I have noticed that some books put tyrosine with the polar amino acids and some books put tyrosine with the nonpolar amino acids. What my molecular biology professor said was that since the aromatic ring is so big and bulky, tyrosine is hydrophobic despite having that hydroxyl (so what he says in the video is correct, I'm just trying to help anyone who may still have doubts)

@oblomov4580

Жыл бұрын

Thank you! I got really confused cause i couldnt figure out how that is nonpolar considering it has OH group

@shivanibalodi9082

10 ай бұрын

It will be hydrophobic non polar only in that case, unless there are any exceptions I guess (that I am unaware of !)

Your videos are the perfect example for "everything is easier to memorize once you understand it". I would have fallen into despair without you!

Good

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Inexorable, very slow infinitesimal... As a guest, visitor etc

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I was'nt attending lectures for the whole semester...and now I'm able to understand everything..thanks alot (and the word "thanks" is'nt enough) :)

One of the best explanations I've heard thus far

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Thank you.

Excellent lectures. Clear, concise, and informative.

Thank you again for another fantastic lecture! I am no longer afraid of AAs!

@AKLECTURES

8 жыл бұрын

+Tammy Bush Yes! You're welcome Tammy!

Great lecture! On Valine, did you add an extra H atom to the first methyl group? I think it is CH not CH2, since C has four bonds. also Leucine

Absolute dedication, because he drew the bonds instead of using a skeletal formula for the R group

This was a really good lecture

I may have misunderstood, but Im sure all amino acids, apart from glycine are chiral

Sir in 2:04 did you mean to say that valine is more hydrophobic that alanine instead of saying ''more electronegative'' ?

There is a mistake in Valine, the first carbon atom of the side chain in ch, not Ch2

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Not all heroes wear capes

You state that Tyrosine is non-polar but that is incorrect.

You are truly a brilliant teacher Sir. Thank you for providing us with your awesome explanations 🙏😊

My lecturer told us that Tyrosine is hydrophilic, polar and uncharged...?

@hemavathithirumalai2855

7 жыл бұрын

same duobt ..here even..??

@strwrs3m64

5 жыл бұрын

Krupali Patel it depends. It’s only slightly hydrophilic

Thanks for an amazing lecture! But I have a question, you've classified Tyrosine as non-polar although in Lippincott it is categorized as polar. I do understand how you've explained it but still i'd be grateful if you looked into it. Thanks again!

Sir i think you forgot mentioning about proline as it is also shows hydrophobic nature

I have a question for Tyrosine. My lecture notes show that Tyrosine is actually hydrophilic due to its hydroxyl group. Which one is correct? Thanks!

@hassanhaider3441

7 жыл бұрын

I came across the same problem. In one of my biochemistry books, tyrosine is mentioned to be hydrophilic but in others it is said to be hydrophobic. Do not know why this happens :( And by the way, the books are Lippincott's Illustrated Review Of Biochemistry and and Harpers Illustrated Biochemistry.

@MaSSaDFTW

7 жыл бұрын

I think saying it's 'hydrophobic' and 'polar' is more accurate . the benzene ring makes it hydrophobic and the hydroxyl group makes it polar but it's not enough to make it hydrophilic , remember that polar does not always mean hydrophilic , think 'dichloromethane' for example , it's polar but it is not miscible with water 'hydrophobic'

@zootfitzgerald

6 жыл бұрын

Tyrosine has an ionizable hydroxyl group (pKa ~ 10.1 in proteins) which can form H-bonds. Thus, Tyrosine is amphipathic, having both hydrophobic and hydrophilic properties.

My textbook mentions proline as a non-polar as well, is there a reason for this?

does anyone have an idea if you can get pdf notes on what he explains?

I have a textbook that lists Tyrosine as neutral polar, I'm guessing that has soming with the o-h group.

@AKLECTURES

9 жыл бұрын

OurRandomLifeFTW Eh, thats not exactly wrong. But usually the single hydroxyl group is not enough to offset the large and bulky hydrophobic ring of tyrosine. Besides, that hydrogen ion is only lost at a very basic pH, making it not a very good acid at all.

@OurRandomLifeFTW

9 жыл бұрын

AK LECTURES thanks for the quick response and awesome lectures so far!

@AKLECTURES

9 жыл бұрын

OurRandomLifeFTW thank you! :-)

Great lecture ..thank you so much ..but l have one question please ..you say serine is polar and reactive in forming a disulfide bridge ..i think it is cystein not syrine ,isn't it?? I hope to respond to my comment...

your so good. thank you so much ur famous on our grad school campus!

@AKLECTURES

8 жыл бұрын

+Taio Duke Thats awesome :) Where do you go to school?

@taioduke2907

8 жыл бұрын

National University of Health Sciences. Lombard IL pursing doctorate in Naturopathic Medicine

Man you saved me from failing my Biochemistry course :)

Thank you so much for your great lectures! Just one small thing, would you check again a formula for valine and leucine?

why is the tyrosine with the hydrophobic group !?

For the valine structure in this video, I see that the CH2 carbon attached to the chiral carbon has 5 bonds. I think it should be CH and not CH2. Thank you for all you do.

Its not Serine the aminoacids that forms sulfide bridges but Cysteine instead:)

My notes show methionine is a polar,uncharged group..Is my notes wrong??

Hi! I was just wondering what was meant by some amino acids being more electronegative than others, as I thought this was a property of atoms, not molecules? Thanks! :-)

Which polar uncharged amino acids are most commonly involved in enzymatic reactions?

I still don't get why Tyrosine is non polar even though it has an OH

@medoviski3754

3 жыл бұрын

Check @backstreet fan comment

valine structure is wrong. that CH3 is not possible to be connected to 2 other CH3.

Tyrosine is polar not nonpolar🙄🙄

Do you think it's just a coincidence that there are 10 polar and 10 nonpolar amino acids?

biochem king !!!

@AKLECTURES

9 жыл бұрын

h ak thanks once again!

3:07 lol

3.07 helal helal

💛💛💛

I am sure you must be a teacher

Drglidden