Video 16 Antibody Immunoglobulin Immune Function
16) Immunoglobulin Function of the five antibodies
Let's take a closer look at the five types of antibody immunoglobulins.
IgAs are not typically found in the blood, but in secretions of the gut, saliva, sweat, milk, respiratory track, and urinary track. IgAs are part of our innate immunity and fight pathogens, such as bacteria, viruses, fungus and worms. There are two types of IgAs.
IgDs are primarily found on the surface of B-cells and account for a very tiny portion of the free floating antibodies found in plasma. And while IgDs are the least well know antibody, they are known to play a role in the activation of basophils and mast cells to attack invading microbes.
IgEs respond to allergens, such as pollen as well as parasitic worms. IgEs bind to mast cells and basophils. Once the IgE receptor comes into contact with one of these antigens the mast cells and basophils will release histamine molecules, causing the inflammatory symptoms we know as an allergic reaction.
There are four types of IgGs. IgGs target pathogenic organisms, such as bacteria, viruses and parasites. They attach to an antigen on one end while the opposite end binds with phagocytic white cells (macrophages, neutrophils, and natural killer cells) to absorb and destroy the antigen. IgGs are the primary antibody of the human body, accounting for 70-80% of the entire immunoglobulin pool. It is the smallest Ig molecule, allowing it to easily migrate into the tissues of the body. Only 45% are found in the blood. Almost every man made monoclonal antibody in clinical use is in the IgG family.
IgMs are early responders and function to eliminate pathogens early on in the attack before there are sufficient levels of IgGs. IgMs are known as a macroglobulin because of their large size. They are the largest of the immunoglobulins and make up 6-10% of the total Ig pool.
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Learned more from this explanation than hundreds of pages of my medical textbooks
I just want to thank you John Thomas. I have a premed Bio exam in three days and up until this point I was so confused but your work has really helped me out.
@stanleycheng0813
4 жыл бұрын
RICHARD WRIGHT me too
Such and effective and simple explanation, well done.
Thank you so much! These videos helped me immensely with my immunology revision!
This tutorial is SO good!! Thank you.
Simple and informative!Thanks to you❤️
Best expiation even my professor didn't explained like this.
Very nice explanation. Just one annotation 1:20 : IgG are actually just 80% of blood's! immunoglobulines, whilst IgA are the most produced immunoglobulines of the body. :)
Thank you for mentioning worms several times. This explains everything.
Very clear explaination on Ig immune system response.
Thank you for the awesome video. It makes learning the antibodies structure and function a lot easier. I totally understand them now, thanks to your good heart. I am very appreciative for the video and have subscribed to your station because you have the right voice. You seem to understand how to teach with a step by step method that works for me. Thank You Nickcole Jackson A.S. from TWU
If I could I would give you an award 🥇
Thank you sir this lecture helped me alot🤝
very short and very clear explanation that covers all the subject. thank you very much
Make more! Those videos are very informative!
thank you very much , sir, you make every thing more easier, i appreciate too mach
Short simple and pointed thanks for the CME.
Your videos are amazing and so simplified thank u so much
excellent and thorough video, thank you a ton
This was really well explained! Thank you
More about igg please?
Thank you. Really helped me a lot!
Thank you so much
Very interesting way you explain things good job and thank you
Thank you for such a helpful video
this is so helpful.. thank you sir
Great video
Love your videos!!!!!!
Thank you so much!
Great Video!
Thanks
Curious to know how long igm's are detectable in the blood after an infection, such as pneumonia.
How does "immunity" result? How rapidly do IgG and IgM antigens form? What determines HOW LONG IgG and IgM result in "vaccination," or "immunity?" I am currently working with surgeon gathering data from his office's pre-surgery testing protocols for "Covid," and the data coming out of this is truly amazing and intriguing. Thx.
Well done keep going thanks 🙏
Simple n nice 👍
I am a type two Diabetic. I had my fasting Glucose tested. My Doctor because I work in in a NON CLINICAL capacity in Hospital said I am going to order a COVID 19 anti body test. I was not really concerned about it. But I figure if he feels its important I guess I will roll with it. I had strong confidence because I did the mask thing and took extreme precautions. Being over 55 and overweight I was doomed if I got Covid 19. I felt ok. I had some breathing issues but I chalked it up to no AIR CONDITIONING in my house because the damn thing broke as the air heated up. This happened 4 weeks ago at the same time as my breathing became more difficult . 3 out of 10 scale in my opinion. Air condition was fixed and over the counter Benadryl coincided with my recovery. I started to sleep well again! TBH I did not even check my lab results until 5 days later. I was feeling great now. Again I was outside landscaping, Pulling weeds, mowing lawns, and kicking up tons of dust! When I did check my lab results I was STUNNED! My lab results as 47au igG with the Covid 19. (15 au is considered an exposure? ) I prey I did not infect anyone else. I am and was feeling better before I ever took the test! I am stunned my Hospital never picked it up. I was screened daily. Never had a temp. I did have Pink Eye? But again thank you. I spent days attempting to understand what all this meant. Yur video was spot on !!!
Awesome vdo! Thank u so much!!!
thank you Sir
supporting video , can u please discuss about structure in detail heavy n light chain
1:06 bro i think it is eosinophils not basophils, responsible for allergy..thank you about awesome video, right school must change books to such videos, it is save time..
Thank you!!
You are great 👍😃😃😃😃
Does this work with someone that’s deficient in t-cells?
0:02 They stand like celebrities lol
IgG and IgM are not specific for corona virus, just for any virus or infection 😏
good lecture
good job
Good video, tho a little too short...
شكرا لك
Hello, thank you for the video you have prepared, does low ige cause the immune system and being sick all the time, my ige value is 1.00 UI / ml ?
What are the references for all this information?
@Hoodinator17
4 жыл бұрын
Kaitlyn Matloff any textbook lol
Just to add, free antibodies are can be used to support antibody drug development.
Great 😀
Hello sir....could u please tell some herbs to selectively raise igG????
thank u
my blood test shows IgE levels at 950 and I usually feel itchy on skin, and have sticky stuff in nosal secretion. what should I do?
@AhmedGhazal1
7 жыл бұрын
You are allergic to something
Great Video! (Jesimiel Millar Fernåndez) 1M949
Ig G IS in fact the most abundant antibody in the blood.....
NICE
Respiratory TRACT not Track
I'm not good in English,i'm learning in French please put French subtitles
@drasadkhan129
8 жыл бұрын
+بنت موريتانيا .you learn english it wil be good for u
@TruthWillSF
6 жыл бұрын
بنت موريتانيا oho
my blood show Igm 1.21 I want to conceive pregnancy what should I do
my ige count is 846, am i going to die?
Sir my ige level (4201)
Hi everyone.If you read this message please read the Holy Quran the direct words and the final message from Almighty God.It will guide you to peace truth and happiness in this world and the afterworld with my lovely wishes
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