Is depression caused by a chemical imbalance?

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Link to article “The serotonin theory of depression: a systematic umbrella review of the evidence”: pubmed.ncbi.nlm.nih.gov/35854...
The idea that depression is related to a chemical imbalance has been around for several decades now, but is there any scientific evidence for it? Find out the truth about the serotonin hypothesis of depression in this video.
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Пікірлер: 35

  • @mrmotl1
    @mrmotl1 Жыл бұрын

    A chemical imbalance is a symptom or effect of a cause. An effect cannot be its own cause, it's very simple. A leaking hose with a hole in it can lead to flooding, but it wasn't the cause of the flood. The flood was caused by somebody who ran over the hose or animals chewing on it, causing the leak and the hole. Therefore the hose was in a destructive environment and that's what caused the flooding. What causes the chemical imbalance? The chemical imbalance is a physical symptom in the body as opposed to a psychological symptom of depression in the mind of which are both parallel symptoms of a greater cause in the overall environment. Such as no community, no support, stress and being overworked, trauma, government harassment and being in debt to this sick society. Society is sick and the environment is toxic, I could explain more but people wouldn't be open to the deep reflection and harsh truth that they would have to confront. Those banking off these problems caused by their system are in no way looking to change anything that might interfere with their profit margins. Therefore they sell you drugs to tell you to ignore the communicative signals your body is sending you and continue to work and run on the wheel that makes them money.

  • @klaudiar7347

    @klaudiar7347

    10 ай бұрын

    my thoughts as well...

  • @Rachel81690

    @Rachel81690

    4 ай бұрын

    Agreed

  • @olleharstedt3750
    @olleharstedt3750 Жыл бұрын

    Some suggest that "depression" is an umbrella term, and can be caused by many different things, just like fever. What about depression in bipolar disorder, for example? Or the possible link between depressive symptoms and low-grade chronic inflammation? I think it's too soon to say that depression _never_ has a purely biological cause. Not a doctor, tho. :)

  • @plockacherrys5765

    @plockacherrys5765

    Жыл бұрын

    Du har fel kompis

  • @irenemerinova6664

    @irenemerinova6664

    Жыл бұрын

    Almost all psychiatry disorders are not "illness* with causative agent, but rather spectrum of disintegration of functions.

  • @ViciousViscount
    @ViciousViscount Жыл бұрын

    SSRI's may not directly treat depression, but they sure can make it way more bearable and manageable. I know it's worked for me. I can finally get out of bed and have a somewhat more optimistic outlook on life.

  • @Seraphim222

    @Seraphim222

    Жыл бұрын

    That totally depends on person they never did shit for me

  • @Saj00724

    @Saj00724

    Жыл бұрын

    @@Seraphim222 did u tried multiple SSRIs? Zoloft made me manic, prozad made me apathetic but paxil and lexapro worked

  • @eyadsaleh12

    @eyadsaleh12

    Жыл бұрын

    Can Not agree more

  • @LDiamondz

    @LDiamondz

    8 ай бұрын

    They did nothing for me. Some of them made me even worse. Some gave me heart rhythm problems, some made me jittery, some interfered with my urinary system, some made me light headed, gave me headaches, huge weight gain, with no change in the deoression....Yeah, I've tried a LOT of different medications, and combinations of medications. Not one of them worked. I wish they did, I'd take them.

  • @JahBreed
    @JahBreed Жыл бұрын

    Mine was caused by spending years being led to my destruction by people I was supposed to be able to trust But yeah, Chemical Imbalance. My brain stopped using Seratonin properly and I almost killed myself with hormone replacement to skip possibly becoming dependant on the safe medications. It worked pretty well but sanity is fleeting while still in this giant mess that now, noone involved has the gonads to talk about on the record. Depression has many causes and comes with the risk of serious brain injury if it's ignored or not treated properly.

  • @JahBreed

    @JahBreed

    Жыл бұрын

    @Ai Da We need to bring more into this conversation. Finding things like the ongoing debate between Neuro and Psyche over the issue, individual denial, enabling the privileged to remain undiagnosed while holding court, etc. We need to start talking about how we got here, how to change, and less on puzzling over which of the thousand possibilities will be the one to fix everybody. I don't think that anyone in authority over this conversation would disagree if noone else was listening.

  • @dmackle3849

    @dmackle3849

    Жыл бұрын

    @@JahBreed look at all the options but pay extra attention to the ones that can’t be monetised. Those are the ones that will have disproportionately small research and marketing budgets. So we will need to listen extra hard to the possible mechanisms of action and should promote them in to common sense. Otherwise they will be crushed.

  • @shawnaford5540
    @shawnaford5540 Жыл бұрын

    Zoloft caused disability as it enhanced the anhedonia symptom of my depression. While it works for 30% of people, my disability was compounded by HCP’s saying to me “be patient, it take time”- after years of not resolving or getting relief. Patient Report Outcomes need to be the standard for depression treatment. Please do a video on PRC’s.

  • @adelinegaze344
    @adelinegaze3445 ай бұрын

    Depression is hell on earth. There is no other hell. All the spectrum of disability and guilt, like an never ending cirkle and all you want is to disappeare. I m finding ways for 23 years now...

  • @nathananderson8720
    @nathananderson87203 ай бұрын

    This is one of the channels that gave me the courage to start my KZread channel 11 months ago about self development. Now I have 2,132 subs and > 2k hours of watch time. I know it’s not comparable with others but I’m still proud I started because I’ve been learning so many lessons that I could haven’t learned without getting started in the 1st place.

  • @itamar.j.rachailovich
    @itamar.j.rachailovich Жыл бұрын

    First of all thanks for video. Can you please make a video about “sluggish cognitive tempo” (STC)?

  • @tabby73
    @tabby73 Жыл бұрын

    New subscriber here! Awesome content, I'm so happy to have found your channel. Clear explanations make it easy for me to learn about these topics. Thank you! Can you discuss the placebo effect please? I find it so interesting!

  • @petersteenkamp
    @petersteenkamp Жыл бұрын

    Depression isn't a disease, depression is a symptom. There are many diseases, disorders, and other causes that can cause depression. Some of them are medical, some are psychological and some are spiritual. Examples: a shortage in vitamin B1, shortage in vitamin B12, shortage in vitamin D3, shortage in certain minerals like Magnesium, untreated diabetes, several types of food allergies, some types of cancer, loss of a loved one, living under the influence of a bad person who goes out of his way to ruin your life, youth traumas, or having a shitty life with no hope of improvement. Etc. etc. The psychiatric narrative (in collaboration with the pharmaceutical industry) that depression is no more than a chemical imbalance in the brain is too stupid for words. It is irresponsible and dangerous because it ignores real diseases that could underly depression. For example, a woman came to a psychiatrist with depressive complaints. First, she got an SSRI, which didn't work. Then a heavier antidepressive, which also didn't work. Then she was advised to try electroshock, a treatment that is known to cause severe brain damage. Then someone else asked her about vitamin shortages. If, for example, you take off your shoes and stand on the floor, does it feel like you stand firm, or does it feel like you stand on a thick layer of cotton wool? This can point to a vitamin B12 shortage. For her, this was the case. A bottle of vitamin pills cured her depression in 3 days. Somebody else had a soy allergy: whenever she ate or drank soy, she would get an allergic reaction that lasted for weeks and made her depressed. If you have such a soy allergy, and you drink soy milk every few days, then the depression will be semi-permanent, until you stop eating or drinking what you are allergic to.

  • @stay60feetawayfromme33
    @stay60feetawayfromme33 Жыл бұрын

    Yes, just like almost every other disorder & ailment

  • @Camboo10
    @Camboo10 Жыл бұрын

    So prophylactic crutches?

  • @matthewwozniak9138
    @matthewwozniak9138 Жыл бұрын

    I'm not really down with the crutch route for treatment, but if something works, stick with it. I had a friend who took Zoloft and he seemed to like it. Unfortunately due to life circumstances he ended up taking his own life. I am uncertain about if he was on the medication or stopped taking it at that point in time. I'm totally against anything that is supposed to be helping you with depression with a warning disclaimer that it may cause thoughts of suicide.

  • @schevalirae

    @schevalirae

    Жыл бұрын

    Sorry for the loss of your friend. I have to wonder if you now know, 4 weeks later according to KZread, know if your friend had stopped the Zoloft before he took his own life. Having been depressed all my life from childhood trauma (watching violence between my parents, earliest memories) I finally found medicine that helped me in the 1990's, Effexor. I had tried various meds, including Zoloft. Then when my mom died in February 1995 followed by a stillborn son in October 1995, I went into a black hole of depression. Barely getting out of bed. Long story short, I took Effexor, even paying for it out of my own pocket when I worked in oil and gas but had no health insurance. Finally after being laid off in the Recession of 2008, I lost everything. By July 2009, I was suicidal and had to resume taking Effexor, which of course I no money for by then and had discontinued taking it. I was able to get the medication through the State of Texas Gulf Coast Center, where the cost was based on income. Since July 2009, I have taken 300 mg of Effexor ER (Extended Release) daily. The generic brand is called Venlafaxine. I can tell when I miss it. I've also survived 3 primary cancers and take various medications for other issues. I feel better than I ever have now at 61 years of age, and I have no problem with staying on the Venlafaxine the rest of my life. Much preferable to ever going back to that black hole of depression.

  • @centralpoint8184
    @centralpoint8184 Жыл бұрын

    How effective is ketamine in the long term

  • @robmehlenbacher402
    @robmehlenbacher402 Жыл бұрын

    As a soon-to-be-provider, how does one address patient ambivalence regarding psychopharmacology?

  • @olleharstedt3750

    @olleharstedt3750

    Жыл бұрын

    Motivational interview techniques?

  • @shawnleong3605

    @shawnleong3605

    Жыл бұрын

    Don’t try to be a pill pusher. Work on yourself and whether you are doing it in good conscience despite the fact that so many of us, me included, are suffering. Consider rethinking your stance and the modern scientific way of conceptualising health.

  • @hahaha9076
    @hahaha9076 Жыл бұрын

    Great information, I've long held a suspicion that doctors were reading from a script about this. I have a daughter on antidepressants. The problem I see with medication is that it forms in the mind of the patient that this is the reason and cure. Giving some relief for sure. Human beings are powerful creatures. The mind is chemical, electrical but also mechanical. The subconscious is downloaded or programmed early in life. What goes in is out of our control. We are not responsible that. However, just like any library or computer you can over time add programming that is beneficial or harmful. You cannot run office related files without downloading a program for that purpose. Many people follow the subconscious program without knowing how or what to add. For instance, if you're early experiences are doom, your subconscious will tend towards more of it. Many people are focusing on the doom or hopelessness of humanity, therefore strengthening the subconscious script of such. Strengthening neural pathways in the brain. Google mechanics of the mind. There are loads of scientific studies today proving "your" reality can be whatever you choose for yourself. The world doesn't change, but your world can. The subconscious will challenge your conscious attention to new thoughts because it is designed to keep you safe in what it's beliefs have become so far. It's not just the mind you need to focus on. Diet, sugar is causing every part of your body to be compromised. Exercise, lack of it allows the body to self destruct. Sleep, needs to be structured, patterned. Medication can cause us to put our faith in one thing, it. There are no silver bullets. Pay attention to everything. How do I know? At 60 I am happy, balanced and have real hope after 2 years of being on this path. The mind is powerful, you can do anything you believe you can.

  • @SiddharthSingh-up2gs

    @SiddharthSingh-up2gs

    Жыл бұрын

    I want to marry your daughter. both of us would be in anti depressants so we could care each other more.

  • @oscardarrell83
    @oscardarrell83 Жыл бұрын

    ..and chemical imbalance caused by depression..oh goshhh

  • @user-wg6im5th7r
    @user-wg6im5th7r6 ай бұрын

    Its a western self induced inbalance

  • @HasanAlKharfan
    @HasanAlKharfan7 ай бұрын

    What do you think about the studies mentioning how lower/dysfunctional activity of the left dorsolateral prefrontal cortex could be a major contributor to depression and that electromagnetic stimulation of the area might "help a lot" if not "potentially cure depression"