This is the longest Paul has gone with a shirt on

LDL does not directly cause atherosclerosis. 2 obvious reasons why: 1. Atherosclerosis occurs soley in arteries, despite the fact that the veins carry the same LDL as the arteries and we don't get atherosclerosis in veins. 2. Atherosclerotic plaques occur in very predictable regions in the arterial tree (near bifurcations/branches). If LDL was causal, it would develop uniformly across the arterial surface and it doesn’t.

Paul only references his own situation and doesnt seem to acknowledge everyone is different. Then continues to laugh in a smug way as if Derek's input is inferior.

@JohnSmith-zs1bf

2 ай бұрын

Not true. He has debates on his channel where he goes over literature with conventional doctors.

@zirzmokealot4600

2 ай бұрын

@@JohnSmith-zs1bf I was referring to the conversation with Derek

@JohnSmith-zs1bf

2 ай бұрын

@@zirzmokealot4600 is the whole conversation out? doesn't look like derek asked for an explanation in this clip, just conclusions. i think he's laughing to be polite instead of aggressive. derek wasn't even giving input he was literally asking questions. "even if x?" "even if y?" "So say xyz and then abc, would you still?" Derek didn't even make any direct statements, although he was pushy which I like, i think you're taking it out of context and attributing malice where there is none. Paul is used to being doubted on his claims but I've seen him back up a lot of his stuff when he has the time to.

@zirzmokealot4600

2 ай бұрын

@@JohnSmith-zs1bf i think one thing and you think another. Is that ok that I read the conversation differently. Paul is biased in my opinion. Because he directly relates everything to his situation. Paul had a nervous smug laugh imo because his opinion was being challenged.

@JohnSmith-zs1bf

2 ай бұрын

@@zirzmokealot4600 I think he just recognizes that point of view. I agree we have different viewpoints, don't really need to clarify that. I'm just trying to add some context and defend the guy from allegations based on your interpretation of his "type" of laughter, based on more concrete evidence and context. If you don't like him that's fine I just don't think it's right to cast aspersions based on your bias and a selectively cropped clip. How much are you going to read into a giggle? If you've seen Paul's context you can see that he's very willing to talk about things and have his mind changed. I think he's probably laughing because he's talked about that exact topic a million times and can explain himself but Derek is machine gunning question after question without asking why. It's like Derek is trying to get Paul to say he would use medication in one extreme example, but Paul wants to expand on the opposite point, that the medications are likely not as effective as it seems and has more downsides than meets the eyes. I like both of these guys, clearly different points of view. It's immature to look at a clip like this and make such a broad statement about someone's character because you think you're some kind of body language expert, when you can *actually* find out what he thinks by listening to what he *actually* says instead of trying to psychoanalyze him based on a clip from your favorite youtuber.

As a board certified family medicine doctor, I'm almost always the first and only guy to prescribe treatments to patients with hyperlipidemia and/or insulin resistance. I can tell you with utter certainty that Paul could not hang in a conversation involving other doctors. Derek does as good as anyone could considering he's not a doctor (although he's a bit tied up in the rarities and very minor details, e.g., ApoB and LPa). Regardless, it is patently obvious that in a room full of doctors Paul would sound like a baboon. He answers hypothetical questions by asking for hypothetical specifics... or he just talks about himself? An informed doc would cite nuances of data, standards, exceptions, NNT and NNH, forks in the decision-making algorithm, etc. They wouldn't be talking about their own LDL levels.

@PiccoloSolos

2 ай бұрын

so would you, based on your experience, agree with Derek?

@animalbasedguy9488

2 ай бұрын

Stupid comment since Paul has debated a well respected cardiologists on this subject and it didn't go well for the cardiologist.

@kurtyaz

2 ай бұрын

Yeah this is nonsense- Paul has debated countless MDs and “experts,” they almost always get destroyed by Dr. Saladino when he has prepared studies and asks them about their studies they reference which are almost always not well outlined. Also the fact that you hold such a strong bias in your statement without even looking into the above fact just goes to show how lazy and/or ill informed most doctors are these days at keeping up with understanding wellness. A large majority doctors get a degree, do little education after and are heavily influenced by pharma to treat symptoms and process their clients, the system is broken and though many are good intentioned it’s backwards and the results ultimately speak for themselves with how sick America is and how many drugs we prescribe people. Ironically Paul might sound out there, but there’s a reason 80% of the population is America is sick and a lot of docs just don’t have the resources or incentives to treat their root cause underlying health conditions.

@flochfitness

2 ай бұрын

Appreciate your perspective 💪🏻

@sithounetsith9877

2 ай бұрын

You are here to prescribe drugs for big pharma, you are not here to think lol

He has returned 💯

Ok, so where is the whole podcast?

This is just what I needed

Salad is pretty combative isn't he? When you get to the "define the meaning of the word 'is'" phase, you know what the actual answer is, you just have an ideological need to not admit it

@animalbasedguy9488

2 ай бұрын

Your comment is astronomically stupid.

@flochfitness

2 ай бұрын

Yeah. You don’t see experts who know their shit and who are backed by actual studies and facts having to resort to rhetoric like this.

After a hiatus, Derek is back dropping videos like Kendrick dropping diss tracks…

@toddmarkarian9665

2 ай бұрын

He was just training and expanding his knowledge base... I think he came back smarter

@TheUnemployedGoku

2 ай бұрын

@@toddmarkarian9665 he was already smart... now he is just rich about it.

The king is back 👑 How long until more funny true stories about tren?

My ldl is 235 and I'm not taking anything

@Lucas_Jeffrey

2 ай бұрын

good for you. maybe at least get set up with a CT angiogram at some point. If u have no plaque then why bother worrying about high cholesterol.

@akosiryan9761

2 ай бұрын

@@tennsound I'm sure your doctor was surprised like mine and suggested a "super statin.

I could maybe be talked into trying a PCSK9 inhibitor if the price of those comes down a lot, but I'm absolutely not taking a statin for primary prevention.

is this health and fitness?

Paul was repeating Derek's words back to him to make his vocabulary seem on the same level. Lol

@_________9996

2 ай бұрын

He actually has quite a good vocabulary, but uses it to obfuscate some really poor ideas

@pricklycats

2 ай бұрын

Nah that’s called basic communication skills. If you take any communication course that’s one of the first things they teach you. Repeat what someone said to you to confirm that you heard them correctly. You have a pessimist bias and you need to work on that flaw in your personality.

@pricklycats

2 ай бұрын

I don’t even know who he is I’m not a fan but you’re clearly trying to find the worst possible interpretation of his intent you can muster and it’s pretty pathetic

@MarkVirgulto

2 ай бұрын

@@pricklycats you took one observation I made and come to the assumption that I need to work on a personality flaw? You must be one of those special types. Bless your heart.

@hansel7888

2 ай бұрын

​@@MarkVirgultono, no watch the video again

it's probably better to hedge against atherosclerosis with at least a PCSK9i or something else with low sides. After all, most good data we have suggests high LDL is linked to heart disease.

@flochfitness

2 ай бұрын

Correct. But Paul’s shtick is to talk about mechanisms as though they are the answer. Mechanisms mean nothing compared to outcomes. When you look at HRCT the information is fairly clear on this subject.

@Lucas_Jeffrey

2 ай бұрын

I've seen a meta-analysis about statins that shows low doses have almost the same effect as mega doses. That's another way to hedge against ASCVD with low sides, if the $450/month repatha is not something you can afford or have covered by insurance.

Paul Wordsaladino thinks that if he talks fast enough with enough scientific terms he'll get away with the dumb and dangerous shit he says. Man picked the wrong podcast...

@SaturnReturns

2 ай бұрын

Why would someone need to take pills if they're perfectly healthy? Especially pills that have side effects and can lead to other health conditions down the road like dementia.

@the_notorious_bas

2 ай бұрын

Yeah, I don't understand why Derrek said yes to his invite.

@byrnetree

2 ай бұрын

paul loves mechanistic bolloxology

@morpheus9281

2 ай бұрын

What is he saying that’s dumb and dangerous?

@the_notorious_bas

2 ай бұрын

@@morpheus9281 Preaching the carnivore 'lifestyle' and demonizing vegetables is pretty dumb and dangerous, yes.

Upload the entire podcast Derek. Sick of these clips.

All the doctors in the comment section, should I take statins/ezetimibe/pcsk9 inhibitor etc?Just got my blood work back a week ago, and have been researching and thinking about this for the past week. I am in the exact camp as what was being described in this video: High apob (125), HIgh LDL, low HDL, very low triglyceride, good thyroid function, metabolically healthy, very health lifestyle.

I want to look into it more but I think metformin is one of these drugs that fall into this category that is being explored further as more of a prophylactic drug before the onset of diabetes. As far as lipid lowering drugs go I don’t think it makes sense unless they have a high ascvd risk score.

This is an interesting discussion. Would love to hear the entire thing.

@LowkeyLukeDnB

2 ай бұрын

Derek said full video coming Wednesday (tomorrow)

Oh oh oh Ozempic

Wow, I wish I knew what was being said. I’m going back to school

“It’s probably only justifiable if I’m selling a scam product that covers it. Take sunscreen for instance. You can find multiple videos of mine trashing sunscreen, but now that I have a tallow based sunscreen, it’s vital for humans to protect themselves from the sun! I make sure to wear it while I surf and walk to the market in my Costa Rican home town!” - Paul Saladino

Genotype 3/4 if I live a healthy life no accidents I will die of cardiovascular disease.

@kennyoffhenny

2 ай бұрын

Huh?

@toddmarkarian9665

2 ай бұрын

​@kennyoffhenny he has the gene for heart disease. It's effect will eventually be his death, at some point

@Therav1

2 ай бұрын

@@kennyoffhenny Todds right

@Therav1

2 ай бұрын

@@toddmarkarian9665 Thanks for explaining

This guy is pretty ridiculous and Derek knows it. Can’t wait for him to amend his views yet again after he discovers atherosclerosis development

Derek wearing an outdoor lumberjack button-down flannel while ps wearing a T shirt...wht the fk is going on?

@animalbasedguy9488

2 ай бұрын

Bodybuilders have a tendency to hide their body when they don't feel in shape or as bug as they use to be. Not hating, it's just how it is.

@animalbasedguy9488

2 ай бұрын

*big

@olathecola7691

2 ай бұрын

@@animalbasedguy9488Then again flannel clothing has been a trend in fitness fashion for 5 years now

Derek trying so hard to not come off condescending

I understand keeping statins as a last resort and I wouldn't deploy them in his situation, either. However, ezeitmibe and PCSK9Is are nearly side effect free.

Just say "NO"

Plate and Paul.

We all missed you daddy, hope the daily vids are back

Paul Saladino is doing real damage to people when he says he wouldn’t recommend statins. Just clown behavior. Listen to your doctors, not hacks on the internet

@DJRS2178

2 ай бұрын

what do you know?

@frontierlandfrank5314

2 ай бұрын

Statins have some exceptionally bad side effects. They should be used at the absolute last resort. This love affair with statins is gonna make a lot of people look dumb as more research comes out.

@itatae10

2 ай бұрын

​@@frontierlandfrank5314Statins have shown to kill the elderly too early as well. Cholesterol itself is no longer a risk fact and we now come up with better inflammatory biomarker to determine atherosclerosis and heart disease

@Bathrezz1

2 ай бұрын

Statins are literally proved by research to only extend your life expectancy by like 3-5day over a 5year period of use. Basically taking statins does zilch compared to improving your lifestyle.

@SaturnReturns

2 ай бұрын

Now I remembered why I was never subscribed to MPMD. His user base loves to "trust the science". Doctors are the useless hacks in my eyes.

I can understand not wanting to take statin, but some people may benefit from them depending on what their situation is. Everyone is DIFFERENT. It's a choice the patient must make if their cholesterol situation is really bad, but, who knows. We are all going to die and nothing actually matters in the sense that people think anyway, so enjoy your day.

Saladino is a crank. This does Derek no good.

@TheEthan3037

2 ай бұрын

It gets views. Derek is subtly showing the guy is a quack. 10mg of atorvastatin could be the difference in having an ascvd or not and it's virtually harmless. Sure there's rare cases a low dose could cause something but the benefit far exceeds the risk. That's what Derek is saying subtly. If he blantly calls the guy out he won't go on the podcast.

@Luke.Spirit

2 ай бұрын

Agreed completely. As someone with familial hypercholesterolemia, this Saladino guy really gets on my nerves. There are people out there really need statins to survive, and Saladino keeps saying LDL doesn’t matter

A psychiatrist giving information about Endocrine and Metabolic disorders. What a looney tune world we live in

As we Men get older this is very important to pay attention to.

Is this guy a cardiologist?

@yasseressa1696

2 ай бұрын

A psychiatrist

@humanspecieseradicationmedia

2 ай бұрын

Is your comment an appeal to authority?

Statins suck. If there were anything other than that which can modulate lipids or other functions better then it should be an option. Paul doesn't seem to think there are any other options than statins. Though I agree in ways that no pharmacology is better than none in a healthy individual to hedge any genetic bets.

good question, honed in on his bull shit.

Goofy advice.

No way 3 in a row

Ldl hld always high no matter how food is managed. All markers cancer an otherwise are good apart from lh fsh and white cells are always at the top of reference.

@Lucas_Jeffrey

2 ай бұрын

Is having lh/fsh above range even an issue? It's like getting free HCG as a gift from your own body

@Therav1

2 ай бұрын

@@Lucas_Jeffrey I heard leo steve an derek saying sometimes (rare) it can be a tumour.

No means No. 😆

Waiting for dr Idz to debunk him again

He looks sick

@jackrobinson5920

2 ай бұрын

Derek or Paul?

@jingleballs9935

2 ай бұрын

@@jackrobinson5920obviously the guy on the left lol

@jackrobinson5920

2 ай бұрын

@@jingleballs9935his cholesterol is probably high, he should take a statin 🍆 💦

@jackrobinson5920

2 ай бұрын

@@jingleballs9935 I busted to ur comment just now, sorry :(

@hansel7888

2 ай бұрын

​@@jingleballs9935so derek looks healthier you say

Huh? Why so many videos?

I don't know my ass from a hole in the ground on this subject but dude seemed purposefully oppositional no matter what was said

@TheEthan3037

2 ай бұрын

It's an act. He has to keep it up or he loses his following.

Remember that statins are as safe and effective as the last safe and effective.

Yeah, I'm not listening to a psychiatrist on this. Epic fail.

@privtprofile24

2 ай бұрын

Thanks for reminding me that he is a psychiatrist. Totally forgot.

@jacks1bonnielass

2 ай бұрын

I’m with Paul on this one tho, at least on statins. The issue is statins do far more harm than good. I’ve known many ppl who’ve been prescribed them bc they didn’t take care of themselves, so they were put on statins, then ended up with far worse issues. Prevention is EASY-diet, exercise, not smoking etc. The listed CAUSES are the accumulation of saturated fats, smoking, high blood pressure and diabetes. If you don’t take care of yourself and you look like a hippo, then eventually the doc will put you on them. They’re a drug that’s extremely overprescribed in the South.

@mosalami1548

2 ай бұрын

A psychiatrist is a doctor, and your house doc has absolutely the same education on that…unfortunately. So yes, his statements are way more qualified than those of your house doc

@privtprofile24

2 ай бұрын

​@@mosalami1548 But still wrong...

@privtprofile24

2 ай бұрын

@@jacks1bonnielass True. But paul advocates for eating a bunch of saturated fat and little to no fiber. And that is exactly what is LDL reflects.

This guy is a clown

take nattokinase

Paul’s opinion on this is dangerous for the masses. He has some good advice, but this is not it

🤨

Derek was too smart for this guy.

God he is insufferable

Look at me listenin to this pretending im smart

He should stay on his field, some people need medication even after changing their diet

Straight saprophytically f-in top tier gonadotropin stimulating conversation here bros... Very optimal. Thank you.

I really like Dr. Paul, but I have to disagree with him about this topic

What the hell does the low carb community have against statins? The side effects are so little, and benefits of avoiding sudden death so great. I believed this crap for ten years, I hope I didn't accumulate too much plaque.

@chipkipperly3904

2 ай бұрын

Idk if you have ever taken a statin but it makes you feel like absolute crap everyday. Not saying you shouldn’t take it but it definitely comes with side effects

@jeffreyjohnson7359

2 ай бұрын

@@chipkipperly3904 I've been taking atorvistatin for years. Before that simvistatin. I've never noticed any side effects. I should say that I only sporadically took the simvistatin. I was very much into low carb and later keto (I've been a type 2 diabetic since about 2004, when I was about 40). I pretty much bought the party line about LDL, saturated fats and statins. I only looked into the actual evidence a couple of years ago, and completely changed my mind.

Paul is spot on.

Saladino is too keen to have his niche. He feels like he needs to have a unique opinion on things imo

@biblical_figure

2 ай бұрын

Doctor Raymond Peat was writing about cholesterol and statins decades before you were born

@bruuhhhh

2 ай бұрын

@@biblical_figure my cardiologist has also been writing and learning about cholesterol and statins for decades before I was born. I know who I'm going to believe more.

@biblical_figure

2 ай бұрын

@@bruuhhhh your cardiologist was trained by the institutions repeating the "settled" science about cholesterol causing heart disease as established by the American Heart Association as if there's not a direct correlation between the rise of polyunsaturated fatty acids in American diets at the turn of the last century and rates of heart disease in the country keep trusting the Science™ though

@esymnysnpr

28 күн бұрын

@@bruuhhhhyou’re cardiologist is bought and paid for. And not by you.

@bruuhhhh

28 күн бұрын

@@esymnysnpr nah I'm in the UK, I have a lot of trust that my doctors are genuinely doing what's best for me

I love, and hate, when I hear things like „your blood glucose is bottom rock“ and „thyroid is good“ . Just sick statements from people who have absolutely no idea about physiology.

I love how these viral dietitians, can simply change their opinion, after they’ve told everybody to do said diet… Lol. Science and nutrition is a random educated guess, at best. The individual human body is a gigantic variable. Subscribers > Science

Im not totally against statins, but I will say that my grandfather has been on statins since they were invented. He is now 80 with end stage liver disease and he never drank alcohol.

@Lucas_Jeffrey

2 ай бұрын

He's made it beyond the average life span, and hasn't died of heart disease, pretty good.

@kurtbatman8062

2 ай бұрын

@@Lucas_Jeffrey I think it makes little sense to take a drug knowing that it will ruin your liver. "Don't have a heart attack, die of liver failure instead" because when you have 7% remaining hepatic function it does indeed look a bit silly.

@xXJeReMiAhXx99

2 ай бұрын

@@kurtbatman8062 meds are a money making scheme like everything else.

All I hear is "Bippity bloopity higgity diggity do. Flim Flam skim scam doopity doo hoo goo" I know what "Myriad" means, and that's about. Good talk though.

Saladino has a credibility level similar to Liver King.

I cant listen to a guy who still sells his carnivore book and now doesnt follow it himself.

Why take medicine when you could just stop eating animal products

@CloudCrash

2 ай бұрын

Because animal products are very nutritious and required to function as normal healthy happy humans

@_________9996

2 ай бұрын

​@@CloudCrashFeel free to spell out how they're "required"

@mikenuzzo3323

2 ай бұрын

protein ​@@_________9996

@OrionDuCros

2 ай бұрын

@CloudCrash absolutely false, I'm not even a vegan and I eat animal products myself. But I know if I ever have any heart issues I'll stop eating them because the research is pretty blatantly obvious that abstaining from meat will reduce all risk of ischemic heart disease.

@biblical_figure

2 ай бұрын

@@_________9996lmfao are you vegan

Don’t use statins please!

I have to give Derek credit for having Paul on. Peter Atia is to much of a wimp to have his outdated ideas challenged.

@Lucas_Jeffrey

2 ай бұрын

lol outdated. 8 years ago, ancient history I guess

@animalbasedguy9488

2 ай бұрын

@@Lucas_Jeffrey "The lipid hypothesis states that elevated plasma cholesterol, more specifically, LDL cholesterol, has a causal role in the development of coronary heart disease and other cardiovascular diseases. This hypothesis has been debated for over 150 years" - National Lipid Association. Great reply genius.🤣

Flat earther 🗑️

why do 75% of people who have a heart attack/stroke have normal cholesterol levels?

@Bleilock1

2 ай бұрын

They dont

@fotiskaf

2 ай бұрын

@@Bleilock1 They do, there is a research in some hospital in USA. 70% of the patients that had heart attack, had a low cholesterol.

@jlllx

2 ай бұрын

@@Bleilock1 they do

@Bleilock1

2 ай бұрын

@@fotiskaf maybe of certain kind of heart attack But not all There are different types/reasons for heart attack

@esymnysnpr

28 күн бұрын

@@Bleilock1😂 okay

Paul is so far ahead of the game. This was great to see. More and more evidence coming out that will prove him right. If you are healthy ie metabolically fit you dont need to worry about cholesterol.

@_________9996

2 ай бұрын

How do you determine metabolic fitness? What's the threshold for ignoring 'bad' lipids?

@flochfitness

2 ай бұрын

@@_________9996bingo. Everyone is an N of one. But heck, it’s your life. If you want to listen to a dude on KZread for your health advice, have at it 😂😂😂

@Lucas_Jeffrey

2 ай бұрын

what about if you're healthy and metabolically fit and a CT angiogram shows your arteries filling up with calcified plaque, even though your lipids are 'normal'? Genetics, bro. Everyone is different.

@animalbasedguy9488

2 ай бұрын

@@Lucas_Jeffrey First you would have to show what you described is possible. If you are metabolically healthy you won't get plague buildup. That's just not how it works.

@animalbasedguy9488

2 ай бұрын

@@_________9996 Like Paul said, the best metric would be checking your fasting insulin. There are other bloodwork markers you can check as well but if you follow a animal based diet without processed foods and exercise, get sunlight, good sleep, etc, you are on the right track.