Phosphonium Ylide for The Wittig Reaction! - Organic Chemistry

Hey guys! You've heard me talk a bunch about the Wittig Reaction already but do you know actually how to make the Phosphonium Ylide that is used in the reaction? If not, check out this video that discusses the two important steps (SN2 and Deprotonation) necessary to create the awesome Phosphonium Ylide molecule. It's 8 minutes but it will go by fast, I promise ;). Also if anyone is interested in private tutoring either in person or via Skype, please contact me through my Orgo Made Easy Facebook page or email (FrankMWong@gmail.com)
The Wittig Reaction Made Easy!: • Wittig Reaction + Ylid...
Z and E Alkene Products Explained: • The Wittig Reaction's ...
The Wittig Reaction Mechanism Made Easy! (Funky Box): • The Wittig Reaction Me...
Wittig Reaction Bloopers/Outtakes: Coming Soon
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Пікірлер: 45

  • @mattspyro
    @mattspyro9 жыл бұрын

    videos are sooooooooo much better than my class!

  • @AoiTheLaughingMan
    @AoiTheLaughingMan8 жыл бұрын

    It's surprisingly hard to find a reaction mechanism this well constructed. Thanks.

  • @linatorres8774
    @linatorres87749 жыл бұрын

    Thank you so much!! You are truly great at simplifying the concepts!!

  • @alexisiverson686
    @alexisiverson6866 жыл бұрын

    Clear and organized explanation! Thank you! 🙂

  • @valdisjonsdottir5184
    @valdisjonsdottir51846 жыл бұрын

    Brilliant video, thank you so much. Very clear and well explained, subbed

  • @dattadongare2330
    @dattadongare23305 жыл бұрын

    Thank you for uploading video Very simple to understand

  • @henrrylanuez2733
    @henrrylanuez27338 жыл бұрын

    Thank you so much, this was super helpful for me.

  • @gracekinskey7288
    @gracekinskey72888 жыл бұрын

    You rock, thank you for these videos

  • @CartesianFirstPrinciples
    @CartesianFirstPrinciples10 жыл бұрын

    You are awesome at this! Thank you so much!

  • @OrgoMadeEasy

    @OrgoMadeEasy

    10 жыл бұрын

    Thanks Brian! I'm glad you like the explanation. It just clicked how simple it was actually one day for me in a tutoring session and I just wanted to share it with everyone.

  • @harveenkaur4684
    @harveenkaur46846 жыл бұрын

    Very helpful! Thanks!

  • @bushroni4893
    @bushroni48932 жыл бұрын

    Good education vidios ... preparing ylides 👍🏻

  • @lexiw9243
    @lexiw924310 жыл бұрын

    Thx for uploading so many useful videos! Hopefully u could make more Orgo 2 videos later on.! And it would be best if u could leave the board alone for a sec since i wanna take a snapshot of all these notes !! u r so good at teaching, keep it up!!

  • @OrgoMadeEasy

    @OrgoMadeEasy

    10 жыл бұрын

    Lexi W Haha thanks for the support! Yeah more Orgo 2 videos is definitely a goal but it'll just take some time =X. Gluck in the meantime ;)

  • @carlosgalvezrivero54
    @carlosgalvezrivero547 жыл бұрын

    very helpful!

  • @surat8591
    @surat85916 жыл бұрын

    Thank you so much!!!!!

  • @ranjitgogoi411
    @ranjitgogoi4115 жыл бұрын

    useful video👍

  • @liy3036
    @liy30368 жыл бұрын

    Nice video !

  • @joyliu7342
    @joyliu73425 жыл бұрын

    Thank you!!!!

  • @sarahhhchaaa
    @sarahhhchaaa10 жыл бұрын

    Your video was very simple and east to understand, thank you! Except I have one question about the alkyl halide. You listed that Fluorine could be one of the halogens for the SN2 reaction, but I thought Fluorine was a bad leaving group because it's rarely observed.

  • @OrgoMadeEasy

    @OrgoMadeEasy

    10 жыл бұрын

    Ah good catch! Fluorine is not so great of a leaving group so you'd probably see either Cl, Br, I as the halide. Sorry about the late response!

  • @cayleeluden3878
    @cayleeluden38789 жыл бұрын

    Hey! Really nice video.. Just wondering where the halide goes.. especially when you have a stable phosphonium salt, so one can deprotonate with a weak base such as NaOH, which forms water?

  • @OrgoMadeEasy

    @OrgoMadeEasy

    9 жыл бұрын

    Caylee Luden Thanks! And good question Caylee. I believe it's just sitting in solution as either a Cl-, Br-, or I-. (As someone noted F is not a good leaving group and should not be used). I don't usually see NaOH being used for this reaction, it might be good to check with your professor about that. I usually see NaH being used or a grignard organometallic like the other one I used.

  • @aakashkulkarni4979
    @aakashkulkarni49795 жыл бұрын

    Great

  • @HorrorbleTakes
    @HorrorbleTakes5 жыл бұрын

    Question: since Fluorine isn't the best leaving group in the world, would this reaction work with it?

  • @NitexLight8
    @NitexLight89 жыл бұрын

    Can water be count as one of the bases? Can you also use -OH or is it unlikely to have -OH by itself?

  • @robinrobin1610
    @robinrobin16103 жыл бұрын

    Excuse me sir could be kind enough to make a video for the preparation of Gilman reagent

  • @ahaa6235
    @ahaa62356 жыл бұрын

    thanks

  • @Pyrogore
    @Pyrogore10 жыл бұрын

    Hi Frank, what causes the base to be selective towards deprotonating the carbon adjacent to the phosphorous? Thanks!

  • @OrgoMadeEasy

    @OrgoMadeEasy

    10 жыл бұрын

    Hi Pyrogore! So the base is selective to deprotonating that carbon adjacent to the phosphorus because of the positive charge on the Phosphorus which makes it tug on the electron density of the carbon. This weakens the bonds between the C-H and makes the H more acidic and likely to react with a base and be pulled off. Does that make more sense? :]

  • @Pyrogore

    @Pyrogore

    10 жыл бұрын

    Makes perfect sense now, thanks Frank!

  • @OrgoMadeEasy

    @OrgoMadeEasy

    10 жыл бұрын

    Perfect! Glad to hear :]

  • @meamisano
    @meamisano8 жыл бұрын

    I don't understand where the extra Hydrogen from the carbon chain ends up that was replaced by the protons from the hydrogen part of the base?

  • @nyimansatanjie2524
    @nyimansatanjie25243 жыл бұрын

    Respect with thanths

  • @dhwaneetrathor7061
    @dhwaneetrathor706110 жыл бұрын

    phosphorus is a penta coordinating element (pcl5) then why does it not make a double bond with carbon? what is the reason of the occurance of charge on c and p?

  • @OrgoMadeEasy

    @OrgoMadeEasy

    10 жыл бұрын

    True it is a penta coordinating element but in this reaction Phosphorus only has two spare electrons which can only form a single bond with carbon when it attacks via SN2 and kicks out Carbon's leaving group halogen. Phosphorus is positive because it was neutral before when it had 3 bonds and a lone pair before the attack. But then it lost an electron to carbon when it attacked carbon and formed a bond. Carbon becomes negative because it gained an electron from the C-H bond after the base pulls off the hydrogen.

  • @chemflo8089
    @chemflo8089 Жыл бұрын

    thank you so much, please be a teacher🤗

  • @muffetmissulena6540
    @muffetmissulena65407 жыл бұрын

    Ugh...why do O Chem teachers always over complicate things? Your explanation is SO much easier to understand!

  • @rajarshibose5122
    @rajarshibose51227 жыл бұрын

    sir why only sn2

  • @elvisnegro6052
    @elvisnegro60525 жыл бұрын

    Good luck with the "super"primary alkyl fluoride🙄

  • @manishmayank4199

    @manishmayank4199

    5 жыл бұрын

    Is it even a term in organic chemistry😅 I heard it just here

  • @Chrisx132
    @Chrisx1327 жыл бұрын

    they moved the like button...awkward... :/

  • @Stephenbashqier
    @Stephenbashqier7 жыл бұрын

    Very informative thank you! I cringe everytime I watch you though; you're a litle awkward

  • @mindoverbread1213
    @mindoverbread12138 жыл бұрын

    Thank you. Very helpful :-)