This is a summary of the CPIC guideline for serotonin reuptake inhibitors and variation in the genes CYP2D6, CYP2C19, CYP2B6, HTR2A and SLC6A4.
This video will focus on the recommendations for citalopram and escitalopram. Videos covering the recommendations for other gene-drug pairs as well as a video about the gene-drug pairs with no recommendation in the guideline can be found at the following links:
Fluvoxamine and CYP2D6 - • CPIC guideline for flu...
Paroxetine and CYP2D6 - • CPIC guideline for par...
Sertraline and CYP2C19, CYP2B6 - • CPIC guideline for ser...
Venlafaxine and CYP2D6 - • CPIC guideline for ven...
Vortioxetine and CYP2D6 - • CPIC guideline for vor...
Serotonin reuptake inhibitors and CYP2D6, HTR2A and SLC6A4 (no recommendations) - • CPIC guideline for ser...
Guideline and supplemental information - cpicpgx.org/gu...
Annotated guideline and genotype picker - www.pharmgkb.o...
PharmGKB citalopram and escitalopram pathway - www.pharmgkb.o...
CYP2C19 Gene Information Tables - www.pharmgkb.o...
PharmVar - www.pharmvar.org/