Medications for Managing CAR T Cell Adverse Effects outlines the pharmacological management of adverse effects associated with CAR T cell therapy, including the rationale, mechanisms of action, dosing, safety considerations, and drug interactions of medications such as anakinra, IVIG, dexamethasone, tocilizumab, and levetiracetam.
Key message: Several pharmacological strategies are available for managing adverse effects related to CAR T cell therapy; understanding each medication's mechanism of action, dosing, safety profile, and potential drug interactions will help to optimize patient care and outcomes.
Learning objective: Describe the mechanisms of action, dosing considerations, and potential adverse effects of key pharmacological agents used in managing adverse effects associated with CAR T cell therapy.
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