Why SGLT2 Inhibitors Cause Euglycemic DKA

Why are we seeing so much more euglycemic DKA after the introduction of SGLT2 inhibitors? In this video I will go over why so many more Type 2 diabetic patients are coming in with DKA when this disease process was previously much more predominantly seen in Type 1 diabetic patients. I will briefly review the pathophysiology of DKA (it's a helpful thing to review imo!) and then we will see how SGLT2 inhibitors end up playing a role to create a relative insulin deficiency leading to euglycemic DKA!
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Пікірлер: 26

  • @chloesmombetsey
    @chloesmombetsey

    Currently hospitalized from this. Thank you for the clear explanation.

  • @rosedean-paccagnella5820
    @rosedean-paccagnella5820

    Nice paintings too! thanks for the explanation

  • @bfurl69
    @bfurl69 Жыл бұрын

    Great video. I’m giving a presentation tomorrow on outpatient T2 diabetic meds and I got to SGLT2 inhibitors and scratched my head at euglycemic dka. Hopefully i can avoid getting pimp slapped tomorrow! 😅

  • @nina-cy5dd
    @nina-cy5dd

    second year med trying to refresh on this stuff before my endocrine block. thank you! you explained that so well

  • @ericaaguilar6537
    @ericaaguilar6537

    Ambulatory care pharmacist resident here who is going to be presenting on weather we should or should not re-initiate SGLT2i post eDKA/DKA in patients! Appreciate the clear explanation for the mechanism :D

  • @chrissem2654
    @chrissem2654

    Thank you for the detailed explanation. This explanation is very helpful to understand what is going on in my body. I have just been diagnosed with EDKA caused by Synjardy to treat Prednisone indused high hba1c, which made me very sick to be admitted to the ICU. I was never a diabetic, the doctors checked my blood work for 2 years back, and there was no indication that I ever had diabetes, so the EDKA was cased by Synjardy. Thank you so much. New subscriber watching you from 🇨🇦 🇨🇦 🙏❤️

  • @debigdogk9563
    @debigdogk9563

    Great explanation, it finally makes sense. Thanks Conan ❤❤❤❤

  • @irrelephant0
    @irrelephant0 Жыл бұрын

    Really helpful! And always nice to review a little bit about DKA - I tend to always forget about it haha

  • @chelseahylton2478
    @chelseahylton2478 Жыл бұрын

    Extremely helpful!!!!!

  • @javadaghrab5687
    @javadaghrab5687

    Fantastic information I have been looking for this kind of a concise and to the point answer most of the time I get bulshit for HELP.

  • @malsam9668
    @malsam9668

    Thank you, very helpful. Watching this at my sisters bedside as she is in ICU with this now. She was on Jardiance.

  • @SourChip123
    @SourChip123 Жыл бұрын

    As an M1, its cool listening to you talk through these topics. Do you think you would ever make a video highlighting paths to different fellowships after IM?

  • @tiffanytran4970
    @tiffanytran4970 Жыл бұрын

    Could you do a video on DKA/HHS management please? :) thank you!

  • @user-tu5oy4zk4x
    @user-tu5oy4zk4x

    well explained

  • @annaohare8263
    @annaohare8263

    Thanks helpful, from a nurse .

  • @bruryrosally-dq9qw
    @bruryrosally-dq9qw

    most article prefer the term "classical" DKA, some might prefer "typical" DKA rather than "normal DKA" to describe the most common type of DKA

  • @davidalex1506
    @davidalex1506 Жыл бұрын

    Inability to complete cellular respiration

  • @MysticMango412
    @MysticMango412

    Hi, I was wondering which stylus and trackpad you're using for this video.

  • @LEARNING-MEDICAL-EDUCATION
    @LEARNING-MEDICAL-EDUCATION Жыл бұрын

    dear doctor, lets solve some drug add and abstract questions from ABIM

  • @BsmLy
    @BsmLy Жыл бұрын

    Is it possible to have EDKA although taking NO medication whatsoever?