NOTE: Low bandwidth video compression struggles with large numbers of randomly-moving particles such as confetti or the diffusing ions and molecules shown in this video. If the video looks muddy or you can't see what's happening, you may need to switch to watching the HD version of the video: click the gear icon next to the video then 'quality' and select the 1080p or HD version. Also, watching on a computer with a large screen and good internet connection will help. The most affected parts are from 4:00-4:30 and 5:12-6:00 in this video. My apologies for the compression artifacts, but fortunately KZread allows you to select higher quality versions if your device and internet connection allow.

@simonpeggboard4004

2 жыл бұрын

How are the different frequencies or colours of light translated to the nerve cells? As it appears that only a black and white image would be produced from this set-up. Great video series by the way, keep making them and the views will come.

@borgholable

2 жыл бұрын

just discovered your channel , i hope you keep going man this is truly mind blowing

@koharaisevo3666

2 жыл бұрын

@@simonpeggboard4004 This video demonstrate the working of a rod cell, indeed it produce black and white image. To detect color we need signal from 3 different kind of cone cell each sensitive to a range of frequency.

@theweld4081

2 жыл бұрын

I think if you were to do more animations like these in the future, simplification when dealing with areas affected by compression may be a good idea. Things like showing the rhodopsin, transducin, and phosphodiesterase as simple spheres might make the whole thing a bit less artifacted! Nevertheless, thank you, this video was great!

@JBulsa

2 жыл бұрын

How can this biology be used to sequence electrical charge for OGM, Saphyr $BNGO $27 Call options for 22 Jan. currently $5.42

As someone who did a whole degree in molecular biology, I can't stress enough how well-made this video is, specifically in relation to the "quantitative thinking" concept and visualising/explaining the real physical interactions that take place, instead of just explaining a singular, neat cascade like most university lectures do. The "random motion" part of such processes is almost never elucidated and students come away thinking things are a lot more static and straight-forward than they are. Translation is a classic example, where the mechanism is described something like, "the ribosome incorporates the next amino acid in the chain," rather than letting students know that the correct amino acid actually has to randomly bump into the complex for that to happen - it sounds counter-intuitive unless you have a good grasp on how fast molecules are bumping around and interacting per second.

@kennethbransford820

Жыл бұрын

=== How is this by accident Mr. Pinata Oblongata? ==== Evolution = Self Assembling Atoms = Impossible ======

@PinataOblongata

Жыл бұрын

@@kennethbransford820 Hi Ken. First, let's take a look at the motivation for your question: You are likely a theist of some description who has decided to believe, at face value and without evidence, in some god myth or other, most likely of Judeo-Christian origin. Now, believing something with no evidence and then finding that evidenced reality conflicts with those beliefs is not a good reason to criticise the evidenced reality. It's also not logically sound to go about denying or trying to argue with evidence reality because you don't like it or wish it was different. The proper way to investigate and understand the world is simply to form hypotheses based on observations and then test them - that is the scientific method. Nothing you could ever observe would ever require you to hypothesise wildly about the existence of a god, and cultural god concepts are not testable hypotheses. Secondly, atoms are "self-assembling" all the time. Oxygen atoms in the air come in the form of O2 - two oxygen atoms "self-assembled" together. Basic chemistry tells us that their arrangement of electron orbitals are such that they tend to form covalent double bonds when coming into contact, much like two magnets with opposite polarity will attract. Hydrogen likes to bod with itself and another oxygen atom, you may have heard of the compound that produces, we call it "water". Now, what I think you meant was that amino acids supposedly can't self-assemble into proteins or that nucleotides can't self-assemble into nucleic acids, but you're out of luck, because both of those things happen all the time, too. In living organisms, however, mechanisms have evolved over time to make these processes more efficient so that the genes of the organism will be protected and replicated by the organisms surviving to reproduce, perhaps many times over. This is because the very first self-assembly of proteins or nucleic acids that were more successful than others were those that were shaped in such a way that they made copies of themselves - and all life since has just been ever more complex ways of continuing to do that. We know this happened because we can use genetics to trace the evolutionary relationships of different organisms and see where they are genetically the same and where they differ. All living organisms have 1 or more HOX genes that control the developmental layout of the organism. They are very old genes that we all share, going right back to simple sponges. We also see mountains of other evidence for evolution from numerous fields all adding up to so much that now we call it a theory, meaning an over-arching and undisputable framework for how reality works, akin to a law in mathematics. So even though it's impossible to have fossil evidence of the very first self-replicating molecules, we know they had to exist. If you think assuming gods and creation myths is somehow more reasonable than simply following the empirical evidence to see what it tells us, you're just wrong, like you are probably wrong about most of what you think you know, because you've been indoctrinated with bad ideas with no supporting evidence and haven't spent enough time trying to understand sound ideas with tons of supporting evidence. You probably don't even understand the requirement for evidence or what constitutes acceptable evidence.

@kennethbransford820

Жыл бұрын

@@PinataOblongata === Thank you Mr. Pinata Oblongata for replying to me. I hope you don't mind as I will answer you using both of your comments here on this You Tube thread. The vibrating of atoms firstly is astoundingly fast as I have just found out. 8 THz = 8 000 000 000 000 vibrations per second. This takes me aback very badly. I had no idea. Also you failed to mention not all atoms can self assemble and create living systems or life. This is so much more complicated then methane or water forming since these are based on the natural energy levels based on the laws of physics. What laws are involved for the existence of your organic computer brain? The abilities that you are now in possession of allowing you to think, and to have consciousness, using complex formulaic chemical equations that so-called happened from dirt is? IMPOSSIBLE. The folding protein molecule is just one example that design did it. This universe didn't just happen with all of the laws of physics and chemistry originated from. You also have our planet earth that once was a ball of rock floating through space. How did the correct ratios of gasses and atmospheric pressures happen? Our oceans were at on time toxic. Photosynthesis didn't exist. How did the chlorophyll molecule come into existence? Like that brain of yours. How did an organic solar panel able to split atoms using energy from the sun happen by so-called accident? How did the fine tuning of the universe happen, where if the electromagnetic forces for bonding were a trillionth stronger or weaker, we wouldn't be here. If the laws of quantum mechanics responsible for quantum tunneling didn't exist, our sun would stop shining. There are so many combinatorial numbers and mathematics needed for your existence that DESIGN, is the only ANSWER for your existence. You just don't know any better in that you were not by an accident, or accidents. Self replicating organisms can not happen with so-called self assembling atoms. Self replication is very, very complicated. This too doesn't just happen willy nilly. The sequencing of amino acids is beyond explanation. You do know that misfolding proteins, or amino acids in the wrong position of wrong slot causes CANCER. Also, why didn't the folding proteins for so-called first life, not decay right after they were formed at the molecular levels? You didn't know? There is no frame work in existence to where life can be traced back to dirt. This is the great lie being told. It doesn't exist. If you enjoy letting these men or pseudoscience evolutionists priests lie to you, and to do your thinking for you. Then that is your fault in allowing these men to hijack your mind. That is your choice. You can be a lemming and a follower of men if you want to. Not me. I am to smart for that. === Evolution = Self Assembling Atoms = Impossible ====

@kwimms

Жыл бұрын

@@PinataOblongata Check your shoe size... add your age and you will find your IQ. Everything you said above is nonsense. You have not seen any of it yourself and are just a parrot babbling away in your Fallen State of ignorant intellectualism.

@PinataOblongata

Жыл бұрын

@@kwimms sorry you're emotionally upset about what the evidence shows, but reality doesn't care about your feelings. If you don't understand the evidence, perhaps avail yourself of it.

This channel is gonna be another classic in the scientific KZread side.

@matttzzz2

Жыл бұрын

Aaaaand its dead

@tiberiusG

Жыл бұрын

He is likely quite busy. He works for a company called Simbiotic Software, where he develops and designs interactive simulations and content for electronic biology textbooks. This software is used in universities worldwide. As much as I would love to have him publishing world class content here on youtube for my consumption, his genius for quantitatively understanding molecular interactions is needed more in academia, where it can be applied to rigorous curriculum.

@muskyoxes

Жыл бұрын

@@tiberiusG I was going to say, "who would master such beautiful graphic presentation and then stop after two videos?" It makes sense if such mastery is his job, but he's doing so much more here than mere images in textbooks or papers. This should be part of a educational series on blu-ray

the complexity of organic life is mindblowing. All this is happening in one single cell, of one single part of a body full of millions of cells with different functions, every single milisecond. And it all evolved from a single first cell just by random iteration. it feels like it simply shouldn't be possible, but here we are. it's amazing.

@KerryKim

2 жыл бұрын

Agreed! I loved working on the visual system as it is mindbogglingly optimized and well evolved to the task of detecting light over an enormous dynamic range.

@gigigigiotto1673

2 жыл бұрын

yeah, the bruteforce method never fails, even if it took million of years to develop a complex living organism

@gigigigiotto1673

2 жыл бұрын

@@dean-alex-bolton4928 hah, i almost fell for it! You should really specify when you make a joke

@MagicToadSlime

2 жыл бұрын

@@dean-alex-bolton4928 Whether or not you call the forces of nature "God" doesn't hinder our ability to study and understand them/it. If anything, it's just a lazy cop-out; people are figuring the universe out, whether it's "Natural" or "God" makes almost no difference (in my mind they're one and the same)

@MagicToadSlime

2 жыл бұрын

@@dean-alex-bolton4928 Look, it's a non issue. If the greatest minds in theology, philosophy, and all branches of science couldn't reach a consensus after thousands of years, I don't see how it's even feasible for you to make such a claim. It's conjecture and you aren't even aware that it is.

I honestly don't know what to be more astounded about: 1. That this occurs 2. That we could possibly understand it 3. That you're able to describe it so beautifully. The amplification of the energy of a few photons into our visual sense of a scene taking place in the world is so incredible. I had heard that our ears can distinguish vibrations in air the size of half a hydrogen atom (which I hope you will do a video on). That amplification is also mindblowing, but I hadn't considered it for light before.

@kwimms

Жыл бұрын

The story telling. I am astounded about the storytelling. Amazing.

@28704joe

Жыл бұрын

It speaks to the power of natural selection.

@jimmybrice6360

Жыл бұрын

i am astounded that we work at all - the complication is immense

@kennethbransford820

Жыл бұрын

@@28704joe === Not natural selection, but design is the reason for your existence. There is no other way that it could have happened. === Evolution = Self Assembling Atoms = Impossible ====

@28704joe

Жыл бұрын

@@kennethbransford820 "design is the reason for your existence" sorry the answer is not that easy, seems like you are looking for a God. Go back and do some reading on the evolution of life. Read up on a guy named Charles Darwin.

Amazing animations and descriptions, perfect unison of media for explaining molecular biology.

@KerryKim

2 жыл бұрын

Thank you!

@s0meus3r

Жыл бұрын

​@@KerryKim should we expect more videos? (It's a masterpiece, thank you so much!)

@kwimms

Жыл бұрын

Yeah... just like a cartoon. Just like a cartoon.

I had no idea that the process of vision was so complex and interesting. What fascinates me the most about all this is that while I am watching your video, what you are explaining to me is happening in myself.

Absolutely amazing animations and easy to follow explanations. I have always assumed that the many biological processes look exactly like this but seeing it so clearly is so beautiful. I would love more videos just like this one, related to biophysics. For example how do other homeostatic processes in the body look and function on this small scale. Keep up the good content.

@TheStringKing7

2 жыл бұрын

Also I think you would get more traffic to your videos if you try to make the title and thumbnail more accessible and clickbait-y, but in a good way. For example, this video's title "Phototransduction: Amplification from molecule to cell" is a bit too technical ... Checkout Veritasium's videos on clickbait and taking advantage of the youtube algorithm.

@KerryKim

2 жыл бұрын

Thank you! Good points. I've changed the title and thumbnail to be (hopefully) a little more welcoming and less technical.

@SaeedNeamati

2 жыл бұрын

@@KerryKim the point is, you truly deserve millions of subacribers. I'm on KZread for mabe 7 8 years now (consumer) and I know a lot of channels. Your content is worthy. The key is, continuity + welcoming titles.

absolutely loved this eloquent teaching of yours, kerry. im excited to see and learn more from you!

How the hell do you only have 42 views. This is so great!

@KerryKim

2 жыл бұрын

Thank you! This is a new channel, so it doesn't get much traffic. Hopefully things will pick up after school starts for more students.

These Sims must have taken ages to finish! Great stuff

Please keep making videos. Your animations are some of the best I’ve ever seen and you do a fantastic job explaining the concepts. I work as a biology tutor and I will 100% be sharing this video!

these animations made me realize how complicated my body is and how much movement is always going on, amazing

I literally watched 5 videos and reread my book like 3 times to try to understand this concept and all the videos were either lacking labels or lacking visuals. This one actually made it slightly understandable. Thank you. Difficult concept to explain and show, but you did a great job.

People say there is beauty in simplicity, I would say there's also just as much beauty in complexity and this whole process has an awe-insipiring amount of complexity and it's just a simplification!! And of course this was an amazingly well put together video! Beautiful visuals and crystal clear explanations! Great job!!

Thanks - really great. The more we understand these processes, the more we realize, what a great accomplishment sentimental life really is. And, in the same time, how evolution left its trace in each of these (quite complicated) processes. This is all not necessarily an absolute optimum - but a lot of local ones, improved step by step, very old "solutions" left in place, even if these sometimes seem a little bit odd (like the place of the light sensitive membranes on the back side of the retina).

@charlesgallagher1376

2 жыл бұрын

Life is a sentimental journey.

It’s insane how complex and beautifully orchestrated this all is. And it’s equally impressive that science has figured out these processes.

Intuitively, I have always thought that the vision process was instantaneous. but after seeing your explanation I realize that it takes a certain time from when the light hits us until it reaches our brain, imperceptibly, very little time, but something. my mind lives nanoseconds in the past. Amazing. thanks for the video

I love channels that produce just a small number of high-quality videos. This was really excellent.

Such an underrated channel, can you explain how this happens in cones of different types? How do rhodopsins respond to different wavelengths(if that’s the correct question)? Thank you!

@Yoda2000ful

2 жыл бұрын

I am not a biologist, but one can speculate that the distance between the "plates" seen in the animation (surfaces where rhodopsin were floating) is crucial. Keep in mind that light is an EM wave, so the described distance may affect which wavelengths are absorbed and which are not. Maybe someone can confirm this hypothesis.

Please do more videos if you can! You are great at explaining these concepts and the visuals help a ton!

It amazes me that this system works fast enough with my brain to make me not drop my toast in the morning.

I hope you will keep making this kind of videos because they are truly remarkable, both in clarity of the presentation and in the amazing animations. Thank you very much for your effort!

I love the animations and the colour coding, it makes it so intuitive to follow what's happening Thank you!

Fantastic video. Thank you Kerry. The animations are an amazing way to make concrete concepts that might otherwise remain abstract for someone with casual interest in the topic. You've got my sub!

I really appreciate the videos you have made. Not only are they rich animations of biology but also food for the soul.

Keep the fantastic and informative content coming! You are a natural at this, and I look forward to your future videos.

Stumbled upon this and previous video - love the pace, animations and narration. Very good demonstration of complexity of processes within our body, thank you!! Hope to see and learn more! I’d be very interested in learning this process/sequence of events: what happens between the time I think/decide to lift a thumb up to actual moving the thumb up

another channel that deserves much more recognition

it's a shame there hasn't been more videos. this is incredibly interesting, and he is very good at explaining it to laymen. the animations are perfect! even the low quality is of no concern, the writing and dictation are perfect, and the information is concise and to the point. I subbed just in case there's more in the future.

@Misslayer99

7 ай бұрын

I just noticed this 😢 yeah it is a shame! I'm studying neurobiology and this video did a fantastic job explaining. Much better than anything else I've seen/heard. I was really hoping he had a whole series!

These videos are so intriguing, we're loving the very detailed and robust explanations. We hope you upload more the future, as your two videos so far have been very enjoyable to watch

Brilliant explanation! Best I've ever encountered out there! Thank you, Kerry!

I just discovered this channel and it's the greatest example of a hidden gem. i'd be so interested in the maths and physics part. looking forward to future videos.

Absolutely phenomenal animation, I have been studying this as a hobby for 15 years, never have I seen diagrams and animation so well constructed with a sense of time flow of the stepwise actions. Thank you

I subed in less than 1 minute. Right-to-the-point, no bullshit, no fancy cartoons, pure education and gold content. Please keep going.

Please return we need more of these!!

I'm so glad I found this channel, this is such great content! Thanks for producing this.

yessss please do more this is channel is extremely fuckign underrated the animations take it the next level and i cand actually understand what hes talking about with them

Awesome visuals please keep up the good work, huge channel in the making

Your two videos were probably the most interesting things I learned about myself in years. Thank you very much for this well thought presentation and those striking animations! This kind of content is really underrepresented on KZread and I hope you'll get the attention this effort deserves. Thank you again and be well! =)

Thank you for this Mr. Kim… you’ve created an absolute symphony of images & narrative which beautifully presents the subject matter I subbed & am looking forward to seeing your channel thrive :)

Kerry Kim: your presentation is absolutely amazing. Thank you so much.

absolutely gorgeous explanation and animation! thank you Kerry, this is a gift!

Indeed, Kerry please make more of this awesome content!

My God, this channel is mind blowingly amazing. The single best explanation and presentation about the topic I've seen! Very much hope to see your channel get more recognition!

Your animations are amazing and your videos are extremely informative. This channel is going to be big.

WHERE ARE YOU??? Those astonishing animations should not end, please do more, biomedical students need you 😭

I have a feeling this channel will get very big in a few years

What an amazing overview, an animated visual tour of the photoreceptor rod cells inner mechanisms... Now thanks to your explanation I am surprised I can even see enough to write this comment. Such complexity, it is mind boggling imagining this even works 😌

I am extremely impressed by the two videos you've put up so far, and hope to see many more like them in the future. You've found a very good balance between simple, clear explanations, which give a good broad picture of what's happening, and the actual specific mechanisms occuring within the cells and proteins. And all while maintaining a clear and easy tone, making it very easy to follow and pay attention. I very much hope to see more videos from you in the future :)

Please, PLEASE make more videos. This was such an excellent explanation! You have so much to offer the world, and I appreciate the gift of your knowledge. Thank you.

AMAZING video! I’ve been looking for content that covers how human sensory organs work from an engineering perspective forever. Instantly subscribed.

I always wondered what happens to ion channels in presence of random collisions between dynamically moving molecules. I always wondered how they find each other. Simple answers like affinity didn’t let me imagine it. Finally a nice video to visualise it. Many thanks. A much needed visualisation.

Thank you Kerry Kim for this work!

That was fantastic. I've never exposed myself to this before and I love it. Thank you.

Thank you kindly, Kerry. This is a fine work

Thanks Kerry, for producing this outstanding presentation. You are gifted in your understanding and in your ability to convey that understanding to others.

Phenomenal channel Mr. Kim!

Pretty amazing stuff. Nice to see some discussion on the random thermodynamic properties of protiens instead of the magically guided nanomachine we tend to see.

I hope your vids quickly pick up views, the manner in which you deliver the info is great

Absolutely great video! Thanks for making it!

Great video, absolutely dig the animations!

the animations are a cut above standard molecular representative animations, but also the narration that these supplement is so clear. amazing job!

Amazing video! Great visualisations, really helps bring molecular biology to life

A beautiful explanation of a beautiful phenomenon!

I teach AP Biology and this was a great example of to show cellular communication. The visual you've created is absolutely top quality. Please make more!

This is absolutely brilliant and lays the concepts out in an intuitive form that anyone can follow. Keep it up. Thanks.

Mr. Kim, thank you for this amazing illustration.... 🙏

I wish you had hundreds of these videos. Thank you

Thanks for the animations! It's really helpful to have visual memory of the process - I'll remember how a rod cell amplifies a single photon's signal forever.

Amazing job, I'll be waiting for your next video!

that might just be the very best explanation i have seen on this topic. Awesome!

This is fantastic video - thank you so much for making it. Both your explanation and the animation are so engaging and clear that it was a real pleasure to see it and come away feeling like I have a good understanding of a somewhat complicated process. I think I speak for most when I say that I hope you produce more videos.

I love this. The visualisation of the process of detecting light in the eye really helped me to understand what you were saying. I would love to learn more about this subject with you. Please do post more videos if you have time.

Just amazingly well explained, videos like this are youtube jewels and justify the existence of this platform. Thank you and congratulations.

Great video! And this complexity and beauty appeared absolutely randomly just within 1 billion years. Yeah, right.

Loved the animations with the explanation! Thank you

That is such a great illustration of how our eyes work. Can’t wait for new videos 👏

please post more. this is fascinating.

My god this was one of the best videos I’ve ever seen

Amazing video. I love the animations and the explanation is very clear. Thank you for sharing this for free on KZread.

thats so freaking cool, like mind blown. btw nice animation and explaination, it was quite fascinating

Wow! Congratulations for your channel. Your explanation is very clear and intuitive. Your work with the animations is impeccable. Thank you for this material.

I absolutly love animations that show biological processes at a cellular level. please do more

We need more episodes, this was mind blowing!

Amazing! Thank you very much for this! And awaiting more videos from you! Subscribed!

You are an amazing teacher. Thank you for your work.

I know this is only your second video but it was immensely educational and very interesting. I hope you continue to make videos like this in the future. Thank you

This was awesome can’t imagine the effort put into making of it

Amazing video! Normally I binge space and physics videos, but this video is turning me on to biology sciences. Very eager to learn more.

Thank you Mr Kim for another extremely interesting video. So our vision has quantum sensitivity. Amazing!!

Instant subscription. Great work on everything I hope to see more

That's a marvelous process and a outstanding work explaining that to us. Thank you.

You're an excellent teacher, man. This is the best explanation of phototransduction that I've had. I'm about to find out what other eye-related lessons you've got.

@GemstoneActual

Жыл бұрын

Dern; only the two videos. Still: good work.

may the algorithm gods bless this channel; this video is absolutely amazing

Amazing video; thank you so much for sharing these wonderful visualizations.

Oh this was great. I think I understood a lot of it, too. Avalanche cascades. I hope you produce more videos.

Love this video! Super fascinating

The only thing more amazing than the fact that this is how photoreceptive cells work, is the fact that we *know* that's how they work

This is a very stupid comment but it amazes me that any of this exists. Even the fact we were able to figure this out. Blows my mind