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Question All of the following are excreted in cystinuria except:
a. Arginine
b. Leucine
c. Ornithine
d. Cystine
Correct Answer B
Explanation
Cystinuria is a hereditary condition characterized by the excessive excretion of certain amino acids in the urine. It specifically involves a defect in the renal tubular reabsorption of certain amino acids, leading to their increased excretion. The amino acids commonly involved in cystinuria are cystine, ornithine, arginine, and lysine. These are collectively known as the COLA amino acids.
To answer the question, we need to understand which of the listed amino acids is not excreted in excess in cystinuria:
a. Arginine: This is one of the amino acids commonly excreted in excess in cystinuria due to defective renal tubular reabsorption.
b. Leucine: This amino acid is not typically involved in cystinuria. Leucine is an essential amino acid, but it is not one of the amino acids that are poorly reabsorbed in the kidneys of individuals with cystinuria.
c. Ornithine: Like arginine, ornithine is also excreted in excess in cystinuria.
d. Cystine: As the name cystinuria suggests, cystine is one of the primary amino acids excreted in excess in this condition. It's notable for potentially forming crystals or stones in the kidneys and urinary tract.
Based on this information, the correct answer to the question "All of the following are excreted in cystinuria except" is b. Leucine. Leucine is not typically associated with the amino acid excretion pattern seen in cystinuria.