RNAi: Slicing, dicing and serving your cells - Alex Dainis
View full lesson: ed.ted.com/lessons/rnai-slicin...
RNA, the genetic messenger, makes sure the DNA recipe gives your cells exactly what they ordered. But sometimes that means inhibiting some other RNA that got the recipe wrong. This process is called RNA interference (RNAi), and it acts as a self-correcting system within the complicated genetic kitchen of your body. Alex Dainis explains the importance -- and exciting potential -- of RNAi.
Lesson by Alex Dainis, animation by Cinematic Sweden.
Пікірлер: 184
The quality of the animation is sooo good! I'm used to seeing amateurish work in these edutainment animations. This animator actually understands stretch, correct physics, motion blur etc.
@KnakuanaRka
5 жыл бұрын
secondjoint Great animations, but I do think that the metaphor shown by those animations only manages to confuse the matter instead of clarifying.
@toobaaaapi
5 ай бұрын
Quality of animation is good but the content was not upto mark, ended confusing the topic more than clarifying it.
I couldn't understand RNAi well, but this lecture is very clever and help my study so much! Thanks!!! Before then, I was a little confused by technical terms of this phenomenon.
This is the best explanation out there. Thanks a bunch! Really appreciate it.
I wish to contribute myself in creating this kind of educative videos when I grow up. This is so much meaningful.
@justagreekinternetuser8998
Жыл бұрын
so, did you?
Great video , best metaphor ever and I like the cute animation
Congratulations Alex! What an accomplishment...
Amazing communication of science in this video!
This video is absolutely amazing
Moral of the story, Chop up unsatisfied customers.
wow Alex! That is way cool. You are certainly making an impact! Thank you!
Loved it .....well done Alex
Thank you for the lesson.
woww........difficult topic explained in very easy way.......thanks a lotttt
Best TED video, ever!
this video is so amazing.
The voice has perfect timing to understanding.
This video is awesome! Its so informative! Good job alex!
wonderfully done
Best video on this topic...Thanks a lot😊
A fantastic video, thank you for this
OMG what a great explanation!
Nice animation! I liked it a lot
The animation was awesome
The cooking metaphor sorta makes it a bit more confusing for me
thank you for making wonderful video
Let me summarize everything in one shot ( actually this is the project that I've been assigned) So rna interference is basically used to prevent gene expression ( prevention of translation and hence production of proteins ) So to do it artificially we use vectors and introduce the desired dna . Now this dna produces both sense and anti sense strand these being complementary to each other bind together . Dicer proteins sense these and chop them and these thereby approach the m rna and slicer protein comes and chops down the m rna too So , viola ! We've successfully prevented the gene expression
@Sapnakolira
2 жыл бұрын
So in eukaryotes these double stranded rnas are created in response to an attack by viruses???
@lemonade4865
2 жыл бұрын
Wait aren't you supposed to use desired Double Stranded RNA and not DNA for the vector?
@justagreekinternetuser8998
Жыл бұрын
@@Sapnakolira no. Sometimes, viruses have genetic material in the form of double stranded RNA, instead of DNA that we have. So, they insert it in cells and manipulate their cell functions, in order to replicate their dsRNA and move to close cells and infect them too.
Perfect explanation
Lovely video. Thank you.
That RNA decking the other RNA caught me off guard and had me bustin up!
Congratulations alex, this is cool!
Succinctly narrated; wonderfully illustrated :)
What a classic video. I watched this video when I was studying for my MCAT and now I am in medical school, studying for USMLE Step 1 and came across an RNA question and it reminded me of this. Thank you so much for these videos!
what was that at 2:18, wooallaaaa....!! 🤣🤣🤣🤣🤣🤣🤣. Nice animation and correctly explained with an example of a kitchen. Pretty helpful for explaining to the students. 👍 👍 👍
That video was great really love it 😍😍
Congrats Alex!
Thanks I'm good at learning this way
Aw well done Alex!
such a nice video.
Oh man that was impressive I understand everything. ❤thank you
That is stunning 😍 Thanks a lot 🙏 💓
AHHH this is so addictive.
superb video !
Alex for the win!
beautiful. thanks
very nice and simple
This is so cool and easy to remember now XD thanks
thank was sooooo amazing people
too good difficult concept discussed very easily
@farhanahmed2508
7 жыл бұрын
kirtika Saxena Good evening, Ma'am...
@Andy-km1xp
6 жыл бұрын
Farhan Ahmed lol Creepy
what a cute animation!
Where were you when I was looking all over KZread to understand rnai for my biology test yesterday 😭😭😭😭😭😭😭😭😭😭😭
this video is 4 weeks to late. tried to understand it for an exam, but the information given was too confusing. this video sums it up perfectly :)
Wow! So complex yet so organized and it all happened by chance?...At least that's what some people believe. This is what science must be all about. Things we can observe, study and test.
well explained
Thank you
superb..........saw genetic engineering class via kitchen mechanism
Trying to make it relatable, you guys screwed with the explanation 100 times more!
Wow I didn't know Alex Dainis narrated a Ted-Ed video !
cool video!
Why good videos like this has so little watches?
THANKS!!!
I read that RNAi is also being used to deal with the varroa destructor mites that are devastating beehives.
perfect!
Ribosome: what can I get for you Red blood cell: S-Sugar Ribosome: so glucose? Red blood cell: S-S-Sugar Ribosome: I don’t have the full ingredients for that Red blood cell: rolls on the floor screaming
I'm shocked when I saw that this video is 10 years old! I'm currently working as a research physician with a pharma company developing RNAi drug to treat obesity.
wow! amazing video
@user-hx5rc7zv7m
8 жыл бұрын
узбеккино
@user-hx5rc7zv7m
8 жыл бұрын
узбеки но х узбеккино
there are many kinds of rna, some sends message from dna to the ribosome to create proteins, some are attached to the ribosome used to create protein.
perfect
Yay Alex! :)
Very good:)
Thx
Was just about to skip this on my sub list. Then I saw the name Alex Dainis. :-)
Alexxxxx!
😄 great job.
what's the difference of rna and dna?
Something along those lines, but NO, no one volunteers. Neuroscientists study patients who already had an accident or a stroke, which lead to damage in certain localities in the brain. During and after preliminary treatment by ER physicians and/or neurosurgeons, scans are done, including MRI, fMRI, CT, PET, etc. which help localize the injured parts. After doing whatever they can, the patients are assessed behaviorally and compared to before the accident, etc., as well as normal brain scans.
Plz explain this topic liteally
nice
Hello TEDed. I love your videos. All your videos very interesting but in some case I try to understand without transcript as I'm not native speaker. Can I have this transcript from somewhere. Thanks.
wow just wow
@marioguts
8 жыл бұрын
+taeyang Same!!! I think people in general need a little bit more of previous knowledge to fully understand the video but it amazing nonetheless
How do you manipulate expression in gene expression, is this possible to do within yourself without any external help?
@lachlanmc2335
Жыл бұрын
yes like if u starve yourself the genes will express differently in response to lower levels of some proteins in blood to metabolize slower
Muy buen video, hacen verlo muy muy fácil , pero no lo es jeje :)
imagine ur body housing silent assassins. lol
This was awesomely violent.
The body is [mostly, I think] reactive not active. Enough material is floating around inside to keep the process going even though the prices don't know where they're going.
How does our cells know which RNA is virus RNA vs our own good RNA
The animation is hilariously violent!
the animation is so cute
I like how she said volia
You could have made the pieces of the double stranded RNA look alive like smaller living parts of it :P
Wow, gruesome.
@siyacer
4 жыл бұрын
Drusome
I'm a bit depressed that the video isn't in german. It would be pretty perfect for my presentation tomorrow, but in fact its in english - most of my course wouldn't understand it directly :(
@tygonmaster
8 жыл бұрын
+Ladiduify There are German subtitles. :)
slice and dice
Life is... mindboggingly complex and amazing, Also cute, as it seems.
중간에 나오는 푸른빛집명나방이 아니라 예쁜꼬마선충(C.elegans)이 맞는거 같은데 ... I think that Korean subtitles are wrong. lI hear as [예쁜꼬마선충 - C.elegans] , but the Koean subtitle is [푸른빛집명나방Teliphasa elegans ] 영어 고수님들 이거 보시면 제대로된 영문으로 작성좀 해주세요.....ㅋㅋㅋㅋㅋㅋ
Turkce altyazi icin tesekkurler
Clearly many things chemicals could never do without being directed by a Maker.
the RNA part was always the most complicated in genetics
i am still confused...
that brutally escalated quick.
I'm sure I'd understand it better without the metaphor lol
@alineangel3210
6 жыл бұрын
dingovory I'm almost sure that you wouldn't. I've tried to understand this for half a hour by biology videos, this video gets the information a lot easier... ;-)
@LegeFles
6 жыл бұрын
Aline Oliveira yeah no