very good video, thank you n keep up the good work.

It was really clear thank you! However, I still have one doubt: how did you complete the rest of the matrix at the beginning? For example, you said that since S and S are a match, no penalty would be added, therefore you wrote 0. When it is a mismatch we should add one penalty. But in U x A you wrote 1 and there was already one penalty, shouldn't you've written 2? I hope my question is clear enough! (3:33)

@BioinformaticaYT

3 жыл бұрын

Yeah i got your question. Here we can add the penalty by three ways, first is to add it horizontally ( here for adding horizontally one would add 1+1 that becomes 2), Second way is to add vertically ( it would be also 2) And the third way is to add it diagonally ( in this case diagonal number was 0 and if we add 1, it becomes 1) Now we should select the way in which minimum number is the resultant, hence we have written 1 for u * a.! @julieta Lanter I hope your doubt is clear 😊

@julietalanter9249

3 жыл бұрын

Thanks for answering!! I understood it :)

Nice 👍 video

❤️❤️❤️❤️

It was so helpful. Thank you. But where did the -11 came from? How do we assign gap penalty numbers?

@BioinformaticaYT

3 жыл бұрын

Here we have assumed it to be - 11, the thing one needs to keep in mind is that gap initiation penalty must be higher than gap extension penalty..! And the number of gap penalty varies according to the algorithms used.! Happy to help 😊

@glycine5620

2 жыл бұрын

@@BioinformaticaYT For example?