I love how you just spit it out. I can't stand when someone take forever to say something. Great video.

@joalexsg9741

5 жыл бұрын

The problem is that, for the majority of people, this is way too fast to grasp the content as due, especially if one is not acquainted with the terms or has graduated from another area but not necessarily either as in such a brief span of time it's not pedagogically fit to make a person fix the processes in the mind! I say that as an educator myself, who, though retired, loves learning about different subject and helping those who are also interested in this sort of learning. The platform Future Learn gives wonderful online courses on an incredible diversity of areas and topics, many of which target the lay public (and/or students looking for a career to follow when they get into college). I actually watched this as one of the videos suggested by one of the courses I made there recently. Each university also makes videos of their own for the courses but which can only be accessed on the course pages.

@mayi.matysik6332

3 жыл бұрын

@@joalexsg9741 so watch it a few times. He explains and shows everything he is talking about.

@joalexsg9741

3 жыл бұрын

@@mayi.matysik6332 Have you ever considered that people must have other subject as important as or even having more priority over to focus on? I could grasp if but I often have too many ongoing readings (and many more in line) and videos from different topics and areas to watch as well. I advise those who are engaged in pedagogical initiatives to use the modern techniques taught by the latest advances in neuroscience applied to teaching and learning: cutting the info in smaller chunks so the brain can assimilate them better and stick to the essential points in each process, if a larger audience is targeted. This is the best for reaching a larger public which has not studied any subject in the area but wants to get acquainted with it, unless the educator is only aiming at the specialized public. However, even in the latter case, if one is worried about helping those with more difficult in learning, for whatever reasons, such techniques are also required.

@curtisjackson5793

2 жыл бұрын

@@mayi.matysik6332 don't you think that the process of rewatching a few times and actually thinking about the video in order to really grasp the content is somewhat similar to a relatively slower method of teaching/passing along the information? In other words, the outcome is more than less the same, at least the time and effort required.

@rashoietolan3047

2 жыл бұрын

Laughs hypercognitively in x3 speed Once is more then enough

This channel is amazing. My teachers take hours to make messy and completely not understandable something what you can make clear in two minutes!

@junkyardwillie8320

3 жыл бұрын

I have a younger sister who’s teacher actually use this video in her lesson

@rashoietolan3047

2 жыл бұрын

It’s a Paragon of brilliance to be able to simplify the complex Just as cooking our food with heat made it easier to digest in shorter time frames thus leading to greater psychic evolution

It should be illegal to make an ad that's longer than the video itself

@squash843

4 жыл бұрын

😂😂😂😂😂

@seth.czerepak

3 жыл бұрын

Ads are the price you pay for getting free content. So, stop whining.

@dslivelocalrockstarsmactmu3529

Жыл бұрын

I so agree 👏🏻

@TXRoeJogan

10 ай бұрын

@@seth.czerepak there used to be no ads at all on KZread

It always stuns me to see how concepts can be further broken down into simpler and simpler terms, making the complex into the the bread and butter. Excellent work!

very underrated video (and likely channel). Extremely well presented in an incredibly concise way. I love it!

This short topic description is absolutely perfect for quick understanding ❤️

I'm from Brazil and I love studying english medical content because of its easy explanation. Congratulations!

Singlehandedly both igniting my passion towards neuroscience, but also saving me from the wrath that is my finals in a week. Much love

@farhanaumeer

Жыл бұрын

I know that feeling! Did you know some addicts use loperamide in oder to get high? To cross the blood brain barrier with antidiarrhoeal medication...now that's what I call talking sh*t!

A 2 minute process that clearly explains blood brain barrier thank you.

Thank you so much! I just could not get this concept to click on how it was structured or functioned and this simple explanation at least gives me an idea of what is meant when the bbb is referenced. Thank you.

Thanks man !! Really helpful . Love the quickness

With the astrocyte ends touching the endothelial tissue around the vessel, that explains how brains react to various substances that might slip between the endothelial tissue, such as ETOH. Thank you so much!

Thank you. To the point.👏👏👏

Great video, thanks!

Nice job young scientist, thank you for posting, keep learning and keep teaching (two great ways to expand knowledge)!

Thank you my life savor!

Absolute legend

I'm very grateful!

thank you! we're now studying physiology so i am looking for vids related to it.

It's really helpful..thank you😊

very nice video with great explanation

Blood brain barrier : blood brain barrier is a complex that separates the brain blood veels and the extracellular fluid in the brain. It is endothelial cells that surround blood vessels and has gaps in it so it can let certain molecules in or out of blood vessel into the brain . These substances can include caffeine, Glucose, alcohol but not include drugs this is why brain medicine is hard because of it permeability it does not let its effects take place .

These videos are perfect! Just the right amount of information to get going and read thru my textbook. Thank you =)

Loved it! Can you do a blood CSF barrier video?

brilliant mate

Thank you 😀 😊

Tomorrow is my Final exam and I have learned alot form this.Thank you Sir😊🙏

Great video. Can you go into more detail about brain endothelial cells?

Thank you

this is amazing

Good Job :)

Love it!! Thank you!

Great🌟

Thank you.

I appreciate your work. Do you know of what substances/foods one would want to avoid to maintain a healthy BBB? For example, sunscreen.

This is great, but I have a question. What is that greyish brown cell between the astrocytic end-feet and the endothelial cells? The endothelial cells, with their basement membrane, ARE the wall of a capillary. Capillaries are the vessels where exchange with the interstitial fluid would be happening, so they are the relevant vessel when we are talking about a blood-brain barrier. There wouldn't be a cell type in between the astrocytic end feet and the endothelial cells in capillaries, would there? thanks.

@neurochallenged

2 жыл бұрын

Hi, the brownish layer is supposed to be the basement membrane, and the cell you can see embedded in there is a pericyte. Pericytes are embedded in the basement membrane, so they would be found between the endothelial cells and astrocytic end-feet.

In 2016 I nearly died from infections in my head that spread to my brain. Sinusitis, cellulitis, sepsis and meningitis. This caused a blood clot and the narrowing of an artery. I had another scan recently and had an appointment today to discuss the results. The artery has completely closed up and need another scan to make sure all the parts of my brain are getting enough blood flow. The doctor told me about it assuring me that it will most likely be fine, but I still don't really understand. If one of the arteries blocks off, will it redirect to the rest of my brain? I am very worried about this.

Very good sir

can u make a vid about designer drugs? thanks

Considering the BBB's function, how are drugs able to alter my state of mind?

@neurochallenged

4 жыл бұрын

Drugs that affect the brain typically have qualities that allow them to pass the BBB: 1) They are very small, which enables them to pass through the tight junctions of the cells that make up the BBB, and 2) They are lipid (fat) soluble, which enables them to pass through the astrocytic end-feet that make up the BBB. These qualities enable drugs to pass from the blood into the brain.

@feynstein1004

4 жыл бұрын

Exact same thought I had lol

@clydellemaebarrientos6152

3 жыл бұрын

what are examples of these drugs? #interruptingforknowledge hehe

Brilliant wee channel Belfast Ireland 🇮🇪 😎

Very beautiful sweet video

Would you be able to tell me which sources you used to make this video?

@neurochallenged

7 жыл бұрын

Most of it should be able to be found in any neuro textbook, but here is a paper I used for this video: Ballabh P, Braun A, & Nedergaard M (2004). The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiology of disease, 16 (1), 1-13 PMID: 15207256

@mayi.matysik6332

3 жыл бұрын

@@neurochallenged so this could happen with what they put in the covid shot?

Nice

Can the covid19 swab damage the blood brain barrier.. What could it do.

Can you do a video on the covid19 swab test so we can see how far it goes into the blood brain barrier if it does.

@neurochallenged

4 жыл бұрын

A COVID-19 test swab isn't getting close to the blood-brain barrier.

@lealea7329

4 жыл бұрын

@@neurochallenged ok.. Thank you for answering so fast..

@kevinvaladez6432

3 жыл бұрын

@@neurochallenged Welp, theres evidence now that COVID-19 has the ability to pass through the blood brain barrier

@mayi.matysik6332

3 жыл бұрын

@@kevinvaladez6432 that's one of the reasons I won't be getting that shot.

Wow 🤗

How bacteria and viruses cross this tight junction of BBB? Which type of herbal medicine can cross BBB? Medicated oil applied on the scalp skin can provide herbal medicine to brain through blood vessels by crossing BBB? Please Answer.

@neurochallenged

6 жыл бұрын

Anything that can get into the bloodstream has the potential to cross the BBB if it has certain characteristics (e.g. lipophilic, very small). The active ingredients of some herbal medicines certainly have those characteristics. Same thing with a topical medication---it's possible if it contains ingredients that are small and lipophilic and can be absorbed transdermally into the bloodstream. But it all just depends on the characteristics of the substance.

@stevmill6041

5 жыл бұрын

Try dmso along with herbal medicine. I usually use mms with dmso. I learnt that it crosses bbb

I feel like I'm gonna pass because of your videos. Thank you

طيب ليش ما في ترجمه للغه العربيه

1 minute neuroscience, amiright? #x2

@grieftick

4 жыл бұрын

how did you know lol

Do the circumventricular organs have "typical" blood vessels?

@neurochallenged

4 жыл бұрын

Yes, they're just more permeable than those found in most of the rest of the brain.

@birage9885

3 жыл бұрын

@@neurochallenged So the, they would be the glands more susceptible to heavy metal toxicity in the brain, correct? Other than the posterior pituitary gland, what other glands make up that area?

Génesis 1:6-8…. The CSF barrier is the firmament within us 🙌🏾💯💙

Posterior pituitary gland is like the gate keeper to pathogens entering the brain

@feynstein1004

4 жыл бұрын

Damn m8 😂

This is what they are poking through during those "tests".

How to watch this video? 0.75x speed ! :)

So after watching this video and looking at your subscriber count, I went to compare this video to some of the bigger educational channels: asapscience, minute physics, vsauce, etc. And I found that almost all of their videos had included some small, barely noticeable , background music. I think it helped balance the video in some way and made it more engaging. Idk why but its incredibly effective. Maybe try adding some low, royalty free music, to your videos and I think you'll find it will make a big big difference with audience retention, watch time, etc. Another thing I noticed with the bigger channels is the speaker often changes their pitch and tone throughout the video which allows otherwise boring content to seem more interesting. Your speech is somewhat monotone, like you're reading off of a card. I think if you take a more conversational approach the video would be more engaging. Just some things I thought I'd point out! :) Please please don't take my comments as something coming from ill will or malicious intent, I simply thought I would give you some tips. I wish you only the best with your channel! 👍

@omyelia

6 жыл бұрын

Mr. Creasy I think the main diff between these videos and the more popular channels is that their videos are often longer than 2 minutes, so you have to be more engaging to hold attention. However, with so much info presented in 2 minutes, I’m really focused on every word that’s being said and I think any music could detract from that.

@sherischneider2672

5 жыл бұрын

Simple, short, and super clear video. The only change needed might be to add one minute and to leave 15 seconds to finish the thought stream. I would still have watched it at 3 minutes.

Can the coronavirus test pierce the blood brain barrier?

@neurochallenged

3 жыл бұрын

No, it cannot.

God is so incredible!

Water is not lipid-soluble. how it's gonna pass?

@neurochallenged

3 жыл бұрын

The mechanisms of water passing across the BBB are not fully understood, but it does pass relatively easily. One way water seems to be able to pass is through aquaporins, which are protein channels that help water to pass in and out of cells. But aquaporins alone don't seem to explain how easily water can pass the BBB; there are likely other mechanism (e.g., active transport) involved as well.

Still have to watch it about 5 times over. Why not take your time and explain it a little better. Things like this really shouldn't be rushed.

it's just another confirmation that God exists❤

Sado fetish

You should make it 4 minute instead. You're speaking too fast and animation looks sped up

@Trovatore75

7 жыл бұрын

You can record it and play back at half speed ;)

@snozzmcberry2366

7 жыл бұрын

You can do that directly in the player (maybe not on mobile)

You speak too quick to understand) 3 minutes will be also ok)

@SuperZootman

8 жыл бұрын

+Elena Muslimova Change the video speed.

@Dumbpuppet101

8 жыл бұрын

could just turn on the captions, pause the video every few sentences and read at your own pace. its a two minute challenge for a reason :-)

@joalexsg9741

5 жыл бұрын

So, this is advocating the law of the wittier, a variant of the law of the stronger Besides, it's not a good argument in pedagogical terms either cause shoehorning complex process into 2-minute videos is not pedagogical at all!

@madisonc8785

5 жыл бұрын

lol turn on captions

@antiignorance2245

4 жыл бұрын

Turn on captions and adjust the playback speed

talking too fast won't make it easy for me to understand.

@feynstein1004

4 жыл бұрын

There's a playback speed button in the settings, mate. You can use it to slow down the video if it's too fast for you.

still too much information per second. It's great the video is 2min, but most ppl will just replay it a few times.

Poor guy, his voice is full of tiredness and exhaustion

Ur too fast

Jesus, can you talk any faster? All I heard was "..... 2 minute......". No wonder kids find edumaction so difficult these days. Everyones in a rush.