The Pharmacogenomics Knowledgebase (PharmGKB) collects, curates and disseminates knowledge about the impact of human genetic variation on drug response (pharmacogenomics).
Please note that PharmGKB is a research organization and, as such, is unable to offer clinical advice.
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WOW!
Evil eugenicists.
Getting the following error while executing the command - python preprocessor/pharmcat_vcf_preprocessor.py -vcf pharmcat_positions_2.8.2.vcf File "preprocessor/pharmcat_vcf_preprocessor.py", line 103 script_dir: Path = Path(globals().get("__file__", "./_")).absolute().parent ^ SyntaxError: invalid syntax
For help, please open an issue at github.com/PharmGKB/PharmCAT. You will also need to provide more information. For example, version of python are you using?
I love the information you're sharing here. Do you have any videos or good reading material on star alleles?
Edit* found it. Thanks for the supporting video in the header!
Interesting.
The bit about transparency, like you say is so critical!
Hello Thank you for the tutorial. But The pharmcat-2.8.2-all.jar file does not exist github anymore. Is there any alternative to this part of the pipeline? has something changed in Pharmact pipeline? I really appreciate if you can guide me on this matter.
All releases are available on GitHub. Make sure you click on the "Releases" link instead of a specific version. Here's a direct link to 2.8.2: github.com/PharmGKB/PharmCAT/releases/tag/v2.8.2
Excellent video well done
G-L660 is my Haplotype. Does this mean my actual lineage? My ancestral line?
Thank you so much for this awesome video. Started taking clomipramine 3 days ago and developed serotonin syndrome and bunch of unpleasant side effects. My psychiatrist gave me the normal starting dose of 25 mg/day but I feel like I’m dying. This explains a lot
amazinggg
Veadeo hindi me ❤
Amazing lecture.. 👏🏻 . But volume is low... resolve this issue.. difficult to hear 😞
Tast ka prige
Mam is sa pura pata cal jata haii gilbad haii ya nahi
WHY?! Did an insane person create this nomenclature? It seems idiotic.
Outstanding information, very comprehensive and clear - thank you very much!
I am normal metalbolizer and i started 50mg azoran and after 4weeks WBC reduces from 5800-3900 i stopped ,i am suffering from cronhs disease what are option available to maintain remission
Great talk👍
Thank you for the wonderful talk and for sharing your experience! It was really motivating and covered mostly all aspects of academia.
Thanks for recording and posting!
Thank you for this truly excellent summary of the PGx resources!
Hey!!! How you have made your first slide transition? Can you please tell me,
it is done with the help of morph transition
💥 𝕡𝕣𝕠𝕞𝕠𝕤𝕞
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One of the same enzymes that metabolises THC
Even with cyp2d6 inhibitors like fluoxetine codeine still has some effect even if its mainly from codeine 6 glucoranide as opposed to morphine but obviously its relative potency is reduced relative to extensive and ultrarapid metabolisers.
👀
Thank you for useful summaries! They are great!
I’m really looking forward to coming and working in your great lab!
These are amazing free resources. Such a wealth of information. Thank you for standardizing and maintaining those data displays with consistent harmonized structure.
Ads off
All thanks to doctor Aba for curing me from HIV am forever grateful sir
Free Cedric Millage
What you are listening to now by Dr Hampikian
Dr Hampikian allowed his forensic science friends to talk about Y-STR standard s thay was not reliable.Free cedric millage.
You place everything revolves around you, stupud.
Why so hurry to speak, are you trying to impress us about your speed reading, dpeaking?
Very informative thx
I ❤️ Carole! She rocks!
I am coming
What's that even mean lol
please I need helpe i'm reading some articles concerning CYP2D6 and i found that in some cases when genotyping CYP2D6 some persons have sevral diplotype in CYP2D6 and I don't understand the process and can that exist ? for exp i find a person with this genotype ( *1/*1 - *1XN/*5 ) and I didn't understand I should considred him as an Extensive Metaboliser or Ultra rapid ?? and why he gote 2 genotype ?? the first is for the maternal chromosome and the second for the paternal chromosome ..??? please I need an answer.. thank's
Kerry Robinson, the prisoner mentioned in this talk was freed the day after this conference. He had spent 17 years in prison. He was freed by math and DNA.
Thank you for approaching complex issues so simply, concisely and with gentle humor. You poke holes in beliefs and allow light to flow. Lovely. You have helped me understand more clearly what to explore in what we are putting in place here in our Nature-based educational approach here at Another Way School for children - Native and nonnative.
Sir medicine o. UGT1A1 for normal bilirubin metabolism
aap tast karbaiya haii
Fantastic talk that covers a lot of ground and lives up to its title. Even ends with a question on #MeTooSTEM and the advice to NIH to make harassers ineligible for training grants (a no-brainer).
FREAKING AMAZING!!!
😢😮
So if I understood correctly they can cut out chunks of RNA but they cannot add them yet. Is that right?
This technique is very awrsum scientific break thought but i have a lot of question and ethical problem with it because if its going to be authorized to human application companies which will be using it can edit human embryo to do a lot of genetic changes that get get out of control in the future.This will produce a new generation of genetic modified human which can facilitate a man made human evolution.Again who is gonna authorize which genes should be edited and on what condition and another thing is money ,only rich people will be able to edit their genes and they wont die or get sick .
but still we don't know about our DNA so lts still ambitous.So we still cannot apply it to people.