The sciatic nerve is a major nerve of the lower limb. It is a thick flat band, approximately 2cm wide - the largest nerve in the body.
The sciatic nerve is derived from the lumbosacral plexus. After its formation, it leaves the pelvis and enters the gluteal region via greater sciatic foramen. It emerges inferiorly to the piriformis muscle and descends in an inferolateral direction.
The compression of the nerve can cause sharp pain throughout its course.
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