Imagining CRISPR Cures | Fyodor Urnov | TEDxBerkeley

Fyodor Urnov explores the future of CRISPR and how it has the potential to save lives. Professor Fyodor Urnov is a Professor of Molecular and Cell Biology at the University of California, Berkeley, and is a Director at its Innovative Genomics Institute, leading the Center for Translational Genomics and directing the Technology & Translation division. A pioneer in the field of therapeutic genome editing, Fyodor’s research focuses on advancing genome editing technology and pushing the boundaries of how it can be applied to solve real-world biomedical problems. In his work at Sangamo Therapeutics (2000-16), Fyodor and colleagues demonstrated the first use of native gene editing in human cells and coined the term “genome editing.” Fyodor then led collaborative teams to establish at-scale applications of genome editing for human somatic cell genetics and model animal and crop reverse genetics. Fyodor was a key member of the team that developed the first-in-human clinical application of genome editing (2009), and then led a from basic discovery to clinic an approach to use gene editing to treat the hemoglobinopathies, beta-thalassemia and sickle cell disease, that has resulted in sustained clinical benefit for over 70 individuals. At the IGI, Fyodor focuses on establishing turnkey editing of the human genome for clinical use and make CRISPR-based treatments for genetic disease broadly and equitably available on-demand. He works in collaborative teams to develop first-in-human applications of experimental CRISPR-based therapeutics for sickle cell disease, genetic disorders of the immune system, radiation injury, neuroinflammation, and neurological disorders. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

Пікірлер: 55

  • @bikojalal3120
    @bikojalal3120 Жыл бұрын

    I have a son he has been diagnosis with Ethylmalonic encephalopathy disease which is less than hundred people in the world they have this disease. My son is four years and eight months old he is mildly affected. Our hope is this gene therapy will be available soon and it can save our sons life.

  • @esaiqwerty
    @esaiqwerty2 жыл бұрын

    Raise awareness. This is the future.

  • @robdev89
    @robdev898 ай бұрын

    Every day my mind is blown by our Technologies and passionate people in the world, making these things possible. Thankfully the good guys do eventually find their way. 🎉

  • @maxthelionxmax9220
    @maxthelionxmax9220 Жыл бұрын

    This is excellent. No one knows who will develop a disease in the future. It’s important the solution is there before not after

  • @BearMeat4Dinner
    @BearMeat4Dinner Жыл бұрын

    Dr. Doudna ❤

  • @sanjaychoudhary8849
    @sanjaychoudhary8849 Жыл бұрын

    Your speak made me cry at the beigning

  • @MrDigantvora
    @MrDigantvora Жыл бұрын

    Thank you for information and bringing awareness of "Health Justice". Health justice is necessary because it, all we would be left with INFINITE GREED OF UNSUSTAINABLE HUMAN SOCIETY

  • @rickidhal3950
    @rickidhal3950 Жыл бұрын

    Thank you for championing the possibility of cure, I watched this with a ton of hope. I have to say your words are powerful but it's extremely hard to impossible to find anyone on this planet who can offer cure via crispr now. Just a bunch of videos saying we must do this. There are illnesses that can be cured now but it doesn't happen. Probably won't happen in the lifetime for many people dying right now. How do we really change this now?

  • @madhu_1489

    @madhu_1489

    Жыл бұрын

    They just advertise for to get investors attention. That all nothing more!

  • @PedroDeBandit

    @PedroDeBandit

    8 ай бұрын

    We hope that someone like Jeff Bezos comes to understand that he can't take his money with him 🙏

  • @lexwil1689
    @lexwil1689 Жыл бұрын

    I am a dialysis patient and I know this would reverse the actions of kidney disease

  • @squamish4244
    @squamish42447 ай бұрын

    "O for a Muse of fire, that would ascend. The brightest heaven of invention"

  • @dancar2537
    @dancar25376 ай бұрын

    we are going to automate medicine and this is going to get easy

  • @LuisOrtiz-ey1bp
    @LuisOrtiz-ey1bp Жыл бұрын

    What about for autism and global development delays/disabilities?

  • @questmarq7901

    @questmarq7901

    Жыл бұрын

    Paste gene editing, look it up

  • @NicoleDaly-jq4db
    @NicoleDaly-jq4dbАй бұрын

    Is CRISPR being studied for use in Familial Adenomatous Polyposis patients yet?

  • @srin8116
    @srin8116 Жыл бұрын

    👍

  • @semrabahcivan8627
    @semrabahcivan8627 Жыл бұрын

    I have Thallasaemia heterogeneous, Hyperthyroidism, Sjogren, autoimmune diseases, kidney stones, vascular retinal occlusion. Can I get any treatment ?

  • @charlesbaha5298
    @charlesbaha52989 ай бұрын

    Wouldn’t this be easy to fix NF1?

  • @johndaly6497
    @johndaly64972 жыл бұрын

    Need allogenic options.

  • @OneOfMany111
    @OneOfMany111 Жыл бұрын

    👽♥️🕊️

  • @taylortischhauser4414
    @taylortischhauser4414 Жыл бұрын

    Love the idea of CRISPR in a perfect world, but this brings up concerns and raises important questions about access and equity. If gene editing becomes widely available, it could create new forms of social and economic inequality, with only the wealthy and privileged able to afford the treatments and enhancements that come with CRISPR technology.

  • @juliahello6673

    @juliahello6673

    7 ай бұрын

    He literally just talked about how to make it affordable. I swear, Americans have watched too many movies and think that movie plots occur in real life.

  • @akhiy5384
    @akhiy5384 Жыл бұрын

    I have PTSD and i want to erase my trauma .i don't my future children to not have any kind of disease😭

  • @lucid0443

    @lucid0443

    Жыл бұрын

    i hope you’re re joking

  • @jaqueitch
    @jaqueitch2 жыл бұрын

    Indeed, Bluebird Bio is bound for bankruptcy

  • @YouTube_Enjoyerlol
    @YouTube_Enjoyerlol Жыл бұрын

    I just want to genetically engineer myself to stop aging after the age of 25 😆 👌 let’s gooooo

  • @nmbr1ctrman
    @nmbr1ctrman Жыл бұрын

    Weaponizing Crispr seems to be a big issue in the future as well

  • @religionisapoison2413

    @religionisapoison2413

    Жыл бұрын

    Yeah like editing a SARs virus..... And making billions of dollars for you and your buddies while it spreads around the world

  • @questmarq7901

    @questmarq7901

    Жыл бұрын

    This is the last of our problem. We need gene therapy asap

  • @nmbr1ctrman

    @nmbr1ctrman

    Жыл бұрын

    @@questmarq7901 won't matter if someone creates a super virus and destroys humanity.

  • @sanjaychoudhary8849

    @sanjaychoudhary8849

    Жыл бұрын

    ​@@questmarq7901 so true

  • @lttrhd
    @lttrhd9 ай бұрын

    What about a schizophrenia?

  • @jebediahconde2143
    @jebediahconde2143 Жыл бұрын

    Can we crisper out the speakers mouth noises?

  • @aj-uo3uh

    @aj-uo3uh

    Жыл бұрын

    Can we crisper out you?

  • @jebediahconde2143

    @jebediahconde2143

    Жыл бұрын

    @@aj-uo3uh nope. Here to stay

  • @aj-uo3uh

    @aj-uo3uh

    Жыл бұрын

    @@jebediahconde2143 Ok fine, please behave then.

  • @lttrhd

    @lttrhd

    9 ай бұрын

    The topic is too serious to concentrate on speaker noises

  • @imagreatguy1250
    @imagreatguy12502 жыл бұрын

    This is the 4th comment. Shit's RARE...

  • @documentedrecords5364
    @documentedrecords5364 Жыл бұрын

    Imagine.......CRISPR CURES!..... Me: Yeah, keep imagining idiots

  • @JZGreengo

    @JZGreengo

    Жыл бұрын

    It’s like call of duty releases, im not hyped for the next one and I’m most likely not hyped for this, im not crashing on that train like the stem cell one

  • @PedroDeBandit
    @PedroDeBandit8 ай бұрын

    Jeff Bezos... are you listening...

  • @Hunter_Bidens_Crackpipe
    @Hunter_Bidens_Crackpipe Жыл бұрын

    I can’t deal with the lip smacking. I want to watch this but it’s to much to handle

  • @completelybraindead
    @completelybraindead Жыл бұрын

    This guy needs a glass of water or something. His mouth sounds dry af.

  • @ii-lr5mn

    @ii-lr5mn

    Жыл бұрын

    😂

  • @yvonnecarter4118
    @yvonnecarter4118 Жыл бұрын

    Stop swallowing into the mike. It sounds dreadful and prevent me from listening 😢

  • @lttrhd

    @lttrhd

    9 ай бұрын

    Turn off sound, turn on CC

Келесі