Promoter and Termination Sites of Transcription

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  • @ftothel794
    @ftothel7948 жыл бұрын

    A genius is not someone who does very complicated things. A genius is someone who does very complicated things and make them look very simple.

  • @hibahaitem7878

    @hibahaitem7878

    2 жыл бұрын

    I agree one hundred percent

  • @beaudiakow9394
    @beaudiakow93945 жыл бұрын

    I love how every single lecture he ends with the same face. I know he's just thinking "I slayed that damn lecture"

  • @inspiredbylindaoforiatta7699
    @inspiredbylindaoforiatta76998 жыл бұрын

    when I go for lectures I just write down the topic and come and search for it from your videos. ..I mean u are the best teacher ever

  • @Arosya
    @Arosya8 жыл бұрын

    I have passed my biochemistry exams thanks to your videos. It would be fantastic to have you cloned and placed in to our lecture halls :) Thank you for all your effort!

  • @AKLECTURES

    @AKLECTURES

    8 жыл бұрын

    +Arosya haha! thanks for the kind words, great job on your recent exam!

  • @hibahaitem7878

    @hibahaitem7878

    2 жыл бұрын

    @@AKLECTURES you're the best, thank you so much for all your videos

  • @dhiaawad6710
    @dhiaawad67104 жыл бұрын

    AH man, I was so stressed about the lecture before I watch your video. what my prof. try to explain in 50 minutes you did just in 10 minutes. very very thankful.

  • @MatirManush-wu9cc
    @MatirManush-wu9cc6 жыл бұрын

    "AK LECTURES" are wonderful videos. These lectures are continuously helping us to understand the most complex processes of Biology and Biochemistry. We really appreciate this great professor of Biology/Biochemistry. And we are really grateful to him.

  • @rantaytay
    @rantaytay5 жыл бұрын

    Thank you so much, the notes I take during these videos are a thousand times more helpful than the ones I take in class

  • @bidezhang4767
    @bidezhang47678 жыл бұрын

    I just find all your videos so useful and your explanations are so clear.Hat off to you, sir. Thank you for doing all of these videos

  • @flexogore4614
    @flexogore46146 жыл бұрын

    Your short videos are much more useful than the most of my university lectures!

  • @usmanahmed3173
    @usmanahmed31737 жыл бұрын

    thank you 😊 tomorrow is my test and I was running out of time to prepare it but you explained the topic so well that I am quite confident for tomorrow:)

  • @joshuapontier6956
    @joshuapontier69568 жыл бұрын

    You are very articulate...Thank you for creating videos which clarify complex ideas. You're amazing.

  • @davidi686
    @davidi686 Жыл бұрын

    I graduated from university 7 YEARS ago and you channel got me through ❤

  • @taiyabshaikh9885
    @taiyabshaikh98854 жыл бұрын

    splendid, even point out the minor details. i dont know how much grateful i m to your lectures. keeeeeeeeep up the good work. god bless you

  • @Dianax.
    @Dianax.2 жыл бұрын

    Helped me while I was an undergrad and helps me now that I'm a grad looking back at the basics to understand more complex processes :')

  • @nouralshihaby7476
    @nouralshihaby74765 жыл бұрын

    From syrian Arab Republic thank you man 💙💙💙

  • @williamcooper5152
    @williamcooper51526 жыл бұрын

    very well explained video, even for forein people! It will make me pass my biochemistry exam in one week :) Greetings from Germany!

  • @juliadomingues1999
    @juliadomingues19993 жыл бұрын

    Dicção perfeita!!!!!! Amei o vídeo e a explicação

  • @redorr6008
    @redorr60089 жыл бұрын

    Hat off to you sir. I bet many people will find in these videos the enthusiasm and skill to teach that many times is kacking in their classrooms. Brilliant performance, :)

  • @AKLECTURES

    @AKLECTURES

    9 жыл бұрын

    Red Orr thank you for the kind words! :)

  • @dananguyen2388
    @dananguyen23884 жыл бұрын

    thank you so much for posting these videos. super helpful and you make subjects easier to tackle. Super appreciative!!

  • @iraqi3612
    @iraqi36122 жыл бұрын

    I can't stop thanking you thank you doctor

  • @KemeticGoddes
    @KemeticGoddes7 жыл бұрын

    You are a excellent teacher! Wish you could come and teach at my university. Thank you so much for your videos!

  • @denissemorales9947
    @denissemorales99475 жыл бұрын

    I love you, you make things look so much easier hahaha

  • @hh-zq9io
    @hh-zq9io8 жыл бұрын

    thank you for sharing, Really very helpful, cant thank you enough.... u r talented

  • @phelokazingqamakwe1109
    @phelokazingqamakwe11097 жыл бұрын

    Thank you, Sir, I am your biggest fan. Excellent work.

  • @dblakecampbell
    @dblakecampbell9 жыл бұрын

    You have a special gift.Thank you for sharing!

  • @AKLECTURES

    @AKLECTURES

    9 жыл бұрын

    Dayna B Thank you for your kind words Danya!

  • @baharehniati2706
    @baharehniati27067 жыл бұрын

    you're a genius! Thank you!

  • @ayummuchan2374
    @ayummuchan23747 жыл бұрын

    Your my superhero in the medschool

  • @purpleheartpurpleheart4373
    @purpleheartpurpleheart43733 жыл бұрын

    excellent clarity! you are well understood

  • @adammohammed8673
    @adammohammed86735 жыл бұрын

    excellent explanation. you have made it simple to understand

  • @carlosyanes4446
    @carlosyanes44464 жыл бұрын

    I thank you so much every single day!

  • @sepidehtavakoli1097
    @sepidehtavakoli10975 жыл бұрын

    Great lectures ever!

  • @munasaoudi7846
    @munasaoudi78468 жыл бұрын

    how beautiful your explanation is !

  • @juwelen6168
    @juwelen61687 жыл бұрын

    wooow !! thanx for the amazing explanation

  • @hma141
    @hma1419 жыл бұрын

    I think I'll pay a lot for such teaching in my country, thank you

  • @brandonmansfield6918
    @brandonmansfield6918 Жыл бұрын

    The BEST TEACHER

  • @khalidhanna1106
    @khalidhanna11067 жыл бұрын

    Thank you for the efforts

  • @iraqi3612
    @iraqi36122 жыл бұрын

    Thank you very much doctor

  • @maryamelbarbary7427
    @maryamelbarbary74278 жыл бұрын

    your very helpful thanks your great keep it going

  • @afradarvyshi4300
    @afradarvyshi43003 жыл бұрын

    Very useful, thanks a lot🙏

  • @matthiasturcar7329
    @matthiasturcar73293 жыл бұрын

    Great Video, keep it up

  • @sarahnicolas3301
    @sarahnicolas33017 жыл бұрын

    Why can't you be my professor! You explain everything so well, I actually understand it!

  • @asiakhatoon954
    @asiakhatoon9543 жыл бұрын

    Legend 😍😍😍😇😇😇thanks a ton

  • @JN.S.M
    @JN.S.M2 жыл бұрын

    You are my hero.

  • @inesgonzalez2246
    @inesgonzalez22462 жыл бұрын

    Awesome lecture 👌

  • @suv2599
    @suv25994 жыл бұрын

    Amazing lectures

  • @chooyuanchun4836
    @chooyuanchun48366 жыл бұрын

    +AK LECTURES I think you should distribute this video into two, one for prokaryotes while another for eukaryotes. Thank you very much for your lecture! I really appreciated it! #bigfanfromyou

  • @asgharshah1986
    @asgharshah19863 жыл бұрын

    You are Fantastic

  • @nehaverma1440
    @nehaverma14409 жыл бұрын

    Awesome expalanatin..thank you sir..

  • @AKLECTURES

    @AKLECTURES

    9 жыл бұрын

    neha verma you're welcome :)

  • @sanemsariyar4039
    @sanemsariyar40398 жыл бұрын

    It is written DNA template, isn't it nontemplate stand? Actually 3' to 5' one is template I guess.

  • @fishingthesound7923
    @fishingthesound79233 жыл бұрын

    감사합니다

  • @coldarkworld7412
    @coldarkworld74125 жыл бұрын

    sir you are the best

  • @Chrysolite-kn3mz
    @Chrysolite-kn3mz3 жыл бұрын

    thank you soo much!!

  • @balu16col
    @balu16col7 жыл бұрын

    CAAT box sequence is wrongly mentioned as GGNCAATCT,rather than GGCCAATCT !

  • @DaFan86
    @DaFan867 жыл бұрын

    You are a saint

  • @DAKSPALM
    @DAKSPALM4 жыл бұрын

    Genius!

  • @vikrantgoswami4987
    @vikrantgoswami49874 жыл бұрын

    Sir i follow Biochemistry Book by Donald Voet and Judith Voet . I found lot many details in this book do you have videous that talks about these details ... I found your videous very helpfull .. Thanks for nice lectures.. :)

  • @GeneticsLessons
    @GeneticsLessons7 жыл бұрын

    3:30 There is a mistake in the video on the picture there is not a DNA template strand but CODING strand because mRNA is made in 5'-3' end direction and all the names on the DNA strand are given as are on codding strand of DNA not template.

  • @JongensJavaanse

    @JongensJavaanse

    6 жыл бұрын

    It is written wrong but he is explaining it correctly

  • @issackabdi6946

    @issackabdi6946

    5 жыл бұрын

    Sure

  • @issackabdi6946

    @issackabdi6946

    5 жыл бұрын

    J

  • @aleksandrtukallo2291
    @aleksandrtukallo22918 жыл бұрын

    Really cool video! But I'd like to mention, that when you describe CAAT box for eucariotic cells, it is written on the board, that it is GGNCAATCT, which can not be true, because there is no nucliotide N. According to wikipedia, it starts as GGCCAATCT (N is changed to C).

  • @SixTough

    @SixTough

    4 жыл бұрын

    N stands for anything

  • @Procrastinerd
    @Procrastinerd9 жыл бұрын

    Do most eukaryotic transcriptions tend to separate via termination by a stem-loop signaling, or is more thanks to the function of RNA helicase?

  • @ritairurhe6981
    @ritairurhe6981 Жыл бұрын

    Hi thank you for all your videos. Do you have more please especially on biochemistry

  • @AKLECTURES

    @AKLECTURES

    Жыл бұрын

    check out the website in the description.

  • @tyfooods
    @tyfooods8 жыл бұрын

    Says DNA template, however isn't the DNA template strand the complement of RNA transcript? It should be the coding strand, because it is not the strand that is read.

  • @zauberdiva17
    @zauberdiva173 жыл бұрын

    Super,thanks! A stupid question but how does enhancer sequence just bind to the site as a promoter? Does the DNA just bind to itself? How does it get there?

  • @stevesibo6036
    @stevesibo6036 Жыл бұрын

    On the whiteboard is a diagram of 5’ to 3’ DNA with the pribnow promoter box shown to the right of the 5’ end of a DNA single strand. Yet you say it is the compliment of this strand that is read by the RNA polymerase starting at the 3’ end of the not shown “template” strand. If so, then what is the nucleotide sequence for our pribnow promoter site? Shouldn’t the nucleotide sequence of pribnow be the compliment of the shown TATAAT? Which is really ATATTA? Can you see the dilemma here?

  • @dinarazat2255
    @dinarazat2255 Жыл бұрын

    bless you

  • @MohamedEmad-yh7ig
    @MohamedEmad-yh7ig9 жыл бұрын

    pefect.....thank you :)

  • @AKLECTURES

    @AKLECTURES

    9 жыл бұрын

    Mohamed Emad You're welcome!

  • @PrayEveryDay
    @PrayEveryDay6 жыл бұрын

    Great video! Thanks! Quick question. Is 35 and 25 distance from transcription in prokaryotes and 1000, 75 and 25 in eukaryotes hard distances, are they an exact average, or are they rough approximations?

  • @chooyuanchun4836

    @chooyuanchun4836

    6 жыл бұрын

    They are only rough approximations because it might differs from different individual not every individual having the same amount of nucleotides in a certain strand of DNA hence when it was being transcript then the amount differs too. For approximations of -35 and -10 nucleotides upstream sequence are for prokaryotes while in eukaryotes are -25 to -35 nucleotides upstream sequence ( these are all just rough approximations ) nobody can give you the exact place for every individual as I mentioned it differs. :)

  • @sanjuvegad9290
    @sanjuvegad9290 Жыл бұрын

    Question Tata box sequence is located on template strand or coding strand ???

  • @ritachiaha8187
    @ritachiaha81873 жыл бұрын

    Pls sir, the strand the promoter regions are on, is it on the 5' to 3' or on the 3' to 5' . Thanks so much

  • @michaels3144
    @michaels31447 жыл бұрын

    I was watching your video on eukaryotic gene structure and there you said the RNA Pol II binds to the transcription start site. Now in this video you said it binds to the promoter. im confused....

  • @manuellopezsheriff5033
    @manuellopezsheriff50332 жыл бұрын

    this video is not inside one of your playlists, is it? If it is, I want to see that playlist!

  • @_aryacore
    @_aryacore3 жыл бұрын

    He literally prints a whole guide on his white board.

  • @sicilianotoronto
    @sicilianotoronto4 жыл бұрын

    which lecture involves the rho?

  • @jamthemanster
    @jamthemanster3 жыл бұрын

    Well that’s it, this is how I pass Cell Biology.

  • @jamesfilosa6277
    @jamesfilosa62778 жыл бұрын

    *looks at top right corner of whiteboard* - Are all eukaryotic genes called Eugene? hehe. Thank you once again!

  • @jonathanweiss6741
    @jonathanweiss67418 жыл бұрын

    do you have an RNA transcription for eukaryotes??

  • @misbahashraf9485

    @misbahashraf9485

    8 жыл бұрын

    +Jonathan Weiss i guess so yes.. and its promoter sequence ranges from -25 and -75. and its somewhat obvious if there wont be any transcription process then how ur body would be able to produce proteins, as we know that RNA helps in protein synthesis. I hope m clear to you.

  • @arunjohn4525
    @arunjohn45256 жыл бұрын

    Can i just know ,what does N stands in CAAT box please.

  • @wafasaliha1552
    @wafasaliha15527 жыл бұрын

    am so confused where is the promoter located is it on the sense dna or what plz answer me

  • @aguardsjohnson8942
    @aguardsjohnson89426 жыл бұрын

    You are incredibly a nice teacher, kindly improve on your conclusive remarks.

  • @dimplemevliwal4137
    @dimplemevliwal41376 жыл бұрын

    Sir can you please give lecture about translation

  • @tahirtantary7438
    @tahirtantary74384 жыл бұрын

    why transcription factors are in eukaryotic transcription but not in prokaryotes?

  • @nomsahabeenzu8219

    @nomsahabeenzu8219

    4 жыл бұрын

    Woooooooooow awesome 👌 💕 👌 well explained, thanks so much

  • @misbahashraf9485
    @misbahashraf94858 жыл бұрын

    hello sir, actually i didn't get what do u mean by bacterial gene>? i mean i know what is gene but how transcription can start from -10 units or -35 units from bacterial gene? i just didn't get that point. :D @aklectures thanks for delivering worthy lectures!

  • @jamesfilosa6277

    @jamesfilosa6277

    8 жыл бұрын

    +Misbah Ashraf - I think the answer here is that RNA polymerase spans a large region of DNA before the gene. The core enzyme has a mass of hundreds of kDa... So the complex is large enough, and has enough active sites, to recognise promoter sites. Transcription does not start at these sites. Transcription starts at 0. -10 and -35 are in relation to transcription start.

  • @Iyami001

    @Iyami001

    8 жыл бұрын

    +Misbah Ashraf The promoter region is just where RNA Polymerase will bind to the template. It does not actually start the transcription process until it gets to the start codon nearby it.

  • @MrOkimhere
    @MrOkimhere4 жыл бұрын

    Why do has the mRNA of prokaryotes no promoter?

  • @Procrastinerd
    @Procrastinerd9 жыл бұрын

    What does the N denote in the CAAT box

  • @holohedx2

    @holohedx2

    8 жыл бұрын

    +Cognitive Philosophy Don't quote me on this, but I think it just means nucleotide, as in any base can go there.

  • @MagicTurdd

    @MagicTurdd

    8 жыл бұрын

    +holohedx2 yes it does

  • @kaylachapman7178
    @kaylachapman71788 жыл бұрын

    why can't you be my biochem professor :(

  • @shakedlw3394
    @shakedlw33946 жыл бұрын

    LOL we look alike, a little bit. only 99.99999999% identical.

  • @md.torikulislam9444
    @md.torikulislam94445 жыл бұрын

    boss