Intro to Reaction Mechanisms: Crash Course Organic Chemistry #13

When we venture to new places, we need navigational tools to guide us. In organic chemistry, those are reaction mechanisms! In this episode of Crash Course Organic Chemistry, we’ll learn all about how to write reaction mechanisms. Having this super useful skill means we don’t have to worry about memorizing every reaction that has ever existed.
Series Sources:
Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.
***
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Пікірлер: 105

  • @drakesmith471
    @drakesmith4713 жыл бұрын

    To anyone who hasn’t studied Organic Chemistry a bit, forewarning it’ll be bad at first, but it will get better. Mostly I mean reaction mechanisms here but in general. You’ll feel more satisfied and more motivated the more you go on.

  • @jamaiya7
    @jamaiya73 жыл бұрын

    this is where o-chem all went downhill for me 🥴

  • @MoMn.
    @MoMn.3 жыл бұрын

    Production values are exceptional. Huge respect to your awesome animators

  • @SuperAndrewlove

    @SuperAndrewlove

    3 жыл бұрын

    Aw thank you! This made me smile :)

  • @mathfincoding
    @mathfincoding3 жыл бұрын

    I lost track of what's happening 10 episodes ago. This isn't even my major. I don't know why I'm still watching 😂

  • @alic4631

    @alic4631

    3 жыл бұрын

    Well this is major and i lost track too 😂

  • @marinabarros1721
    @marinabarros17213 жыл бұрын

    omg you're such a good teacher. I've already had all my org chem classes and I still don't understand a lot of the basic stuff. My teachers actually didn't bother to teach us this :/

  • @ishikasingh9254
    @ishikasingh92543 жыл бұрын

    You guys, seriously, LIVE SAVIOURS. My organic chemistry course is starting next week. Can you imagine my sheer relief at seeing this course on ur channel? Thanks!

  • @firefx963
    @firefx9633 жыл бұрын

    I just can't take my eyes off of the background colors matching in yellow.. 😂

  • @zulanova1209
    @zulanova1209 Жыл бұрын

    FINALLY, I GET IT thank you ever so much that was a wonderful and clear explanation, and the visuals really helped

  • @ICantSeeYourRepliesDickhead
    @ICantSeeYourRepliesDickhead Жыл бұрын

    Man I'd never miss class, thank you for your help!

  • @terrabelle9937
    @terrabelle9937 Жыл бұрын

    So, so grateful for the people at Crash Course.

  • @cnc321
    @cnc3213 жыл бұрын

    You are AMAZING! I'm taking Ochem 2 and this is such a helpful refresher for the small details

  • @user-ue6rk9by1j
    @user-ue6rk9by1j3 жыл бұрын

    Just in time for my quiz later. Thank you.

  • @believer922
    @believer9223 жыл бұрын

    Wow 🤩😲very informative video!!!!

  • @iamadarshamrit
    @iamadarshamrit3 жыл бұрын

    This channel is a savior when It comes to reviewing for my exams.

  • @onelittlestep88
    @onelittlestep883 жыл бұрын

    Thank you Crash Course, you give me something new in this video. XD

  • @vikramkc2219
    @vikramkc221910 ай бұрын

    Great teacher ❤

  • @abhi-wi2mj
    @abhi-wi2mj3 жыл бұрын

    i love you crash course💚

  • @abhi-wi2mj
    @abhi-wi2mj3 жыл бұрын

    i love mechanisms , its so logical and fun

  • @bizzarex5275
    @bizzarex52753 жыл бұрын

    Thanks for uploading new video.

  • @henryelicker2403
    @henryelicker24033 жыл бұрын

    I wonder what the mechanism is for "Turn the O2 into the O3, dawg".

  • @mortuos557

    @mortuos557

    3 жыл бұрын

    Google the Chapman cycle!

  • @snowballeffect7812
    @snowballeffect78123 жыл бұрын

    This is such an excellent educational tool.

  • @benjaminstandefer9015
    @benjaminstandefer90153 жыл бұрын

    Thank you for the video. Have you ever considered creating a course oriented more towards mathematics? I am an avid fan of your videos, but often have to turn to other resources for mathematical help.

  • @crashcourse

    @crashcourse

    3 жыл бұрын

    Math is definitely a tricky one for us. We've made a couple attempts - Statistics here on this channel & this summer we did Alegbra with ASU. But who knows, maybe down the line we'll try other math coures! -NS

  • @nadyahginicecaballero7185
    @nadyahginicecaballero71853 жыл бұрын

    just in time for my orgchem quiz this friday

  • @Rahulshorts124
    @Rahulshorts1243 жыл бұрын

    Thanks so much

  • @Dmplivemail
    @Dmplivemail3 жыл бұрын

    It would be so great if after this classes we had some exercises...

  • @gg3675

    @gg3675

    3 жыл бұрын

    If you download the app they have some "notecards" that I've actually found very helpful.

  • @anjanaprabhash.z3031
    @anjanaprabhash.z30316 ай бұрын

    Thanks now I get it

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    @mark_tilltill66643 жыл бұрын

    Really like arrow pushing!

  • @harshgumma8074
    @harshgumma8074 Жыл бұрын

    I have a question: According to the reaction mechanism isn’t the reverse reaction also possible for all reactions Take benzyl chloride for example. We can draw a reaction mechanism for the given reaction C6H5CH2Cl + H2O = C6H5CH2OH + HCl But we can also do the same for the reverse reaction which is not possible in real life. So how do we know if the given reaction mechanism will actually happen?

  • @jacobkelly677
    @jacobkelly677 Жыл бұрын

    Why doesn't the HSO4 negative charge attack the carbocation more readily than the water? Steric hinderance?

  • @firstmkb
    @firstmkb3 жыл бұрын

    Excellent presentation, thanks.

  • @DailyDoseDocumentary
    @DailyDoseDocumentary3 жыл бұрын

    Nice piece.

  • @DailyDoseDocumentary

    @DailyDoseDocumentary

    3 жыл бұрын

    Great explanation of Reaction Mechanisms.

  • @DailyDoseDocumentary

    @DailyDoseDocumentary

    3 жыл бұрын

    @@FlamingBasketballClub We publish short documentary-style films usually 3-minutes or less Monday - Friday!

  • @SciFactsYT118
    @SciFactsYT1183 жыл бұрын

    Random fact: Blue whale tongues can weigh as much as an elephant.

  • @Hambxne

    @Hambxne

    3 жыл бұрын

    When it comes to pee production, whales are world champs. A single fin whale is thought to produce around 1,000 liters (260 gallons) of urine each day - enough to fill a 10-by-6-foot kiddie pool.

  • @lycaonpictus4433

    @lycaonpictus4433

    3 жыл бұрын

    @@Hambxne and i would like to add ... And all the water they get is from their food they can't drink sea water So it means if they starve they also are dehydrated Edit: some species of whales will not eat seasonally , they get the water from their fat stores/blubber When you burn fat you get energy Which gets converted to heat , co² , and water .

  • @sillypoint2292
    @sillypoint22923 жыл бұрын

    I really love organic a lot😘🥰😍

  • @erinaldrich8016
    @erinaldrich80163 жыл бұрын

    When can we expect more episodes?

  • @jennadodge6924
    @jennadodge6924 Жыл бұрын

    I got most of it but what happened to the HSO4? Why was it not added to the reaction

  • @whengale
    @whengale Жыл бұрын

    The acetylide salt + cyclohexanol reaction is probably occurring in aqueous solution, otherwise the salt wouldn't dissociate, right? So why doesn't the acetylide ion attack the protons in the H2O molecules instead? Is it because the carbonyl's δ+ carbon atom is somehow more electrophilic than the hydrogen atoms in the water? The bonds in water have an electronegativity difference of ~1.2, and the carbonyl double-bond has an electronegativity difference of ~1. So why is it that, in this reaction, water's protons are less attractive to the acetylide ions than the electrophilic carbon in cyclohexanone?

  • @whengale

    @whengale

    Жыл бұрын

    I understand that water is formally excluded from the first step in the reaction & that this is just a pedagogical proof of concept, but in a real situation, how would I be able to *predict* that the acetylide would attack the δ+ carbon atom instead of one of the *more* δ+ protons in H2O?

  • @whengale

    @whengale

    Жыл бұрын

    ok I just read on Wikipedia that the reaction is usually done in liquid ammonia, which is a nucleophile & so would not be attacked by the acetylide. I guess I answered my own question lol.

  • @QuestionEverythingButWHY
    @QuestionEverythingButWHY3 жыл бұрын

    “The mind is not a vessel to be filled, but a fire to be kindled.” ― Plutarch

  • @alexisperry4555
    @alexisperry4555 Жыл бұрын

    Wish I had this for orgo 1. I barely passed with a B but im stuck in orgo 2 Thanks

  • @ramjayadeepb6861
    @ramjayadeepb68613 жыл бұрын

    Corona:"I spread fast" Me: "not faster than crash course views"😎

  • @prem5176

    @prem5176

    3 жыл бұрын

    Mmmm, no there are many other channels get more views in less time

  • @ramjayadeepb6861

    @ramjayadeepb6861

    3 жыл бұрын

    @@prem5176 yup

  • @emacuhara5635
    @emacuhara56353 жыл бұрын

    Yay, app!

  • @sillypoint2292
    @sillypoint22923 жыл бұрын

    Hey are u from India? I'm from India! Love u guys!

  • @BassikMusic
    @BassikMusic3 жыл бұрын

    Ah, the things nightmares are made of

  • @ajay-vlogger
    @ajay-vlogger3 жыл бұрын

    I can't stop hearing her name again and again. Nice name.

  • @aceroro21
    @aceroro21 Жыл бұрын

    why is water still floating? i’ve never been able to grasp why it is still there

  • @ivanmayerle1333
    @ivanmayerle13333 жыл бұрын

    Soooo gooood! Can you show us elimination of N2 form amines (by HNO2) . I thinks that it s very interesting reaction. Good luck

  • @margaretgodfrey9946
    @margaretgodfrey99463 жыл бұрын

    They use my own professor's book for the videos so this really works for my class

  • @5ive8ight
    @5ive8ight3 жыл бұрын

    To the person that’s reading this: You’re very intelligent and adorable human! Stay healthy during quarantine My Dream is to have 70k. I been struggling to get there💚

  • @franck1919
    @franck19193 жыл бұрын

    11:45 I loved the phrase "Don't panic" that makes me remember the cover of Hitchhiker guide to the galaxy book. Like if you read that awesome book. Nice content. Leave my like.

  • @wada-wada
    @wada-wada3 жыл бұрын

    why do you input an empty line before every line of your subtitles?

  • @ajay-vlogger
    @ajay-vlogger3 жыл бұрын

    Ohhhhhhhhhhhhh !!!!! 16th comment I love CrashCourse.

  • @afrnn
    @afrnn8 ай бұрын

    cant understand a thing 😭😭

  • @manaswikumar4969
    @manaswikumar4969 Жыл бұрын

    That warning sign was scary

  • @benrobinett3396
    @benrobinett33963 жыл бұрын

    Idk if I’ve ever been this early

  • @getrektfn5725
    @getrektfn57253 жыл бұрын

    “Who else is reading comments and not watching in full screen?😂” *(Hey CrashCourse thanks for commenting on my new video)❤️*

  • @firefx963

    @firefx963

    3 жыл бұрын

    hello

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    @edwardcasillas153

    3 жыл бұрын

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    @ZubairAli-ns7vr3 жыл бұрын

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  • @benscrafield9575
    @benscrafield95753 жыл бұрын

    A few misleading things in this video. First of all a lot of the structures are not great: molecular geometries were wrong for sulfuric acid and H3O+, and there’s the tendency to show square-planar-type structures for organic molecules - obviously people do this for the purpose of teaching, but then when you want to show a mechanism, e.g. an elimination, you need to introduce another method of representation for it to make sense. Speaking of which, the reversible hydration/dehydration would surely give the E alkene as the major alkene component, very quickly. As presented in the video, it makes it look like you would have a mixture of the Z alkene and the alcohol, which effectively would not be true. Also the reference to pKa was quite odd: why state that the protonated alcohol has a low pKa if it’s not going to be compared to H3O+ in the forward direction?

  • @josenellandrewtumulak2400
    @josenellandrewtumulak24003 жыл бұрын

    Dope

  • @brynwhitehead1731
    @brynwhitehead17313 жыл бұрын

    Hot Mic. So, to the business of business.

  • @QuestionEverythingButWHY
    @QuestionEverythingButWHY3 жыл бұрын

    “Wonder is the seed of knowledge” ― Francis Bacon

  • @ShauryaSingh-ts2oc

    @ShauryaSingh-ts2oc

    3 жыл бұрын

    Just stop...it's more like spamming now

  • @JS-vv3mo
    @JS-vv3mo3 жыл бұрын

    in the next video,deboki di plz try to explain the diff. btw inductive ,electromeric,mesomeric n hyperconjugation....really it ll help me a lot...🙏

  • @QuestionEverythingButWHY
    @QuestionEverythingButWHY3 жыл бұрын

    "Be less curious about people and more curious about ideas." -- Marie Curie

  • @sarthakpeepra3748
    @sarthakpeepra37483 жыл бұрын

    can i get a shout out?

  • @nooraoude1000
    @nooraoude1000 Жыл бұрын

    she looks like camilla cabello

  • @culwin
    @culwin3 жыл бұрын

    Most people driving don't seem to know what a Yield sign means.

  • @sebfetea3408
    @sebfetea34083 жыл бұрын

    I am an unreactive mechanism

  • @vaughnjohnson8767
    @vaughnjohnson87673 жыл бұрын

    Organic Chemistry explained by Marvel: Chemistry: Nucleophilic War Chemistry: Endgame

  • @haileyhua4468
    @haileyhua44683 жыл бұрын

    I hate school

  • @youre_totally_right_but_
    @youre_totally_right_but_3 жыл бұрын

    27 seconds gang

  • @karlbergen6826
    @karlbergen68263 жыл бұрын

    Organic reactions tend to proceed to give multiple products. Usually one of.the products is a polymeric material often called tar.

  • @mariemartinez7121
    @mariemartinez71213 жыл бұрын

    Me watching their videos from 2013...

  • @jorgeherrera-uo2pr
    @jorgeherrera-uo2pr3 жыл бұрын

    Diversity!!!! In your hosts we love to see it!!!

  • @angusjulie9701
    @angusjulie97013 жыл бұрын

    When will crash course Asian and African history come.

  • @AInova.2

    @AInova.2

    3 жыл бұрын

    Wait

  • @abdullahmusa9547
    @abdullahmusa95473 жыл бұрын

    Almost First

  • @TheKilerbg
    @TheKilerbg3 жыл бұрын

    Early birds post the first comments

  • @patrickpowell601
    @patrickpowell6013 жыл бұрын

    When did science look so damn good 🤤

  • @traceycook7136
    @traceycook71363 жыл бұрын

    I thought I was going to finally learn how to drive uggg...

  • @aryansingh7209
    @aryansingh7209 Жыл бұрын

    When your organic chem teacher doesn't teach you properly!

  • @justinanderson267
    @justinanderson2673 жыл бұрын

    Oy You lost me at electrophilic additions of a protein to an alkaline. I need to go back over my high school chemistry lol

  • @beepk9228
    @beepk92283 жыл бұрын

    Can you guys please bring back Human Geography T_T

  • @Syncronicity888
    @Syncronicity888 Жыл бұрын

    Way over my simple mind.

  • @chrisfit
    @chrisfit3 жыл бұрын

    So tired of reaction videos.

  • @AInova.2
    @AInova.23 жыл бұрын

    Focus on the problem rather focusing on theories in organic chemistry .we need much practice to familiar with OC.

  • @Spit823
    @Spit8233 жыл бұрын

    The real life map analogy is so unnecessary. Can’t we just get to the point?

  • @ZelenoJabko
    @ZelenoJabko3 жыл бұрын

    Sorry, you are what?