"Laughter is the second best medicine right behind medicine." I laughed so hard at that joke.

@tristanh8754

5 жыл бұрын

Bo burnham also used this joke almost exactly. I don't know that he stole it but he definitely re-used it even if it was accidental

@angelore2213

5 жыл бұрын

But the audience didn’t appreciate it as much. Shame.

@sicariusperemo3789

5 жыл бұрын

Real medicine is horrible though, a natural eating habbit instead of all the fake stuff, is the way to go. Cancer isn't a new thing, we've known that for over 5.000 years, just stay away from what's feeding it, the same crap that messes with your blood sugar, name starches of most kinds, which is the cause for all known diseases, sadly, but people think diabetes is a disease, obesity, asthma, artheritis, osteoperosis, allergies, sad to say, it ain't, it is simply about feeding your body what it needs, and not what you have available! Our ancestors didn't have any of what we are seeing today, and luckely, in most of the time, it can simply be reversed by changing lifestyle.

@storba3860

4 жыл бұрын

Healing crystals and essential oils: Am I a joke to you? Everyone: Yes.

@Enbix

4 жыл бұрын

When Seth laughs at his own joke, you know it's funny

I like Seth because he laughs at his own jokes. You have to like your own jokes first for people to laugh at them.

@angramainyu267

8 жыл бұрын

because he always try to listen to it like he's not the one telling it... he said so when voicing the people on family guy..

@gomugomu3701

7 жыл бұрын

he is drunk that's why

@TheTechCguy

6 жыл бұрын

Why would he be Peter Griffin if he never wanted to create Family Guy in the first place almost 20 years ago?

@higgsboson9509

5 жыл бұрын

That would because he's drunk, my darling. 😂😂

@CultofThings

3 жыл бұрын

My life is a joke

people who laugh at their own jokes are my favorite type of people

@donngodfather285

7 жыл бұрын

So you like idiots?

@naesamuels5131

7 жыл бұрын

a bit too much

@Blue-vd6bv

6 жыл бұрын

Donn Godfather Seth would dislike you

Most people, when drunk, think that they are the funniest person alive. Whether he’s drunk or sober, Seth MacFarlane *IS* the funniest man alive!

loooooooove seth's smile

@higgsboson9509

5 жыл бұрын

Me too. He always looks like he's up to something when he smiles 😂

@johnmurray9654

4 жыл бұрын

Gotta bring shades to look at the guy. Don't hog all the women. Cheers

Lmao he's so brutally honest and he doesn't care, and it's hilarious xD

@amandawyllis9826

7 жыл бұрын

Ikr? I could watch him all day! Lmao

I never get tired of watching this.

He so fineee😍😍😍especially when he smiles😍😍

"laughter the second best medicine right behind medicine" - Seth MacFarlane 2012

I love how honestly he's effected by the alcohol that he starts giggling st his own jokes. I'm downloading this immediately!

His laugh is so cute and contagious. Love him 💖🥰😭

ohmygod he's so adorable when he's drunk

Seth's mom died from cancer, maybe this was a way of making the topic less sad for him

His laughter is so fucking contagious!

He's so drunk 😂😂😂 His smile looks even MORE wicked!

My dream is to meet this man. I could listen to him read the dictionary and i would still laugh.

He is adorable

i love his giggle

Things I need to do before I die :Become Seth´s friend and get drunk with him...

I avoided watching this for about 20 times it was recommended but it's hilarious!

am i the only one who loves how low and sweet his voice is when he says sorry

@amandawyllis9826

7 жыл бұрын

Nope lol

@higgsboson9509

5 жыл бұрын

Definitely not lol

Jesus, he's roasting hard! LOL

"I am personally inspired by the foundation's commitment to finding cutting edge prevention and therapy for women's cancers. And I know what you're saying: "Seth, when does Ted come out on DVD?" 😂😂😂

Dude this guy is freakin awesome!

Pro-tip: Close your eyes, and imagine Brian Griffin presenting this!

He is soooo drunk!! LOL I love him!!!

He's smack dab hilarious and intelligent.. love Seth 😘

i Love how he laughs at the medicine joke!!!

seths got BALLS

Oh he's so cute 😂

Got I miss this time in society 😂😂 a smile on my face the entire vid!

i watch this every couple weeks. laugh my ass off every single time

He is the most charming person ever.

2:52 BARK BARK

Everytime I look at him, I laugh more and more.

He is hilarious and you can tell he actually cares about people he just says what everyone else thinks lol but it’s not hate. Love him so much 😂🥰

I only make jokes to amuse myself, especially if it's not appropriate. I can relate as I am also drunk.

This always puts the biggest smile on my face. Hilarious

2:50 to 3:24 i related to this on a spiritual level

You are my Idol!

His voice is like warm melted honey. I love him so much:~)

God he's so cute

love seth great roaster/comedian

its so cute he is hammered X.

EVERYTHING HE SAID IS FUNNY... I LOVE SETH

i cant stop watching

He is sooo hot

Brian Griffin ladies and gentlemen! Literally...😂😂

Beautiful

hahah ME TOOOO! i keep rewinding it

laughter is the second best medicine, right behind actual medicine XD Hilarious!!

What a tough crowd.

His jokes cut deep. Think outside the box.

funniest thing ever

if the guy wants to be drunk, let the guy be drunk. big deal

❤

So fucking awesome and hilarious

He's too fucking cute

Fucking hammered XD What a legend!

Seth..... Can we BOTH be Brian and eat Mushrooms whilst Legalising Green?? Love to do that with u some time

i need him idk

@lobsterfeet

Жыл бұрын

so me

Love how this man was just being himself, even if it meant being unprofessional, he's so fucked up lmao

he wasn't drunk, he started off good but noticed the audience were either too drunk or too stupid to get his jokes so he had to laugh after each one to signal them that it was in fact a joke to laugh at or just a joke in general

(at least he was laughing at his OWN "jokes")

God he's so funny

lol he so stoned, he is the best!

yeah, me too :-)

Lmao!

Close your eyes and its just Brian 😂

Am I the only one who notices the piece of hair on his chest that doesn't belong to him.

@cathrineleren9665

9 жыл бұрын

Nope. Annoying as fuck. #ocd But I don't believe it's hair, it's more likely a loose thread from his shirt's stitching.

@goondocksaints9597

9 жыл бұрын

Kefah Jaber It's actually a part of a huuge Justin Timberlake tattoo on his chest.

@TheBrandiElizabeth

7 жыл бұрын

I think it's actually a thread from his shirt! It's that same maroon color if you look closely and when his collar shifts, it does too. I spent a good few minutes staring trying to figure it out too.

@shouldileavesatanforraphae2395

5 жыл бұрын

Kefah Jaber he has a muscular chest ....so amazing

@sheilaschumacher3946

5 жыл бұрын

No, I saw that. It drove me crazy!

I bet he makes Family Guy impressions in bed.

@kayleightheshamelessbitch6995

4 жыл бұрын

I know your comment is 6 years old, but I would love if he did!!!

I love Seth.....I can't wait for Sunday, the first time I will watch the Oscar

I think he was drunk ..bt i like that speech

This aged well

Someone was high...

this makes me think of the comedy awards south park episode, funnybot

Drunk seth

Come on Seth, drink AFTER the speech!

@tsfbaf303

7 жыл бұрын

LoydMongo why

@alliecardinal1768

5 жыл бұрын

Idc he’s kinda adorable

Jokes ages like wine. Just like Norm Macdonald he laughs at his own jokes which are curated for him. His mother had cancer, to be this uncaring about something so close it is refreshing to see someone be funny without caring.

oh man that was brutal....

@amandawyllis9826

7 жыл бұрын

Ikr? I love it when he doesn't hold back LOL

The reason he was like that beacase he was drunk.as fuck and it was really late. He probably was tipsy and you know that time at night where everything is funny. I'm guessing it was that time of night. I love him though

Charlie Sheen: "It's like he is jealous of his own creation"

@julicoole

4 жыл бұрын

That was patrice O'Neal

Brian Griffin giving a speech

the first best medicine is well... I'll leave it to you to decide

He's laughing because he's loaded up on beer, Weed, and annoyance lol

awww I really liked them as a couple :(

yeah I wanna see Bill Maher !

Is his joke at 2:58 an homage to Bo Burnham?

@tristanh8754

5 жыл бұрын

Actually I believe seth said it first. Not that Bo stole it but I think they just both made very similar jokes lol

hello Ted...

me too . it would be a night/s or even days not to forget . A girl can dream........

Well, I don't know about that. I'm a fan of both of them.. and I'm not denying anything, only stating what Seth wrote on his Twitter. They look cute together though. ;-)

He could be superman

He's so adorable I want to hug him when he's drunk....don't ask I have weird stuff I like I just realized that Woodbury is very fitting since he's cute when drunk

He's not drunk, he's stoned.

@rhinohorn1258

8 жыл бұрын

Wrong he's Seth macfarlane get it fucking right

@palefox

8 жыл бұрын

I think he's both

@angramainyu267

8 жыл бұрын

he is actually both,,, drunken high....

@ambergriff135

8 жыл бұрын

+Angra Mainyu Lol he's gotta be both, seen him drunk and he doesn't laugh so much haha he's definitely stoned

Hey he sounds like brian griffin

the audience doesn't laugh enough

Remember Adam West

@Mor Abed

Does anyone sees the blue clove😂😂😂😂

I wish he buttoned up one more