One thing we can all agree on, is the importance of high quality sleep and blood work, so I chose todays sponsors accordingly: 🛌 Use my Eight Sleep code "MPMD" for $200 off the Pod 4, or $350 off the Pod 4 Ultra: www.eightsleep.com/moreplatesmoredates/ ⚕ Use code "MPMD" to get 10% off my go-to "Complete Panel" blood test, with a lab review included to interpret the results: marekhealth.com/mpmd Feels good to be back. More podcasts and videos incoming! ------------ 🕑 Time Stamps: 0:00:00 - 0:00:50 - Introduction 0:00:50 - 0:05:32 - Why Paul Saladino Stopped The Carnivore Diet After 2 Years 0:05:32 - 0:08:41 - Is There Ever A Point Of Doing A Keto Diet? 0:08:41 - 0:11:21 - Why Paul Reached Out To Me To Do A Second Podcast After Seeing Me Speak With Peter Attia 0:11:21 - 0:17:36 - What Actually Causes Atherosclerosis? Paul’s Take On The Traditional Hypothesis 0:17:36 - 0:22:17 - Should We Ignore High LDL-C Or APOB? 0:22:17 - 0:25:05 - Paul Describes How Some Studies Suggest That Those With Higher HDL-C Levels May Be Less Likely To Get Atherosclerosis Despite Having High LDL-C Levels 0:25:05 - 0:25:26 - Paul’s Perspective On Why Many Doctors Aren’t Educating Their Patients About Metabolic Health 0:25:26 - 0:33:41 - "Ignore Nutrition Just Focus On Exercise" 0:33:41 - 0:37:55 - Sponsor: Eight Sleep 0:37:55 - 0:39:02 - The Most Important Lab Tests For Avoiding Atherosclerosis 0:39:02 - 0:42:53 - Is It Possible To Get Atherosclerosis If You Have A Fasting Insulin Of 3 uIU/mL Or Less? 0:42:53 - 0:46:27 - Familial Hypercholesterolemia (FH) And Why It’s A Phenotypic Diagnosis, Not A Genotypic Diagnosis 0:46:27 - 0:49:41 - What Happens When You Replace Saturated Fat With Linoleic Acid? 0:49:41 - 0:52:38 - How A Pure Carnivore Diet Affects Thyroid Metabolism 0:52:38 - 0:56:45 - Can Someone On A Keto Diet Long-Term Develop Atherosclerosis Despite Having A Low Fasting Insulin? Dave Feldman’s Lean Mass Hyper-Responder Study 0:56:45 - 1:00:56 - How Paul’s Perspective Differs From Dave Feldman and Shawn Baker • The Baseline Data From The LMHR Study Paul Mentioned: twitter.com/realDaveFeldman/status/1733387107610063195 1:00:56 - 1:03:55 - What Is APOB And LP(a)? 1:03:55 - 1:06:44 - Sponsor: Marek Health 1:06:44 - 1:10:21 - How Long It Takes For Plaque To Develop And Show On A CT Angiogram 1:10:21 - 1:13:46 - Why Paul Uses Proxy Biomarkers In Atherosclerosis Data Analysis To Discern Insulin Sensitivity 1:13:46 - 1:18:14 - Does Paul Think It Is Ever Justified To Take Lipid Lowering Medication To Avoid Atherosclerosis? 1:18:14 - 1:20:13 - How Should You Track If You Are Developing Atherosclerosis? 1:20:13 - 1:45:27 - Lipid Lowering Medication Risk-Reward Analysis. Will Lowering LDL-C Impair Quality Of Life, Regardless Of The Medication Used? Do Adolescents With Hypofunctioning PCSK9 And Very Low APOB Have Impaired Development Cognitively Or Structurally? 1:45:27 - 1:47:39 - If You Don’t Lower APOB But Want To Track Plaque Accumulation, Is The Dose Of Radiation From A CT Angiogram Concerning? 1:47:39 - 1:56:45 -Why Certain Tribes Have Lower Rates Of Cardiovascular Disease Than The Average Person. Should Or Shouldn’t We Copy What They’re Doing? 1:56:45 - 2:16:17 - The Lowest Hanging Fruit For Avoiding Atherosclerosis And Evaluating Your Risk ------------

@frost15693

2 ай бұрын

balls to the wall supra-physiological posting schedule has my dopamine out of the reference range

Derek is praticing a so high level of broscience that he could be considered a professor. A brofessor.

@blindsey7807

2 ай бұрын

Bro

@taylorstuch1469

2 ай бұрын

His understanding is very impressive

@Magneticlaw

2 ай бұрын

Just so you have everything under control, that's what's important, since you obviously have the wisdom of the ancients at your fingertips.....

@ryanleahy6111

2 ай бұрын

Yeah he cooked w this comment

Thanks for having me on the pod, Derek. Hope the conversation is helpful for people. I know I talk fast, will try and slow it down in the future!

@connorgray2896

2 ай бұрын

It was a good convo. Remember Socrates said there is nothing better than leaving a conversation having been refuted. I won’t go as far to say you were refuted but I think derek did raise a lot of good points objections and this can only make you grow more, as you mentioned. Appreciate you mate, feeling great on animal based :)

@hyperresponder9362

2 ай бұрын

@@connorgray2896 I was actually surprised at the end when Derek dicussed a possible scenario of a perfectly healthy individual with high ApoB and supplementing with the latest and greatest lipid-lowering drugs. I think the obvious refute would be: 1. A healthy individual should always strive to avoid pharmaceutical drugs. All drugs have side effects, and if ApoB alone is bothering you, add some carbs to lower it. No need for drugs. The mere thought of taking drugs as part of a healthy lifestyle is distorted. 2. Many of these lipid-lowering drug outcomes only mention CVD mortality and fail to mention all-cause mortality. The reason being they don’t improve it. So you’re less likely to die of a heart attack talking these drugs, but you’d still die at the same predicted age from something else. These drugs do not work as most people think. 3. The lipid guidelines, the drug RCT’s and outcomes are of course all sponsored by big pharma, and you should be very wary of that. You cannot trust the reported data as-is.

@gggXIII

2 ай бұрын

Derek really asks great questions. Even tho i don't agree fully with stuff u say Paul (i disagree with quite some), I think u can have very high quality debates defending your points and i don't think your opinion is as contraversal as a diet that u do acording to that opinion. Even tho you are contraversial figure, I dont see you even near the pseudoscientific team foil, where some people try to fit u. I think u should do less influencer type of content where you sometimes sound pseudoscientific and do more of long debates and videos like this one. Great work both of you💪💪

@4DTravelr

2 ай бұрын

​@@gggXIIIHe's not controversial, he is promoting a balanced, non-extreme and sustainable diet that excludes all processed and harmful foods. He is exposing that sugar is not bad for you, while at the same time emphasizing that meat and animal foods are the healthiest and most nutritious. In other words, he's not joining one of the diet cults - the system wants the cults to argue with each other forever and never reach the truth. IMO Paul it near the truth and so he's being labeled controversial to throw the peasants off the scent.

@brockashsfrund

2 ай бұрын

Debate Bart

Derek, please start hosting debates. It is the only way people that disagree but cannot sit down to talk can do it. The respect they have for you makes it doable

@hamishh3865

2 ай бұрын

yeah - homeboy is basically saying here carnivore or even keto can't be followed by anyone long term!

@tendiie

26 күн бұрын

Derek hosting 2024 presidential debates

Derek should host his podcast in the sauna!

@moredreamsmorecreams

2 ай бұрын

Yesss

@Themilkman95

2 ай бұрын

Naked or not naked?

@jfb.8746

2 ай бұрын

@@Themilkman95 Oh cmon, men of culture, we know the answer!

@dillonclaborn795

2 ай бұрын

A Roman Bath House

Excellent conversation. Thanks for hosting it, Derek.

Upload schedule is improving

@veilmontTV

2 ай бұрын

Burn out is real

@Dan-lq6dg

2 ай бұрын

Anabolic amount of uploads

@NofirstnameNolastname

2 ай бұрын

@@veilmontTV The guy is just making bank with his companies. No time for YT

@humanspecieseradicationmedia

2 ай бұрын

An efficacious dose of uploads

@ronnie7100

2 ай бұрын

Supraphysiological levels of uploads streamlined to a relative time period.

Really good episode, I appreciated pushing him on the risk reward analysis in the spirit of genuine curiosity

Thanks for the pod! Love both you guys, learn so much all the time. Great to hear from someone whose continually growing in their views and beliefs. It’s on the listeners to evaluate and discern what would work best for themselves, in their own life. Dude is just talking about his journey and how his beliefs have evolved, he’s not responsible for your own choices.

So, uh, in practical use let me see if I got this right: 1.) Don't be overweight 2.) Do cardiovascular exercise and lift weights 3.) avoid excess processed sugar 4.) eat a varied diet that doesn't completely eliminate any macro or micro. 5.) Past a certain age get a test from doctor to see how much plaque you got going on. Did I leave anything out?

@blackpalacemusic

Ай бұрын

Or eat a plant based whole food diet, lift iron, run, dance and stretch. Don't drink alcohol, don't smoke.

@aliciaserrano9698

Ай бұрын

@@blackpalacemusicthis 👆

@JoeyDNetsfan

Ай бұрын

@@blackpalacemusicplant based? No thanks

@FirstnameLastname-pe5ib

5 күн бұрын

​@@blackpalacemusicThat's one way to go gay & be weak & ugly in old age.

I double-checked my audio almost every time Paul talked to make sure I didn't accidentally hit 2X speed

@dustinmartin4621

Ай бұрын

I swear I just commented the same thing 🤣 so weird lmao

@CoreLabb

29 күн бұрын

Same. I slow it down when he talks.

Heart health is one thing with this diet, but Kidney and liver health is also what I’m looking at. Whatever is the best diet for my organs is what im doing. Whether fruit+meat, or mediterranean, idc, I just don’t want to die for a dumb reason

@gp7110

2 ай бұрын

This is why Paul is outspoken about the benefits of insulin and what the spikes actually do for your kidney function. Keto and carnivore people skip and bullshit this factual information from Paul

@Cptn.Smoker

2 ай бұрын

Death smiles at us all, all we can do is smile back. - Marcus Aurelius

@redpillthinking6043

2 ай бұрын

​@@gp7110 A large bolus of protein will also spike insulin. Paul did carnivore wrong.

@gp7110

2 ай бұрын

@@redpillthinking6043 not by much that is a fact, so much more subdued than an actual carbohydrate of which his choices of raw milk and fruit are so ridiculously low on the spectrum I’m amazed he gets so much flack

@Rhodochrose

2 ай бұрын

​@@gp7110you don't need much

You should have Mike Fave on to talk about this

@Toucan47-wq2wh

2 ай бұрын

I found Mike and Saladino's video on sugar helpful for understanding many of flaws with low carb.

@BioenergeticFarmer

2 ай бұрын

While I appreciate Saladino promoting some of the bioenergetic ideas it would be nice to see someone at Mikes level of understanding explaining why carbs can be very important. Saladino doesn't seem to be operating at a high level of understanding on the subject.

@TheOneMastodon

2 ай бұрын

Look kids, it's a carnivore cope ! They do this when one of their gurus backpedals and admits the truth; hop onto another bandwagon.

@Emily-ji9ng

2 ай бұрын

Yes! Get Mike on!

@recommendeddailyvalue

2 ай бұрын

@mikefavescience

This is a great discussion.

Crazy that I didn’t even know I missed your videos until you posted the first one back after an 8 month hiatus!

I'm getting info from this so this isn't a dig on it as a whole, but it seemed hard to follow because you and Paul bounced around trying to find common ground in different areas. The conversation in general had a back and forth feel to it. Did you both have an outline for the show? If you need someone to Google info on the side during podcasts I could be available. Regardless, love what you do here and for doing the Marek thing. I love that Paul keeps trying. We need people to be fringe to find the limits of what we know so we can gather more info and make more informed decisions in the future. Cheers!

@workhardt8080

2 ай бұрын

True but I do feel the very last segment of the podcast was kind of a saving grace after they got off that specific back n forth and had time to process what the other person was trying to get it at they were able to tie it together a lot better, hope every one watches the whole thing and doesn't miss that part. At the end of the day we just need way more conversations held with both sides of the community, that's one thing I respect about Paul he has always tried/is willing to talk to anyone on air about the topic. Really wish Peter Attia would agree to do a show with both him and Derek so there isn't this kind of proxy debate where its hard to get super granular because of not knowing every little detail about what the other person actually believes/advocates for. That's the best outcome for us the viewers who just want to learn.

Would love to see a discussion w/ Derek, Peter, Paul and Simon Hill!

I don't have a fear of death, but at the same time, I'm not trying to speed up the process. Accepting the fact that death is simply part of life, its not so bad. Focus on living rather than the inevitable outcome. Take care of yourself and your loved ones and just enjoy the process as best you can. That's my outlook at any rate. Cheers!

This is one of the best examples of a constructive, healthy, respectful debate/discussion. It’s also one of the most meaningful discussions for people living - or trying to live - in 2024.

This was a brilliant podcast episode! 👏 One question, when is the delt modified lab coat returning bro? 😆

Derek definitely shooting ropes with this upload cycle.

Here we go ! Been looking forward to this all week Derek, thank you brotha !

Good podcast, looking forwards for more content for you, thumbsup

Great show

I can't even listen to this guy just knowing the fact that he truly believed that Liver King was natural!!!

@thacrackpac

2 ай бұрын

They were close business partners and knew each other personally. Bro got tricked by a pathological liar but he still a good soul.

@xiRePeNTx

2 ай бұрын

wait you mean derek or the other guy on podcast

@teni8943

2 ай бұрын

oh no!

@yog4042

2 ай бұрын

THANKS FOR THE WARNING LOL IM OUT

@xiRePeNTx

2 ай бұрын

@@RoMaRobMarq thx bro lol I was confused 😅

Good watch, just finished

Can’t wait to watch this. You two are my fav!

Wholefood diet, meat, veggies, fruits, wholegrains... Probably the best diet, don't need to be extreme

@4DTravelr

2 ай бұрын

Paul promotes meat, fruit, honey, raw dairy, and organs. It's not very extreme either. Only difference from what you said is no veggies or grains.

@Louis-qo7tf

2 ай бұрын

@@4DTravelr why no veggies or grains, there are fibers and nutrients

@4DTravelr

2 ай бұрын

@@Louis-qo7tf Fiber is indigestible. Veggies have non-ideal forms of many nutrients that the body often can't deal with so easily compared to the animal food counterparts. There are also at times anti-nutrients and oxalates. Grains cause alot of people issues including Paul. But if they work for you, then by all means (grains).

@Louis-qo7tf

2 ай бұрын

@@4DTravelr fibers is great for digestion, good bacteria’s eat fibers therefore your gut is healthy. It also slow down digestion, there lowers blood sugars spikes

@Louis-qo7tf

2 ай бұрын

@@4DTravelr why can we eat fruits but not veggies then?

It’s apparent who took their pre-podcast propranolol and who didn’t 🤣

Paul talks like 1.5 speed like he's used to being spoken over😄

Man, great talk. You asked good questions & gave him the stage to deep dive. Would love to hear him debate somebody else on these facts.

I like these two hour podcasts. I can work with my hands, listen, and not feel the need to touch my phone too much switching from video to video

Looking forward to this. Glad to see Derek back. When it comes to atherosclerosis & cholesterol I have no idea what to believe. Hopefully gain some insights here.

@connorgray2896

2 ай бұрын

From This convo I do think It makes sense to hedge your bets against high apob whilst also living healthy in all other aspects. If you can find a apob lowering med with little to no side effects then it seems the benefits far outweigh the risks.

Paul is the only person I have to put on slower speed.

Love this! Thank you!!!

Love that you two could sit down and speak through the nuances of nutrition and exercise! Sort of weird that Dr. Saladino was trying to paint the story that Dr. Attia only focuses on exercise. Regardless, glad you two were able to get over that hurdle and host a beneficial, public, open discussion on the rapidly evolving and complex field of metabolic health. Would be great to see more podcasts like this!

Dear god the amount of ignorance and/or shills in these comments is deeply depressing.

Who watched this and still doesn’t know what APOB is? 😅

@Superultera

2 ай бұрын

This guy. In fact, I don't think I took away anything of value from the entire conversation.

@Sk1pperCS

2 ай бұрын

LDL - Low Density Lipoprotiens (carry triglyceride and cholesterol to peripheral tissues from the liver) HDL- Carries cholesterol from peripheral tissues to the liver. (Not a risk factor for heart disease) ApoB - There are multiple different types of LDL lipoproteins all of which contain apoB(the protien bit) cholesterol or triglycerides would be the “lipo” bit of lipoprotein. The theory is that not all LDL Carries the same atherogenicity(plaque causing) But since all LDL contains apob it’s just a better way to measure all of the atherogenic particles compared to just getting an LDL-C (cholesterol) measurement. As for the types of LDL: you have vLDL, iDL, lpa Paul’s argument is that lifestyle changes are good enough to mitigate risk and that apoB (while being a risk factor) is not significant enough to hop on meds for when all other lifestyle changes are accounted for. As for Derek, he is more in the middle ground. Meds if outcomes are better vice versa. I think….This stuff can be tough to grasp honestly.

@jon0604

Ай бұрын

Apo B100 is the protein tag that is on VLDL, IDL, and LDL that allows it to be detected as such. HDL has an Apo A1 tag which distinguishes it. VLDL drops of triglycerides and becomes IDL then LDL.

@MsStack42

22 күн бұрын

@@Superultera He's a loony....

That mattress advertisement should have been a podcast all by itself.😅

I know it would be a big cost, but if you had an editor have little slides/annotations come up sometimes when referencing medical terms /conditions that are slightly less well known that would make these podcasts a whole new learning experience and way more accessible. Even just a pop up description of a term front time to time. I’ve been watching for 4/5 years now but there are times I don’t have a clue what they’re talking about

Went from Paul Steakino to Paul Saladino

@balarab1

2 ай бұрын

Fruitino lol, he doesn't eat salad.

@Steven_DunbarSL

2 ай бұрын

Honino 🤯

@MsStack42

22 күн бұрын

Shitino.

Im curious If Paul thinks type 2 diabetics should eat carbs and use drugs to decrease blood glucose a alternative to Strict keto for glucose control. Keto has had me at 4.7 A1c non-diabetic from 13.2 A1c Scorching Diabetic. since Feb 2020. Drug intervention "Insulin, Metformin, Invokana" kept me at 6.5 A1c diabetic with treatment.

@frontierlandfrank5314

2 ай бұрын

You were doing something seriously wrong if your A1c was still that high on insulin.

@philloder

2 ай бұрын

@@frontierlandfrank5314 Absolutely correct, I followed my doctor's orders of eating a healthy diet of Whole grains, brightly colored vegetables like tomatoes, red potatoes, carrots and lots of Juice, fruits and berries. The standard american diet, also known to kill people with extreme insulin resistance. Extreme Keto "Sub 15 Grams of carbs daily dropped 100 lbs, and allowed me to get moving again without joint pain. I have now gained 30 lbs of muscle in 4 year "Dexa scan verified @ 19% body fat and won't go back. currently I have the following specs @ 64 years old. 5'10" 190 lbs 48" chest, 16.5" biceps, 32" waist. Can deadlift 300 lbs, 36" box jump multiple times, Dips with added 90 lbs, chinups with the same weight. I still eat the occasional high carb meal on special occasions then work it off quickly. A few DewBerries are consumed daily, picked off my fence line when in season. The doctor now hates to see me as I question most things with info from derrick, Attia, Huberman, and the like. Click on my image to see a few "mainly silent" videos showing the effects of a clean keto lifestyle!

@4DTravelr

2 ай бұрын

Yes raw honey literally improves insulin sensitivity and also Kempner's rice diet cures diabetes lol

@frontierlandfrank5314

2 ай бұрын

@coomerkiller Paul acknowledged what that other person has said before

@joellachmann1529

2 ай бұрын

Raw honey

Excellent quality here from Paul

Now this is worth of thy time mi frend

You did not let that man say ONE word about seed oils. Masterful.

Save yourself some time: Derek believes that leveraging pharma in addition to a healthy lifestyle is worth the potential side effect profile, Paul does not.

This first time see the push back multiple times, not like being wrong but wanting clarification. Multiple pushes in forms of well what about this class of people? Think what sometimes see is a little ego from Saladino exploring figured out / edge of knowledge / and he sometimes wants to speak and say “well let me finish ok”. Think you pushed not only his ego, you made him have to go “I need to regather more” . It’s healthy. No matter how well we know something, it takes running into the right person to really challenge us. To make us learn more to know, we always have more to learn. I don’t care what title you have, if talk about it everyday. Someone is going to be a little faster, clearer, have a turn you didn’t fully consider. Derek made a high mind have to reach higher. Awesome conversation.

Good interview. I respect Paul's ability to interpret studies and share his knowledge about his health journey. People should be willing to put the time and effort into understanding their own personal health.

Is he talking in speed x2?

@JaPorchie

2 ай бұрын

It’s a rhetorical trick to make him seem smarter and his incredibly imbalanced views more legitimate

@Superultera

2 ай бұрын

Word Saladino.

@stevewerner5440

2 ай бұрын

@@Superultera Bro! LOL

@organicthug5220

2 ай бұрын

@@Superulterathis should be top comment. I get that he’s smart and all that, but usually when you are speaking to a broad audience; it’s best to dumb things down. He’s speaking like a lawyer. Jelking to big words.

@nickstrasser6173

2 ай бұрын

The Ben Shapiro “trick”

I think Derek needs to mediate a Paul /Peter pod

We’ve been prescribing statins for 20 years en mass - and CVD is still going up. I’m a pharmacist and know the science fairly well but just that fact alone tells you that the lipid model of CVD is at the very least incomplete and probably wrong.

@FrancisDietPodcast

2 ай бұрын

Not remotely .! And if u were you’d know that Focusing on keeping LDL oxidation as low as possible -> oxidative stress is main contributing factor to plaque formation. Which is the driver of arterial sclerosis

@TheAbsoluteSir

2 ай бұрын

That means that we live a more sedentary lifestyle and eat worse than ever, not that statins don't work.

@WideAwakeHuman

2 ай бұрын

@@FrancisDietPodcast yeah you’re making the same case - it’s about the environment in which LDL is present, not the amount of LDL. Thanks.

@WideAwakeHuman

2 ай бұрын

@@TheAbsoluteSir go back and look at the percentage of people that have high vs normal LDL and have cardiac events. And then look at the most recent data around statin effectiveness along with the relationship to dementia after long term use. Educate yourself instead of just believing what ur told by big pharma or some random dude on the KZread.

@jmizzonini

2 ай бұрын

@@TheAbsoluteSir WHEN THINGS GET WORSE, THAT MEANS IT WORKS! ok bozo. Also the trend in people doing physical activity has actually risen over the past two decades.

How do these people internally deal with the fact that they evangelized a diet they were CERTAIN were right, and convinced others to go on them, just to then drop the diet themselves?

@graychev

2 ай бұрын

I for one, admire people who change their mind upon new evidence. I'm not saying he's not a quack, though. But still.

@ed7590

2 ай бұрын

@@graychev Shouldn't that be a sign to not evangelize any system at any stage when it comes to personal health though? We could always be presented with new evidence..

@connietrumpf2037

2 ай бұрын

Live and learn. I commend him for paying attention to his body and what it needs and changing his mind. Everyone needs to be this way. Rigidity does not serve us

@ed7590

2 ай бұрын

@@connietrumpf2037 I didn't criticise him changing his mind. I commend that as well. Please re-read my comment.

@efrainmendez2623

2 ай бұрын

Well going carnivore is definitely not one bad thing to evangelize... Ideally if he stopped working out so much being always on carnivore he'd be perfect

I love this. I tried 100 diets and you really have to try it to see if it lives up to the hype. You really learn on your mistskes.

Conversation with Saladino and Attia together has to happen! Fans of both, would be a great podcast

Used to love this dude. Still appreciate him, but I don't like how he's transformed into your typical social media influencer

@Steve-ev6vx

2 ай бұрын

Yeah, like WTF? Podcasts with grifters...

@Har9000

2 ай бұрын

He's running a business

@czar17_28

2 ай бұрын

What’s the social media influencer part? That he doesn’t feel like carnivore is good anymorev

@ericlecours4208

2 ай бұрын

When I saw saladino had a smoothie named after him at Erewhon I was like shit. He’s more famous than I thought. I do feel great on his diet though. I did add in the “grey area” rice though and loving it the last couple of days. Feeling a lot stronger in BJJ.

@RyTrapp0

2 ай бұрын

...wat...

Got damn, Derek is a legit black belt in this shit. Im always stunned of his knowledge on such intricate topics

I think one thing that is always left off of these discussions is what should a person do if they are not metabolically healthy, don't have/are disposed to FH, and have high levels of APOB, and struggling thyroid? I believe this cohort of patient is very prominent in the US and it would be helpful to discuss from that perspective. I know several relatives that would fall into this group and wonder how I should encourage them. i.e - should they attempt a limited full carnivore diet to help get their metabolic health moving in the right direction? Is low impact cardio sufficient if that is all they feel like they have the energy to do daily?

Really good questions and pushback on suspect points, or rather statements that don’t address the other side. Seems like Saladino has a philosophy, not a rigorous worldview that reflects the best available research.

Guess who's back, Back again, Derek's back, Tell a friend!

it’s wild that this comes out at this time because like 2 and a half weeks ago i started watching Saladino’s stuff and taking it serious than before because i used to think he was a quack but im 100% on board now from thinking about it logically ive been on animal based for over 2 weeks and have felt 100 times better

@animalbasedguy9488

2 ай бұрын

At least there is one thinking person in the comments. It's a lifesaving diet in certain circumstances.

@Sk1pperCS

2 ай бұрын

He can be a bit extreme sometimes, but he is generally very educated and passionate about this stuff and means well. I love Paul’s work.

@Albrtd3

2 ай бұрын

Been on it a bit over a year. Just remember not to skimp out on the bone broth for collagens, and liver for all the other vitamins as well as your fruits!

Per the title, yes LAL can be a marker for heart disease. Depends are your particle size and LDL type. APO B is a way better marker for heart disease monitoring.

Does anyone know if Paul has got a Fructosamine test before?

Balanced diet for the win.

It's impossible to keep up with Derek and Paul while HIGH. Fuckin impossible

@aleccadena9061

2 ай бұрын

Bro I was experiencing this too lmao

@Fitnesstrainerka

2 ай бұрын

@@aleccadena9061 might have to run it back tonight with 75 mg thc. Maybe if I focus hard af I might keep up😅

@Magneticlaw

2 ай бұрын

Wait, they're high, or you are? Or both?

@Fitnesstrainerka

2 ай бұрын

@@Magneticlaw I'm high

Keep them coming

I have been pure carnivore 1 year and have monthly bloodwork. My electrolytes are always fine.

Atherosclerosis starts with lesions on the walls of arteries. Inflammation, poor metabolic health are probably main causes to this dysfunction . HBP, diabetes , insulin issues all are major contributors causing endothelial damage …. It seems focusing or treating the causes of the lesions is ideal to long term health. The body repairs lesions using cholesterol. The focus ( fundamentally) has been on ldl levels , higher being bad. I’ve yet to see an explanation that if you have a lesion , the person with an ldl of 150, vs 70, would send more cholesterol to the lesion for repair ( causing more “clogging”) vs the person ldl of 70? Thus the idea that “lower” = less clogging….. one would think the body sends just enough to repair the lesion whether the ldl was 150 or 70 ( or aboB being higher versus lower ). The idea that lowering ldl (apob) via pharmaceuticals stops/minimizes the repair of lesions ( microtears) formation and thus the level of “clogging” due to other causes of inflammation seems confusing. In a perfect world with no endothelial damage , does it even matter what your ldl level is ?

@Lozwave

2 ай бұрын

Risk factors for heart disease are smoking, drinking, saturated fat, trans fats, refined sugar etc. they damage the tight junctions of the endothelial cell wall in your arteries. This is because they are inflammatory products. Once the tight junctions are permeable then the body has endothelial dysfunction. However the nail in the coffin IS, exogenous LDL particles, the more you eat the more likely they are to oxidise within your arterial wall. Once they are trapped they never get out. Macrophages see them as foreign bodies and engulf the lipids, they begin to expand as foam cells until they finally explode. The internal lipids are further spread, more macrophages then arrive and see more foreign oxidise bodies and the cycle continues trying to engulf them. These lipids continue to become trapped unless you reduce the exogenous intake. Calcium and phosphates in the blood harden theses lipids and that is what atherosclerosis is, our number one killer. So there are risk factors like smoking etc etc but NO LDL DOES CAUSE HEART DISEASE, it is the number one critical risk factor. To answer your question though, you will still have atherosclerosis from high exogenous LDL, even without the risk factors, the critical risk factor is LDL

@Lozwave

2 ай бұрын

Our body produces its own cholesterol and we don’t need consume exogenous cholesterol to meet our needs. This is why carnivore is a fad and whole food plant based diets are not, a nutritionally complete plant based diet will always have better health outcomes than omnivores and especially carnivores assuming it’s whole foods and all macro and micro nutrients including amino acids are accounted for, high fibre, more variety, lower rates of cancer, heart disease and diabetes etc

@Rhodochrose

2 ай бұрын

​​@@LozwaveOur body produces its own carbohydrates and we don't need to consume exogenous carbohydrates to meet our needs. This is why modern agricultural diets are a meme and our ancestral dietary niche of carnivory is not. A meat based diet is nutritionally complete whilst plant based diets are lacking, thus why the majority those who try veganism quit in a couple years with the majority of those who quit citing health problems as the reason. More fiber is just more poo and gas, the rest are associative memes that don't even include carnivorous cohorts, not to mention the lack of scientific rigour in these associative studies

Dude, I fucking miss you!!

@Steven_DunbarSL

2 ай бұрын

I miss you too dude!

This was a great interview. I can see why Derek is so popular.

What do I do if I'm a truck driver... with no consistent sleep.. I exercise.. strength train 3 to 4 days a week.. eat non processed foods... walk.. but not enough... just a situation I'm in... Is my sleep pattern.. which is all over... does that mean I'm doomed?

More Plates Of Salad.

@anonymous134y

2 ай бұрын

didn't you know vegetables are bad for you? Turns out the Mediterranean diet is unhealthy after all.... lol

@dejansljivak66

2 ай бұрын

@@anonymous134y wtf is 'Mediterranean diet'?

Paul is that kid who hated vegetables so much as a kid he’s devoted his whole life talking about how unhealthy they are because his mom made him eat a broccoli one time 😂

@moun7ainc0w

2 ай бұрын

He used to be vegan

@johnweinhandl8890

2 ай бұрын

He’s my hero Trust your tongue There’s a reason humans hate eating vegetables

@Steven_DunbarSL

2 ай бұрын

​@@johnweinhandl8890Wait till you find out that vegetables can taste good 🤯

@Joost-qo9im

2 ай бұрын

@johnweinhandl8890 Guys, trust your tongue! There's a reason people really like sugar and cocaine.

@animalbasedguy9488

2 ай бұрын

Or like he said he was vegan and had really bad reactions like a lot of people do.

Nice pod

I am 56 years old. Been in the gym religiously for 39 years. I still train really hard 4-5 times a week for an hour or more (doing HIT) I went Carnivore 28 months ago, and had many, many benefits, but, like Paul, I had terrible cramping and frequent heart palpitations. I added electrolytes after a year and this still did not solve things. After 18 months I added some fruit. Nothing crazy like Paul, maybe 3-4 servings of fruit a day, mostly berries in a smoothie. This solved all my issues! My hypothesis is a little different from Paul's. I think that when you are super active and often depleting all of your muscle glycogen, via hardcore training or like Paul's surfboarding, and then not replenishing that glycogen via carb loading, especially after training, that these carbs actually are the transport mechanism to put the electrolytes into the muscle. The muscles become chronically electrolyte depleted and then the cramping becomes chronic. Anyway, some fruit fixed that. Recently I have been following Dr. O'Mara and now I am adding some ferments to my diet. I may try to lower the carbs somewhat and see if the original problem might have had to do with gut biome health.

Saladino was very defensive, lol. I'm glad y'all were able to work through that and come to an understanding and overall have a great discussion. I know he gets ragged on often, so its to be expected. You asked some tough questions for the sake of understanding as well as to help us understand and I appreciate you for that, Derek. For what it's worth, Saladino, my perspective is much more similar to yours as I believe carnivore is a tool that should be used to figure out what works best for each of us on an individual level. I believe a food journal is the key to determining what is the proper diet for each of us while using the carnivore style diet to heal as well as create a clean foundation from which to test various plants (veg/fruit) for side effects while notating how our bodies react to them. This will give us a great diet plan to follow that suits our needs, allowing everyone to drop the dogmatic approach. Its quite annoying to see people in carnivore forums get all bent out of shape with their dogmatic outlook which makes them easily comparable to the vegan crowd. In any case, I wish you all well on your health journeys. Cheers!

I think paul thought derek was trying to get him in a gotcha moment instead of being genuine.

@socrates2788

Күн бұрын

What makes you say that?

@zeno4538

Күн бұрын

@@socrates2788 he seemed irritated and defensive, I'll have to rewatch to give you specific timestamps

@zeno4538

Күн бұрын

@@socrates2788 he seemed irritated and defensive, I'll have to rewatch to give you specific timestamps

Angus Barbieri was not stationary in the hospital. And he never got electrolytes iv. He went monthly to his GP and got his blood tests. They decided to give him oral sodium, potassium and a multivitamin.

Why does it seem like I watching this on 2x speed when he talks 😂😂

Salidino is overhated his diet made me realise the reason i had gut and poopy di scoop issues may been due to plants, spices and seed oils (i was told just eat more fibre even though it made it worse) also adding organs like liver and eating more butter made me feel better

@partsunknown2852

2 ай бұрын

This diet has improved my life immensely, I’ve changed as a person. New goals, actual ambition and I’m noticeably sharper.

@ShreddedGenius

2 ай бұрын

@@partsunknown2852 blessed bro

@dubbstepl273

2 ай бұрын

For real it fixed my gut and bathroom issues, I don’t care if he’s a grifter or charlatan at this point, the diet works for me and I love it

@bumblebower1529

2 ай бұрын

Changed my life too man no more ibs chronic pain brain fog crp was 6 now it’s less then 1 no more asthma lost 100 pounds and am pretty fucking jacked now

@ShreddedGenius

2 ай бұрын

@@bumblebower1529 wow 100 pounds is crazy

I'm just going to throw this out there and say it. If someone uses a lot of "big" words, a lot of industry words (combo with the big words), talks fast, and at the end of a 2 hour conversation you still don't understand the claim or what's going on... you're probably being scammed. Or at the very least, you should be very skeptical of them. Or a combination of both.

@TheMasterblah

2 ай бұрын

99% of people that cannot or choose not express their ideas in simple ways should be looked at with scrutiny. The last 1% are just the super autismo geniuses.

@Dwhizzle

2 ай бұрын

I agree 1000%. The guy says about 500 words a second, and uses so many abbreviations and complex phrases it’s hard to keep track of him. At least to the average person. I feel like he keeps moving at an insane pace, so no one can actually follow what he is saying.

@balarab1

2 ай бұрын

Just cause you didn't understand it, it doesn't make any of what his said invalid. point out what his wrong about

@Themooman29

2 ай бұрын

@@balarab1 no no I understood him. But what I gave you was helpful life advise.

@Cptn.Smoker

2 ай бұрын

Meh …. I don’t understand the issue ? Eat meat fruit and honey .. drink milk and OJ… how is this controversial 💀

If I remember correctly that guy that fasted for a year was at some point given minerals, you mentioned it in the video covering him Derek. Also I'd imagine at the bare minimum he'd not some potassium and magnesium supplementation.

@Gengh13

2 ай бұрын

He took a multivitamin that I would guess probably had some minerals besides the ones in water.

THE GOAT IS BACK ON KZread 2024 MPMD

I stopped following this guy when he said he has no idea the liver king was on roids. Called him a friend then “distanced himself” from him after liver admitted it lol

I will never understand what's controversial about eating fruits, vegetables, and whole grains. Diets like carnivore completely miss one of the biggest advantages humans have - we're opportunistic eaters. Not saying you should eat twinkies, but cavemen probably would kill (you) for them.

@iiyyxxnn

2 ай бұрын

Just because you can doesn't mean you should.

@Steve-ev6vx

2 ай бұрын

It probably depends on the individual. We are all sooo different.

@iiam2214

2 ай бұрын

Well, I think Joe Rogan, Paul, and others have said that they have immune issues. Most people don't have issues eating rice or bread, for that matter. This helps a lot of people who have food allergies would be my opinion. I think people saw that it helps with fat loss, and people went on making careers out of it (liver king). Even Derek eats meat with carbs

@Sneedstein

2 ай бұрын

@@iiam2214 My issue with any 'fad diet' is the key component that they all use to promote weight loss is almost always cutting out junk food. If you're allergic to say, rice or grain, or whatever, that's a valid reason. It's when people who say they're on the keto diet, ignore that it's made as a treatment for children with epilepsy, where the kids will literally drink heavy cream as part of their dinner, and instead cut out junk food.

@Steve-ev6vx

2 ай бұрын

@@iiam2214 here was my experience. I struggled with my weight my entire life and it ruined my childhood and school/college years. When I stopped eating carbs and all the weight just fell off, without even exercising, it was easy to justify thinking carbs were the enemy.

➡ I've been listening to Attia, MPMD, Huberman, Shawn Baker, Saladino, Anthony Chaffe, David Sinclair, Rhonda Patrick, Thomas Delauer for years and years and probably spent the same amount of time as what it takes to complete a PhD myself. And my conclusion is: It's probably better to just do what makes you feel good because trying to strive for following any advice out there will 15 hours later be totally unvalidated by someone else's claims, referring to a completely opposite study. I also want to comment that it's hard in these times and ages to believe in studies that are heavily or even completely payed off by food and drug companies, which sadly seem to be almost every single one of the larger ones. This topic is probably one of the hardest one to solve since it involves trust in pharmaceutical industry with its 2022 worth in the US were about $846.72 Billion

It does not seem like Paul was interested in answering any questions during this interview. Paul says one thing, Derek asks a question, Paul won’t defend his stances and just says “you’re looking at it incorrectly”. And round and round and round

I have never heard of this electrolyte problem, and he didnt really explain it either.

@mcstootschris

2 ай бұрын

I have fasted for 7 days and my electrolytes went to shit. easiest ones i can name are salt, magnesium and potasium. I knew i was screwed because i started cramping up at the slightest muscle exertion

@brianparkman8183

2 ай бұрын

Bro science. No truth to it. Never heard anybody claim that from being in ketosis. I've never had a problem with it. And also the only one to hear him say in the ketosis camp about it being long term unhealthy. Just pulling that out of thin air.

@mcstootschris

2 ай бұрын

@@brianparkman8183 sounds like youre trying to out bro science me. Just shut the fuck bro.

@elliottrichardson8213

2 ай бұрын

He’s made a video on it search it up.

@Steve-ev6vx

2 ай бұрын

@@mcstootschris never had that issue. I have only gotten cramps when working in 100 degree plus heat all day. But I haven't ever tried to go 7 days without eating either. I can do one small meal a day, but I have to eat something.

I find these fad diets like carnivore or vegan or keto absolutely ridiculous. Truth is, the standard American diet is so bad, that any of these fad diets will be an improvement. However, earlier generations could live perfectly healthy by combining meat with veggies , carbs with fat, etc just find the balance and eat less and do sports. There is no need to deprive onself from anything as long as its with moderation

@Erik-leChef

2 ай бұрын

Absolutely. Very well said

@gp7110

2 ай бұрын

You know zero about shit other than common bullshit thats been fed to you. His research far outweighs yours, you aren’t listening.

@philippegerondeau4351

2 ай бұрын

So a little bit of coke here and there.

@justicericketts2912

2 ай бұрын

Vegan diet isn’t a fad diet, it’s a philosophical approach to an eating pattern, there is no one vegan diet or pattern. But other than that I do also dislike the fad diet approach to carnivore and keto and find it dangerous

@ianmacfarlane1241

2 ай бұрын

​@philippegerond 9:02 eau4351 Coca cola or cocaine? Or both?

@1:41:10 “it’s a gray area.” It doesn’t seem very gray considering the pharmacological intervention the Derek describes attentuates apoB and has a very minor side effect profile. It seems to me that if a pharmaceutical is tolerated well and lowers the risk of the #1 cause of mortality, it’s pretty no brainer. I could be wrong, though.

@sandymumkey7753

25 күн бұрын

Yeah when it got down to it Saladino's only defence was "you can't prove that it is safe long term" when you really can from most clinical data on Lipid lowering drugs especially the modern ones

I’m epileptic and yet to find a doctor speak about a Leto diet and want to find one.

I still don’t understand how any fully grown adult can honestly be convinced they cracked the code in ≤2 years of experimenting with any kind of specific diet

@bigaaron

26 күн бұрын

Hubris

Oh man Paul was getting irritated 😂

Uhh excuse me? Dude hasn’t posted in months and he has on Paul? Instant watch from me.

Appreciate Saladinos perspective and his ability to break down these atherosclerotic causes! Wow...wait. Paul's dads on blood pressure meds and statins. His dad had a stent but I had a triple bypass. I was just about to shit can my medications 😮

Ol’ Pauly Salads.

The standard American diet is full of seed oils, and most of MD influencers don't think that is a problem and only advise to "eath healthy" and exercise. But if what paul is claiming about seed oils and metabolic disfunction is true, his argument that no body of main stream MDs advise to fix metabolic disease/insulin resistance with dieting (stopping seed oil intake) is valid.

@august4633

2 ай бұрын

Same could be said about all the other claims that go against the scientific consensus made by pseudo-science social media influencers

@majdiawad1282

2 ай бұрын

​@august4633 you saying that I shouldn't put myself into Ketosis?

@balarab1

2 ай бұрын

​@@august4633 I did not defend his views, I only said his argument is valid because Derek didn't get hist point. On the contrary of pseudoscience, there are evidences that high rates of n6 polyunsaturated fats disrupts mitochondrial functions, which the standard American diet is full of.

@retwerts

2 ай бұрын

“Seed oil” is the new “demon food”, before that it was just “carbs” if you ask vegan it would be any animal based product. It’s all nonsense, nothing bad would happen to your body if you consume seed oils, the issue with seed oils is that they are just low in useful stuff while rich in calories. Just like most “unhealthy” food it really comes down to too many calories for too little micronutrients. Because of that you end up over feeding and gaining weight while still lacking sufficient fiber, minerals and vitamins.

Getting hung up on pharmacological intervention for managing lipids was painful. So many great things Paul was unable to talk about here due to how much time was spent on that. Silly.

ApoB is the sparks. The wood is the arterial walls. The insulin resistance is a gentle breeze all the way up to a wind.

His comments on Peter Attia endorsing seed oils and bad nutrition are crazy. He’s trying to provoke a fight so he can get publicity by debating his. But he seems to no understand what Attia actually says.

@Dwhizzle

2 ай бұрын

Yeah, he seems to be still holding onto a bunch of crazy ideas. Just slightly less crazy now.

@balarab1

2 ай бұрын

He did not say that, his argument is that seed oils are the main cause of metabolic disfunction and Peter Atteia is not advocating against seed oils and even saying the are benign.

@RyanABC123

2 ай бұрын

@@balarab1 I struggle like Derek to believe Attia says they’re benign and the implication was ok to consume.

@balarab1

2 ай бұрын

@@RyanABC123 Can we agree that if he doesn't advocate against them he doesn't see them as a significant factor in metabolic disfunction? Paul and others believe seed oils are the main cause of it and Peter and others don't and this was the argument

@animalbasedguy9488

2 ай бұрын

Peter Atia is too afraid to have his outdated lipid dogma challenged.

Diet and exorcize. I feel way better when I'm exercising even when I'm eating worse. Diet helps and i can tell i can better when I'm eating better but moving more had affected the way i look and feel and the data shows my anecdote is correct. This guy has always been a contrarian griftet. Listen to this dude and you can tell he's nervous all the time. He knows he's dishonest. He wouldn't look like he does if he didn't work out. No diet will do that and he fucking knows it

@Steve-ev6vx

2 ай бұрын

I have got to figure something out with exercise. I stopped walking/running/biking because the city has gotten crazy. You risk your life walking around in public now. I guess I'm going to have to get a gym membership, but I hated sports and PE and all that stuff, it's just reminder of all the stuff I sucked at. 😂

@polarig1030

2 ай бұрын

​@@Steve-ev6vxafter a few months of consistent exercise itll just be second nature. working out for me used to feel like a chore, but now its just.. something i do, and i enjoy doing it. it gets easier i promise u just gotta be consistent