmaisuriya4301
    @komaldiptianandmaisuriya4301 Жыл бұрын

    Thank you so much for all your video especially biochem & pharma .you make it all easy . ❤️

  • @chefinwhitecoat
    @chefinwhitecoat2 жыл бұрын

    Just watched the whole thing in one min, I am getting better

  • @Mdepaivaoliveira
    @Mdepaivaoliveira8 ай бұрын

    Great video. Thank you very much

  • @shanthisenthilkumar3831
    @shanthisenthilkumar38312 ай бұрын

    Awesome presentation. Thank u

  • @habakkukwilsonik2740
    @habakkukwilsonik2740 Жыл бұрын

    Wow, Exllent explain 👏👏🤝🤝

  • @darillynn
    @darillynn2 жыл бұрын

    Thank you! Can you please make a video on diuretics?

  • @nesisamoyo6904
    @nesisamoyo69046 ай бұрын

    wonderful stuff keep going, I now know everything about steady state and pharmacokinetics

  • @MuhammadAli-jd2ut
    @MuhammadAli-jd2ut7 ай бұрын

    Appreciate your work 👍.

  • @adityaoruganti9307
    @adityaoruganti93072 жыл бұрын

    Soo needed this at the moment You are a savior angel 🤟

  • @bronxbomma718
    @bronxbomma7184 ай бұрын

    This is the most banal and stale material on the boards. You somehow, found a way to make it pleasant. Kudos.

  • @meimei2630
    @meimei26302 жыл бұрын

    thankkkkk youuu for updates! thank you

  • @xaaboopinkly
    @xaaboopinkly2 жыл бұрын

    Thanks sir!

  • @ambreensabah3758
    @ambreensabah37582 жыл бұрын

    Need of the hour sir

  • @aqsafatima9102
    @aqsafatima91022 жыл бұрын

    Please please dirty make one video on renal pharmacology. I wasn't listening to u before. But i just started with one and it went on. Now i really really feel something missing when doing renal pharmacology. Please make one!

  • @Timtam973
    @Timtam973Ай бұрын

    Amazing lecture!

  • @indiandancey
    @indiandancey2 жыл бұрын

    THANK YOU dirty!!!!!!!!!

  • @niloofarkh4779
    @niloofarkh47792 жыл бұрын

    thank u so much

  • @danielmacedo4417
    @danielmacedo44172 жыл бұрын

    Are those equations about Loading Dose and Maintenance Dose High-Yield for the Step 1 or not that much?

  • @lalitsiriatti1717

    @lalitsiriatti1717

    2 жыл бұрын

    High yield.

  • @pcdihealth
    @pcdihealth4 ай бұрын

    Great Video

  • @rebazothman1506
    @rebazothman15062 жыл бұрын

    Tysm!

  • @jeminiperera
    @jeminiperera6 ай бұрын

    Good one

  • @martinkral7222
    @martinkral72222 жыл бұрын

    Does this apply to vaccines?

  • @Profs17443
    @Profs174438 ай бұрын

    thanks this is really helpful

  • @1412Z
    @1412Z10 ай бұрын

    Thanks!

  • @kmags8065
    @kmags80652 жыл бұрын

    HI this is very useful and informative video ,but what about pharmacodynamics ,do we need to subscribe first to get the rest of the video?

  • @jaxonvictoria4345

    @jaxonvictoria4345

    2 жыл бұрын

    The bulk of pharmacodynamics is pharmacology and all the clinical topics.

  • @onkara4363
    @onkara43635 ай бұрын

    Thank you❤

  • @Nomad278
    @Nomad2786 ай бұрын

    Where can i find a video of Henderson-Hasselbalch equation?

  • @carpe996
    @carpe9964 ай бұрын

    Good lecture overall. Though probably not pertinent to USMLE questions, I would point out though that 1/2 life is NOT the time for which 1/2 the amount of drug is eliminated from the body, but the time needed to cut the the plasma concentration of a drug in half (and those measurements are not the same nor the same amount of time required necessarily ).... A clinically relevant clarification, though, again, maybe not important for USMLE purposes. I am a physician/pharmacist.

  • @Alihaider-he1be

    @Alihaider-he1be

    3 ай бұрын

    Dude, what you are talking about is clearance not half life he explained right

  • @carpe996

    @carpe996

    3 ай бұрын

    @@Alihaider-he1be you have it backwards.

  • @somethingsafoot
    @somethingsafoot2 жыл бұрын

    FOR ALGORITHM TAKE MY POWER I TAKE THIS NEXT SEMESTER

  • @raynaboyarsky4591
    @raynaboyarsky45913 ай бұрын

    thank you !!!!

  • @jonasesenwein3189
    @jonasesenwein31892 жыл бұрын

    Nice

  • @franciszoballah4722
    @franciszoballah4722 Жыл бұрын

    Great

  • @imsuperioroso
    @imsuperioroso2 жыл бұрын

    Nucypher and DOGEcoin to the MOON! 🚀🚀🚀

  • @Vunami

    @Vunami

    2 жыл бұрын

    sir stop talking about crypto in a medical channel

  • @imsuperioroso

    @imsuperioroso

    2 жыл бұрын

    @@Vunami med students have student loans to pay and investing may help pay them off sooner

  • @plutobaby9996
    @plutobaby9996 Жыл бұрын

    this video is so clutch

  • @jaymata1218
    @jaymata121810 ай бұрын

    11:03... thank you kind sir

  • @jaehaerys9194
    @jaehaerys91942 жыл бұрын

    300likes... i am not going to ruin it by clicking it... but i really do like the video

  • @annemarshall752
    @annemarshall7527 ай бұрын

    The fee for monthly membership is not 4.99 it's showing 9.99. Is this correct?

  • @smallpharm13450
    @smallpharm134502 жыл бұрын

    OK sir

  • @alimahmoud9334
    @alimahmoud93342 жыл бұрын

    good

  • @abdu170
    @abdu1702 жыл бұрын

    Thank you very much!

  • @nuckchorris1396
    @nuckchorris13969 ай бұрын

    U the best

  • @user-fv8cr7zz2c
    @user-fv8cr7zz2c3 ай бұрын

    Powerful

  • @SalmaSaifuddin
    @SalmaSaifuddin10 ай бұрын

    i wish i could send you my tuition money instead of giving it to my school

  • @DrUsamaCh98
    @DrUsamaCh98 Жыл бұрын

    👍

  • @drismail469
    @drismail4692 жыл бұрын

    thank you so much

  • @medicallife3738
    @medicallife37382 жыл бұрын

    Hey dirty please make video on pprf lesion

  • @tubby7817
    @tubby78172 жыл бұрын

    For algorithm

  • @joshmcgoo
    @joshmcgoo2 жыл бұрын

    COMMENTING FOR THE LGORITHM

  • @alvaro37nf
    @alvaro37nf2 жыл бұрын

    Dirty, what is your opinion about AMBOSS?

  • @DirtyMedicine

    @DirtyMedicine

    2 жыл бұрын

    my opinion is that its okay to use but that I think UW is better if you have to pick one

  • @alvaro37nf

    @alvaro37nf

    2 жыл бұрын

    @@DirtyMedicine thank you for your response!

  • @ekanki07

    @ekanki07

    2 жыл бұрын

    @@DirtyMedicine How essential do you feel Boards and Beyond is to Step 1 Study? (if using UW and your videos)

  • @hritvikjain__3594
    @hritvikjain__35942 жыл бұрын

    commenting down here for the algorithm

  • @user-js8nu6gu1i
    @user-js8nu6gu1i8 ай бұрын

  • @nafissajid1
    @nafissajid1 Жыл бұрын

    🎉😅❤

  • @TheSharan12
    @TheSharan1215 күн бұрын

    good lecture and a better understanding thank you will continue watching your pharmacology lecture please subscribe to this channel

  • @Physiciansdesk
    @Physiciansdesk2 жыл бұрын

    Aspirin phenytoin and …? Zero order ! Answer

  • @TheSharan12
    @TheSharan1215 күн бұрын

    ss

  • @yeyo101
    @yeyo1012 жыл бұрын

    1 day too late

  • @medizinundnatur1494
    @medizinundnatur14942 жыл бұрын

    Please change the name of the channel. There is no dirt in medicine